Publications by authors named "Yang Liu"

14,596 Publications

  • Page 1 of 1

IFT20 governs mesenchymal stem cell fate through positively regulating TGF-β-Smad2/3-Glut1 signaling mediated glucose metabolism.

Redox Biol 2022 Jun 20;54:102373. Epub 2022 Jun 20.

Department of Basic & Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA; The Penn Center for Musculoskeletal Disorders, School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. Electronic address:

Aberrant lineage allocation of mesenchymal stem cells (MSCs) could cause bone marrow osteoblast-adipocyte imbalance, and glucose as an important nutrient is required for the maintenance of the MSCs' fate and function. Intraflagellar transport 20 (IFT20) is one of the IFT complex B protein which regulates osteoblast differentiation, and bone formation, but how IFT20 regulates MSCs' fate remains undefined. Here, we demonstrated that IFT20 controls MSC lineage allocation through regulating glucose metabolism during skeletal development. IFT20 deficiency in the early stage of MSCs caused significantly shortened limbs, decreased bone mass and significant increase in marrow fat. However, deletion of IFT20 in the later stage of MSCs and osteocytes just slightly decreased bone mass and bone growth and increased marrow fat. Additionally, we found that loss of IFT20 in MSCs promotes adipocyte formation, which enhances RANKL expression and bone resorption. Conversely, ablation of IFT20 in adipocytes reversed these phenotypes. Mechanistically, loss of IFT20 in MSCs significantly decreased glucose tolerance and suppressed glucose uptake and lactate and ATP production. Moreover, loss of IFT20 significantly decreased the activity of TGF-β-Smad2/3 signaling and reduced the binding activity of Smad2/3 to Glut1 promoter to downregulate Glut1 expression. These findings indicate that IFT20 plays essential roles for preventing MSC lineage allocation into adipocytes through TGF-β-Smad2/3-Glut1 axis.
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http://dx.doi.org/10.1016/j.redox.2022.102373DOI Listing
June 2022

Orrella daihaiensis sp. nov., a bacterium isolated from Daihai Lake in Inner Mongolia.

Arch Microbiol 2022 Jun 25;204(7):427. Epub 2022 Jun 25.

College of Life Science and Technology, Inner Mongolia Normal University, Hohhot, 010022, Inner Mongolia, China.

A novel aerobic, Gram-staining-negative, non-motile, short-rod-shaped strain, designated f23, was obtained from Daihai Lake, Inner Mongolia, Republic of China. 16S rRNA gene sequences analysis showed that f23 belongs to the genus Orrella and is most closely related to Orrella marina H-Z20 with 98.35% sequence similarity. The strain was oxidase positive, catalase positive and had well growth at pH 6.5-8.5, at temperature 28-40 °C and at 0-4.5% (w/v) NaCl. Colonies incubated at 37 °C on marine 2216 agar for 3 days were white, smooth, transparent, circular and less than 1.0 mm in diameter. The total genome size of f23 was 2,803,849 bp with a G + C content of 52.79%. The average nucleotide identity (ANI) and digital DNA-DNA hybridization (dDDH) values between strain f23 and O. marina H-Z20 were 69.62% and 20.5%, which both below the species delineation threshold. Chemotaxonomic analysis showed that C, cyclo-C, C, Sum Feature 3 (Cω7c and/or Cω6c) and Sum Feature 8 (Cω6c and Cω7c) as the major fatty acids, ubiquinone-8 as the major isoprenoid quinone, phosphatidylethanolamine as the major cellular polar lipids. Based on the polyphasic analysis, f23 represents a novel species within the genus Orrella, for which the name Orrella daihaiensis sp. nov. is proposed. The type strain is f23 (= CGMCC 1.18761 = KCTC 82425).
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http://dx.doi.org/10.1007/s00203-022-03056-9DOI Listing
June 2022

Special issue "The advance of solid tumor research in China": 68Ga-PSMA-11 PET/CT for evaluating primary and metastatic lesions in different histological subtypes of renal cell carcinoma.

Int J Cancer 2022 Jun 25. Epub 2022 Jun 25.

Department of Urology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road East, Guangzhou, People's Republic of China.

Conventional imaging examinations are not sensitive enough for the early detection of recurrent or metastatic lesions in renal cell carcinoma (RCC) patients. We aimed to explore the role of Ga- prostate specific membrane antigen (PSMA)-11 positron emission tomography (PET)/computed tomography (CT) in the detection of primary and metastatic lesions in such patients. We retrospectively analyzed 50 RCC patients who underwent Ga-PSMA-11 PET/CT from November 2017 to December 2020. We observed a higher median accuracy and tumor-to-background maximum standard uptake value (SUVmax) ratio (TBR) of Ga-PSMA-11 PET/CT in clear cell RCC (ccRCC; 96.57% and 6.00, respectively) than in non-clear cell RCC (ncRCC; 82.05% and 2.99, respectively). The accuracies in detecting lesions in the renal region, bone, lymph nodes, and lungs in ccRCC were 100.00%, 95.00%, 98.08%, and 75.00%, respectively, and those in the renal region, bone, and lymph nodes in ncRCC were 100.00%, 86.67%, and 36.36%, respectively. The median TBRs of the lesions from the above locations were 0.38, 10.96, 6.69, and 13.71, respectively, in ccRCC and 0.13, 4.02, and 0.73, respectively, in ncRCC. The PSMA score evaluated with immunohistochemistry was correlated with the SUVmax (P = 0.046) in RCC. Higher PSMA scores were observed in ccRCC than in ncRCC (P = 0.031). Ga-PSMA-11 PET/CT resulted in changes in clinical management in 12.9% (4/31) of cases because of the discovery of new metastases not detected with conventional imaging. These results indicate that Ga-PSMA-11 PET/CT is a promising method for the detection of metastatic lesions in ccRCC, especially for those in the bone and lymph nodes. This article is protected by copyright. All rights reserved.
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http://dx.doi.org/10.1002/ijc.34189DOI Listing
June 2022

Tectoridin exhibits anti-rheumatoid arthritis activity through the inhibition of the inflammatory response and the MAPK pathway in vivo and in vitro.

Arch Biochem Biophys 2022 Jun 22;727:109328. Epub 2022 Jun 22.

