Xianyong Yin

Xianyong Yin

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Xianyong Yin

Publications by authors named "Xianyong Yin"

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43Publications

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NFKB1 mediates Th1/Th17 activation in the pathogenesis of psoriasis.

Cell Immunol 2018 09 2;331:16-21. Epub 2018 May 2.

Institute of Dermatology and Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, No. 81 Meishan Road, Hefei, Anhui 230032, China; Key Laboratory of Dermatology, Anhui Medical University, Ministry of Education, Hefei, Anhui 230032, China. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2018.04.016DOI Listing
September 2018

A catalog of potential putative functional variants in psoriasis genome-wide association regions.

PLoS One 2018 1;13(5):e0196635. Epub 2018 May 1.

Institute of Dermatology, Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei, Anhui, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196635PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929547PMC
July 2018

Genotype imputation for Han Chinese population using Haplotype Reference Consortium as reference.

Hum Genet 2018 Jul 31;137(6-7):431-436. Epub 2018 May 31.

Institute of Dermatology and Department of Dermatology, First Affiliated Hospital, Anhui Medical University, Hefei, 81 Meishan Road, Hefei, 230032, Anhui, China.

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http://dx.doi.org/10.1007/s00439-018-1894-zDOI Listing
July 2018

Bach2 regulates aberrant activation of B cell in systemic lupus erythematosus and can be negatively regulated by BCR-ABL/PI3K.

Exp Cell Res 2018 04 6;365(1):138-144. Epub 2018 Mar 6.

Institute of Dermatology and Department of Dermatology, the First Affiliated Hospital, Anhui Medical University, No. 81 Meishan Road, Hefei, Anhui 230032, China; Key Laboratory of Dermatology, Anhui Medical University, Ministry of Education, Hefei, Anhui 230032, China. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2018.02.034DOI Listing
April 2018

Genome-wide meta-analysis identifies a novel susceptibility signal at CACNA2D3 for nicotine dependence.

Am J Med Genet B Neuropsychiatr Genet 2017 Jul 25;174(5):557-567. Epub 2017 Apr 25.

Department of Genetics and Renaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1002/ajmg.b.32540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656555PMC
July 2017

Epigenome-wide association data implicates DNA methylation-mediated genetic risk in psoriasis.

Clin Epigenetics 2016 5;8:131. Epub 2016 Dec 5.

Institute and Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Meishan Road 81, Hefei, 230032 Anhui Province China.

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http://dx.doi.org/10.1186/s13148-016-0297-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139011PMC
April 2017

Integration of expression quantitative trait loci and pleiotropy identifies a novel psoriasis susceptibility gene, PTPN1.

J Gene Med 2017 Jan;19(1-2)

Institute of Dermatology and Department of Dermatology, First Affiliated Hospital, Anhui Medical University, Anhui, China.

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http://dx.doi.org/10.1002/jgm.2939DOI Listing
January 2017

Common susceptibility variants are shared between schizophrenia and psoriasis in the Han Chinese population.

J Psychiatry Neurosci 2016 10;41(6):413-421

From the Institute of Dermatology, Department of Dermatology of The First Affiliated Hospital. Key lab of Dermatology Ministry of Education, Anhui Medical University, Hefei, China (Yin, Jiang, Wu, Cui, Shen, Cheng, Zhou, Chen, Zuo, Zhend, Fan, Wang, Sun, Yang, Zhang); the Institute of Dermatology, Huashan Hospital, Fudan University, Shanghai, China (Yin, Zhang, Huang, Xu, Zhang); the The Scripps Translational Science Institute, La Jolla, California, USA (Yin, Wineinger, Schork); the Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, USA (Yin, Schork); Human Biology, J. Craig Venter Institute, La Jolla, California, USA (Yin, Schork); the Department of Genetics, and Renaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, USA (Yin); the Scripps Health, La Jolla, California, USA (Wineinger); the Department of Neurology, the First Affiliated Hospital of Anhui Medical University, Hefei, China (Wang); the Peking University Sixth Hospital, Peking University Institute of Mental Health; Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China (Yue, Wang); the Peking University Sixth Hospital, Peking University Institute of Mental Health; Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China (Yue, Wang); the Human Genetics, Genome Institute of Singapore, Singapore (Norgren, Wang, Liu); the Institute of Mental Health, Singapore (Norgren, Wang, Liu); the Institute of Mental Health, Singapore (Lee); the Saw Swee Hock School of Public Health, National University of Singapore, Singapore 138672, Singapore (Tai, Liu).

