Zeljko M Svedružić

Zeljko M Svedružić

UNVERIFIED PROFILE

Are you Zeljko M Svedružić?   Register this Author

Register author
Zeljko M Svedružić

Zeljko M Svedružić

Publications by authors named "Zeljko M Svedružić"

Are you Zeljko M Svedružić?   Register this Author

11Publications

268Reads

In silico design of the first DNA-independent mechanism-based inhibitor of mammalian DNA methyltransferase Dnmt1.

PLoS One 2017 11;12(4):e0174410. Epub 2017 Apr 11.

Laboratory for Biomolecular Structure and Function, Department of BioMedical Technology, Center for Advanced Computing and Modelling (CNRM), University of Rijeka, Rijeka, Croatia.

View Article
September 2017

Decrease in catalytic capacity of γ-secretase can facilitate pathogenesis in sporadic and Familial Alzheimer's disease.

Mol Cell Neurosci 2015 Jul 4;67:55-65. Epub 2015 Jun 4.

Medical Biochemistry, PB Rab, Faculty of Medicine, University of Rijeka, Rab, Croatia; Neurology and Geriatrics, PB Rab, Faculty of Medicine, University of Rijeka, Rab, Croatia.

View Article
July 2015

Modulators of γ-secretase activity can facilitate the toxic side-effects and pathogenesis of Alzheimer's disease.

PLoS One 2013 7;8(1):e50759. Epub 2013 Jan 7.

Medical Biochemistry, PB Rab, Faculty of Medicine, University of Rijeka, Rab, Croatia.

View Article
July 2013

Modulation of γ-secretase activity by multiple enzyme-substrate interactions: implications in pathogenesis of Alzheimer's disease.

PLoS One 2012 30;7(3):e32293. Epub 2012 Mar 30.

Medical Biochemistry, Faculty of Medicine, University of Rijeka, Rab, Croatia.

View Article
August 2012

Dnmt1 structure and function.

Prog Mol Biol Transl Sci 2011 ;101:221-54

Medical Biochemistry, PB Rab, Faculty of Medicine, University of Rijeka, Rab, Croatia.

View Article
August 2011

Mammalian cytosine DNA methyltransferase Dnmt1: enzymatic mechanism, novel mechanism-based inhibitors, and RNA-directed DNA methylation.

Curr Med Chem 2008 ;15(1):92-106

Department of Biophysics and Biochemistry, Washington State University, Pullman, WA 99164, USA.

View Article
April 2008

Interaction between mammalian glyceraldehyde-3-phosphate dehydrogenase and L-lactate dehydrogenase from heart and muscle.

Proteins 2006 May;63(3):501-11

Department of Biochemistry and Molecular Biology, 246 B Noble Research Center, Oklahoma State University, Stillwater, Oklahoma 74078, USA.

View Article
May 2006

Accommodation and repair of a UV photoproduct in DNA at different rotational settings on the nucleosome surface.

J Biol Chem 2005 Dec 6;280(48):40051-7. Epub 2005 Oct 6.

Department of Biochemistry and Biophysics, School of Molecular Biosciences, Washington State University, Pullman, Washington 99164-4660, USA.

View Article
December 2005

Mechanism of allosteric regulation of Dnmt1's processivity.

Biochemistry 2005 Nov;44(45):14977-88

Department of Chemistry and Biochemistry and Program in Biomolecular Science and Engineering, University of California, Santa Barbara, California 93106, USA.

View Article
November 2005

DNA cytosine C5 methyltransferase Dnmt1: catalysis-dependent release of allosteric inhibition.

Biochemistry 2005 Jul;44(27):9472-85

Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA.

View Article
July 2005

The mechanism of target base attack in DNA cytosine carbon 5 methylation.

Biochemistry 2004 Sep;43(36):11460-73

Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA.

View Article
September 2004