School of Pharmacy, Xi'an Jiaotong University, Xi'an, PR China. Electronic address:

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by inflammation infiltration of the synovial tissues and the fibroblast-like synoviocytes. Tectoridin is a botanical active ingredient with anti-inflammatory properties. In this study, the anti-arthritic effects of tectoridin and its mechanism of action are examined in TNF-α-induced human fibroblast-like synovial cells (HFLSs cells) and complete Freund's adjuvant (CFA)-stimulated arthritic mice. Arthritis progression was evaluated via bodyweight, hind paw swelling, organ index, and synovial pathology. IL-1β, IL-6 and other pro-inflammatory factors concentrations, and the expression of MAPK pathway proteins in HFLSs cells and arthritic mice were measured using ELISA and western blotting. Results showed that tectoridin significantly decreased the swelling of the paws and joints as well as the increased immune organ index within CFA-induced arthritic mice. Histopathological analysis showed that tectoridin alleviated the lesions of ankle joints and synovial tissues induced by CFA. Secretion of pro-inflammatory cytokines in TNF-α-induced HFLSs cells and CFA-stimulated arthritic mice were also abated by tectoridin. Similarly, the presence of tectoridin significantly inhibited the abnormal phosphorylation levels of ERK, JNK, and p38 in vivo and in vitro. All those results highlighted that tectoridin exhibits anti-arthritis effects by inhibiting MAPK-mediated inflammatory responses.
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http://dx.doi.org/10.1016/j.abb.2022.109328DOI Listing
June 2022

Scopariusicides D-M, ent-clerodane-based isomeric meroditerpenoids with a cyclobutane-fused γ/δ-lactone core from Isodon scoparius.

Bioorg Chem 2022 Jun 17;127:105973. Epub 2022 Jun 17.

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming 650201, Yunnan, China. Electronic address:

Scopariusicides D-M (1-10), ten new ent-clerodane-based meroditerpenoids with a cyclobutane-fused γ/δ-lactone core, were isolated from Isodon scoparius. Their structures were determined by comprehensive analysis of spectroscopic data, single-crystal X-ray diffraction, chemical transformation, and TDDFT ECD calculation. A plausible biosynthetic pathway of 1-10 was proposed in which the asymmetrical cyclobutane ring was formed via a crossed "head-to-tail" intermolecular [2 + 2] cycloaddition in anti/syn facial approaches between an ent-clerodane lactone and a cis-4-hydroxycinnamic acid. Bioactivity evaluation manifested that 5 exhibited significant neuroprotective effect against corticosterone-induced injury in PC12 cells, while 6 and 7 exhibited moderate immunosuppressive activity against human T cell proliferation stimulated by anti-CD3/anti-CD28 mAb.
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http://dx.doi.org/10.1016/j.bioorg.2022.105973DOI Listing
June 2022

Molecular Sieving of Propylene from Propane in Metal-Organic Framework-Derived Ultramicroporous Carbon Adsorbents.

ACS Appl Mater Interfaces 2022 Jun 24. Epub 2022 Jun 24.

Key Laboratory of Biomass Chemical Engineering of ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, 38 Zheda Road, Hangzhou 310027, P. R. China.

The development of adsorption-based separation processes alternative to the energy-intensive cryogenic distillation for a mixture of propylene and propane remains essential but challenging in gas industries. Molecular sieving separation of CH/CH on stable carbon adsorbents appeals to be promising, while it is quite challenging to realize due to the random distributions and arrangements of the internal pores in common carbons. Herein, a series of polysaccharide-based CD-MOF-derived ultramicroporous carbon adsorbents with their pore size tuned at a subangstrom level were prepared. Molecular sieving separation of CH/CH was realized on the optimal C-CDMOF-2-700 owing to the delicate structure with an appropriate pore size (5.0 Å). Besides, C-CDMOF-2-700 exhibited a high CH uptake of 1.97 mmol g under ambient conditions. An ultrahigh uptake ratio of CH/CH at 1.0 kPa (403) was also achieved, outperforming all reported adsorbents. Kinetic adsorption tests and breakthrough experiments further demonstrate this well-designed carbon adsorbent to be promising in industrial CH/CH separation.
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http://dx.doi.org/10.1021/acsami.2c09189DOI Listing
June 2022

Substantial non-growing season CO loss across Tibetan alpine permafrost region.

Glob Chang Biol 2022 Jun 24. Epub 2022 Jun 24.

State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China.

One of the major uncertainties for projecting permafrost carbon (C)-climate feedback is a poor representation of the non-growing season carbon dioxide (CO ) emissions under a changing climate. Here, combining in situ field observations, regional synthesis and a random forest model, we assessed contemporary and future soil respired CO (that is, soil respiration, Rs) across the Tibetan alpine permafrost region, which has received much less attention compared with the Arctic permafrost domain. We estimated the regional mean Rs of 229.8, 72.9 and 302.7 g C m year during growing season, non-growing season and the entire year, respectively; corresponding to the contemporary losses of 296.9, 94.3 and 391.2 Tg C year from this high-altitude permafrost-affected area. The non-growing season Rs accounted for a quarter of the annual soil CO efflux. Different from the prevailing view that temperature is the most limiting factor for cold-period CO release in Arctic permafrost ecosystems, precipitation determined the spatial pattern of non-growing season Rs on the Tibetan Plateau. Using the key predictors, model extrapolation demonstrated additional losses of 38.8 and 74.5 Tg C from the non-growing season for a moderate mitigation scenario and a business-as-usual emissions scenario, respectively. These results provide a baseline for non-growing season CO emissions from high-altitude permafrost areas and help for accurate projection of permafrost C-climate feedback.
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http://dx.doi.org/10.1111/gcb.16315DOI Listing
June 2022

Divergent Trajectory of Soil Autotrophic and Heterotrophic Respiration upon Permafrost Thaw.

Environ Sci Technol 2022 Jun 24. Epub 2022 Jun 24.

State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China.