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http://dx.doi.org/10.1503/jpn.150210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082512PMC
October 2016

A rare variant in COL11A1 is strongly associated with adult height in Chinese Han population.

J Genet Genomics 2016 09 4;43(9):549-554. Epub 2016 Apr 4.

Institute and Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei 230032, China; The Key Laboratory of Dermatology, Ministry of Education, Anhui Medical University, Hefei 230032, China; Collaborative Innovation Center for Complex and Severe Dermatosis, Anhui Medical University, Hefei 230032, China. Electronic address:

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http://dx.doi.org/10.1016/j.jgg.2016.04.002DOI Listing
September 2016

Identification of cell types, tissues and pathways affected by risk loci in psoriasis.

Mol Genet Genomics 2016 Apr 12;291(2):1005-12. Epub 2015 Nov 12.

Institute of Dermatology, Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei, 230032, Anhui, China.

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http://dx.doi.org/10.1007/s00438-015-1141-4DOI Listing
April 2016

Epigenome-Wide Association Analysis Identified Nine Skin DNA Methylation Loci for Psoriasis.

J Invest Dermatol 2016 Apr 29;136(4):779-787. Epub 2015 Dec 29.

Institute of Dermatology and Department of Dermatology, No. 1 Hospital, Anhui Medical University, Hefei, Anhui, China; Key Laboratory of Dermatology, Anhui Medical University, Ministry of Education, China, Hefei, Anhui, China; Department of Dermatology, Huashan Hospital of Fudan University, Shanghai, China; Department of Dermatology and Venereology, Anhui Medical University, Hefei, Anhui, China. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2015.12.029DOI Listing
April 2016

A weighted polygenic risk score using 14 known susceptibility variants to estimate risk and age onset of psoriasis in Han Chinese.

PLoS One 2015 1;10(5):e0125369. Epub 2015 May 1.

Institute of Dermatology, Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei, Anhui Province, China; Key lab of Dermatology, Ministry of Education, State Key Lab of Dermatology Incubation Center, Anhui Medical University, Hefei, Anhui Province, China; Key Lab of Gene Resource Utilization for Complex Diseases, Hefei, Anhui Province, China; Collaborative Innovation Center for Complex and Severe Dermatosis, Anhui Medical University, Hefei, Anhui Province, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125369PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416725PMC
February 2016

Genetic Susceptibility to Vitiligo: GWAS Approaches for Identifying Vitiligo Susceptibility Genes and Loci.

Front Genet 2016 1;7. Epub 2016 Feb 1.

Institute and Department of Dermatology, The First Affiliated Hospital, Anhui Medical UniversityHefei, China; Department of Dermatology, The Second Affiliated Hospital, Anhui Medical UniversityHefei, China.

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http://dx.doi.org/10.3389/fgene.2016.00003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740779PMC
February 2016

More heritability probably captured by psoriasis genome-wide association study in Han Chinese.

Gene 2015 Nov 11;573(1):46-9. Epub 2015 Jul 11.

Institute of Dermatology, Department of Dermatology, First Affiliated Hospital, Anhui Medical University, Hefei City, Anhui 230032, China; Key Lab of Dermatology (Anhui Medical University), Ministry of Education, Hefei City, Anhui 230032, China; Key Lab of Gene Resource Utilization for Complex Diseases, Hefei City, Anhui 230032, China; Collaborative Innovation Center for Complex and Severe Dermatosis, Anhui Medical University, Hefei City, Anhui 230032, China.

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http://dx.doi.org/10.1016/j.gene.2015.07.029DOI Listing
November 2015

Four genetic variants interact to confer susceptibility to atopic dermatitis in Chinese Han population.

Mol Genet Genomics 2015 Aug 25;290(4):1493-8. Epub 2015 Feb 25.

