Zeljko M Svedružić

Zeljko M Svedružić

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Zeljko M Svedružić

Zeljko M Svedružić

Publications by authors named "Zeljko M Svedružić"

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11Publications

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In silico design of the first DNA-independent mechanism-based inhibitor of mammalian DNA methyltransferase Dnmt1.

PLoS One 2017 11;12(4):e0174410. Epub 2017 Apr 11.

Laboratory for Biomolecular Structure and Function, Department of BioMedical Technology, Center for Advanced Computing and Modelling (CNRM), University of Rijeka, Rijeka, Croatia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0174410PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388339PMC
September 2017

Decrease in catalytic capacity of γ-secretase can facilitate pathogenesis in sporadic and Familial Alzheimer's disease.

Mol Cell Neurosci 2015 Jul 4;67:55-65. Epub 2015 Jun 4.

Medical Biochemistry, PB Rab, Faculty of Medicine, University of Rijeka, Rab, Croatia; Neurology and Geriatrics, PB Rab, Faculty of Medicine, University of Rijeka, Rab, Croatia.

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http://dx.doi.org/10.1016/j.mcn.2015.06.002DOI Listing
July 2015

Dnmt1 structure and function.

Prog Mol Biol Transl Sci 2011 ;101:221-54

Medical Biochemistry, PB Rab, Faculty of Medicine, University of Rijeka, Rab, Croatia.

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http://dx.doi.org/10.1016/B978-0-12-387685-0.00006-8DOI Listing
August 2011

Mammalian cytosine DNA methyltransferase Dnmt1: enzymatic mechanism, novel mechanism-based inhibitors, and RNA-directed DNA methylation.

Curr Med Chem 2008 ;15(1):92-106

Department of Biophysics and Biochemistry, Washington State University, Pullman, WA 99164, USA.

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April 2008

Interaction between mammalian glyceraldehyde-3-phosphate dehydrogenase and L-lactate dehydrogenase from heart and muscle.

Proteins 2006 May;63(3):501-11

Department of Biochemistry and Molecular Biology, 246 B Noble Research Center, Oklahoma State University, Stillwater, Oklahoma 74078, USA.

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http://dx.doi.org/10.1002/prot.20862DOI Listing
May 2006

Accommodation and repair of a UV photoproduct in DNA at different rotational settings on the nucleosome surface.

J Biol Chem 2005 Dec 6;280(48):40051-7. Epub 2005 Oct 6.

Department of Biochemistry and Biophysics, School of Molecular Biosciences, Washington State University, Pullman, Washington 99164-4660, USA.

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http://dx.doi.org/10.1074/jbc.M509478200DOI Listing
December 2005

Mechanism of allosteric regulation of Dnmt1's processivity.

Biochemistry 2005 Nov;44(45):14977-88

Department of Chemistry and Biochemistry and Program in Biomolecular Science and Engineering, University of California, Santa Barbara, California 93106, USA.

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http://dx.doi.org/10.1021/bi050988fDOI Listing
November 2005

DNA cytosine C5 methyltransferase Dnmt1: catalysis-dependent release of allosteric inhibition.

Biochemistry 2005 Jul;44(27):9472-85

Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA.

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http://dx.doi.org/10.1021/bi050295zDOI Listing
July 2005

The mechanism of target base attack in DNA cytosine carbon 5 methylation.

Biochemistry 2004 Sep;43(36):11460-73

Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA.

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http://dx.doi.org/10.1021/bi0496743DOI Listing
September 2004