Tom D Bunney

Tom D Bunney

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Tom D Bunney

Tom D Bunney

Publications by authors named "Tom D Bunney"

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NMR backbone assignments of the tyrosine kinase domain of human fibroblast growth factor receptor 3 in apo state and in complex with inhibitor PD173074.

Biomol NMR Assign 2018 10 26;12(2):231-235. Epub 2018 Mar 26.

Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.

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http://dx.doi.org/10.1007/s12104-018-9814-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132846PMC
October 2018

Disease Variants of FGFR3 Reveal Molecular Basis for the Recognition and Additional Roles for Cdc37 in Hsp90 Chaperone System.

Structure 2018 03 22;26(3):446-458.e8. Epub 2018 Feb 22.

Institute of Structural and Molecular Biology, Division of Biosciences, University College London, Gower St, London WC1E 6BT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.str.2018.01.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846801PMC
March 2018

Global Profiling of Huntingtin-associated protein E (HYPE)-Mediated AMPylation through a Chemical Proteomic Approach.

Mol Cell Proteomics 2016 Feb 24;15(2):715-25. Epub 2015 Nov 24.

From the ‡Department of Chemistry, Imperial College London, Exhibition Road, London SW7 2AZ, UK;

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http://dx.doi.org/10.1074/mcp.O115.054429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739684PMC
February 2016

Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1.

Adv Biol Regul 2016 Jan 26;60:6-13. Epub 2015 Sep 26.

Institute of Structural and Molecular Biology, Division of Biosciences, University College London, Gower St, London WC1E 6BT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jbior.2015.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739061PMC
January 2016

Crystal structure of the human, FIC-domain containing protein HYPE and implications for its functions.

Structure 2014 Dec;22(12):1831-1843

Division of Biosciences, Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.str.2014.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342408PMC
December 2014

Dysfunction of phospholipase Cγ in immune disorders and cancer.

Trends Biochem Sci 2014 Dec 30;39(12):603-11. Epub 2014 Oct 30.

Institute of Structural and Molecular Biology, Division of Biosciences, University College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.tibs.2014.09.004DOI Listing
December 2014

PLC regulation: emerging pictures for molecular mechanisms.

Trends Biochem Sci 2011 Feb 1;36(2):88-96. Epub 2010 Oct 1.

The Institute of Cancer Research, Section for Cell and Molecular Biology, Chester Beatty Laboratories, Fulham Road, London SW3 6JB, UK.

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http://dx.doi.org/10.1016/j.tibs.2010.08.003DOI Listing
February 2011

Phosphoinositide signalling in cancer: beyond PI3K and PTEN.

Nat Rev Cancer 2010 May;10(5):342-52

The Institute of Cancer Research, Section for Cell and Molecular Biology, Chester Beatty Laboratories, Fulham Road, London SW3 6JB, UK.

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http://www.nature.com/articles/nrc2842
Publisher Site
http://dx.doi.org/10.1038/nrc2842DOI Listing
May 2010

Regulatory links between PLC enzymes and Ras superfamily GTPases: signalling via PLCepsilon.

Adv Enzyme Regul 2009 ;49(1):54-8

Cancer Research UK Centre for Cell and Molecular Biology Chester Beatty Laboratories, The Institute of Cancer Research, Fulham Road, London SW36JB, UK.

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http://dx.doi.org/10.1016/j.advenzreg.2009.01.004DOI Listing
September 2009

Characterization of phospholipase C gamma enzymes with gain-of-function mutations.

J Biol Chem 2009 Aug 16;284(34):23083-93. Epub 2009 Jun 16.

Section of Cell and Molecular Biology, Chester Beatty Laboratories, The Institute of Cancer Research, London SW3 6JB, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M109.019265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755714PMC
August 2009

In vitro reconstitution of activation of PLCepsilon by Ras and Rho GTPases.

Methods Mol Biol 2009 ;462:379-89

Cancer Research UK Centre for Cell and Molecular Biology, Chester Beatty Laboratories, The Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.1007/978-1-60327-115-8_24DOI Listing
February 2009

Characterization of interactions of adapter protein RAPL/Nore1B with RAP GTPases and their role in T cell migration.

J Biol Chem 2007 Oct 23;282(42):30629-42. Epub 2007 Aug 23.

Cancer Research UK Centre for Cell and Molecular Biology, Chester Beatty Laboratories, The Institute of Cancer Research, Fulham Road, London SW3 6JB, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M704361200DOI Listing
October 2007

14-3-3 adaptor proteins are intermediates in ABA signal transduction during barley seed germination.

Plant J 2007 Jan;49(2):289-301

Department of Structural Biology, Faculty of Earth and Life Sciences, Vrije Universiteit, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1365-313X.2006.02955.xDOI Listing
January 2007

Phospholipase C epsilon: linking second messengers and small GTPases.

Trends Cell Biol 2006 Dec 7;16(12):640-8. Epub 2006 Nov 7.

Cancer Research UK Centre for Cell and Molecular Biology, Chester Beatty Laboratories, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK.

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http://dx.doi.org/10.1016/j.tcb.2006.10.007DOI Listing
December 2006

Structural and mechanistic insights into ras association domains of phospholipase C epsilon.

Mol Cell 2006 Feb;21(4):495-507

Cancer Research UK Centre for Cell and Molecular Biology, Chester Beatty Laboratories, The Institute of Cancer Research, Fulham Road, London SW3 6JB, United Kingdom.

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http://dx.doi.org/10.1016/j.molcel.2006.01.008DOI Listing
February 2006

Single amino acid variation in barley 14-3-3 proteins leads to functional isoform specificity in the regulation of nitrate reductase.

Plant J 2005 Dec;44(6):1001-9

Department of Developmental Genetics, De Boelelaan 1085, 1081 HV Amsterdam, the Netherlands.

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http://dx.doi.org/10.1111/j.1365-313X.2005.02599.xDOI Listing
December 2005

Signaling properties and expression in normal and tumor tissues of two phospholipase C epsilon splice variants.

Oncogene 2005 Jan;24(1):90-100

Cancer Research UK Centre for Cell and Molecular Biology, Chester Beatty Laboratories, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK.

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http://dx.doi.org/10.1038/sj.onc.1208168DOI Listing
January 2005

RalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activity.

EMBO J 2005 Jan 9;24(1):54-62. Epub 2004 Dec 9.

Oncogene Team, Cancer Research UK Centre for Cell and Molecular Biology, Chester Beatty Laboratories, Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.1038/sj.emboj.7600497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC544910PMC
January 2005

Fusicoccin signaling reveals 14-3-3 protein function as a novel step in left-right patterning during amphibian embryogenesis.

Development 2003 Oct 20;130(20):4847-58. Epub 2003 Aug 20.

Vrije Universiteit, Faculty of Earth and Life Sciences, Department of Developmental Genetics, Section Molecular Plant Physiology and Biophysics, De Boelelaan 1085, 1081 HV, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1242/dev.00698DOI Listing
October 2003

14-3-3 protein regulation of proton pumps and ion channels.

Plant Mol Biol 2002 Dec;50(6):1041-51

Department of Developmental Genetics, Faculty of Earth and Life Sciences, Vrije Universiteit, De Boelelaan 1087, 1081 HV Amsterdam, Netherlands.

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http://dx.doi.org/10.1023/a:1021231805697DOI Listing
December 2002