Wilko Weichert

Wilko Weichert

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Wilko Weichert

Wilko Weichert

Publications by authors named "Wilko Weichert"

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Conceptual framework for precision cancer medicine in Germany: Consensus statement of the Deutsche Krebshilfe working group 'Molecular Diagnostics and Therapy'.

Eur J Cancer 2020 Aug 7;135:1-7. Epub 2020 Jun 7.

University Comprehensive Cancer Center Hamburg, Department of Oncology, Hematology with Section Bone Marrow Transplantation and Pneumology, University Medical Center Hamburg-Eppendorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2020.04.019DOI Listing
August 2020

Integrative Analysis of Multi-omics Data Identified EGFR and PTGS2 as Key Nodes in a Gene Regulatory Network Related to Immune Phenotypes in Head and Neck Cancer.

Clin Cancer Res 2020 Jul 11;26(14):3616-3628. Epub 2020 Mar 11.

Department of Otorhinolaryngology, Head and Neck Surgery, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-3997DOI Listing
July 2020

Adaptive ERK signalling activation in response to therapy and in silico prognostic evaluation of EGFR-MAPK in HNSCC.

Br J Cancer 2020 Jul 19;123(2):288-297. Epub 2020 May 19.

Department of Otorhinolaryngology, Head and Neck Surgery, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41416-020-0892-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7374086PMC
July 2020

Pancreatic neuroendocrine tumors with somatostatin expression and paraganglioma-like features.

Hum Pathol 2020 Jul 12. Epub 2020 Jul 12.

Department of Pathology, Technical University of Munich, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2020.07.004DOI Listing
July 2020

Integrated clinicomolecular characterization identifies RAS activation and CDKN2A deletion as independent adverse prognostic factors in cancer of unknown primary.

Int J Cancer 2020 Jun 11;146(11):3053-3064. Epub 2020 Mar 11.

Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ) and Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.32882DOI Listing
June 2020

New Pancreatic Cancer Biomarkers eIF1, eIF2D, eIF3C and eIF6 Play a Major Role in Translational Control in Ductal Adenocarcinoma.

Anticancer Res 2020 Jun;40(6):3109-3118

Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria

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http://dx.doi.org/10.21873/anticanres.14292DOI Listing
June 2020

Distinct immune evasion in APOBEC-enriched, HPV-negative HNSCC.

Int J Cancer 2020 May 29. Epub 2020 May 29.

Department of Hematology and Oncology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Hindenburgdamm 30, Berlin, 12203, Germany.

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http://dx.doi.org/10.1002/ijc.33123DOI Listing
May 2020

Quantifying potential confounders of panel-based tumor mutational burden (TMB) measurement.

Lung Cancer 2020 Apr 1;142:114-119. Epub 2020 Feb 1.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany; German Cancer Consortium (DKTK), Partner Site Heidelberg, Heidelberg, Germany; German Center for Lung Research (DZL), Translational Lung Research Center Heidelberg (TLRC-H), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2020.01.019DOI Listing
April 2020

Combined DCE-MRI- and FDG-PET enable histopathological grading prediction in a rat model of hepatocellular carcinoma.

Eur J Radiol 2020 Mar 23;124:108848. Epub 2020 Jan 23.

Institute for Diagnostic and Interventional Radiology, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Straße 22, D-81675 München, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejrad.2020.108848DOI Listing
March 2020

Risk stratification in luminal-type breast cancer: Comparison of Ki-67 with EndoPredict test results.

Breast 2020 Feb 12;49:101-107. Epub 2019 Nov 12.

Department of Obstetrics and Gynecology, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.1016/j.breast.2019.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375593PMC
February 2020

Clinicopathological Profiling of Lung Carcinoids with a Ki67 Index > 20.

Neuroendocrinology 2019 28;108(2):109-120. Epub 2018 Nov 28.

Department of Pathology, Technical University Munich, Munich, Germany.

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http://dx.doi.org/10.1159/000495806DOI Listing
December 2019

Lymph node infiltration, parallel metastasis and treatment success in breast cancer.

Breast 2019 Dec 5;48:1-6. Epub 2019 Aug 5.

