Publications by authors named "Zaid H Maayah"

37Publications

Breast cancer diagnosis is associated with relative left ventricular hypertrophy and elevated endothelin-1 signaling.

BMC Cancer 2020 Aug 12;20(1):751. Epub 2020 Aug 12.

Cardiovascular Research Centre, Department of Pediatrics, Faculty of Medicine and Dentistry, 458 Heritage Medical Research Centre, University of Alberta, Edmonton, Alberta, T6G 2S2, Canada.

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http://dx.doi.org/10.1186/s12885-020-07217-1DOI Listing
August 2020

Empagliflozin suppresses inflammation and protects against acute septic renal injury.

Inflammopharmacology 2020 Jun 20. Epub 2020 Jun 20.

Cardiovascular Research Centre, Departments of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1007/s10787-020-00732-4DOI Listing
June 2020

Chronically Elevating Circulating Ketones Can Reduce Cardiac Inflammation and Blunt the Development of Heart Failure.

Circ Heart Fail 2020 Jun 4;13(6):e006573. Epub 2020 Jun 4.

Cardiovascular Research Centre (N.J.B., S.S., S.T., M.F., R.A.B., J.L.L., D.B., D.Y.V., M.A.S., A.S.A., Z.H.M., J.M.S., J.R.U., J.R.B.D.), University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.119.006573DOI Listing
June 2020

Fluconazole Represses Cytochrome P450 1B1 and Its Associated Arachidonic Acid Metabolites in the Heart and Protects Against Angiotensin II-Induced Cardiac Hypertrophy.

J Pharm Sci 2020 Jul 30;109(7):2321-2335. Epub 2020 Mar 30.

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada; Cardiovascular Research Centre, Faculty of Medicine and Dentistry University of Alberta, Edmonton, Alberta, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.xphs.2020.03.016DOI Listing
July 2020

The anti-inflammatory and analgesic effects of formulated full-spectrum cannabis extract in the treatment of neuropathic pain associated with multiple sclerosis.

Inflamm Res 2020 Jun 1;69(6):549-558. Epub 2020 Apr 1.

Cardiovascular Research Centre, Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.

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http://dx.doi.org/10.1007/s00011-020-01341-1DOI Listing
June 2020

The molecular mechanisms that underpin the biological benefits of full-spectrum cannabis extract in the treatment of neuropathic pain and inflammation.

Biochim Biophys Acta Mol Basis Dis 2020 Jul 19;1866(7):165771. Epub 2020 Mar 19.

Cardiovascular Research Centre, Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2020.165771DOI Listing
July 2020

Dietary-Induced Obesity, Hepatic Cytochrome P450, and Lidocaine Metabolism: Comparative Effects of High-Fat Diets in Mice and Rats and Reversibility of Effects With Normalization of Diet.

J Pharm Sci 2020 02 13;109(2):1199-1210. Epub 2019 Nov 13.

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.xphs.2019.11.007DOI Listing
February 2020

Role of Cytochrome p450 and Soluble Epoxide Hydrolase Enzymes and Their Associated Metabolites in the Pathogenesis of Diabetic Cardiomyopathy.

J Cardiovasc Pharmacol 2019 09;74(3):235-245

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1097/FJC.0000000000000707DOI Listing
September 2019

Resveratrol improves cardiac function and exercise performance in MI-induced heart failure through the inhibition of cardiotoxic HETE metabolites.

J Mol Cell Cardiol 2018 12 28;125:162-173. Epub 2018 Oct 28.

Cardiovascular Research Centre, Department of Pediatrics, Mazankowski Alberta Heart Institute, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00222828183072
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http://dx.doi.org/10.1016/j.yjmcc.2018.10.023DOI Listing
December 2018

Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects.

Toxicol Mech Methods 2019 Feb 18;29(2):119-127. Epub 2018 Dec 18.

d Department of Pharmaceutical Sciences , College of Pharmacy, Qatar University , Doha , Qatar.

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http://dx.doi.org/10.1080/15376516.2018.1528650DOI Listing
February 2019

Correction to: Mechanistically elucidating the in vitro safety and efficacy of a novel doxorubicin derivative.

