Publications

One-step detection for two serological biomarker species to improve the diagnostic accuracy of hepatocellular carcinoma.
Talanta 2018 Feb 5;178:89-93. Epub 2017 Sep 5.
State Key Laboratory of Pharmaceutical Biotechnology and Collaborative Innovation Center of Chemistry for Life Sciences, Department of Biochemistry, Nanjing University, Nanjing 210093, PR China. Electronic address:

Novel and major QTL for branch angle detected by using DH population from an exotic introgression in rapeseed (Brassica napus L.).
Theor Appl Genet 2018 Jan 23;131(1):67-78. Epub 2017 Sep 23.
National Key Lab of Crop Genetic Improvement, National Center of Oil Crop Improvement (Wuhan), College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, 430070, People's Republic of China.

Comorbidity Burden of Dementia: A Hospital-Based Retrospective Study from 2003 to 2012 in Seven Cities in China.
Neurosci Bull 2017 Dec 13;33(6):703-710. Epub 2017 Nov 13.
Department of Neurology and Center for Clinical Neuroscience, Daping Hospital, Third Military Medical University, Chongqing, China.

Synergistic Chemopreventive and Therapeutic Effects of Co-drug UA-Met: Implication in Tumor Metastasis.
J Agric Food Chem 2017 Dec 11;65(50):10973-10983. Epub 2017 Dec 11.
Cancer Metastasis Alert and Prevention Center, Pharmaceutical Photocatalysis of State Key Laboratory of Photocatalysis on Energy and Environment, and Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy, College of Chemistry, Fuzhou University , Fuzhou 350116, China.

Helicobacter pylori VacA induces autophagic cell death in gastric epithelial cells via the endoplasmic reticulum stress pathway.
Cell Death Dis 2017 Dec 13;8(12):3207. Epub 2017 Dec 13.
Department of Clinical Microbiology and Immunology, Southwest Hospital and College of Medical Laboratory Science, Third Military Medical University, Chongqing, 400038, China.


Long non-coding RNA AFAP1-AS1 is a novel biomarker in various cancers: a systematic review and meta-analysis based on the literature and GEO datasets.
Oncotarget 2017 Nov 11;8(60):102346-102360. Epub 2017 Oct 11.
Key Laboratory of Carcinogenesis of Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, China.

Real-time activity assays of β-lactamases in living bacterial cells: application to the inhibition of antibiotic-resistant E. coli strains.
Mol Biosyst 2017 Oct;13(11):2323-2327
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Chemical Biology Innovation Lab, College of Chemistry and Materials Science, Northwest University, Xi'an 710127, P. R. China.

Endometriosis is the independent prognostic factor for survival in Chinese patients with epithelial ovarian carcinoma.
J Ovarian Res 2017 Oct 3;10(1):67. Epub 2017 Oct 3.
Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Shuaifuyuan 1, Wangfujing, Dongcheng District, Beijing, 100730, People's Republic of China.

Cross-Talk Between Insulin Signaling and G Protein-Coupled Receptors.
J Cardiovasc Pharmacol 2017 Aug;70(2):74-86
*Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; †The Key Laboratory for Drug Target Research and Pharmacodynamic Evaluation of Hubei Province, Wuhan, China; ‡Department of Pharmacology, University of California at Davis, Davis, CA; §VA Northern California Healthcare System, Mather, CA.

Toxic effects of glyphosate on diploid and triploid fin cell lines from Misgurnus anguillicaudatus.
Chemosphere 2017 Aug 25;180:356-364. Epub 2017 Mar 25.
Key Laboratory of Marine Bio-resource Restoration and Habitat Reparation in Liaoning Province, Dalian Ocean University, Dalian, Liaoning, China; Key Laboratory of Mariculture, Agriculture Ministry, PRC, Dalian Ocean University, Dalian, Liaoning, China.

Host Pore-Forming Protein Complex Neutralizes the Acidification of Endocytic Organelles to Counteract Intracellular Pathogens.
J Infect Dis 2017 Jun;215(11):1753-1763
Key Laboratory of Animal Models and Human Disease Mechanisms, Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan.

LISPRO mitigates β-amyloid and associated pathologies in Alzheimer's mice.
Cell Death Dis 2017 Jun 15;8(6):e2880. Epub 2017 Jun 15.
Rashid Laboratory for Developmental Neurobiology, Silver Child Development Center, Department of Psychiatry and Behavioral Neurosciences, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.


Carbamylmethyl Mercaptoacetate Thioether: A Novel Scaffold for the Development of L1 Metallo-β-lactamase Inhibitors.
ACS Med Chem Lett 2017 May 24;8(5):527-532. Epub 2017 Apr 24.
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Chemical Biology Innovation Laboratory, College of Chemistry and Materials Science, Northwest University, Xi'an 710127, P. R. China.