Munich Cancer Registry, Institute for Medical Information Processing, Biometry and Epidemiology (IBE), Ludwig-Maximilians-University (LMU), D-81377, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.breast.2019.07.008DOI Listing
December 2019

A machine learning model for the prediction of survival and tumor subtype in pancreatic ductal adenocarcinoma from preoperative diffusion-weighted imaging.

Eur Radiol Exp 2019 10 17;3(1):41. Epub 2019 Oct 17.

Department of Diagnostic and Interventional Radiology, Faculty of Medicine, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22, DE-81675, Munich, Germany.

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http://dx.doi.org/10.1186/s41747-019-0119-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797674PMC
October 2019

Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification.

Authors:
Michael T Parsons Emma Tudini Hongyan Li Eric Hahnen Barbara Wappenschmidt Lidia Feliubadaló Cora M Aalfs Simona Agata Kristiina Aittomäki Elisa Alducci María Concepción Alonso-Cerezo Norbert Arnold Bernd Auber Rachel Austin Jacopo Azzollini Judith Balmaña Elena Barbieri Claus R Bartram Ana Blanco Britta Blümcke Sandra Bonache Bernardo Bonanni Åke Borg Beatrice Bortesi Joan Brunet Carla Bruzzone Karolin Bucksch Giulia Cagnoli Trinidad Caldés Almuth Caliebe Maria A Caligo Mariarosaria Calvello Gabriele L Capone Sandrine M Caputo Ileana Carnevali Estela Carrasco Virginie Caux-Moncoutier Pietro Cavalli Giulia Cini Edward M Clarke Paola Concolino Elisa J Cops Laura Cortesi Fergus J Couch Esther Darder Miguel de la Hoya Michael Dean Irmgard Debatin Jesús Del Valle Capucine Delnatte Nicolas Derive Orland Diez Nina Ditsch Susan M Domchek Véronique Dutrannoy Diana M Eccles Hans Ehrencrona Ute Enders D Gareth Evans Chantal Farra Ulrike Faust Ute Felbor Irene Feroce Miriam Fine William D Foulkes Henrique C R Galvao Gaetana Gambino Andrea Gehrig Francesca Gensini Anne-Marie Gerdes Aldo Germani Jutta Giesecke Viviana Gismondi Carolina Gómez Encarna B Gómez Garcia Sara González Elia Grau Sabine Grill Eva Gross Aliana Guerrieri-Gonzaga Marine Guillaud-Bataille Sara Gutiérrez-Enríquez Thomas Haaf Karl Hackmann Thomas V O Hansen Marion Harris Jan Hauke Tilman Heinrich Heide Hellebrand Karen N Herold Ellen Honisch Judit Horvath Claude Houdayer Verena Hübbel Silvia Iglesias Angel Izquierdo Paul A James Linda A M Janssen Udo Jeschke Silke Kaulfuß Katharina Keupp Marion Kiechle Alexandra Kölbl Sophie Krieger Torben A Kruse Anders Kvist Fiona Lalloo Mirjam Larsen Vanessa L Lattimore Charlotte Lautrup Susanne Ledig Elena Leinert Alexandra L Lewis Joanna Lim Markus Loeffler Adrià López-Fernández Emanuela Lucci-Cordisco Nicolai Maass Siranoush Manoukian Monica Marabelli Laura Matricardi Alfons Meindl Rodrigo D Michelli Setareh Moghadasi Alejandro Moles-Fernández Marco Montagna Gemma Montalban Alvaro N Monteiro Eva Montes Luigi Mori Lidia Moserle Clemens R Müller Christoph Mundhenke Nadia Naldi Katherine L Nathanson Matilde Navarro Heli Nevanlinna Cassandra B Nichols Dieter Niederacher Henriette R Nielsen Kai-Ren Ong Nicholas Pachter Edenir I Palmero Laura Papi Inge Sokilde Pedersen Bernard Peissel Pedro Perez-Segura Katharina Pfeifer Marta Pineda Esther Pohl-Rescigno Nicola K Poplawski Berardino Porfirio Anne S Quante Juliane Ramser Rui M Reis Françoise Revillion Kerstin Rhiem Barbara Riboli Julia Ritter Daniela Rivera Paula Rofes Andreas Rump Monica Salinas Ana María Sánchez de Abajo Gunnar Schmidt Ulrike Schoenwiese Jochen Seggewiß Ares Solanes Doris Steinemann Mathias Stiller Dominique Stoppa-Lyonnet Kelly J Sullivan Rachel Susman Christian Sutter Sean V Tavtigian Soo H Teo Alex Teulé Mads Thomassen Maria Grazia Tibiletti Marc Tischkowitz Silvia Tognazzo Amanda E Toland Eva Tornero Therese Törngren Sara Torres-Esquius Angela Toss Alison H Trainer Katherine M Tucker Christi J van Asperen Marion T van Mackelenbergh Liliana Varesco Gardenia Vargas-Parra Raymonda Varon Ana Vega Ángela Velasco Anne-Sophie Vesper Alessandra Viel Maaike P G Vreeswijk Sebastian A Wagner Anke Waha Logan C Walker Rhiannon J Walters Shan Wang-Gohrke Bernhard H F Weber Wilko Weichert Kerstin Wieland Lisa Wiesmüller Isabell Witzel Achim Wöckel Emma R Woodward Silke Zachariae Valentina Zampiga Christine Zeder-Göß Conxi Lázaro Arcangela De Nicolo Paolo Radice Christoph Engel Rita K Schmutzler David E Goldgar Amanda B Spurdle

