Vera Gorbunova

Vera Gorbunova

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Vera Gorbunova

Publications by authors named "Vera Gorbunova"

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Mechanisms of cancer resistance in long-lived mammals.

Nat Rev Cancer 2018 07;18(7):433-441

University of Rochester, Department of Biology, Rochester, NY, USA.

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http://www.nature.com/articles/s41568-018-0004-9
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http://dx.doi.org/10.1038/s41568-018-0004-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015544PMC
July 2018

Cross-species Comparison of Proteome Turnover Kinetics.

Mol Cell Proteomics 2018 04 10;17(4):580-591. Epub 2018 Jan 10.

From the ‡Department of Biology, University of Rochester, NY;

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http://www.mcponline.org/lookup/doi/10.1074/mcp.RA117.000574
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http://dx.doi.org/10.1074/mcp.RA117.000574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880112PMC
April 2018

Accurate translation is important for longevity.

Aging (Albany NY) 2018 Mar;10(3):297-298

University of Rochester, Department of Biology, Rochester, NY 14627, USA.

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http://dx.doi.org/10.18632/aging.101398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892691PMC
March 2018

Haploinsufficiency of dramatically extends the lifespan of Sirt6-deficient mice.

Elife 2018 02 23;7. Epub 2018 Feb 23.

School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong.

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http://dx.doi.org/10.7554/eLife.32127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825207PMC
February 2018

Translation fidelity coevolves with longevity.

Aging Cell 2017 10 13;16(5):988-993. Epub 2017 Jul 13.

Department of Biology, University of Rochester, Rochester, NY, USA.

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http://dx.doi.org/10.1111/acel.12628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595694PMC
October 2017

Molecular Mechanisms Determining Lifespan in Short- and Long-Lived Species.

Trends Endocrinol Metab 2017 10 7;28(10):722-734. Epub 2017 Sep 7.

Department of Biology, University of Rochester, Rochester, NY 14627, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tem.2017.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679293PMC
October 2017

Beyond Making Ends Meet: DNA-PK, Metabolism, and Aging.

Cell Metab 2017 May;25(5):991-992

Department of Biology, University of Rochester, Rochester, NY 14627, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2017.04.022DOI Listing
May 2017

Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9.

Mol Cell 2017 May;66(4):503-516.e5

Center for Cell Signaling, University of Virginia, West Complex, 1335 Lee Street, Charlottesville, VA 22908, USA; Department of Biochemistry and Molecular Genetics, University of Virginia, PO Box 800733, Charlottesville, VA 22908, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.04.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556935PMC
May 2017

Non-canonical aging model systems and why we need them.

EMBO J 2017 04 20;36(8):959-963. Epub 2017 Mar 20.

Department of Biology, University of Rochester, Rochester, NY, USA.

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http://dx.doi.org/10.15252/embj.201796837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391153PMC
April 2017

A Randomized, Double-Blind, Placebo-Controlled, Phase III Study to Assess Efficacy and Safety of Weekly Farletuzumab in Combination With Carboplatin and Taxane in Patients With Ovarian Cancer in First Platinum-Sensitive Relapse.

J Clin Oncol 2016 07 21;34(19):2271-8. Epub 2016 Mar 21.

Ignace Vergote, University Hospitals Leuven, Leuven, Belgium; Deborah Armstrong, Johns Hopkins University, Baltimore, MD; Giovanni Scambia, Policlinico Universitario "A. Gemelli", Rome, Italy; Michael Teneriello, US Oncology, The Woodlands, TX; Jalid Sehouli, Charité - Universitätsmedizin Berlin, Berlin, Germany; Charles Schweizer, Susan C. Weil, Wenquan Wang, and Daniel O'Shannessy, Morphotek, Exton, PA; Aristotelis Bamias, Alexandra Hospital, Athens, Greece; Keiichi Fujiwara, Saitama Medical University International Medical Center, Hidaka-City, Saitama; and Kazunori Ochiai, Jikei University School of Medicine, Minato-Ku, Tokyo, Japan; Christopher Poole, University Hospital Coventry, Coventry, United Kingdom; Vera Gorbunova, Russian Oncology Research Center, Moscow, Russia; and Thomas J. Herzog, University of Cincinnati, Cincinnati, OH.