PLGA-PEG-PLGA triblock copolymeric micelles as oral drug delivery system: In vitro drug release and in vivo pharmacokinetics assessment.
J Colloid Interface Sci 2017 Mar 26;490:542-552. Epub 2016 Nov 26.
Cancer Metastasis Alert and Prevention Center, and Pharmaceutical Photocatalysis of State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou 350002, China. Electronic address:


Safety and efficacy of bleomycin/pingyangmycin-containing chemotherapy regimens for malignant germ cell tumor patients in the female genital system.
Oncotarget 2017 Feb;8(9):15952-15960
Department of Gynecology and Obstetrics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

[BM-MSCs from Wuzhishan mini-pigs delay the progress of renal fibrosis induced by chronic kidney disease through 
autocrine hepatocyte growth factor in vitro].
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2016 Dec;41(12):1260-1269
Department of Urology, Affiliated Haikou Hospital, Xiangya School of Medicine, Central South University, Haikou 570208, China.

A novel co-drug of aspirin and ursolic acid interrupts adhesion, invasion and migration of cancer cells to vascular endothelium via regulating EMT and EGFR-mediated signaling pathways: multiple targets for cancer metastasis prevention and treatment.
Oncotarget 2016 Nov;7(45):73114-73129
Cancer Metastasis Alert and Prevention Center, Pharmaceutical Photocatalysis of State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou, China.


Evaluation of the Tobacco Heating System 2.2 (THS2.2). Part 5: microRNA expression from a 90-day rat inhalation study indicates that exposure to THS2.2 aerosol causes reduced effects on lung tissue compared with cigarette smoke.
Regul Toxicol Pharmacol 2016 Nov 17;81 Suppl 2:S82-S92. Epub 2016 Nov 17.
Philip Morris International R&D, Part of Philip Morris International Group of Companies, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000, Neuchâtel, Switzerland.

Association of TCF7L2 and GCG Gene Variants with Insulin Secretion, Insulin Resistance, and Obesity in New-onset Diabetes.
Biomed Environ Sci 2016 Nov;29(11):814-817
Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou 450000, Henan, China; Department of Preventive Medicine, Shenzhen University; Shenzhen University Health Science Center, Shenzhen 518060, Guangdong, China.

Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure.
Circ Res 2016 Sep 30;119(8):931-43. Epub 2016 Aug 30.
From the Department of Pharmacology, University of California at Davis (F.B., B.X., G.R.R., T.W., Q.W., Q.F., M.L., Q.S., K.S.G., J.B., D.B., Y.K.X.); Department of Experimental Medicine (F.B., A.M.I.) and Department of Anatomical, Histological, Forensic, and Orthopedic Sciences (F.N.), Sapienza University of Rome, Italy; Department of Medicine and Epidemiology, School of Veterinary Medicine, and Surgical Research Facility, School of Medicine, University of California, Davis (W.F.); VA San Diego Healthcare System, La Jolla, CA (H.H.P.); Department of Anesthesiology, University of California, San Diego, La Jolla (H.H.P.); and VA Northern California Healthcare System, Mather (Y.K.X.).

RUNX2 mutation impairs bone remodelling of dental follicle cells and periodontal ligament cells in patients with cleidocranial dysplasia.
Mutagenesis 2016 11 10;31(6):677-685. Epub 2016 Aug 10.
Department of Preventive Dentistry, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, People's Republic of China,

Vacuolar Iron Transporter BnMEB2 Is Involved in Enhancing Iron Tolerance of Brassica napus.
Front Plant Sci 2016 13;7:1353. Epub 2016 Sep 13.
The Key Laboratory of Biology and Genetic Improvement of Oil Crops, The Ministry of Agriculture of PRC, Oil Crops Research Institute, Chinese Academy of Agriculture SciencesWuhan, China; Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei UniversityWuhan, China.

Correlation between Prenatal Exposure to Polybrominated Diphenyl Ethers (PBDEs) and Infant Birth Outcomes: A Meta-Analysis and an Experimental Study.
Int J Environ Res Public Health 2017 03 7;14(3). Epub 2017 Mar 7.
Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang 110001, China.

RNA m6A methylation regulates the ultraviolet-induced DNA damage response.
Nature 2017 03 15;543(7646):573-576. Epub 2017 Mar 15.
Division of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts 02115, USA.

Clinical characteristics and prognosis of ultra high-risk gestational trophoblastic neoplasia patients: A retrospective cohort study.
Gynecol Oncol 2017 07 29;146(1):81-86. Epub 2017 Apr 29.
Departments of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuaifuyuan, Wangfujing, Dongcheng District, 100730 Beijing, PR China. Electronic address:

Co-Activation of PKC-δ by CRIF1 Modulates Oxidative Stress in Bone Marrow Multipotent Mesenchymal Stromal Cells after Irradiation by Phosphorylating NRF2 Ser40.
Theranostics 2017 25;7(10):2634-2648. Epub 2017 Jun 25.
Department of Blood Transfusion, Radiation Biology Laboratory, The Second Affiliated Hospital, Third Military Medical University, Chongqing 400038, China.


Azolylthioacetamides as a potent scaffold for the development of metallo-β-lactamase inhibitors.
Bioorg Med Chem Lett 2017 12 20;27(23):5225-5229. Epub 2017 Oct 20.
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Innovation Laboratory of Chemical Biology, College of Chemistry and Materials Science, Northwest University, Xi'an 710127, PR China. Electronic address:

OF