Yingyao Zhou

Yingyao Zhou

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Yingyao Zhou

Publications by authors named "Yingyao Zhou"

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58Publications

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Metascape provides a biologist-oriented resource for the analysis of systems-level datasets.

Nat Commun 2019 04 3;10(1):1523. Epub 2019 Apr 3.

Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA, 92037, USA.

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http://dx.doi.org/10.1038/s41467-019-09234-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447622PMC
April 2019

Identification of a Xist silencing domain by Tiling CRISPR.

Sci Rep 2019 Feb 20;9(1):2408. Epub 2019 Feb 20.

Tumor Initiation and Maintenance Program, NCI-designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, 92037, USA.

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http://dx.doi.org/10.1038/s41598-018-36750-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382781PMC
February 2019

An Automatic Quality Control Pipeline for High-Throughput Screening Hit Identification.

J Biomol Screen 2016 Sep 16;21(8):832-41. Epub 2016 Jun 16.

Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA

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http://dx.doi.org/10.1177/1087057116654274DOI Listing
September 2016

High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission.

Cell Host Microbe 2016 Jan 31;19(1):114-26. Epub 2015 Dec 31.

Division of Pharmacology and Drug Discovery, Department of Pediatrics, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2015.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723716PMC
January 2016

Profiling the kinome for drug discovery.

Drug Discov Today Technol 2006 ;3(3):269-76

Kinase Drug Discovery, Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA. Electronic

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http://dx.doi.org/10.1016/j.ddtec.2006.09.012DOI Listing
July 2014

Chemical and biological properties of frequent screening hits.

J Chem Inf Model 2012 Apr 12;52(4):913-26. Epub 2012 Apr 12.

Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.

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http://dx.doi.org/10.1021/ci300005yDOI Listing
April 2012

In silico gene prioritization by integrating multiple data sources.

PLoS One 2011 24;6(6):e21137. Epub 2011 Jun 24.

Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0021137PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123338PMC
November 2011

Chemical-text hybrid search engines.

J Chem Inf Model 2010 Jan;50(1):47-54

Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, USA.

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http://dx.doi.org/10.1021/ci900380sDOI Listing
January 2010

Snapshot PK: a rapid rodent in vivo preclinical screening approach.

Drug Discov Today 2008 Apr 26;13(7-8):360-7. Epub 2007 Nov 26.

Department of Pharmacology, Genomics Institute of the Novartis Research Foundation (GNF), San Diego, CA, USA.

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http://dx.doi.org/10.1016/j.drudis.2007.10.014DOI Listing
April 2008

In silico discovery of transcription regulatory elements in Plasmodium falciparum.

BMC Genomics 2008 Feb 7;9:70. Epub 2008 Feb 7.

Department of Cell Biology, ICND 202, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1186/1471-2164-9-70DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268928PMC
February 2008

Exposure of Plasmodium sporozoites to the intracellular concentration of potassium enhances infectivity and reduces cell passage activity.

Mol Biochem Parasitol 2007 Nov 13;156(1):32-40. Epub 2007 Jul 13.

Michael Heidelberger Division of Immunology, Department of Pathology, New York University School of Medicine, New York, NY 10016, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016668510700207
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http://dx.doi.org/10.1016/j.molbiopara.2007.07.004DOI Listing
November 2007

Large-scale annotation of small-molecule libraries using public databases.

J Chem Inf Model 2007 Jul-Aug;47(4):1386-94. Epub 2007 Jul 3.

Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, USA.

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http://dx.doi.org/10.1021/ci700092vDOI Listing
October 2007

A probability-based approach for the analysis of large-scale RNAi screens.

Nat Methods 2007 Oct 9;4(10):847-9. Epub 2007 Sep 9.

The Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, California 92121, USA.

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http://dx.doi.org/10.1038/nmeth1089DOI Listing
October 2007

A role for IkappaB kinase 2 in bipolar spindle assembly.

Proc Natl Acad Sci U S A 2007 Oct 15;104(43):16940-5. Epub 2007 Oct 15.

Genomics Institute of the Novartis Research Foundation, 10675 John J. Hopkins Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1073/pnas.0706493104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040438PMC
October 2007

Identification of novel therapeutic targets for HIV infection through functional genomic cDNA screening.

Virology 2007 May 25;362(1):16-25. Epub 2007 Jan 25.

Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S004268220600896
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http://dx.doi.org/10.1016/j.virol.2006.11.036DOI Listing
May 2007

Study of gene function based on spatial co-expression in a high-resolution mouse brain atlas.

