Wenyu Lin

Wenyu Lin

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Wenyu Lin

Wenyu Lin

Publications by authors named "Wenyu Lin"

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Overexpression of c-Met in bone marrow mesenchymal stem cells improves their effectiveness in homing and repair of acute liver failure.

Stem Cell Res Ther 2017 07 5;8(1):162. Epub 2017 Jul 5.

Department of Infectious Disease, the First Affiliated Hospital with Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1186/s13287-017-0614-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499016PMC
July 2017

Apolipoprotein B100 is required for hepatitis C infectivity and Mipomersen inhibits hepatitis C.

World J Gastroenterol 2016 Dec;22(45):9954-9965

Esperance AK Schaefer, James Meixiong, Christina Mark, Daniel L Motola, Dahlene Fusco, Andrew Yang, Cynthia Brisac, Shadi Salloum, Wenyu Lin, Lee F Peng, Raymond T Chung, Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA 02114, United States.

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http://dx.doi.org/10.3748/wjg.v22.i45.9954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143762PMC
December 2016

IQGAP2 is a novel interferon-alpha antiviral effector gene acting non-conventionally through the NF-κB pathway.

J Hepatol 2016 11 9;65(5):972-979. Epub 2016 Jul 9.

Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.06.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656012PMC
November 2016

EFTUD2 on innate immunity.

Oncotarget 2015 Oct;6(32):32313-4

Department of Medicine, Liver Center and Gastrointestinal Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.18632/oncotarget.5863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741694PMC
October 2015

EFTUD2 Is a Novel Innate Immune Regulator Restricting Hepatitis C Virus Infection through the RIG-I/MDA5 Pathway.

J Virol 2015 Jul 15;89(13):6608-18. Epub 2015 Apr 15.

Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

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http://dx.doi.org/10.1128/JVI.00364-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468487PMC
July 2015

Mapping the Diversity of Follicular Helper T Cells in Human Blood and Tonsils Using High-Dimensional Mass Cytometry Analysis.

Cell Rep 2015 Jun 11;11(11):1822-33. Epub 2015 Jun 11.

Agency for Science, Technology and Research (A(∗)STAR), Singapore Immunology Network (SIgN), Singapore 138648, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.05.022DOI Listing
June 2015

The spliceosome factor SART1 exerts its anti-HCV action through mRNA splicing.

J Hepatol 2015 May 3;62(5):1024-32. Epub 2014 Dec 3.

Liver Center and Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2014.11.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404186PMC
May 2015

High-dimensional analysis of human CD8(+) T cell phenotype, function, and antigen specificity.

Curr Top Microbiol Immunol 2014 ;377:61-84

Singapore Immunology Network (SIgN), Agency for Science Technology and Research (A-STAR), Singapore, 138648, Republic of Singapore,

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http://link.springer.com/content/pdf/10.1007/82_2013_354.pdf
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http://link.springer.com/10.1007/82_2013_354
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http://dx.doi.org/10.1007/82_2013_354DOI Listing
September 2014

Human regulatory B cells combine phenotypic and genetic hallmarks with a distinct differentiation fate.

J Immunol 2014 Sep 30;193(5):2258-66. Epub 2014 Jul 30.

Biomedical Sciences Institutes, Singapore Immunology Network, Agency for Science, Technology and Research, Singapore 138648; INSERM U905, Normandie University, 76183 Rouen, France; and

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http://dx.doi.org/10.4049/jimmunol.1303214DOI Listing
September 2014

Expression of variant isoforms of the tyrosine kinase SYK determines the prognosis of hepatocellular carcinoma.

Cancer Res 2014 Mar 29;74(6):1845-56. Epub 2014 Jan 29.

Authors' Affiliations: State Key Laboratory of Oncology in South China; Department of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center; Department of Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; and Division of Pharmacy, The University of Texas M.D. Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959256PMC
March 2014

The AMPK-related kinase SNARK regulates hepatitis C virus replication and pathogenesis through enhancement of TGF-β signaling.

