Torsten Christ

Torsten Christ

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Torsten Christ

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Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes.

Cell Signal 2019 Nov 22;63:109362. Epub 2019 Jul 22.

Institute of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany; DZHK (German Center for Cardiovascular Research), Partner site Hamburg/Kiel/Lübeck, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2019.109362DOI Listing
November 2019

Chronic intermittent tachypacing by an optogenetic approach induces arrhythmia vulnerability in human engineered heart tissue.

Cardiovasc Res 2019 Oct 9. Epub 2019 Oct 9.

Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1093/cvr/cvz245DOI Listing
October 2019

German Cardiac Society Working Group on Cellular Electrophysiology state-of-the-art paper: impact of molecular mechanisms on clinical arrhythmia management.

Clin Res Cardiol 2019 Jun 10;108(6):577-599. Epub 2018 Oct 10.

Institute of Pharmacology and Toxicology, University Medical Center Göttingen, Georg-August University Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany.

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http://dx.doi.org/10.1007/s00392-018-1377-1DOI Listing
June 2019

DPP10 is a new regulator of Nav1.5 channels in human heart.

Int J Cardiol 2019 06 3;284:68-73. Epub 2019 Jan 3.

Rudolf-Boehm-Institute of Pharmacology and Toxicology, Leipzig University, Leipzig, Germany; Department of Pharmacology and Toxicology, TU Dresden, Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2018.12.072DOI Listing
June 2019

Long-term results after the Ross procedure with the decellularized AutoTissue Matrix P® bioprosthesis used for pulmonary valve replacement.

Eur J Cardiothorac Surg 2019 May;55(5):885-892

Department of Cardiovascular Surgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1093/ejcts/ezy377DOI Listing
May 2019

Cardiac glial cells release neurotrophic S100B upon catheter-based treatment of atrial fibrillation.

Sci Transl Med 2019 05;11(493)

Department of Cardiology-Electrophysiology, cNEP (cardiac Neuro- and Electrophysiology research group), University Heart Centre, University Hospital Hamburg-Eppendorf, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1126/scitranslmed.aav7770DOI Listing
May 2019

Mechanistic role of the CREB-regulated transcription coactivator 1 in cardiac hypertrophy.

J Mol Cell Cardiol 2019 02 4;127:31-43. Epub 2018 Dec 4.

Department of Clinical Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg, Kiel, Lübeck, Germany; Institute of Pharmacy, University of Hamburg, Bundesstr. 45, 20146 Hamburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00222828183072
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http://dx.doi.org/10.1016/j.yjmcc.2018.12.001DOI Listing
February 2019

Normalization of force to muscle cross-sectional area: A helpful attempt to reduce data scattering in contractility studies?

Acta Physiol (Oxf) 2018 12;224(4):e13202

Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://doi.wiley.com/10.1111/apha.13202
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http://dx.doi.org/10.1111/apha.13202DOI Listing
December 2018

Atrial-like Engineered Heart Tissue: An In Vitro Model of the Human Atrium.

Stem Cell Reports 2018 12 8;11(6):1378-1390. Epub 2018 Nov 8.

Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294072PMC
December 2018

Rat atrial engineered heart tissue: a new in vitro model to study atrial biology.

Basic Res Cardiol 2018 09 3;113(5):41. Epub 2018 Sep 3.

DZHK (German Centre for Cardiovascular Research), Partner site Hamburg/Kiel/Lübeck, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00395-018-0701-2DOI Listing
September 2018

Human Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue as a Sensitive Test System for QT Prolongation and Arrhythmic Triggers.

Circ Arrhythm Electrophysiol 2018 07;11(7):e006035

Department of Experimental Pharmacology and Toxicology, University Medical Center, Hamburg-Eppendorf, Germany (M.D.L., T.K., M.P., M.L.S., A.H., T.E., T.C.)

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http://dx.doi.org/10.1161/CIRCEP.117.006035DOI Listing
July 2018

In Vitro Negative Inotropic Effect of Low Concentrations of Bupivacaine Relates to Diminished Ca2+ Sensitivity but Not to Ca2+ Handling or β-Adrenoceptor Signaling.