BMC Syst Biol 2007 Apr 16;1:19. Epub 2007 Apr 16.

Department of Computer Science, University of California, Riverside, 900 University Avenue, Riverside, CA 92521, USA.

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http://dx.doi.org/10.1186/1752-0509-1-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1863433PMC
April 2007

Learning from the data: mining of large high-throughput screening databases.

J Chem Inf Model 2006 Nov-Dec;46(6):2381-95

Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, USA.

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http://dx.doi.org/10.1021/ci060102uDOI Listing
February 2007

Novel statistical approach for primary high-throughput screening hit selection.

J Chem Inf Model 2005 Nov-Dec;45(6):1784-90

Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, USA.

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http://dx.doi.org/10.1021/ci0502808DOI Listing
June 2006

Haplotype-based quantitative trait mapping using a clustering algorithm.

BMC Bioinformatics 2006 May 18;7:258. Epub 2006 May 18.

Electrical Engineering and Computer Science Department, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1186/1471-2105-7-258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1533867PMC
May 2006

A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase.

Proc Natl Acad Sci U S A 2006 Mar 28;103(10):3775-80. Epub 2006 Feb 28.

Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1073/pnas.0600040103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1383649PMC
March 2006

The Plasmodium falciparum sexual development transcriptome: a microarray analysis using ontology-based pattern identification.

Mol Biochem Parasitol 2005 Sep;143(1):67-79

Department of Cell Biology ICND202, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.molbiopara.2005.05.007DOI Listing
September 2005

In silico gene function prediction using ontology-based pattern identification.

Bioinformatics 2005 Apr 5;21(7):1237-45. Epub 2004 Nov 5.

Genomics Institute of the Novartis Research Foundation San Diego, CA 92121, USA.

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http://dx.doi.org/10.1093/bioinformatics/bti111DOI Listing
April 2005

In vivo transcriptome of Plasmodium falciparum reveals overexpression of transcripts that encode surface proteins.

J Infect Dis 2005 Apr 28;191(7):1196-203. Epub 2005 Feb 28.

Department of Immunology and Infectious Disease, Harvard School of Public Health, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1086/428289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582152PMC
April 2005

In vivo transcriptional profiling of Plasmodium falciparum.

Malar J 2004 Aug 5;3:30. Epub 2004 Aug 5.

Department of Immunology and Infectious Disease, Harvard School of Public Health, Boston, Massachusetts 02115, USA.

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http://malariajournal.biomedcentral.com/articles/10.1186/147
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http://dx.doi.org/10.1186/1475-2875-3-30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC514566PMC
August 2004

Leveraging two-way probe-level block design for identifying differential gene expression with high-density oligonucleotide arrays.

BMC Bioinformatics 2004 Apr 20;5:42. Epub 2004 Apr 20.

Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, California 92121, USA.

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http://dx.doi.org/10.1186/1471-2105-5-42DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC411067PMC
April 2004

Match-only integral distribution (MOID) algorithm for high-density oligonucleotide array analysis.

BMC Bioinformatics 2002 22;3. Epub 2002 Jan 22.

Genomics Institute of the Novartis Research Foundation, 3115 Merryfield Row, San Diego, CA 92121, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC65509PMC
November 2003

Discovery of gene function by expression profiling of the malaria parasite life cycle.

Science 2003 Sep 31;301(5639):1503-8. Epub 2003 Jul 31.

Department of Cell Biology ICND202, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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https://pdfs.semanticscholar.org/1adf/c3394dbced2c6c35e60182
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http://dx.doi.org/10.1126/science.1087025DOI Listing
September 2003

Algorithms for high-density oligonucleotide array.

Curr Opin Drug Discov Devel 2003 May;6(3):339-45

Genomics Institute, Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA.

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May 2003

Genetic diversity in yeast assessed with whole-genome oligonucleotide arrays.

Genetics 2003 Jan;163(1):79-89

Genomics Institute of the Novartis Research Foundation, San Diego, California 92121, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462430PMC
January 2003

Excess polymorphisms in genes for membrane proteins in Plasmodium falciparum.

Science 2002 Oct;298(5591):216-8

Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1126/science.1075642DOI Listing
October 2002

Monitoring the chromosome 2 intraerythrocytic transcriptome of Plasmodium falciparum using oligonucleotide arrays.

Am J Trop Med Hyg 2002 Sep;67(3):233-43

Department of Cell Biology, The Scripps Research Institute, La Jolla, Calif 92037, USA.

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http://dx.doi.org/10.4269/ajtmh.2002.67.233DOI Listing
September 2002