Drug Deliv Transl Res 2018 10;8(5):1592

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, T6G 2R3, Canada.

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http://dx.doi.org/10.1007/s13346-018-0569-6DOI Listing
October 2018

2-Methoxyestradiol protects against pressure overload-induced left ventricular hypertrophy.

Sci Rep 2018 02 9;8(1):2780. Epub 2018 Feb 9.

Faculty of Pharmacy & Pharmaceutical Sciences, Katz Group-Rexall Centre for Pharmacy and Health Research, University of Alberta, Edmonton, T6G 2E1, Canada.

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http://dx.doi.org/10.1038/s41598-018-20613-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807528PMC
February 2018

The Role of Soluble Epoxide Hydrolase Enzyme on Daunorubicin-Mediated Cardiotoxicity.

Cardiovasc Toxicol 2018 06;18(3):268-283

Faculty of Pharmacy and Pharmaceutical Sciences, 2142 J Katz Group-Rexall Centre for Pharmacy and Health Research, University of Alberta, Edmonton, AB, T6G 2E1, Canada.

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http://link.springer.com/10.1007/s12012-017-9437-8
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http://dx.doi.org/10.1007/s12012-017-9437-8DOI Listing
June 2018

Inhibition of Mid-chain HETEs Protects Against Angiotensin II-induced Cardiac Hypertrophy.

J Cardiovasc Pharmacol 2017 Jul;70(1):16-24

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1097/FJC.0000000000000494DOI Listing
July 2017

The role of cytochrome P450 1B1 and its associated mid-chain hydroxyeicosatetraenoic acid metabolites in the development of cardiac hypertrophy induced by isoproterenol.

Mol Cell Biochem 2017 May 1;429(1-2):151-165. Epub 2017 Mar 1.

Faculty of Pharmacy & Pharmaceutical Sciences, 2142J Katz Group-Rexall Centre for Pharmacy and Health Research, University of Alberta, Edmonton, T6G 2E1, Canada.

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http://dx.doi.org/10.1007/s11010-017-2943-yDOI Listing
May 2017

Differential Effects of Sunitinib on the Expression Profiles of Xenobiotic-Metabolizing Enzymes and Transporters in Rat Liver and Kidneys.

Basic Clin Pharmacol Toxicol 2016 Aug 16;119(2):173-83. Epub 2016 Feb 16.

Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

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http://dx.doi.org/10.1111/bcpt.12555DOI Listing
August 2016

CYP1B1 inhibition attenuates doxorubicin-induced cardiotoxicity through a mid-chain HETEs-dependent mechanism.

Pharmacol Res 2016 Mar 6;105:28-43. Epub 2016 Jan 6.

Faculty of Pharmacy & Pharmaceutical Sciences, Katz Group-Rexall Centre for Pharmacy and Health Research, T6G 2E1, University of Alberta, Edmonton, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2015.12.016DOI Listing
March 2016

The role of mid-chain hydroxyeicosatetraenoic acids in the pathogenesis of hypertension and cardiac hypertrophy.

Arch Toxicol 2016 Jan 2;90(1):119-36. Epub 2015 Nov 2.

Faculty of Pharmacy and Pharmaceutical Sciences, 2142J Katz Group-Rexall Centre for Pharmacy and Health Research, University of Alberta, Edmonton, AB, T6G 2E1, Canada.

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http://dx.doi.org/10.1007/s00204-015-1620-8DOI Listing
January 2016

Early Changes in Cytochrome P450s and Their Associated Arachidonic Acid Metabolites Play a Crucial Role in the Initiation of Cardiac Hypertrophy Induced by Isoproterenol.

Drug Metab Dispos 2015 Aug 1;43(8):1254-66. Epub 2015 Jun 1.

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada

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http://dx.doi.org/10.1124/dmd.115.063776DOI Listing
August 2015

Metformin inhibits 7,12-dimethylbenz[a]anthracene-induced breast carcinogenesis and adduct formation in human breast cells by inhibiting the cytochrome P4501A1/aryl hydrocarbon receptor signaling pathway.

Toxicol Appl Pharmacol 2015 Apr 17;284(2):217-26. Epub 2015 Feb 17.

Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2015.02.007DOI Listing
April 2015

5-, 12- and 15-Hydroxyeicosatetraenoic acids induce cellular hypertrophy in the human ventricular cardiomyocyte, RL-14 cell line, through MAPK- and NF-κB-dependent mechanism.

Arch Toxicol 2016 Feb 20;90(2):359-73. Epub 2015 Jan 20.

Faculty of Pharmacy and Pharmaceutical Sciences, 2142J Katz Group-Rexall Centre for Pharmacy and Health Research, University of Alberta, Edmonton, AB, T6G 2E1, Canada.

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http://dx.doi.org/10.1007/s00204-014-1419-zDOI Listing
February 2016

Human fetal ventricular cardiomyocyte, RL-14 cell line, is a promising model to study drug metabolizing enzymes and their associated arachidonic acid metabolites.

J Pharmacol Toxicol Methods 2015 Jan-Feb;71:33-41. Epub 2014 Nov 29.

Faculty of Pharmacy & Pharmaceutical Sciences, University of Alberta, Edmonton, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.vascn.2014.11.005DOI Listing
April 2016

Mitogen-activated protein kinases pathways mediate the sunitinib-induced hypertrophy in rat cardiomyocyte H9c2 cells.

Cardiovasc Toxicol 2015 Jan;15(1):41-51

Department of Pharmacology and Toxicology, College of Pharmacology, King Saud University, P.O. Box 2457, Riyadh, 11451, Kingdom of Saudi Arabia,

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http://dx.doi.org/10.1007/s12012-014-9266-yDOI Listing
January 2015

Development of cardiac hypertrophy by sunitinib in vivo and in vitro rat cardiomyocytes is influenced by the aryl hydrocarbon receptor signaling pathway.

Arch Toxicol 2014 Mar 19;88(3):725-38. Epub 2013 Nov 19.

Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh, 11451, Saudi Arabia.

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http://link.springer.com/content/pdf/10.1007/s00204-013-1159
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http://link.springer.com/10.1007/s00204-013-1159-5
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http://dx.doi.org/10.1007/s00204-013-1159-5DOI Listing
March 2014

The role of aryl hydrocarbon receptor-regulated cytochrome P450 enzymes in glioma.

Curr Pharm Des 2013 ;19(40):7155-66

Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Kingdom of Saudi Arabia.

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http://dx.doi.org/10.2174/13816128113199990583DOI Listing
August 2014

Effect of long-term human exposure to environmental heavy metals on the expression of detoxification and DNA repair genes.

Environ Pollut 2013 Oct 17;181:226-32. Epub 2013 Jul 17.

Department of Pharmacology & Toxicology, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.

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http://dx.doi.org/10.1016/j.envpol.2013.06.014DOI Listing
October 2013

The role of aryl hydrocarbon receptor signaling pathway in cardiotoxicity of acute lead intoxication in vivo and in vitro rat model.

Toxicology 2013 Apr 5;306:40-9. Epub 2013 Feb 5.

Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

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http://dx.doi.org/10.1016/j.tox.2013.01.024DOI Listing
April 2013

Sunitinib, a tyrosine kinase inhibitor, induces cytochrome P450 1A1 gene in human breast cancer MCF7 cells through ligand-independent aryl hydrocarbon receptor activation.

Arch Toxicol 2013 May 4;87(5):847-56. Epub 2013 Jan 4.

Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 2529, Riyadh, 11461, Kingdom of Saudi Arabia.

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http://dx.doi.org/10.1007/s00204-012-0996-yDOI Listing
May 2013

Metformin rescues the myocardium from doxorubicin-induced energy starvation and mitochondrial damage in rats.

Oxid Med Cell Longev 2012 10;2012:434195. Epub 2012 May 10.

Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.

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http://dx.doi.org/10.1155/2012/434195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359722PMC
September 2012

Camel milk triggers apoptotic signaling pathways in human hepatoma HepG2 and breast cancer MCF7 cell lines through transcriptional mechanism.

J Biomed Biotechnol 2012 13;2012:593195. Epub 2012 May 13.

Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.

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http://dx.doi.org/10.1155/2012/593195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359759PMC
December 2012