Warming-induced permafrost thaw may stimulate soil respiration (Rs) and thus cause a positive feedback to climate warming. However, due to the limited in situ observations, it remains unclear about how Rs and its autotrophic (Ra) and heterotrophic (Rh) components change upon permafrost thaw. Here we monitored variations in Rs and its components along a permafrost thaw sequence on the Tibetan Plateau, and explored the potential linkage of Rs components (i.e., Ra and Rh) with biotic (e.g., plant functional traits and soil microbial diversity) and abiotic factors (e.g., substrate quality). We found that Ra and Rh exhibited divergent responses to permafrost collapse: Ra increased with the time of thawing, while Rh exhibited a hump-shaped pattern along the thaw sequence. We also observed different drivers of thaw-induced changes in the ratios of Ra:Rs and Rh:Rs. Except for soil water status, plant community structure, diversity, and root properties explained the variation in Ra:Rs ratio, soil substrate quality and microbial diversity were key factors associated with the dynamics of Rh:Rs ratio. Overall, these findings demonstrate divergent patterns and drivers of Rs components as permafrost thaw prolongs, which call for considerations in Earth system models for better forecasting permafrost carbon-climate feedback.
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http://dx.doi.org/10.1021/acs.est.1c07575DOI Listing
June 2022

The Interferon Gamma-Related Long Noncoding RNA Signature Predicts Prognosis and Indicates Immune Microenvironment Infiltration in Colon Adenocarcinoma.

Front Oncol 2022 7;12:876660. Epub 2022 Jun 7.

Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.

Colon adenocarcinoma (COAD) is one of the most common clinically malignant tumours of the digestive system, with high incidence and mortality and poor prognosis. Interferon-gamma (IFN-γ) and long noncoding RNAs (lncRNAs) have prognostic values and were closely associated with immune microenvironment in COAD. Thus, identifying IFN-γ-related lncRNAs may be valuable in predicting the survival of patients with COAD. In this study, we identified IFN-γ-related lncRNAs and divided COAD patients from the Cancer Genome Atlas (TCGA) database into training and validation sets. Pearson's correlation analysis and least absolute shrinkage and selection operator (LASSO) Cox regression were performed to select IFN-γ-related lncRNA-associated prognoses. Thirteen lncRNAs (AC025165.8, AC091633.3, FENDRR, LINC00882, LINC01828, LINC01829, MYOSLID, RP11-154H23.4, RP11-20J15.3, RP11-324L17.1, RP11-342A23.2, RP11-805I24.3, SERTAD4-AS1) were identified to construct an IFN-γ-related lncRNA prognostic signature in TCGA training (n =213) and validation (n =213) cohorts. COAD patient risk scores were calculated and classified into high- and low-risk groups based on the median value of the risk scores in each dataset. We compared the overall survival (OS) of patients stratified by age, gender, and stage. The OS in the high-risk group was significantly shorter than that in the low-risk group. In addition, the clinical nomogram incorporating the prognostic signature and clinical features showed a high concordance index of 0.78 and accurately predicted 1-, 3-, and 5-year survival times among COAD patients in the high- and low-risk groups. Based on the risk model, the high- and low-risk groups exhibited distinct differences in the immune system by gene set enrichment analysis (GSEA) functional annotation, and differentially expressed genes (DEGs) between the high- and low-risk groups were subjected to Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis. We investigated the expression of multiple immune checkpoint genes in the high- and low-risk groups and plotted Kaplan-Meier survival curves, indicating that immune checkpoint genes, such as LAG3 and PD. L1, STING and TIM 3, were also expressed differently between the two risk groups. Subsequently, there were dramatic differences in mutated genes, SNV (single nucleotide variants) classes, variant types and variant allele frequencies between low- and high-risk patients with COAD. Patients stratified by risk scores had different sensitivities to common chemotherapeutic agents. Finally, we used quantitative real-time polymerase chain reaction (qRT-PCR) assays to demonstrate that three lncRNAs were significantly differentially expressed in COAD tissues and adjacent normal tissues. Considered together, a thirteen-lncRNA prognostic signature has great potential to be a prognostic biomarker and could play an essential role in the immune microenvironment of COAD.
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http://dx.doi.org/10.3389/fonc.2022.876660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9211770PMC
June 2022

The Prognostic Significance of the and Gene in Adult Patients with Acute Myeloid Leukemia.

Indian J Hematol Blood Transfus 2022 Jul 5;38(3):481-491. Epub 2021 Aug 5.

Stem Cell Laboratory and Department of Hematology, Affiliated Hospital of Southwest Medical University, Sichuan Province, Luzhou City, China.

To investigate the expression and clinical significance of Bridging INtegrator 1 () and cyclin D2 () in newly diagnosed cytogenetically heterogenous adult acute myeloid leukemia patients. Real-time quantitative PCR (RQ-PCR) was used to detect the expression of and genes in 49 newly diagnosed adult patients with AML, and their clinical significance was analyzed. and genes are highly expressed in patients with AML, which suggest their potential as molecular markers. A statistical significant correlation was found between expression with bone marrow blasts ( = 0.012), CD34 expression ( = 0.026), NLR ( = 0.019) and Karyotype risk ( = 0.005). There was a statistically significant correlation between and age ( = 0.001), NLR ( = 0.046) Karyotype risk ( = 0.033). The expression level of was related to early treatment response (CR or not) ( = 0.043). expression was significantly correlated with overall survival ( = 0.013), but not with CR ( = 0.731). and genes are highly expressed in patients with AML, suggesting the potential of these two genes as molecular markers. Moreover, high levels of are associated with better prognosis, suggesting the possibility of these two genes as prognostic markers.
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http://dx.doi.org/10.1007/s12288-021-01479-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209615PMC
July 2022

Short-Term High-Fat Diet Fuels Colitis Progression in Mice Associated With Changes in Blood Metabolome and Intestinal Gene Expression.

Front Nutr 2022 7;9:899829. Epub 2022 Jun 7.

Health Sciences Institute, China Medical University, Shenyang, China.

Clinical cases and animal experiments show that high-fat (HF) diet is involved in inflammatory bowel disease (IBD), but the specific mechanism is not fully clear. A close association between long-term HF-induced obesity and IBD has been well-documented. However, there has been limited evaluation of the impact of short-term HF feeding on the risk of intestinal inflammation, particularly on the risk of disrupted metabolic homeostasis. In this study, we analyzed the metabolic profile and tested the vulnerability of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis after short-term HF feeding in mice. The results showed that compared with the control diet (CD), the fatty acid (FA), amino acid (AA), and bile acid (BA) metabolisms of mice in the HF group were significantly changed. HF-fed mice showed an increase in the content of saturated and unsaturated FAs and a decrease in the content of tryptophan (Trp). Furthermore, the disturbed spatial distribution of taurocholic acid (TCA) in the ileum and colon was identified in the HF group using matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI). After HF priming, mice on TNBS induction were subjected to more severe colonic ulceration and histological damage compared with their CD counterparts. In addition, TNBS enema induced higher gene expressions of mucosal pro-inflammatory cytokines under HF priming conditions. Overall, our results show that HF may promote colitis by disturbing lipid, AA, and BA metabolic homeostasis and inflammatory gene expressions.
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http://dx.doi.org/10.3389/fnut.2022.899829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209758PMC
June 2022

The Role of Toll-like Receptor Agonists and Their Nanomedicines for Tumor Immunotherapy.