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http://dx.doi.org/10.1200/JCO.2015.63.2596DOI Listing
July 2016

Pericellular Brush and Mechanics of Guinea Pig Fibroblast Cells Studied with AFM.

Biophys J 2016 Jul;111(1):236-46

Department of Mechanical Engineering, Tufts University, Medford, Massachusetts; Department of Physics, Tufts University, Medford, Massachusetts; Department of Biomedical Engineering, Tufts University, Medford, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2016.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944720PMC
July 2016

The Insulin-Like Growth Factor System in the Long-Lived Naked Mole-Rat.

PLoS One 2015 22;10(12):e0145587. Epub 2015 Dec 22.

The Division of Endocrinology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0145587PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694111PMC
June 2016

DNA double strand break repair, aging and the chromatin connection.

Mutat Res 2016 06 15;788:2-6. Epub 2016 Feb 15.

University of Rochester, Department of Biology, Hutchison Hall, RC, Rochester, NY 14627, USA.

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http://dx.doi.org/10.1016/j.mrfmmm.2016.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887314PMC
June 2016

Dangerous Entrapment for NRF2.

Cell 2016 Jun;165(6):1312-1313

Department of Biology, 434 Hutchison Hall, River Campus, University of Rochester, Rochester, NY 14627, USA.

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http://dx.doi.org/10.1016/j.cell.2016.05.061DOI Listing
June 2016

Organization of the Mammalian Ionome According to Organ Origin, Lineage Specialization, and Longevity.

Cell Rep 2015 Nov 5;13(7):1319-1326. Epub 2015 Nov 5.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.10.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771060PMC
November 2015

SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner.

Cell Cycle 2015 ;14(2):269-76

a Department of Clinical Laboratory Medicine; Shanghai Tenth People's Hospital; School of Life Sciences and Technology; Tongji University ; Shanghai , China.

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http://dx.doi.org/10.4161/15384101.2014.980641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614943PMC
September 2015

Randomized phase II study of carboplatin and paclitaxel with either linifanib or placebo for advanced nonsquamous non-small-cell lung cancer.

J Clin Oncol 2015 Feb 5;33(5):433-41. Epub 2015 Jan 5.

Suresh S. Ramalingam and Taofeek K. Owonikoko, Winship Cancer Institute of Emory University, Atlanta, GA; Mikhail Shtivelband, Ironwood Cancer and Research Centers, Chandler, AZ; Ross A. Soo, National University Cancer Institute, National University Health System, Singapore, Singapore; Carlos H. Barrios, Pontifícia Universidade Católica do Rio Grande do Sul School of Medicine, Porto Alegre; José G.M. Segalla, Hospital Amaral Carvalho, Jau; Jose R. Pereira, Instituto Brasileiro de Cancerologia Toracica, Sao Paulo, Brazil; Anatoly Makhson, Moscow City Oncology Hospital No. 62; Vera A. Gorbunova, N.N. Blokhin Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia; Kenneth B. Pittman, The Queen Elizabeth Hospital, Woodville, South Australia, Australia; Petr Kolman, Hospital Kyjov, Kyjov, Czech Republic; Gordan Srkalovic, Sparrow Regional Cancer Center, Lansing, MI; Chandra P. Belani, Penn State Hershey Cancer Institute, Hershey; Rita Axelrod, Thomas Jefferson University Hospital, Philadelphia, PA; Qin Qin, Jiang Qian, Evelyn M. McKeegan, Viswanath Devanarayan, Mark D. McKee, Justin L. Ricker, and Dawn M. Carlson, AbbVie, North Chicago, IL.

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http://dx.doi.org/10.1200/JCO.2014.55.7173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478045PMC
February 2015

Regulation of Rad51 promoter.

Cell Cycle 2014 29;13(13):2038-45. Epub 2014 Apr 29.

Department of Biology; University of Rochester; Rochester, NY USA.