Anesthesiology 2018 06;128(6):1175-1186

From the Department of Experimental Pharmacology and Toxicology (F. Flenner, M.N., F. Friedrich, T.C.) Institute of Experimental Cardiovascular Research, Cardiovascular Research Center (S.S., V.N.), University Hospital Hamburg-Eppendorf, Hamburg, Germany Department of Pharmacology and Toxicology (N.A., U.R., T.C.) Department of Anesthesiology and Intensive Care Medicine (N.A., T.K., S.N.S.), Medical Faculty Carl Gustav Carus, Dresden, Germany Department of Anesthesiology and Intensive Care Medicine, University of Leipzig, Germany (S.N.S.) the German Center for Cardiovascular Research, partner site Hamburg/Kiel/Lübeck, Germany (F. Flenner, S.S., F. Friedrich, V.N., T.C.) Current position: Institute for Experimental Cardiovascular Medicine, University Heart Center, Medical Center, and Faculty of Medicine, University of Freiburg, Freiburg, Germany (U.R.).

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http://dx.doi.org/10.1097/ALN.0000000000002180DOI Listing
June 2018

Inhibition of Small Conductance Calcium-Activated Potassium (SK) Channels Prevents Arrhythmias in Rat Atria During β-Adrenergic and Muscarinic Receptor Activation.

Front Physiol 2018 5;9:510. Epub 2018 Jun 5.

Cardiac Physiology Laboratory, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.3389/fphys.2018.00510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996028PMC
June 2018

Risks and Challenges of Surgery for Aortic Prosthetic Valve Endocarditis.

Heart Lung Circ 2018 Mar 21;27(3):333-343. Epub 2017 Jun 21.

Klinik für Kardiovaskuläre Chirurgie, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1016/j.hlc.2017.05.143DOI Listing
March 2018

Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived Cardiomyocytes.

Stem Cell Reports 2018 03 8;10(3):822-833. Epub 2018 Feb 8.

Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Institut für Experimentelle Pharmakologie und Toxikologie, Universitätsklinikum Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918194PMC
March 2018

The Ross Procedure in Adults: Long-Term Results of Homografts and Stentless Xenografts for Pulmonary Valve Replacement.

Thorac Cardiovasc Surg 2017 Dec 10;65(8):656-661. Epub 2016 Aug 10.

Department of Cardiovascular Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1055/s-0036-1586157DOI Listing
December 2017

Hemodynamics of Pericardial Aortic Valves: Contemporary Stented versus Stentless Valves in a Matched Comparison.

Ann Thorac Cardiovasc Surg 2017 Dec 8;23(6):298-303. Epub 2017 Sep 8.

Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Cardiovascular Surgery, Berlin, Germany.

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http://dx.doi.org/10.5761/atcs.oa.17-00061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738451PMC
December 2017

EDC Cross-linking of Decellularized Tissue: A Promising Approach?

Tissue Eng Part A 2017 07 15;23(13-14):675-682. Epub 2017 May 15.

2 Department of Cardiovascular Surgery, Charité-Universitätsmedizin Berlin , Berlin, Germany .

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http://dx.doi.org/10.1089/ten.TEA.2016.0416DOI Listing
July 2017

Redo procedures for degenerated stentless aortic xenografts and the role of valve-in-valve transcatheter techniques.

Eur J Cardiothorac Surg 2017 04;51(4):653-659

Department of Cardiology, Campus Charité Mitte, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1093/ejcts/ezw397DOI Listing
April 2017

Cafedrine/Theodrenaline (20:1) Is an Established Alternative for the Management of Arterial Hypotension in Germany-a Review Based on a Systematic Literature Search.

Front Pharmacol 2017 21;8:68. Epub 2017 Feb 21.

Department of Anesthesiology and Intensive Care Medicine, Philipps-University Marburg Marburg, Germany.