Pharmaceutics 2022 Jun 10;14(6). Epub 2022 Jun 10.

Department of Pharmaceutics, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 Wenhuaxi Road, Jinan 250012, China.

Toll-like receptors (TLRs) are a class of pattern recognition receptors that play a critical role in innate and adaptive immunity. Toll-like receptor agonists (TLRa) as vaccine adjuvant candidates have become one of the recent research hotspots in the cancer immunomodulatory field. Nevertheless, numerous current systemic deliveries of TLRa are inappropriate for clinical adoption due to their low efficiency and systemic adverse reactions. TLRa-loaded nanoparticles are capable of ameliorating the risk of immune-related toxicity and of strengthening tumor suppression and eradication. Herein, we first briefly depict the patterns of TLRa, followed by the mechanism of agonists at those targets. Second, we summarize the emerging applications of TLRa-loaded nanomedicines as state-of-the-art strategies to advance cancer immunotherapy. Additionally, we outline perspectives related to the development of nanomedicine-based TLRa combined with other therapeutic modalities for malignancies immunotherapy.
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http://dx.doi.org/10.3390/pharmaceutics14061228DOI Listing
June 2022

The Association between Dietary Patterns and Pre-Pregnancy BMI with Gestational Weight Gain: The "Born in Shenyang" Cohort.

Nutrients 2022 Jun 20;14(12). Epub 2022 Jun 20.

Health Sciences Institute, China Medical University, Shenyang 110122, China.

The reported associations of maternal dietary patterns during pregnancy with gestational weight gain are inconsistent, especially among the less studied Asian Chinese populations. In a prospective pre-birth cohort study conducted in northern China, we determined the associations between maternal dietary patterns and the probability of excess gestational weight gain (EGWG) among 1026 pregnant women. We used 3-day food diaries to assess maternal diet and performed principal component analysis to identify dietary patterns. Maternal adherence to a traditional pattern, which was characterized by a higher intake of tubers, vegetables, fruits, red meat, and rice, was associated with a higher probability of EGWG (quartile 3 vs. quartile 1, odds ratio [OR] = 1.62, 95% confidence interval [CI] = 1.10-2.38). This risk association was more pronounced among women who were overweight/obese before pregnancy (quartile 4 vs. quartile 1, OR = 5.17, 95% CI = 1.45-18.46; for interaction < 0.01). Maternal adherence to a high protein pattern, which was characterized by a higher intake of fried foods, beans and bean products, dairy products, and fruits, was associated with a lower risk of EGWG (quartile 3 vs. quartile 1, OR = 0.56, 95% CI, 0.39-0.81). The protective association was more pronounced among non-overweight/obese women ( for interaction < 0.01). These findings may help to develop interventions and better define target populations for EGWG prevention.
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http://dx.doi.org/10.3390/nu14122551DOI Listing
June 2022

Effects of Substrate Roughness on Microstructure and Fatigue Behavior of Plasma Electrolytic Oxidation-Coated Ti-6Al-4V Alloy.

Materials (Basel) 2022 Jun 15;15(12). Epub 2022 Jun 15.

Key Laboratory for Anisotropy and Texture of Materials (Ministry of Education), School of Materials Science and Engineering, Northeastern University, Shenyang 110819, China.

Ceramic coatings were prepared by plasma electrolytic oxidation (PEO) on four different surface roughness' of Ti-6Al-4V alloys. The effects of substrate roughness on the microstructure and fatigue behavior were investigated. Microstructural characterization was carried out by scanning electron microscopy (SEM) and a laser scanning confocal microscope. In addition, an X-ray diffractometer (XRD) and a U-X360 stress meter were used to analyze the phase composition and residual stress properties of the coatings. The microstructure of coatings revealed the growth mechanism of the coatings. The larger and deeper grooves of the substrate promoted the nucleation and growth of the PEO coating, but the defects (cracks and pores) of the oxide layer became more serious. The fatigue test indicated a significant influence of substrate roughness on the fatigue life under low cyclic stress. The fatigue damage of PEO coatings decreases as the surface roughness of substrates decreases because of the synergistic effect of the coating surface defects and coating/substrate interface roughness. Substrate roughness influences the quality and fatigue performance of the oxide layer.
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http://dx.doi.org/10.3390/ma15124256DOI Listing
June 2022

Mechanical and Thermal Properties of Phosphoric Acid Activated Geopolymer Materials Reinforced with Mullite Fibers.

Materials (Basel) 2022 Jun 13;15(12). Epub 2022 Jun 13.

The Future Lab, Tsinghua University, Beijing 100084, China.

This article investigates several important properties, such as thermal resistance, mechanical properties, and phase evolution, of geopolymer ceramics reinforced with mullite fibers. This particular fiber reinforcing geopolymer composites was prepared from kaolinite and mullite fibers with phosphoric acid as activator. X-ray diffraction (XRD), thermogravimetry and differential scanning calorimetry, Fourier-transform infrared spectroscopy, and scanning electron microscopy were used to determine the phase evolution and strengthening mechanisms. With the addition of mullite fibers, the mechanical properties increased by at least 20%. The optimum flexural strength exceeded 13 MPa. It was found that mullite fibers had desirable interface bonding with this type of geopolymer, promoting both crack deflection and fiber pullout strengthening mechanisms. This was correlated with a significant strengthening effect of the fibers. The linear shrinkage after heat treatment at 1150 °C~1550 °C was investigated and correlated with XRD analyses. The addition of mullite fibers reduced the linear shrinkage significantly up to 1350 °C. The large linear shrinkage above 1450 °C was correlated with the decomposition and melting of the AlPO phase.
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http://dx.doi.org/10.3390/ma15124185DOI Listing
June 2022

Multi-Scale Mixed Attention Network for CT and MRI Image Fusion.

