Publications

Distinct effects of Hoxa2 overexpression in cranial neural crest populations reveal that the mammalian hyomandibular-ceratohyal boundary maps within the styloid process.
Dev Biol 2015 Jun 16;402(2):162-74. Epub 2015 Apr 16.
Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Chiyoda-ku, Tokyo 102-0076, Japan; Institute for Biology and Mathematics of Dynamical Cell Processes (iBMath), The University of Tokyo, 3-8-1 Komaba, Tokyo 153-8914, Japan. Electronic address:

Endothelin regulates neural crest deployment and fate to form great vessels through Dlx5/Dlx6-independent mechanisms.
Mech Dev 2013 Nov-Dec;130(11-12):553-66. Epub 2013 Aug 8.
Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Department of Pediatrics, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Preotic neural crest cells contribute to coronary artery smooth muscle involving endothelin signalling.
Nat Commun 2012 ;3:1267
Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Angiogenic morphogenesis driven by dynamic and heterogeneous collective endothelial cell movement.
Development 2011 Nov 28;138(21):4763-76. Epub 2011 Sep 28.
Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

Calpain-6, a microtubule-stabilizing protein, regulates Rac1 activity and cell motility through interaction with GEF-H1.
J Cell Sci 2011 Apr 15;124(Pt 8):1214-23. Epub 2011 Mar 15.
Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.


Endothelin receptor type A expression defines a distinct cardiac subdomain within the heart field and is later implicated in chamber myocardium formation.
Development 2010 Nov 7;137(22):3823-33. Epub 2010 Oct 7.
Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.



Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ.
Am J Physiol Renal Physiol 2008 Mar 2;294(3):F542-53. Epub 2008 Jan 2.
Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Recombinase-mediated cassette exchange reveals the selective use of Gq/G11-dependent and -independent endothelin 1/endothelin type A receptor signaling in pharyngeal arch development.
Development 2008 Feb 16;135(4):755-65. Epub 2008 Jan 16.
Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Regulation of gut-derived resistin-like molecule beta expression by nutrients.
Diabetes Res Clin Pract 2008 Jan 23;79(1):2-10. Epub 2007 Oct 23.
Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Maintenance of genomic methylation patterns during preimplantation development requires the somatic form of DNA methyltransferase 1.
Dev Biol 2008 Jan 30;313(1):335-46. Epub 2007 Oct 30.
Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.


The novel roles of liver for compensation of insulin resistance in human growth hormone transgenic rats.
Endocrinology 2006 Nov 17;147(11):5374-84. Epub 2006 Aug 17.
Department of Animal Sciences , Graduate School of Agriculture and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.

Role of hepatic AMPK activation in glucose metabolism and dexamethasone-induced regulation of AMPK expression.
Diabetes Res Clin Pract 2006 Aug 28;73(2):135-42. Epub 2006 Feb 28.
Department of Sports Medicine, Graduate School of Medicine, Nagoya University, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.


Glycogen debranching enzyme association with beta-subunit regulates AMP-activated protein kinase activity.
Am J Physiol Endocrinol Metab 2005 Sep 10;289(3):E474-81. Epub 2005 May 10.
Department of Internal Medicine, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.


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