Hum Mutat 2019 09;40(9):1557-1578

Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1002/humu.23818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772163PMC
September 2019

Morphomolecular analysis of the immune tumor microenvironment in human head and neck cancer.

Cancer Immunol Immunother 2019 Sep 23;68(9):1443-1454. Epub 2019 Aug 23.

Institute of Pathology, Charité Hospital, Berlin, Germany.

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http://dx.doi.org/10.1007/s00262-019-02378-wDOI Listing
September 2019

Classification and Prognostic Stratification of Bronchopulmonary Neuroendocrine Neoplasms.

Neuroendocrinology 2020 19;110(5):393-403. Epub 2019 Aug 19.

Department of Pathology, Technical University Munich, Munich, Germany.

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http://dx.doi.org/10.1159/000502776DOI Listing
August 2019

Large scale in vivo micro-RNA loss of function screen identified miR-29a, miR-100 and miR-155 as modulators of radioresistance and tumor-stroma communication.

Int J Cancer 2019 06 4;144(11):2774-2781. Epub 2019 Jan 4.

Division of Molecular & Translational Radiation Oncology, Heidelberg Institute of Radiation Oncology (HIRO), National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://doi.wiley.com/10.1002/ijc.32019
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http://dx.doi.org/10.1002/ijc.32019DOI Listing
June 2019

Several genotypes, one phenotype: PIK3CA/AKT1 mutation-negative hidradenoma papilliferum show genetic lesions in other components of the signalling network.

Pathology 2019 Jun 19;51(4):362-368. Epub 2019 Apr 19.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.pathol.2019.01.010DOI Listing
June 2019

HDAC inhibitors promote intestinal epithelial regeneration via autocrine TGFβ1 signalling in inflammation.

Mucosal Immunol 2019 05 23;12(3):656-667. Epub 2019 Jan 23.

Medical Department of Gastroenterology, Infectiology and Rheumatology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1038/s41385-019-0135-7DOI Listing
May 2019

Characterization of the tumor immune micromilieu and its interference with outcome after concurrent chemoradiation in patients with oropharyngeal carcinomas.

Oncoimmunology 2019 25;8(8):1614858. Epub 2019 May 25.

Department of Radiooncology and Radiotherapy, Berlin Institute of Health, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.

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http://dx.doi.org/10.1080/2162402X.2019.1614858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682352PMC
May 2019

Neoadjuvant versus definitive chemoradiation in patients with squamous cell carcinoma of the esophagus.

Radiat Oncol 2019 Apr 16;14(1):66. Epub 2019 Apr 16.