Entropy (Basel) 2022 Jun 19;24(6). Epub 2022 Jun 19.

College of Electronics and Information Engineering, Sichuan University, Chengdu 610064, China.

Recently, the rapid development of the Internet of Things has contributed to the generation of telemedicine. However, online diagnoses by doctors require the analyses of multiple multi-modal medical images, which are inconvenient and inefficient. Multi-modal medical image fusion is proposed to solve this problem. Due to its outstanding feature extraction and representation capabilities, convolutional neural networks (CNNs) have been widely used in medical image fusion. However, most existing CNN-based medical image fusion methods calculate their weight maps by a simple weighted average strategy, which weakens the quality of fused images due to the effect of inessential information. In this paper, we propose a CNN-based CT and MRI image fusion method (MMAN), which adopts a visual saliency-based strategy to preserve more useful information. Firstly, a multi-scale mixed attention block is designed to extract features. This block can gather more helpful information and refine the extracted features both in the channel and spatial levels. Then, a visual saliency-based fusion strategy is used to fuse the feature maps. Finally, the fused image can be obtained via reconstruction blocks. The experimental results of our method preserve more textual details, clearer edge information and higher contrast when compared to other state-of-the-art methods.
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http://dx.doi.org/10.3390/e24060843DOI Listing
June 2022

A Time Two-Mesh Compact Difference Method for the One-Dimensional Nonlinear Schrödinger Equation.

Entropy (Basel) 2022 Jun 9;24(6). Epub 2022 Jun 9.

School of Mathematical Sciences, Inner Mongolia University, Hohhot 010021, China.

The nonlinear Schrödinger equation is an important model equation in the study of quantum states of physical systems. To improve the computing efficiency, a fast algorithm based on the time two-mesh high-order compact difference scheme for solving the nonlinear Schrödinger equation is studied. The fourth-order compact difference scheme is used to approximate the spatial derivatives and the time two-mesh method is designed for efficiently solving the resulting nonlinear system. Comparing to the existing time two-mesh algorithm, the novelty of the new algorithm is that the fine mesh solution, which becomes available, is also used as the initial guess of the linear system, which can improve the calculation accuracy of fine mesh solutions. Compared to the two-grid finite element methods (or finite difference methods) for nonlinear Schrödinger equations, the numerical calculation of this method is relatively simple, and its two-mesh algorithm is implemented in the temporal direction. Taking advantage of the discrete energy, the result with O(τC4+τF2+h4) in the discrete L2-norm is obtained. Here, τC and τF are the temporal parameters on the coarse and fine mesh, respectively, and is the space step size. Finally, some numerical experiments are conducted to demonstrate its efficiency and accuracy. The numerical results show that the new algorithm gives highly accurate results and preserves conservation laws of charge and energy. Furthermore, by comparing with the standard nonlinear implicit compact difference scheme, it can reduce the CPU time without loss of accuracy.
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http://dx.doi.org/10.3390/e24060806DOI Listing
June 2022

A Mutation in Endogenous saRNA miR-23a Influences Granulosa Cells Response to Oxidative Stress.

Antioxidants (Basel) 2022 Jun 15;11(6). Epub 2022 Jun 15.

College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.

Phenotypes are the result of the interaction between the gene and the environment, so the response of individuals with different genotypes to an environment is variable. Here, we reported that a mutation in miR-23a influences granulosa cells (GCs) response to oxidative stress, a common mechanism of environmental factors affecting female reproduction. We showed that nuclear miR-23a is a pro-apoptotic miRNA in porcine GCs through the activation of the transcription and function of , a long non-coding RNA (lncRNA) induces GC apoptosis and responses to oxidative stress. Mechanistically, miR-23a acts as an endogenous small activating RNA (saRNA) to alter histone modifications of the promoter through the direct binding to its core promoter. A C > T mutation was identified at -398 nt of the miR-23a core promoter, which created a novel binding site for the transcription factor SMAD4 and recruited the transcription repressor SMAD4 to inhibit miR-23a transcription and function in GCs. Notably, g.-398C > T mutation in the miR-23a promoter reduced GCs response to oxidative stress. In addition, g.-398C > T mutation was significantly associated with sow fertility traits. In short, our findings preliminarily revealed the genetic basis of individual differences in the response to oxidative stress from the perspective of a single mutation and identified miR-23a as a candidate gene for the environmental adaptation to oxidative stress.
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http://dx.doi.org/10.3390/antiox11061174DOI Listing
June 2022

Vanadium recovery by electrodialysis using polymer inclusion membranes.

J Hazard Mater 2022 Aug 8;436:129315. Epub 2022 Jun 8.

College of Environment and Safety Engineering, Qingdao University of Science and Technology, 53 Zhengzhou Road, Qingdao 266042, China.

Industrial applications and environmental awareness recently prompted vanadium recovery spell from secondary resources. In this work, a polymer inclusion membrane containing trioctylmethylammonium chloride as carrier was successfully employed in electrodialysis for vanadium recovery from acidic sulfate solutions. The permeability coefficient of V(V) increased from 0.29 µm·s (without electric field) to 4.10 µm·s (with the 20 mA·cm current density) The transport performance of VOSO, which was the predominant species containing V(V) in the acidic region (pH <3), was influenced by the aqueous pH value and sulfate concentration. Under an electric field, a low concentrated HSO solution (0.2 M) effectively stripped V(V) from the membranes, avoiding the requirement of a highly concentrated HSO without electric field. Under the optimum conditions, the permeability coefficient and flux reached 6.80 µm·s and 13.34 µmol·m·s, respectively. High selectivity was observed for the separation of V(V) and Mo(VI) from mixed solutions of Co (II), Ni (II), Mn (II), and Al (III). Additionally, the separation between Mo(VI) and V(V) was further improved by adjusting the acidity of the stripping solution. The V(V) selectivity for the resulting membrane was higher than that of commercial anion exchange membranes.
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http://dx.doi.org/10.1016/j.jhazmat.2022.129315DOI Listing
August 2022

The multiple biotoxicity integrated study in grass carp (Ctenopharyngodon idella) caused by Ochratoxin A: Oxidative damage, apoptosis and immunosuppression.