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http://dx.doi.org/10.3389/fphar.2017.00068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318387PMC
February 2017

Refractoriness in human atria: Time and voltage dependence of sodium channel availability.

J Mol Cell Cardiol 2016 Dec 20;101:26-34. Epub 2016 Oct 20.

Center for Cardiological Innovation and Center for Biomedical Computing, Simula Research Laboratory, Oslo, Norway; Department of Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2016.10.009DOI Listing
December 2016

Sutureless Aortic Valve Replacement in a Patient with Transfemoral Aortic Valve Replacement and Left Ventricular Hypertrophy.

Thorac Cardiovasc Surg Rep 2016 Dec 10;5(1):21-23. Epub 2015 Jul 10.

Department of Cardiovascular Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1055/s-0035-1554991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177443PMC
December 2016

Clinical outcome and hemodynamic behavior of the Labcor Dokimos Plus aortic valve.

J Cardiothorac Surg 2016 Nov 29;11(1):160. Epub 2016 Nov 29.

Department of Cardiovascular Surgery, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.

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http://dx.doi.org/10.1186/s13019-016-0561-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129248PMC
November 2016

Long-Term Outcome of the Sorin Freedom SOLO Stentless Aortic Valve.

J Heart Valve Dis 2016 11;25(6):679-684

Department of Cardiovascular Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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November 2016

Block of Na(+)/Ca(2+) exchanger by SEA0400 in human right atrial preparations from patients in sinus rhythm and in atrial fibrillation.

Eur J Pharmacol 2016 Oct 29;788:286-293. Epub 2016 Jun 29.

Department of Pharmacology and Toxicology, Medical Faculty, TU Dresden, Fetscherstr. 74, d-01307 Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2016.06.050DOI Listing
October 2016

Ca(2+)-Currents in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Effects of Two Different Culture Conditions.

Front Pharmacol 2016 12;7:300. Epub 2016 Sep 12.

Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-EppendorfHamburg, Germany; Partner Site Hamburg/Kiel/Lübeck, German Centre for Cardiovascular Research (DZHK)Hamburg, Germany.

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http://dx.doi.org/10.3389/fphar.2016.00300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018497PMC
September 2016

In permanent atrial fibrillation, PDE3 reduces force responses to 5-HT, but PDE3 and PDE4 do not cause the blunting of atrial arrhythmias.

Br J Pharmacol 2016 08 18;173(16):2478-89. Epub 2016 Jul 18.

Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1111/bph.13525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959958PMC
August 2016

Risk and Outcome of Aortic Valve Surgery in the Transcatheter Valve Era: The Gender Aspect.

Ann Thorac Cardiovasc Surg 2015 25;21(5):446-51. Epub 2015 May 25.

Department of Cardiovascular Surgery, Charité Hospital, Medical University, Berlin, Germany.

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http://dx.doi.org/10.5761/atcs.oa.14-00291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904853PMC
July 2016

Human Engineered Heart Tissue: Analysis of Contractile Force.

Stem Cell Reports 2016 07 19;7(1):29-42. Epub 2016 May 19.

Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2016.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944531PMC
July 2016

Surgery for prosthetic valve endocarditis: associations between morbidity, mortality and costs.

Interact Cardiovasc Thorac Surg 2016 06 9;22(6):784-91. Epub 2016 Mar 9.

Klinik für Kardiovaskuläre Chirurgie, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1093/icvts/ivw035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986780PMC
June 2016

Frozen Elephant Trunk Technique in a Patient with Multiple Previous Cardiac Procedures: A Case Report.

Med Sci Monit Basic Res 2016 Jun 30;22:67-9. Epub 2016 Jun 30.

Department of Cardiovascular Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938122PMC
http://dx.doi.org/10.12659/msmbr.900105DOI Listing
June 2016

Ranolazine antagonizes catecholamine-induced dysfunction in isolated cardiomyocytes, but lacks long-term therapeutic effects in vivo in a mouse model of hypertrophic cardiomyopathy.

Cardiovasc Res 2016 Jan 3;109(1):90-102. Epub 2015 Nov 3.

Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, Martinistraße 52, D-20246 Hamburg, Germany DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany

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http://cardiovascres.oxfordjournals.org/content/cardiovascre
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http://dx.doi.org/10.1093/cvr/cvv247DOI Listing
January 2016

β 1 Adrenoceptor antagonistic effects of the supposedly selective β 2 adrenoceptor antagonist ICI 118,551 on the positive inotropic effect of adrenaline in murine hearts.

Pharmacol Res Perspect 2015 Oct 31;3(5):e00168. Epub 2015 Jul 31.

Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf Hamburg, Germany ; DZHK (German Centre for Cardiovascular Research) Hamburg/Kiel/Lübeck, Germany.

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http://doi.wiley.com/10.1002/prp2.168
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http://dx.doi.org/10.1002/prp2.168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618639PMC
October 2015

The St. Jude Toronto stentless bioprosthesis: up to 20 years follow-up in younger patients.

Heart Surg Forum 2015 Aug 30;18(4):E129-33. Epub 2015 Aug 30.

Charité-Universitätsmedizin Berlin, Department of Cardiovascular Surgery, Berlin, Germany.

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http://dx.doi.org/10.1532/hsf.1252DOI Listing
August 2015

Effects of proarrhythmic drugs on relaxation time and beating pattern in rat engineered heart tissue.

Basic Res Cardiol 2014 11;109(6):436. Epub 2014 Sep 11.

Department of Experimental Pharmacology and Toxicology, University Medical Centre Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00395-014-0436-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160570PMC
May 2015

Prolonged action potentials in HCM-derived iPSC--biology or artefact?

Cardiovasc Res 2015 Apr 17;106(1). Epub 2015 Feb 17.

Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Center for Biomedical Computing and Center for Cardiological Innovation, Oslo, Norway.

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http://dx.doi.org/10.1093/cvr/cvv038DOI Listing
April 2015

LQT1-phenotypes in hiPSC: Are we measuring the right thing?

Proc Natl Acad Sci U S A 2015 Apr 20;112(16):E1968. Epub 2015 Mar 20.

Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany; and DZHK (German Centre for Cardiovascular Research), German Centre for Cardiovascular Research, partner site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1073/pnas.1503347112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413273PMC
April 2015

Suitability of the rat subdermal model for tissue engineering of heart valves.

Med Sci Monit Basic Res 2014 Dec 10;20:194-9. Epub 2014 Dec 10.

Department of Cardiovascular Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.12659/MSMBR.893088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270313PMC
December 2014

Hemodynamic behavior of stentless aortic valves in long term follow-up.

J Cardiothorac Surg 2014 Dec 20;9:197. Epub 2014 Dec 20.

Department of Cardiovascular Surgery, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.

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http://dx.doi.org/10.1186/s13019-014-0197-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297443PMC
December 2014

Prostaglandin E2 does not attenuate adrenergic-induced cardiac contractile response.

Naunyn Schmiedebergs Arch Pharmacol 2014 Oct 29;387(10):963-8. Epub 2014 Jun 29.

Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00210-014-1012-2DOI Listing
October 2014

Carvedilol induces greater control of β2- than β 1-adrenoceptor-mediated inotropic and lusitropic effects by PDE3, while PDE4 has no effect in human failing myocardium.

Naunyn Schmiedebergs Arch Pharmacol 2014 Jul 26;387(7):629-40. Epub 2014 Mar 26.

Faculty of Health, QUT, Brisbane; School of Medicine, University of Queensland and Critical Care Research Group, The Prince Charles Hospital, Chermside, QLD, 4032, Australia,

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http://dx.doi.org/10.1007/s00210-014-0974-4DOI Listing
July 2014

Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria.

Cardiovasc Res 2014 Jul 9;103(1):156-67. Epub 2014 May 9.

Danish National Research Foundation Centre for Cardiac Arrhythmia, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.