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http://dx.doi.org/10.4161/cc.29016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111695PMC
January 2015

Primary results of ROSE/TRIO-12, a randomized placebo-controlled phase III trial evaluating the addition of ramucirumab to first-line docetaxel chemotherapy in metastatic breast cancer.

J Clin Oncol 2015 Jan 2;33(2):141-8. Epub 2014 Sep 2.

John R. Mackey, Cross Cancer Institute; Francois Thireau and Helena Fung, Translational Research in Oncology, Edmonton; Marc Webster, Tom Baker Cancer Centre, Calgary, Alberta; Karen A. Gelmon, British Columbia Cancer Agency, Vancouver, British Columbia; Sunil Verma, Sunnybrook Health Sciences Center; Lorinda Simms, Eli Lilly, Toronto, Ontario, Canada; Manuel Ramos-Vazquez, Centro Oncológico de Galicia "José Antonio Quiroga y Piñeiro," A Coruña; Miguel Martin, Instituto de Investigación Sanitaria Gregorio Marañon, Universidad Complutense, Madrid, Spain; Oleg Lipatov, Republican Clinical Oncology Dispensary, Bashkortostan Republic Ministry of Health, Ufa; Dmitriy Krasnozhon, Leningrad Regional Oncology Dispensary, Leningrad; Vladimir Semiglazov, Institute of Oncology N.N. Petrov; Alexey Manikhas, City Clinical Oncology Dispensary, St Petersburg; Vera Gorbunova, N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia; Nicole McCarthy, ICON Cancer Care Wesley, Brisbane, Queensland, Australia; Gottfried E. Konecny, University of California Los Angeles, Los Angeles, CA; Roberto Hegg, Hospital Pérola Byigton Centro de Referência da Saúde da Mulher, Sao Paulo, Brazil; Dany Abi Gerges, Middle East Institute of Health, Bsalim, Lebanon; Marc Buyse, International Drug Development Institute, Louvain-la-Neuve, Belgium; and Ayman Ibrahim, ImClone Systems, Bridgewater, NJ.

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http://dx.doi.org/10.1200/JCO.2014.57.1513DOI Listing
January 2015

Linifanib versus Sorafenib in patients with advanced hepatocellular carcinoma: results of a randomized phase III trial.

J Clin Oncol 2015 Jan 8;33(2):172-9. Epub 2014 Dec 8.

Calin Cainap, Institute of Oncology, Cluj-Napoca, Romania; Shukui Qin, Chinese People's Liberation Army Cancer Center, Bayi Hospital, Beijing; Hongming Pan, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou; Ying Cheng, Tumor Hospital of Jilin Province, Changchun, People's Republic of China; Wen-Tsung Huang, Chi Mei Medical Center, Liouying; Pei-Jer Chen, National Taiwan University Hospital, Taipei, Taiwan, Republic of China; Ik Joo Chung, Chonnam National University, Hwasun Hospital, Hwasun, Jeollonam-do; Yoon-Koo Kang, Asan Medical Center, University of Ulsan, Seoul, Republic of Korea; Masatoshi Kudo, Kinki University, Osaka, Japan; Han-Chong Toh, National Cancer Centre, Singapore, Singapore; Vera Gorbunova, Russian Academy of Medical Sciences, Moscow, Russia; Ferry A.L.M. Eskens, Cancer Institute, Erasmus University Medical Center, Rotterdam, the Netherlands; Jiang Qian, Mark D. McKee, Justin L. Ricker, Dawn M. Carlson, AbbVie, North Chicago, IL; Saied El-Nowiem, Alexandria University, Alexandria, Egypt.

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http://dx.doi.org/10.1200/JCO.2013.54.3298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279237PMC
January 2015

The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations.

Bioinformatics 2014 Dec 28;30(24):3558-60. Epub 2014 Aug 28.

Integrative Genomics of Ageing Group, Institute of Integrative Biology, University of Liverpool, Liverpool, UK, Broad Institute of MIT and Harvard, Cambridge, MA, USA, Department of Biology, University of Rochester, NY, USA, Vertebrate and Health Genomics, The Genome Analysis Center, Norwich, UK, Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden and Department of Genetics, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253829PMC
December 2014

Human Genomics. Sleeping dogs of the genome.