J Hazard Mater 2022 Aug 2;436:129268. Epub 2022 Jun 2.

Animal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, Sichuan, China; Fish Nutrition and Safety Production University Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu 611130, Sichuan, China; Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Sichuan 611130, China. Electronic address:

Ochratoxin A (OTA) is a common hazardous food contaminant that seriously endangers human and animal health. However, limited study is focused on aquatic animal. This research investigated the multiple biotoxicity of OTA on spleen (SP) and head kidney (HK) in grass carp and its related mechanism. Our data showed that, dietary supplemented with OTA above 1209 μg/kg caused histopathological damages by decreasing the number of lymphocytes and necrotizing renal parenchymal cells. Meanwhile, OTA caused oxidative damage and reduced the isoforms mRNAs transcripts of antioxidant enzymes (e.g., GPX1, GPX4, GSTO) partly due to suppressing NF-E2-related factor 2 (Nrf2). OTA triggered apoptosis through mitochondria and death receptor pathway potentially by p38 mitogen-activated protein kinase (p38MAPK) activation. Besides, OTA exacerbated inflammation by down-regulation of anti-inflammatory factor (e.g., IL-10, IL-4) and up-regulations of pro-inflammatory factors (e.g., TNF-α, IL-6), which could be ascribed to signaling meditation of Janus kinase / signal transducer and activator of transcription (JAK/STAT). Additionally, the safe upper limits of OTA were estimated to be 677.6 and 695.08 μg/kg based on the immune-related indexes (C3 contents in the SP and LZ activities in the HK, respectively). Our study has provided a wide insight for toxicological assessment of feed pollutant in aquatic animals.
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http://dx.doi.org/10.1016/j.jhazmat.2022.129268DOI Listing
August 2022

Water durability modification of cerium-manganese oxide by tin shell for efficient airborne benzene oxidation.

J Hazard Mater 2022 Aug 26;436:129207. Epub 2022 May 26.

Key Laboratory of Industrial Ecology and Environmental Engineering (Ministry of Education), School of Ocean Science and Technology, Dalian University of Technology, Panjin 124221, China.

Single or cooperative incorporation of Ce and Sn elements into α-MnO parent were tried to update the catalytic benzene oxidation performance, and the successive modification via Ce doping and Sn deposition was demonstrated to be a promising methodology to offer high mineralization and avoid moisture-aroused inactivation. Ce doping caused lattice distortion, increased Mn content to 2.7 times that of the pristine MnO and weakened Mn-O bonds due to electron transfer from Ce to lattice oxygen, thus facilizing oxygen vacancy formation. Further, Sn deposition on CeMn substrate induced strong metal support interaction (SMSI) due to the core-shell like structure of [email protected], which promoted the construction of active oxygen vacancies to an even larger extent (1.2 and 2.5 times that of the CeMn and pristine MnO, respectively). The thus-formed larger amount of reactive oxygen species rendered the [email protected] simultaneously with high CO yield and low CO production. Also benefited from the SMSI effect, the [email protected]'s ability to continuously activate O and HO into reactive oxygen species (e.g.,·OH radicals) was enhanced, which could offset the negativity caused by water vapor, thereby keeping > 95% removal during 5.5 h water switch on/off investigation at 200 °C. Reaction pathways were uncovered with designed experimentations.
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http://dx.doi.org/10.1016/j.jhazmat.2022.129207DOI Listing
August 2022

Enhancing the resistance to HS toxicity during anaerobic digestion of low-strength wastewater through granular activated carbon (GAC) addition.

J Hazard Mater 2022 05 11;430:128473. Epub 2022 Feb 11.

Department of Civil and Environmental Engineering, University of Alberta, Edmonton, Alberta T6G 1H9, Canada. Electronic address:

Low-strength wastewater was treated using two laboratory-scale up-flow anaerobic sludge blankets (UASB) for 130 days under sulfate-reducing conditions. Granular activated carbon (GAC) was added to one of the reactors. The GAC addition increased the total chemical oxygen demand removal by 21-28% and total methane production by 32-78%. The sludge from the GAC-amended UASB showed higher specific methanogenic activities (SMA) and higher activities in the presence of HS, indicating that the GAC addition enhanced the resistance of methanogens to HS toxicity. Further, the microbial communities showed that the GAC addition shifted microbial communities. A robust syntrophic partnership between bacteria (i.e., Bacteroidetes_vadinHA17 and Trichococcus) and methanogens was established in the GAC-amended UASB. Sulfate-reducing bacteria (SRB) were enriched in the GAC biofilm, indicating the coexistence of competition and cooperation between SRB and methanogens. These findings provide significant insights regarding microbial community dynamics, especially SRB and methanogens, in a GAC-amended anaerobic digestion process under sulfate-reducing conditions.
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http://dx.doi.org/10.1016/j.jhazmat.2022.128473DOI Listing
May 2022

Resveratrol protects against ox-LDL-induced endothelial dysfunction in atherosclerosis via depending on circ_0091822/miR-106b-5p-mediated upregulation of TLR4.

Immunopharmacol Immunotoxicol 2022 Jun 23:1-25. Epub 2022 Jun 23.

Department of Cardiovascular Medicine, The Second Affiliated Hospital, Hengyang Medcial School, University of South China, Hengyang City, Hunan, 421001, China.

Background: Atherosclerosis (AS) is the most common inducer of cardiovascular diseases, and resveratrol (RSV) has played protective function in endothelial injury of AS. This study was to explore the molecular mechanism of RSV in oxidized low-density lipoprotein (ox-LDL)-mediated endothelial dysfunction.

Methods: Circ_0091822, microRNA-106b-5p (miR-106b-5p) or toll-like receptor (TLR4) levels were examined using reverse transcription-quantitative polymerase chain reaction assay. Cell viability was detected via Cell Counting Kit-8 assay and angiogenesis was assessed by tube formation assay. Cell apoptosis was determined through flow cytometry. The protein analysis was conducted via western blot. Inflammatory cytokines were measured by enzyme-linked immunosorbent assay. Oxidative injury was evaluated using the commercial kits. The binding detection was performed via dual-luciferase reporter assay and RNA pull-down assay.