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http://cardiovascres.oxfordjournals.org/content/cardiovascre
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http://cardiovascres.oxfordjournals.org/cgi/doi/10.1093/cvr/
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http://dx.doi.org/10.1093/cvr/cvu121DOI Listing
July 2014

Attenuated response of L-type calcium current to nitric oxide in atrial fibrillation.

Cardiovasc Res 2014 Mar 12;101(3):533-42. Epub 2013 Dec 12.

Department of Pharmacology and Toxicology, Dresden University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1093/cvr/cvt334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014863PMC
March 2014

Long-term follow-up after aortic valve replacement with Edwards Prima Plus stentless bioprostheses in patients younger than 60 years of age.

J Thorac Cardiovasc Surg 2014 Jan 14;147(1):264-9. Epub 2012 Nov 14.

Clinic for Cardiovascular Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S00225223120133
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http://dx.doi.org/10.1016/j.jtcvs.2012.10.032DOI Listing
January 2014

Atrial-selective antiarrhythmic activity by vernakalant fact or fiction?

Authors:
Torsten Christ

J Cardiovasc Pharmacol 2014 Jan;63(1):23-4

Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1097/FJC.0000000000000024DOI Listing
January 2014

Surgical-transcatheter approach for endocarditis of a calcified aortic homograft.

J Heart Valve Dis 2013 Sep;22(5):751-3

Klinik für Kardiovaskuläre Chirurgie, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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September 2013

The new antiarrhythmic drug vernakalant: ex vivo study of human atrial tissue from sinus rhythm and chronic atrial fibrillation.

Cardiovasc Res 2013 Apr 22;98(1):145-54. Epub 2013 Jan 22.

Department of Pharmacology and Toxicology, Medical Faculty Carl Gustav Carus, Dresden University of Technology, Fetscherstraße 74, Dresden D-01307, Germany.

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http://dx.doi.org/10.1093/cvr/cvt006DOI Listing
April 2013

Sphingosine-1-phosphate induces contraction of valvular interstitial cells from porcine aortic valves.

Cardiovasc Res 2012 Mar 8;93(3):490-7. Epub 2012 Jan 8.

Clinic for Cardiac Surgery, Heart Center Dresden, Technical University Dresden, Fetscherstr. 76, 01307 Dresden, Germany.

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http://dx.doi.org/10.1093/cvr/cvs002DOI Listing
March 2012

Skeletal muscle stem cells propagated as myospheres display electrophysiological properties modulated by culture conditions.

J Mol Cell Cardiol 2011 Feb 29;50(2):357-66. Epub 2010 Oct 29.

Department of Pharmacology and Toxicology, Medical Faculty, University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1016/j.yjmcc.2010.10.011DOI Listing
February 2011

Clinical experience with the ATS 3F stentless aortic bioprosthesis: five years' follow up.

J Heart Valve Dis 2010 Nov;19(6):772-7

Klinik für Kardiovaskuläre Chirurgie, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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November 2010

Inhibition of IK,ACh current may contribute to clinical efficacy of class I and class III antiarrhythmic drugs in patients with atrial fibrillation.

Naunyn Schmiedebergs Arch Pharmacol 2010 Mar 17;381(3):251-9. Epub 2009 Sep 17.

Department of Pharmacology and Toxicology, Dresden University of Technology, Fetscherstr. 74, 01307, Dresden, Germany.

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http://link.springer.com/10.1007/s00210-009-0452-6
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http://dx.doi.org/10.1007/s00210-009-0452-6DOI Listing
March 2010

Tissue slices from adult mammalian hearts as a model for pharmacological drug testing.

Cell Physiol Biochem 2009 4;24(5-6):527-36. Epub 2009 Nov 4.

Department of Pharmacology and Toxicology, University of Technology, Dresden, Germany.

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https://www.karger.com/Article/FullText/257528
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http://dx.doi.org/10.1159/000257528DOI Listing
February 2010

Overestimation of the operative risk by the EuroSCORE also in high-risk patients undergoing aortic valve replacement with a stentless biological prosthesis.