Science 2014 Dec;346(6214):1187-8

Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI 02912, USA.

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http://www.sciencemag.org/lookup/doi/10.1126/science.aaa3177
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http://dx.doi.org/10.1126/science.aaa3177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312280PMC
December 2014

SIRT6: a promising target for cancer prevention and therapy.

Adv Exp Med Biol 2014 ;818:181-96

Department of Biology, University of Rochester, 432 Hutchison Hall, River Campus, Rochester, NY, 14627-0211, USA.

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http://dx.doi.org/10.1007/978-1-4471-6458-6_9DOI Listing
November 2014

Randomized phase II open-label study of mFOLFOX6 in combination with linifanib or bevacizumab for metastatic colorectal cancer.

Clin Colorectal Cancer 2014 Sep 23;13(3):156-163.e2. Epub 2014 Jun 23.

Department of Oncology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

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http://dx.doi.org/10.1016/j.clcc.2014.04.001DOI Listing
September 2014

Axitinib for the treatment of metastatic renal cell carcinoma: recommendations for therapy management to optimize outcomes.

Am J Clin Oncol 2014 Aug;37(4):397-403

*Renal Cancer Unit, Department of Medicine, Royal Marsden, London, UK †H. Lee Moffitt Cancer Center, Tampa, FL ‡Cleveland Clinic Cancer Institute, Cleveland, OH §Massachusetts General Hospital, Boston, MA ∥N.N. Blokhin Russian Cancer Research Center, Moscow, Russia ¶M.D. Anderson Cancer Center, Houston #Texas Oncology PA Sammons Cancer Center/Baylor, Dallas, TX **Department of Urology, University of Munich, Munich, Germany.

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http://pdfs.journals.lww.com/amjclinicaloncology/2014/08000/
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/COC.0b013e31827b45f9DOI Listing
August 2014

P21-PARP-1 pathway is involved in cigarette smoke-induced lung DNA damage and cellular senescence.

PLoS One 2013 11;8(11):e80007. Epub 2013 Nov 11.

Department of Environmental Medicine, Lung Biology and Disease Program, Rochester, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080007PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823706PMC
August 2014

Comparative genetics of longevity and cancer: insights from long-lived rodents.

Nat Rev Genet 2014 Aug 1;15(8):531-40. Epub 2014 Jul 1.

Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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http://dx.doi.org/10.1038/nrg3728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353926PMC
August 2014

Knock-in reporter mice demonstrate that DNA repair by non-homologous end joining declines with age.

PLoS Genet 2014 Jul 17;10(7):e1004511. Epub 2014 Jul 17.

Department of Biology, University of Rochester, Rochester, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102425PMC
July 2014

A correlative biomarker analysis of the combination of bevacizumab and carboplatin-based chemotherapy for advanced nonsquamous non-small-cell lung cancer: results of the phase II randomized ABIGAIL study (BO21015).

J Thorac Oncol 2014 Jun;9(6):848-55

*State Key Laboratory of Southern China, Hong Kong Cancer Institute, Department of Clinical Oncology, Prince of Wales Hospital, Hong Kong, China; †Russian Research Oncology Center n.a. N.N. Blokhin of the Russian Academy of Medical Sciences, Moscow, Russia; ‡Országos Korányi TBC és Pulmonológiai Intézet, Budapest, Hungary; §Department of Pulmonology, Markusovszky University Hospital, Budapest, Hungary; ‖Arkhangelsk Regional Clinical Oncology Dispensary, Perm, Russia; ¶Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan; #Roche Products Limited, Welwyn Garden City, Hertfordshire, United Kingdom; **F. Hoffmann-La Roche Ltd., Basel, Switzerland; and ††Department of Thoracic Oncology, Lung Clinic Grosshansdorf, Member of the German Center for Lung Research (DZL), Grosshansdorf, Germany.

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http://dx.doi.org/10.1097/JTO.0000000000000160DOI Listing
June 2014

Mitochondrial inverted repeats strongly correlate with lifespan: mtDNA inversions and aging.

PLoS One 2013 17;8(9):e73318. Epub 2013 Sep 17.