Department of Radiation Oncology, Klinikum rechts der Isar, Technical University Munich, Ismaninger Str. 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1186/s13014-019-1270-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469104PMC
April 2019

Early and late toxicity profiles of patients receiving immediate postoperative radiotherapy versus salvage radiotherapy for prostate cancer after prostatectomy.

Strahlenther Onkol 2019 Feb 4;195(2):131-144. Epub 2018 Sep 4.

Department of Radiation Oncology, Klinikum rechts der Isar, Technical University of Munich (TUM), Ismaninger Straße 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s00066-018-1359-2DOI Listing
February 2019

Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer.

Int J Cancer 2019 02 7;144(3):569-581. Epub 2018 Nov 7.

Charité Universitätsmedizin Berlin, Institute of Pathology, Laboratory of Molecular Tumor Pathology and Systems Biology, Berlin, Germany.

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http://dx.doi.org/10.1002/ijc.31892DOI Listing
February 2019

Discerning the Primary Carcinoma in Malignant Peritoneal and Pleural Effusions Using Imaging Mass Spectrometry-A Feasibility Study.

Proteomics Clin Appl 2019 01 29;13(1):e1800064. Epub 2018 Oct 29.

Mass Spectrometry Research Center and Departments of Biochemistry, Pharmacology, Medicine and Chemistry, Vanderbilt University, Nashville, TN, USA.

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http://doi.wiley.com/10.1002/prca.201800064
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http://dx.doi.org/10.1002/prca.201800064DOI Listing
January 2019

Composition and Clinical Impact of the Immunologic Tumor Microenvironment in Oral Squamous Cell Carcinoma.

J Immunol 2019 01 10;202(1):278-291. Epub 2018 Dec 10.

Department of Oral and Maxillofacial Surgery, Rechts der Isar Hospital, Technical University of Munich, 81675 Munich, Germany;

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http://dx.doi.org/10.4049/jimmunol.1800242DOI Listing
January 2019

Still a hopeless case for personalized oncology? Pancreatic cancer revisited.

Oncoscience 2019 Jan 22;6(1-2):285-286. Epub 2018 Aug 22.

Member of the German Cancer Consortium (DKTK), Institute of Pathology, Technical University Munich, 81675 Munich, Germany.

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http://dx.doi.org/10.18632/oncoscience.464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382256PMC
January 2019

Cortactin expression: Association with disease progression and survival in oral squamous cell carcinoma.

Head Neck 2018 12 20;40(12):2685-2694. Epub 2018 Nov 20.

Department of Oral and Cranio-Maxillofacial Surgery, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/hed.25515DOI Listing
December 2018

Tracer uptake in mediastinal and paraaortal thoracic lymph nodes as a potential pitfall in image interpretation of PSMA ligand PET/CT.

Eur J Nucl Med Mol Imaging 2018 07 1;45(7):1179-1187. Epub 2018 Mar 1.

Department of Nuclear Medicine, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00259-018-3965-8DOI Listing
July 2018

Advanced high-grade serous ovarian cancer: inverse association of KLK13 and KLK14 mRNA levels in tumor tissue and patients' prognosis.

J Cancer Res Clin Oncol 2018 Jun 15;144(6):1109-1118. Epub 2018 Mar 15.

Clinical Research Unit, Department of Obstetrics and Gynecology, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s00432-018-2623-7DOI Listing
June 2018

Regulation of Epithelial Plasticity Determines Metastatic Organotropism in Pancreatic Cancer.

Dev Cell 2018 06;45(6):696-711.e8

Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, 900 Biomedical Research Building II/III, 415 Curie Boulevard, Philadelphia, PA 19104, USA; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, 900 Biomedical Research Building II/III, 415 Curie Boulevard, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2018.05.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011231PMC
June 2018

Inflammation and PD-L1 expression in pulmonary neuroendocrine tumors.

Endocr Relat Cancer 2018 03 11;25(3):339-350. Epub 2018 Jan 11.

Department of PathologyTechnical University Munich, Munich, Germany.

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http://dx.doi.org/10.1530/ERC-17-0427DOI Listing
March 2018