Heart Surg Forum 2010 Feb;13(1):E13-6

Department of Cardiovascular Surgery, Charité Hospital, Medical University, Berlin, Germany. sebastian.holinski@charite

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http://dx.doi.org/10.1532/HSF98.20091071DOI Listing
February 2010

Adult zebrafish heart as a model for human heart? An electrophysiological study.

J Mol Cell Cardiol 2010 Jan 8;48(1):161-71. Epub 2009 Sep 8.

Biotechnology Center and Center for Regenerative Therapies, Dresden University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1016/j.yjmcc.2009.08.034DOI Listing
January 2010

Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts.

Pflugers Arch 2009 Nov;459(1):11-23

The Danish National Research Foundation Centre for Cardiac Arrhythmia (DARC), Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen N, Denmark.

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http://dx.doi.org/10.1007/s00424-009-0718-3DOI Listing
November 2009

Adipocyte fatty acid-binding protein suppresses cardiomyocyte contraction: a new link between obesity and heart disease.

Circ Res 2009 Aug 16;105(4):326-34. Epub 2009 Jul 16.

Medical Clinic III, Dresden University of Technology, Fetscherstr. 74, 01307 Dresden, Germany.

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http://dx.doi.org/10.1161/CIRCRESAHA.109.200501DOI Listing
August 2009

Effects of three metabolites of propiverine on voltage-dependent L-type calcium currents in human atrial myocytes.

Eur J Pharmacol 2008 Nov 3;598(1-3):94-7. Epub 2008 Sep 3.

Department of Pharmacology and Toxicology, Dresden University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1016/j.ejphar.2008.08.035DOI Listing
November 2008

Chelerythrine treatment influences the balance of pro- and anti-apoptotic signaling pathways in the remote myocardium after infarction.

Mol Cell Biochem 2008 Mar 2;310(1-2):119-28. Epub 2007 Dec 2.

Department of Medicine and Cardiology, Dresden University of Technology, Fetscherstr. 76, 01307 Dresden, Germany.

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http://dx.doi.org/10.1007/s11010-007-9672-6DOI Listing
March 2008

Electrophysiological profile of propiverine--relationship to cardiac risk.

Naunyn Schmiedebergs Arch Pharmacol 2008 Feb 19;376(6):431-40. Epub 2007 Dec 19.

Department of Pharmacology and Toxicology, Medical Faculty, Dresden University of Technology, Fetscherstrasse 74, 01307 Dresden, Germany.

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http://link.springer.com/content/pdf/10.1007%2Fs00210-007-02
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http://dx.doi.org/10.1007/s00210-007-0231-1DOI Listing
February 2008

The effects of levosimendan on myocardial function in ropivacaine toxicity in isolated guinea pig heart preparations.

Anesth Analg 2007 Sep;105(3):641-7

Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.

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http://dx.doi.org/10.1213/01.ane.0000278146.15671.03DOI Listing
September 2007

Novel anti-arrhythmic agents for the treatment of atrial fibrillation.

Curr Opin Pharmacol 2007 Apr 15;7(2):214-8. Epub 2007 Feb 15.

Department of Pharmacology and Toxicology, Medical Faculty Carl Gustav Carus, Dresden University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1016/j.coph.2006.10.007DOI Listing
April 2007

5-Azacytidine induces changes in electrophysiological properties of human mesenchymal stem cells.

Cell Res 2006 Dec;16(12):949-60

Department of Pharmacology and Toxicology, Dresden University of Technology, Fetscherstr. 74, D-01307 Dresden, Germany.

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http://dx.doi.org/10.1038/sj.cr.7310116DOI Listing
December 2006

Interaction between autoantibodies against the beta1-adrenoceptor and isoprenaline in enhancing L-type Ca2+ current in rat ventricular myocytes.

J Mol Cell Cardiol 2006 Oct 4;41(4):716-23. Epub 2006 Aug 4.

Department of Pharmacology and Toxicology, Medical Faculty Carl Gustav Carus, Dresden University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1016/j.yjmcc.2006.06.011DOI Listing
October 2006

Carvedilol blocks beta2- more than beta1-adrenoceptors in human heart.