Department of Biology, University of Rochester, Rochester, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0073318PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775743PMC
April 2014

Utilization of Rad51C promoter for transcriptional targeting of cancer cells.

Oncotarget 2014 Apr;5(7):1805-11

School of Life Sciences and Technology, Tongji University, Shanghai, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039114PMC
http://dx.doi.org/10.18632/oncotarget.1792DOI Listing
April 2014

Pharmacogenomic assessment of cisplatin-based chemotherapy outcomes in ovarian cancer.

Pharmacogenomics 2014 Feb;15(3):329-37

Department of Molecular Bases of Human Genetics, Institute of Molecular Genetics, Russian Academy of Sciences, Kurchatov sq., 2, Moscow, Russia.

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http://dx.doi.org/10.2217/pgs.13.237DOI Listing
February 2014

Novel husbandry techniques support survival of naked mole rat (Heterocephalus glaber) pups.

J Am Assoc Lab Anim Sci 2014 Jan;53(1):89-91

Department of Biology, University of Rochester, University of Rochester Medical Center, Rochester, New York, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894653PMC
January 2014

Health-related quality of life in patients with advanced nonsquamous non-small-cell lung cancer receiving bevacizumab or bevacizumab-plus-pemetrexed maintenance therapy in AVAPERL (MO22089).

J Thorac Oncol 2013 Nov;8(11):1409-16

*Department of Thoracic Oncology, Lungenfachklinik Immenhausen, Immenhausen, Germany; †N.N. Blokhin Cancer Research Center of Russia, Moscow, Russia; ‡Department of Pulmonary Medicine, Lungkliniken, Linköping, Sweden; §Pulmonary and Thoracic Oncology Department, Hôpital Albert Calmette, CHRU de Lille, Lille, France; ‖Department of Medical Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea; ¶Department of Hematology and Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; #Department of Cardio-Thoracic Medicine, University of Pisa, Pisa, Italy; **Service de Pneumologie, Assistance Publique - Hopitaux de Paris, Hôpital Saint-Antoine, Paris, France; ††Global Medical Affairs, Genentech, Inc., South San Francisco, California; and ‡‡Service d' Oncologie Multidisciplinaire & Innovations Thérapeutiques, Aix Marseille University, Assistance Publique Hopitaux de Marseille, INSERM CIC, Multidisciplinary Oncology and Therapeutic Innovations, Marseille, France.

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http://dx.doi.org/10.1097/JTO.0b013e3182a46bcfDOI Listing
November 2013

Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations.

J Clin Oncol 2013 Sep 1;31(27):3327-34. Epub 2013 Jul 1.

Lecia V. Sequist, Massachusetts General Hospital and Harvard Medical School, Boston, MA; James Chih-Hsin Yang, National Taiwan University Hospital; Chun-Ming Tsai, Taipei Veterans General Hospital, Taipei; Wu-Chou Su, National Cheng Kung University Hospital, Tainan, Taiwan; Nobuyuki Yamamoto, Shizuoka Cancer Center, Shizuoka; Terufumi Kato, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan; Kenneth O'Byrne, St James' Hospital, Dublin, Ireland; Vera Hirsh, McGill University, Montreal, Quebec, Canada; Tony Mok, Prince of Wales Hospital, Hong Kong, China; Sarayut Lucien Geater, Songklanagarind Hospital, Songkla, Thailand; Sergey Orlov, Pavlov State Medical University, St Petersburg; Vera Gorbunova, GU Russian Oncological Research Centre, Moscow, Russia; Michael Boyer, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia; Jaafar Bennouna, Institut de Cancérologie de l'Ouest-site René Gauducheau, Nantes, France; Ki Hyeong Lee, Chungbuk National University Hospital, Cheongju, South Korea; Riyaz Shah, Maidstone and Tunbridge Wells National Health Service Trust, Maidstone Hospital, Maidstone; Dan Massey, Victoria Zazulina, and Mehdi Shahidi, Boehringer Ingelheim, Bracknell, United Kingdom; and Martin Schuler, West German Cancer Center, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1200/JCO.2012.44.2806DOI Listing
September 2013

Cancer resistance in the blind mole rat is mediated by concerted necrotic cell death mechanism.