Results: Circ_0091822 was downregulated by RSV in ox-LDL-treated endothelial cells. RSV promoted cell viability and angiogenesis while inhibited apoptosis, inflammation and oxidative stress after exposure to ox-LDL. The circ_0091822 knockdown relieved the ox-LDL-induced cell damages. RSV suppressed the ox-LDL-caused endothelial dysfunction via inducing the downregulation of circ_0091822. Circ_0091822 could target miR-106b-5p, and the reversal of circ_0091822 for RSV function was achieved by sponging miR-106b-5p. Circ_0091822 absorbed miR-106b-5p to elevate the level of TLR4. RSV impeded ox-LDL-induced damages by regulating miR-106b-5p/TLR4 axis.

Conclusion: All these findings suggested that RSV acted as an inhibitory factor in ox-LDL-induced endothelial injury via downregulating circ_0091822 to upregulate miR-106b-5p-related TLR4.
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http://dx.doi.org/10.1080/08923973.2022.2093740DOI Listing
June 2022

Composition Engineering of Amorphous Nickel Boride Nanoarchitectures Enabling Highly Efficient Electrosynthesis of Hydrogen Peroxide.

Adv Mater 2022 Jun 23:e2202995. Epub 2022 Jun 23.

Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, 215123, P. R. China.

Developing advanced electrocatalysts with exceptional two electron (2e ) selectivity, activity and stability are crucial for driving oxygen reduction reaction (ORR) to produce hydrogen peroxide (H O ). Herein, a composition engineering strategy has been adapted to flexibly regulate the intrinsic activity of amorphous nickel boride nanoarchitectures for efficient 2e ORR by oriented reduction of Ni with different amounts of BH . Among borides, the amorphous NiB delivers the 2e selectivity close to 99% at 0.4 V and over 93% in a wide potential range, together with a negligible activity decay under prolonged time. Notably, an ultrahigh H O production rate of 4.753 mol g h has been achieved upon assembling NiB in the practical gas diffusion electrode. The combination of X-ray absorption and in situ Raman spectroscopy, as well as transient photovoltage measurements with density functional theory unequivocally reveal that the atomic ratio between Ni and B induces the local electronic structure diversity, allowing optimization of the adsorption energy of Ni towards *OOH and reducing the interfacial charge transfer kinetics to inhibit the formation of O-O. This article is protected by copyright. All rights reserved.
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http://dx.doi.org/10.1002/adma.202202995DOI Listing
June 2022

Non-covalent reconfigurable microgel colloidosomes with a well-defined bilayer shell.

Chem Sci 2022 Jun 26;13(21):6205-6216. Epub 2022 Apr 26.

Department of Chemistry, The Chinese University of Hong Kong Shatin N. T. Hong Kong China

Microgels are extremely interfacially active and are widely used to stabilize emulsions. However, they are commonly used to stabilize oil-in-water emulsions due to their intrinsic hydrophilicity and initially dispersed in water. In addition, there have been no attempts to control microgel structural layers that are formed at the interface and as a result it limits applications of microgel in advanced materials. Here, we show that by introducing octanol into poly(-isopropylacrylamide--methacrylic acid) (PNIPAM--MAA) microgels, octanol-swollen microgels can rapidly diffuse from the initially dispersed oil phase onto the water droplet surface. This facilitates the formation of microgel-laden interfacial layers with strong elastic responses and also generates stable inverse water-in-oil Pickering emulsions. These emulsions can be used as templates to produce microgel colloidosomes, herein termed 'microgelsomes', with shells that can be fine-tuned from a particle monolayer to a well-defined bilayer. The microgelsomes can then be used to encapsulate and/or anchor nanoparticles, proteins, vitamin C, bio-based nanocrystals or enzymes. Moreover, the programmed release of these substances can be achieved by using ethanol as a trigger to mediate shell permeability. Thus, these reconfigurable microgelsomes with a microgel-bilayer shell can respond to external stimuli and demonstrate tailored properties, which offers novel insights into microgels and promise wider application of Pickering emulsions stabilized by soft colloids.
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http://dx.doi.org/10.1039/d2sc01082hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159095PMC
June 2022

StATL2-like could affect growth and cold tolerance of plant by interacting with StCBFs.

Plant Cell Rep 2022 Jun 23. Epub 2022 Jun 23.

College of Life Science, State Key Laboratory of Crop Biology, Shandong Key Laboratory of Crop Biology, Shandong Agricultural University, Taian, 271018, China.

Key Message: Our results confirmed that StATL2-like could interact with StCBFs and regulate plant growth. Meanwhile, StATL2-like acted as a negative regulator on low-temperature tolerance in plants. As important transcription factors for resisting many kinds of stresses, C-repeat-binding factors (CBF) play a key role in plant low-temperature tolerance by increasing COR genes expressions. Here, we report that StATL2-like, a RING-H2 E3 ubiquitin in Solanum tuberosum L., interacted with StCBF1 and StCBF4, respectively. AtATL2 is a highly homologous gene of StATL2-like in Arabidopsis thaliana. Under normal conditions, atl2 Arabidopsis mutant showed a growth inhibition phenotype while overexpressed StATL2-like in wild type Arabidopsis and atl2 mutant promoted plant growth. Besides, atl2 mutant had better low-temperature tolerance compared with wild type and StATL2-like transgenic lines which demonstrated that StATL2-like acted as a negatively regulator on low-temperature tolerance in plant. Moreover, atl2 mutant improved the scavenging capacity of reactive oxygen species (ROS) and alleviate the damage of photosynthetic system II (PSII) compared with StATL2-like transgenic lines under cold conditions. These results suggested a new component in CBF-dependent pathway to regulate plant growth and response to low-temperature stress in potato plants.
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http://dx.doi.org/10.1007/s00299-022-02890-xDOI Listing
June 2022

Bergamottin, a bioactive component of bergamot, inhibits SARS-CoV-2 infection in golden Syrian hamsters.

Antiviral Res 2022 Jun 19;204:105365. Epub 2022 Jun 19.