Cardiovasc Res 2006 Jan 12;69(1):128-39. Epub 2005 Oct 12.

Department of Medicine, The Prince Charles Hospital, University of Queensland, Australia.

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http://dx.doi.org/10.1016/j.cardiores.2005.08.024DOI Listing
January 2006

Pharmacodynamics of propiverine and three of its main metabolites on detrusor contraction.

Br J Pharmacol 2005 Jul;145(5):608-19

Institute of Pharmacology and Toxicology, Dresden University of Technology, Fetscherstrasse 74, D-01307 Dresden, Germany.

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http://doi.wiley.com/10.1038/sj.bjp.0706244
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http://dx.doi.org/10.1038/sj.bjp.0706244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1576185PMC
July 2005

Effects of immunoglobulin G from patients with dilated cardiomyopathy on rat cardiomyocytes.

Basic Clin Pharmacol Toxicol 2005 Jun;96(6):445-52

Department of Pharmacology and Toxicology, Medical Faculty, Dresden University of Technology, D-01309 Dresden, Germany.

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http://dx.doi.org/10.1111/j.1742-7843.2005.pto_07.xDOI Listing
June 2005

Risperidone-induced action potential prolongation is attenuated by increased repolarization reserve due to concomitant block of I(Ca,L).

Naunyn Schmiedebergs Arch Pharmacol 2005 May 16;371(5):393-400. Epub 2005 Jun 16.

Department of Pharmacology and Toxicology, Medical Faculty, University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1007/s00210-005-1063-5DOI Listing
May 2005

An aqueous extract of the marine sponge Ectyoplasia ferox stimulates L-type Ca2+-current by direct interaction with the Cav1.2 subunit.

Naunyn Schmiedebergs Arch Pharmacol 2004 Dec 18;370(6):474-83. Epub 2004 Nov 18.

Department of Pharmacology and Toxicology, Dresden University of Technology, Fetscherstrasse 74, 01309 Dresden, Germany.

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http://dx.doi.org/10.1007/s00210-004-0996-4DOI Listing
December 2004

Recording atrial monophasic action potentials using standard pacemaker leads: an alternative way to study electrophysiology properties of the human atrium in vivo?

Pacing Clin Electrophysiol 2004 Dec;27(12):1632-7

Department of Pharmacology and Toxicology, Dresden University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1111/j.1540-8159.2004.00696.xDOI Listing
December 2004

Role of IKur in controlling action potential shape and contractility in the human atrium: influence of chronic atrial fibrillation.

Circulation 2004 Oct 11;110(16):2299-306. Epub 2004 Oct 11.

Department of Pharmacology and Toxicology, Dresden University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1161/01.CIR.0000145155.60288.71DOI Listing
October 2004

Electrophysiological properties of human mesenchymal stem cells.

J Physiol 2004 Feb 24;554(Pt 3):659-72. Epub 2003 Oct 24.

Institut für Pharmakologie und Toxikologie, Medizinische Fakultät Carl Gustav Carus der TU Dresden, Fetscherstrasse 74, D-01307 Dresden, Germany.

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http://doi.wiley.com/10.1113/jphysiol.2003.055806
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1664789PMC
February 2004

Decreased ATP-sensitive K(+) current density during chronic human atrial fibrillation.

J Mol Cell Cardiol 2003 Dec;35(12):1399-405

Department of Pharmacology and Toxicology, Carl Gustav Carus Medical School, Dresden University of Technology, Fetscherstrasse 74, Dresden D 01307, Germany.

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http://dx.doi.org/10.1016/s0022-2828(03)00246-3DOI Listing
December 2003

Rate-adaptive pacing using intracardiac impedance shows no evidence for positive feedback during dobutamine stress test.

Europace 2002 Jul;4(3):311-5

Department of Pharmacology and Toxicology, Medical Faculty, University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1053/eupc.2002.0235DOI Listing
July 2002