Institute and Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, 81 Meishan Road, Hefei, 230032, Anhui, China.

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http://dx.doi.org/10.1007/s00438-015-1014-xDOI Listing
August 2015

Introduction of the Institute of Dermatology, Anhui Medical University.

J Investig Dermatol Symp Proc 2015 Jul;17(1)

The Institute of Dermatology and Department of Dermatology, First Affiliated Hospital, Anhui Medical University, Hefei City, China.

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http://dx.doi.org/10.1038/jidsymp.2015.3DOI Listing
July 2015

The Contribution of Meta-Analysis of Genome-Wide Association Studies in Investigating the Genetic Susceptibility to Lupus.

J Investig Dermatol Symp Proc 2015 Jul;17(1):51-2

1] Institute of Dermatology and Department of Dermatology at No. 1 Hospital, Anhui Medical University, Hefei, China [2] Department of Dermatology and Venereology, Anhui Medical University, Hefei, China [3] Key Laboratory of Dermatology, Anhui Medical University, Ministry of Education, Hefei, China.

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http://dx.doi.org/10.1038/jidsymp.2015.25DOI Listing
July 2015

Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis.

Nat Commun 2015 04 9;6:6793. Epub 2015 Apr 9.

1] Institute of Dermatology and Department of Dermatology, No. 1 Hospital, Anhui Medical University, Hefei, Anhui 230022, China [2] Department of Dermatology, Huashan Hospital, Fudan University, Shanghai 200040, China [3] Department of Dermatology, No.2 Hospital, Anhui Medical University, Hefei, Anhui 230022, China [4] Collaborative Innovation Center of Complex and Severe Skin Disease, Anhui Medical University, Hefei, Anhui 230032, China [5] State Key Lab Incubation of Dermatology, Ministry of Science and Technology, Hefei, Anhui 230032, China [6] Key Lab of Dermatology, Ministry of Education, Hefei, Anhui 230032, China [7] Key Lab of Gene Resources Utilization for Severe Inherited Disorders, Anhui 230032, China.

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http://dx.doi.org/10.1038/ncomms7793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403312PMC
April 2015

Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.

Nat Commun 2015 Apr 23;6:6916. Epub 2015 Apr 23.

1] State Key Laboratory Incubation Base of Dermatology, Ministry of National Science and Technology, Anhui Medical University, Hefei, Anhui 230032, China [2] Key Lab of Dermatology (Anhui Medical University), Ministry of Education, Hefei, Anhui 230032, China [3] Collaborative Innovation Center for Complex and Severe Skin Diseases, Anhui Medical University, Hefei, Anhui 230032, China [4] Department of Human Genetics, Genome Institute of Singapore, A*STAR, Singapore 138672, Singapore [5] Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore, 138672, Singapore [6] School of Life Sciences, Anhui Medical University, Hefei, Anhui 230032, China.

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http://dx.doi.org/10.1038/ncomms7916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423213PMC
April 2015

Association of the late cornified envelope-3 genes with psoriasis and psoriatic arthritis: a systematic review.

J Genet Genomics 2015 Feb 10;42(2):49-56. Epub 2015 Jan 10.

Institute and Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei 230032, China; The Key Laboratory of Dermatology, Ministry of Education, Anhui Medical University, Hefei 230032, China; Collaborative Innovation Center for Complex and Severe Dermatosis, Anhui Province, Hefei 230032, China; Department of Dermatology, The Second Affiliated Hospital, Anhui Medical University, Hefei 230601, China. Electronic address:

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http://dx.doi.org/10.1016/j.jgg.2015.01.001DOI Listing
February 2015

Five regulatory genes detected by matching signatures of eQTL and GWAS in psoriasis.

J Dermatol Sci 2014 Nov 13;76(2):139-42. Epub 2014 Aug 13.

Institute of Dermatology, Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei, Anhui Province 230032, China; Key Lab of Dermatology, Ministry of Education, State Key Lab of Dermatology Incubation Center, Anhui Medical University, Hefei, Anhui Province 230032, China; Key Lab of Gene Resource Utilization for Complex Diseases, Hefei, Anhui Province 230032, China; Collaborative Innovation Center for Complex and Severe Dermatosis, Anhui Medical University, Hefei, Anhui Province 230032, China.