State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China; University of the Chinese Academy of Sciences, Beijing, 100049, China. Electronic address:

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused an ongoing pandemic, coronavirus disease-2019 (COVID-19), which has become a major global public health event. Antiviral compounds remain the predominant means of treating COVID-19. Here, we reported that bergamottin, a furanocoumarin originally found in bergamot, exhibited inhibitory activity against SARS-CoV-2 in vitro, ex vivo, and in vivo. Bergamottin interfered with multiple stages of virus life cycles, specifically blocking the SARS-CoV-2 spike-mediated membrane fusion and effectively reducing viral RNA synthesis. Oral delivery of bergamottin to golden Syrian hamsters at dosages of both 50 mg/kg and 75 mg/kg reduced the SARS-CoV-2 load in nasal turbinates and lung tissues. Pathological damage caused by viral infection was also ameliorated after bergamottin treatment. Overall, our study provides evidence of bergamottin as a promising natural compound, with broad-spectrum anti-coronavirus activity, that could be further developed in the fight against COVID-19 infection during the current pandemic.
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http://dx.doi.org/10.1016/j.antiviral.2022.105365DOI Listing
June 2022

Understanding Fishermen's Willingness and Preferences for Eco-compensation of Lake Conservation Projects: A Case Study From Nansi Lake Nature Reserve, China.

Environ Manage 2022 Jun 22. Epub 2022 Jun 22.

Zhangqiu Meteorological Bureau, Jinan, 250200, Shandong Province, China.

Lake regions face a tradeoff between water environmental conservation and social development. Although lake conservation projects along with eco-compensation policies are considered the solutions to this problem, it is often controversial and unsustainable. Therefore, it is essential to understand the key stakeholders' willingness to participate in lake conservation projects under the different compensation schemes. In this work, we conducted a choice experiment to estimate fishermen's willingness and preference for the returning fishponds to lake (RFTL) project in the Nansi Lake Nature Reserve (NLNR). Socioeconomic, perception and spatial factors are employed to analyze the preference heterogeneity of fishermen. We employed conditional logit, mixed logit and latent class models to estimates the parameters of factor variables considering the heterogeneous preferences and choice randomness across respondents. The results indicate that on average, fishermen are unwilling to change the status quo and are most concerned about the subsidy amount and contract duration in compensation contracts. However, there is obvious spatial heterogeneity in fishermen's choice preference, mainly manifested in their habitation distance to a town and fishpond location in different zones of the NLNR. Specifically, perceptions of supply and demand for water yield and water quality services significantly influence fishermen's choice, but they have opposite effects. Moreover, we estimated marginal willingness to accept (MWTA) of attributes in compensation contract and measured compensating surplus (CS) to compare different eco-compensation policy scenarios. Our results contribute to designing targeted payment policies, and promote the effective implementation of lake conservation projects and regional sustainable development.
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http://dx.doi.org/10.1007/s00267-022-01672-1DOI Listing
June 2022

Lactobacillus plantarum supplementation alleviates liver and intestinal injury in parenteral nutrition-fed piglets.

JPEN J Parenter Enteral Nutr 2022 Jun 22. Epub 2022 Jun 22.

Division of Pediatric Gastroenterology and Nutrition, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Objective: Long-term parenteral nutrition (PN) causes parenteral nutrition-associated liver disease (PNALD) for which therapeutic approaches are limited. This study aimed to investigate the effects of Lactobacillus plantarum CGMCC 1258 (LP) on liver and intestinal injury in the PN-fed neonatal piglets.

Methods: The piglets received PN with or without oral LP for 14 days. The levels of liver enzymes and inflammatory markers were measured using biochemical kits and q-RT-PCR. Serum fibroblast growth factor 19 (FGF19) was detected using an enzyme-linked immunosorbent assay (ELISA). The bile acid profiles in the liver, serum, and intestinal contents were determined using ultraperformance liquid chromatography coupled with mass spectrometry (UPLC-MS). The composition of intestinal bacteria was analyzed with 16S rRNA gene amplicon sequencing.

Results: LP supplementation was associated with improved markers of liver disease, inflammation, and oxidative stress in PN-fed piglets. Moreover, markers of intestinal injury and inflammation were alleviated by LP in PN-fed piglets. Mechanistically, LP increased the abundance of Lactobacillus in ileal contents and stimulated FGF19 expression in ileal mucosa. Subsequently, it increased the expression of small heterodimer partner (SHP) and inhibited cholesterol 7α-hydroxylase (CYP7A1) expression in the liver. Additionally, LP altered the systemic composition and metabolism of bile acids.

Conclusions: LP alleviated liver and intestinal injury in PN-fed neonatal piglets by altering the composition of intestinal bacteria and bile acids. This article is protected by copyright. All rights reserved.
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http://dx.doi.org/10.1002/jpen.2429DOI Listing
June 2022

[Responses of soil moisture at different slope positions to rainfall in dry-hot valley].

Ying Yong Sheng Tai Xue Bao 2022 May;33(5):1352-1362

School of Geography and Environmental Sciences, Guizhou Normal University, Guiyang 550025, China.

The study of short-term dynamics of soil moisture in the dry-hot valley area during rainfall process will help identify soil hydrological function. In this study, we analyzed the short-term responses of soil moisture to rainfall in Huajiang dry-hot valley of Guizhou, using monitoring method to yield high-frequency soil moisture monitoring data of different slope positions. The results showed that, during the whole monitoring period, soil moisture at each layer was at a moderate variation level (15.2%≤coefficient of variation CV≤29.7%), for both upper slope and middle slope. The fluctuation range of soil moisture of the upper slope (CV=21.1%) was greater than that of the middle slope (CV=19.1%), and that of the 0-5 cm soil layer (CV=26.2%) was greater than 20-40 cm layer (CV=16.5%). Compared with the middle slope, soil moisture of the upper slope had a faster response to rainfall. The supplement amount of rainfall was bigger and the supplement speed of rainfall was faster at the upper slope than that at the middle slope. The difference between the supplement speed and the depletion speed of soil moisture of the upper slope (2.3%·h) was greater than that of the middle slope (1.8%·h). With the increase of soil depth, the responses of soil moisture to rainfall in subsoil layer was earlier or synchronous with that in topsoil layer. When the supplement amount of soil moisture decreased and the supplement speed slowed down, the depletion speed slowed down. Compared with the middle slope, soil at the upper slope had greater water infiltration capacity and better water retention capacity. The responses of soil moisture to rainfall in dry-hot valley were influenced by micro-environment and microclimate, and the rapid recharge of dominant flow at rock-soil interface accelerated the response speed of subsoil moisture to rainfall, which made the slopes in this area easier to form mixed runoff generation mechanism.
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http://dx.doi.org/10.13287/j.1001-9332.202202.018DOI Listing
May 2022
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