Proc Natl Acad Sci U S A 2012 Nov 5;109(47):19392-6. Epub 2012 Nov 5.

Department of Biology, University of Rochester, Rochester, NY 14627, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1217211109
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http://dx.doi.org/10.1073/pnas.1217211109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511137PMC
November 2012

Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence.

Proc Natl Acad Sci U S A 2012 Jul 2;109(29):11800-5. Epub 2012 Jul 2.

Department of Biology, University of Rochester, Rochester, NY 14627, USA.

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http://dx.doi.org/10.1073/pnas.1200583109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406824PMC
July 2012

Replicatively senescent cells are arrested in G1 and G2 phases.

Aging (Albany NY) 2012 Jun;4(6):431-5

Department of Biology, University of Rochester, Rochester, NY 14627, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409679PMC
http://dx.doi.org/10.18632/aging.100467DOI Listing
June 2012

SIRT1 as a therapeutic target in inflammaging of the pulmonary disease.

Prev Med 2012 May 8;54 Suppl:S20-8. Epub 2011 Dec 8.

Department of Environmental Medicine, Lung Biology and Disease Program, University of Rochester Medical Center, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1016/j.ypmed.2011.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311735PMC
May 2012

Rad51 promoter-targeted gene therapy is effective for in vivo visualization and treatment of cancer.

Mol Ther 2012 Feb 18;20(2):347-55. Epub 2011 Oct 18.

Department of Biology, University of Rochester, Rochester, New York 14627, USA.

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http://dx.doi.org/10.1038/mt.2011.215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277325PMC
February 2012

Pharmacogenomics of cisplatin-based chemotherapy in ovarian cancer patients of different ethnic origins.

Pharmacogenomics 2012 Jan 21;13(2):171-8. Epub 2011 Dec 21.

Department of Molecular Bases of Human Genetics, Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia.

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http://dx.doi.org/10.2217/pgs.11.140DOI Listing
January 2012

SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cells.

Cell Cycle 2011 Sep 15;10(18):3153-8. Epub 2011 Sep 15.

University of Rochester, Rochester, NY, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218623PMC
http://dx.doi.org/10.4161/cc.10.18.17435DOI Listing
September 2011

Repairing split ends: SIRT6, mono-ADP ribosylation and DNA repair.

Aging (Albany NY) 2011 Sep;3(9):829-35

Department of Biology, University of Rochester, Rochester, NY 14627, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227448PMC
http://dx.doi.org/10.18632/aging.100389DOI Listing
September 2011

Establishing primary adult fibroblast cultures from rodents.

J Vis Exp 2010 Oct 5(44). Epub 2010 Oct 5.

Department of Biology, University of Rochester, USA.

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http://www.jove.com/index/Details.stp?ID=2033
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http://dx.doi.org/10.3791/2033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185624PMC
October 2010

Analysis of DNA double-strand break (DSB) repair in mammalian cells.

J Vis Exp 2010 Sep 8(43). Epub 2010 Sep 8.

Department of Biology, University of Rochester.

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http://dx.doi.org/10.3791/2002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157866PMC
September 2010

Multicenter phase III comparison of cisplatin/S-1 with cisplatin/infusional fluorouracil in advanced gastric or gastroesophageal adenocarcinoma study: the FLAGS trial.

J Clin Oncol 2010 Mar 16;28(9):1547-53. Epub 2010 Feb 16.

Department of Gastrointestinal Medical Oncology, The University of Texas M. D. Anderson Cancer Center, TX 77030, USA.

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March 2010

Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat.

Proc Natl Acad Sci U S A 2009 Nov 26;106(46):19352-7. Epub 2009 Oct 26.

Department of Biology, University of Rochester, Rochester, NY 14627, USA.

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http://dx.doi.org/10.1073/pnas.0905252106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780760PMC
November 2009

Rodents for comparative aging studies: from mice to beavers.

Age (Dordr) 2008 Sep 25;30(2-3):111-9. Epub 2008 Jun 25.

Department of Biology, University of Rochester, 213 Hutchison Hall, Rochester, NY 14627, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527635PMC
September 2008