J Hepatol 2013 Nov 2;59(5):942-8. Epub 2013 Jul 2.

Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; The Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan; Japan Society for the Promotion of Science, Tokyo 102-8472, Japan.

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http://dx.doi.org/10.1016/j.jhep.2013.06.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866804PMC
November 2013

Pathogenesis of accelerated fibrosis in HIV/HCV co-infection.

J Infect Dis 2013 Mar;207 Suppl 1:S13-8

Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1093/infdis/jis926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611768PMC
March 2013

Development of an accurate index for predicting outcomes of patients with acute liver failure.

Gastroenterology 2012 Nov 8;143(5):1237-1243. Epub 2012 Aug 8.

Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2012.07.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480539PMC
November 2012

Inhibition of HCV by the serpin antithrombin III.

Virol J 2012 Oct 2;9:226. Epub 2012 Oct 2.

Division of Viral Pathogenesis, BIDMC, Boston, MA 02215, USA.

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http://dx.doi.org/10.1186/1743-422X-9-226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519617PMC
October 2012

ARF1 and GBF1 generate a PI4P-enriched environment supportive of hepatitis C virus replication.

PLoS One 2012 16;7(2):e32135. Epub 2012 Feb 16.

Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0032135PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281116PMC
August 2012

Activated T cells modulate immunosuppression by embryonic-and bone marrow-derived mesenchymal stromal cells through a feedback mechanism.

Cytotherapy 2012 Mar 5;14(3):274-84. Epub 2011 Dec 5.

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore.

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http://dx.doi.org/10.3109/14653249.2011.635853DOI Listing
March 2012

IL28B inhibits hepatitis C virus replication through the JAK-STAT pathway.

J Hepatol 2011 Aug 13;55(2):289-98. Epub 2010 Dec 13.

Gastrointestinal Unit, Department of Medicine, Warren 1007, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.jhep.2010.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068235PMC
August 2011

HIV infection increases HCV-induced hepatocyte apoptosis.

J Hepatol 2011 Apr 29;54(4):612-20. Epub 2010 Sep 29.

Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.jhep.2010.07.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060969PMC
April 2011

Hepatitis B screening, prophylaxis and re-activation in the era of rituximab-based chemotherapy.

Liver Int 2011 Mar 25;31(3):330-9. Epub 2010 Aug 25.

Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1111/j.1478-3231.2010.02332.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736143PMC
March 2011

Hepatitis C virus regulates transforming growth factor beta1 production through the generation of reactive oxygen species in a nuclear factor kappaB-dependent manner.

Gastroenterology 2010 Jun 12;138(7):2509-18, 2518.e1. Epub 2010 Mar 12.

Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1053/j.gastro.2010.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883661PMC
June 2010

Vector fragmentation: characterizing vector integrity in transfected clones by Southern blotting.

Biotechnol Prog 2010 Jan-Feb;26(1):11-20

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Centros, Singapore 138668.

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http://dx.doi.org/10.1002/btpr.281DOI Listing
May 2010

Reduction of insulin resistance with effective clearance of hepatitis C infection: results from the HALT-C trial.

Clin Gastroenterol Hepatol 2010 May 12;8(5):458-62. Epub 2010 Feb 12.

Department of Pediatrics, Batchelor Children's Research Institute, University of Miami, Miami, Florida, USA.

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http://dx.doi.org/10.1016/j.cgh.2010.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856733PMC
May 2010

Wide-ranging frequency preferences of auditory midbrain neurons: Roles of membrane time constant and synaptic properties.

Eur J Neurosci 2009 Jul 25;30(1):76-90. Epub 2009 Jun 25.

Department of Molecular and Integrative Physiology & Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL, USA.

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http://doi.wiley.com/10.1111/j.1460-9568.2009.06797.x
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http://dx.doi.org/10.1111/j.1460-9568.2009.06797.xDOI Listing
July 2009

Hepatic SOCS3 expression is strongly associated with non-response to therapy and race in HCV and HCV/HIV infection.