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http://dx.doi.org/10.1016/j.jdermsci.2014.07.007DOI Listing
November 2014

Exome sequencing identifies SLC17A9 pathogenic gene in two Chinese pedigrees with disseminated superficial actinic porokeratosis.

J Med Genet 2014 Oct 1;51(10):699-704. Epub 2014 Sep 1.

Institute of Dermatology and Department of Dermatology at No.1 Hospital, Anhui Medical University, Hefei, Anhui, China Department of Dermatology, Huashan Hospital of Fudan University, Shanghai, China Department of Dermatology at No.2 Hospital, Anhui Medical University, Hefei, Anhui, China Department of Dermatology and Venereology, Anhui Medical University, Hefei, Anhui, China State Key Laboratory Incubation Base of Dermatology, Ministry of National Science and Technology & Key Laboratory of Dermatology, Ministry of Education & Key Laboratory of Dermatology, Hefei, Anhui, China.

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http://jmg.bmj.com/lookup/doi/10.1136/jmedgenet-2014-102486
Publisher Site
http://dx.doi.org/10.1136/jmedgenet-2014-102486DOI Listing
October 2014

Combined effect of five single nucleotide polymorphisms related to IL23/Th17 pathway in the risk of psoriasis.

Immunogenetics 2014 Mar 14;66(3):215-8. Epub 2014 Jan 14.

Institute of Dermatology, Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei, Anhui, 230032, China,

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http://dx.doi.org/10.1007/s00251-013-0756-zDOI Listing
March 2014

Common variants explain a large fraction of the variability in the liability to psoriasis in a Han Chinese population.

BMC Genomics 2014 Jan 30;15:87. Epub 2014 Jan 30.

Institute of Dermatology, Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei, Anhui Province 230032, China.

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http://dx.doi.org/10.1186/1471-2164-15-87DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909441PMC
January 2014

Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

Am J Hum Genet 2013 Jan 27;92(1):41-51. Epub 2012 Dec 27.

Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong.

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http://dx.doi.org/10.1016/j.ajhg.2012.11.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542470PMC
January 2013

Confirmation of C4 gene copy number variation and the association with systemic lupus erythematosus in Chinese Han population.

Rheumatol Int 2012 Oct 9;32(10):3047-53. Epub 2011 Sep 9.

Institute of Dermatology and Department of Dermatology at No. 1 Hospital, Anhui Medical University, 81 Meishan Road, Hefei, Anhui, People's Republic of China.

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http://dx.doi.org/10.1007/s00296-011-2023-7DOI Listing
October 2012

Meta-analysis of NOD2/CARD15 polymorphisms with psoriasis and psoriatic arthritis.

Rheumatol Int 2012 Jul 30;32(7):1893-900. Epub 2011 Mar 30.

Institute of Dermatology and Department of Dermatology at No. 1 Hospital, Anhui Medical University, No. 81, Meishan Road, 230032 Hefei, Anhui, People's Republic of China.

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http://dx.doi.org/10.1007/s00296-011-1813-2DOI Listing
July 2012

Down-regulated expression of IKZF1 mRNA in peripheral blood mononuclear cells from patients with systemic lupus erythematosus.

Rheumatol Int 2011 Jun 1;31(6):819-22. Epub 2010 Aug 1.

Institute of Dermatology and Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Meishan Road, 230032, Hefei, Anhui, China.

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http://dx.doi.org/10.1007/s00296-010-1576-1DOI Listing
June 2011

Platelet-derived growth factor receptor alpha gene mutations in vitiligo vulgaris.

Acta Derm Venereol 2010 Mar;90(2):131-5

Institute of Dermatology and Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei, China.

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http://dx.doi.org/10.2340/00015555-0820DOI Listing
March 2010

Genomic dissection of population substructure of Han Chinese and its implication in association studies.

Am J Hum Genet 2009 Dec;85(6):762-74

Chinese Academy of Sciences and Max Planck Society Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, PR China.

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http://dx.doi.org/10.1016/j.ajhg.2009.10.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790582PMC
December 2009