J Hepatol 2009 Apr 14;50(4):705-11. Epub 2009 Feb 14.

Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.jhep.2008.12.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146466PMC
April 2009

HIV increases HCV replication in a TGF-beta1-dependent manner.

Gastroenterology 2008 Mar 10;134(3):803-11. Epub 2008 Jan 10.

Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00165085080003
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http://dx.doi.org/10.1053/j.gastro.2008.01.005DOI Listing
March 2008

Serum apoptosis markers in acute liver failure: a pilot study.

Clin Gastroenterol Hepatol 2007 Dec 29;5(12):1477-83. Epub 2007 Oct 29.

Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S154235650700765
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http://dx.doi.org/10.1016/j.cgh.2007.08.007DOI Listing
December 2007

Generation of monoclonal antibodies to coelomocytes of the purple sea urchin Arbacia punctulata: characterization and phenotyping.

Dev Comp Immunol 2007 2;31(5):465-75. Epub 2006 Oct 2.

Department of Biology, University of Massachusetts--Boston, 100 Morrissey Blvd, Boston, MA 02125-3393, USA.

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http://dx.doi.org/10.1016/j.dci.2006.08.001DOI Listing
May 2007

Hepatitis C virus core protein blocks interferon signaling by interaction with the STAT1 SH2 domain.

J Virol 2006 Sep;80(18):9226-35

Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1128/JVI.00459-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563912PMC
September 2006

Cell-based models of sustained, interferon-sensitive hepatitis C virus genotype 1 replication.

J Virol Methods 2006 Mar 28;132(1-2):195-203. Epub 2005 Nov 28.

Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, GRJ 816, 55 Fruit Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.jviromet.2005.10.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865175PMC
March 2006

Leading inhibition to neural oscillation is important for time-domain processing in the auditory midbrain.

J Neurophysiol 2005 Jul 16;94(1):314-26. Epub 2005 Mar 16.

Department of Molecular and Integrative Physiology and Beckman Institute, University of Illinois, Urbana, USA.

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http://www.physiology.org/doi/10.1152/jn.00056.2005
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http://dx.doi.org/10.1152/jn.00056.2005DOI Listing
July 2005

Hepatitis C virus expression suppresses interferon signaling by degrading STAT1.

Gastroenterology 2005 Apr;128(4):1034-41

Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1053/j.gastro.2005.02.006DOI Listing
April 2005

Hepatitis C virus acts as a tumor accelerator by blocking apoptosis in a mouse model of hepatocarcinogenesis.

Hepatology 2005 Mar;41(3):660-7

Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1002/hep.20621DOI Listing
March 2005

Dual functional roles of Tie-2/angiopoietin in TNF-alpha-mediated angiogenesis.

Am J Physiol Heart Circ Physiol 2004 Jul;287(1):H187-95

Department of Radiation Oncology, Vanderbilt University Medical Center, 2220 Pierce Ave., Preston Research Bldg., Rm. 315, Nashville, TN 37232, USA.

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http://www.physiology.org/doi/10.1152/ajpheart.01058.2003
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http://dx.doi.org/10.1152/ajpheart.01058.2003DOI Listing
July 2004

Old world frog and bird vocalizations contain prominent ultrasonic harmonics.

J Acoust Soc Am 2004 Feb;115(2):910-3

Department of Physiological Science, University of California, 621 Charles E. Young Drive S., Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1121/1.1636851DOI Listing
February 2004

A humanized, nondepleting anti-CD4 antibody that blocks virus entry inhibits virus replication in rhesus monkeys chronically infected with simian immunodeficiency virus.

AIDS Res Hum Retroviruses 2002 Jul;18(11):747-55

Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Research East 113, 330 Brookline Avenue, Boston, MA 02215, USA.

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http://dx.doi.org/10.1089/08892220260139486DOI Listing
July 2002