Thomas K Waddell

Thomas K Waddell

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Thomas K Waddell

Publications by authors named "Thomas K Waddell"

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Mesenchymal stromal cell therapy during ex vivo lung perfusion ameliorates ischemia-reperfusion injury in lung transplantation.

J Heart Lung Transplant 2019 Nov 26;38(11):1214-1223. Epub 2019 Jul 26.

Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2019.07.006DOI Listing
November 2019

MRI method for labeling and imaging decellularized extracellular matrix scaffolds for tissue engineering.

Magn Reson Med 2019 Nov 14. Epub 2019 Nov 14.

Institute of Biomaterials & Biomedical Engineering, University of Toronto, Canada.

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http://dx.doi.org/10.1002/mrm.28072DOI Listing
November 2019

Donor prone positioning protects lungs from injury during warm ischemia.

Am J Transplant 2019 Oct 25;19(10):2746-2755. Epub 2019 Apr 25.

Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/ajt.15363DOI Listing
October 2019

Preoperative ECMO and plasmapheresis for urgent pulmonary endarterectomy in HIT positive patient.

Ann Thorac Surg 2019 Oct 4. Epub 2019 Oct 4.

Division of Thoracic Surgery, University Health Network, University of Toronto. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2019.08.092DOI Listing
October 2019

Normothermic ex vivo lung perfusion: Does the indication impact organ utilization and patient outcomes after transplantation?

J Thorac Cardiovasc Surg 2019 Sep 9. Epub 2019 Sep 9.

Toronto Lung Transplant Program, University Health Network, Toronto, Ontario, Canada; Division of Thoracic Surgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jtcvs.2019.06.123DOI Listing
September 2019

De-epithelialization of porcine tracheal allografts as an approach for tracheal tissue engineering.

Sci Rep 2019 Aug 19;9(1):12034. Epub 2019 Aug 19.

Latner Thoracic Surgery Research Laboratories, Division of Thoracic Surgery, University Health Network, 101 College St., Toronto, ON, M5G 1L7, Canada.

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http://dx.doi.org/10.1038/s41598-019-48450-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700109PMC
August 2019

3D Models in the Diagnosis of Subglottic Airway Stenosis.

Ann Thorac Surg 2019 06 27;107(6):1860-1865. Epub 2019 Feb 27.

Division of Thoracic Surgery, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.athoracsur.2019.01.045DOI Listing
June 2019

Conversion of human and mouse fibroblasts into lung-like epithelial cells.

Sci Rep 2019 Jun 21;9(1):9027. Epub 2019 Jun 21.

Program in Developmental & Stem Cell Biology, SickKids Research Institute, Hospital for Sick Children, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/s41598-019-45195-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588580PMC
June 2019

CT-guided Microcoil Pulmonary Nodule Localization prior to Video-assisted Thoracoscopic Surgery: Diagnostic Utility and Recurrence-Free Survival.

Radiology 2019 04 5;291(1):214-222. Epub 2019 Feb 5.

From the Divisions of Cardiothoracic Imaging (J.C.L.R., K.H., J.K., T.B.C., M.P., E.T.N.), Thoracic Surgery (A.F.P., T.K.W., S.K., M.C., K.Y.), and Thoracic Pathology (M.C.), Toronto General Hospital, University Health Network, 585 University Ave, Toronto, ON, Canada M5G 2N2; Postgraduate Medical Education, Department of Medical Imaging, University of Toronto, Toronto, Canada (J.C.L.R.); and Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Combe Park, Bath, England, United Kingdom, BA1 3NG (J.C.L.R.).

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http://dx.doi.org/10.1148/radiol.2019181674DOI Listing
April 2019

Porphyrin-High-Density Lipoprotein: A Novel Photosensitizing Nanoparticle for Lung Cancer Therapy.

Ann Thorac Surg 2019 02 11;107(2):369-377. Epub 2018 Oct 11.

Division of Thoracic Surgery, Toronto General Hospital, University Health Network, Toronto, Ontario; Department of Medical Biophysics, University of Toronto, Toronto, Ontario; Guided Therapeutics, Princess Margaret Cancer Centre and TECHNA Institute, University Health Network, Toronto, Ontario; Institute of Biomaterial and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00034975183146
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http://dx.doi.org/10.1016/j.athoracsur.2018.08.053DOI Listing
February 2019

Intraoperative extracorporeal support during lung transplantation in patients bridged with venovenous extracorporeal membrane oxygenation.

J Heart Lung Transplant 2018 12 5;37(12):1418-1424. Epub 2018 Sep 5.

Toronto Lung Transplant Program, Division of Thoracic Surgery, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10532498183154
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http://dx.doi.org/10.1016/j.healun.2018.07.003DOI Listing
December 2018

Emergency department use is high after esophagectomy and feeding tube problems are the biggest culprit.

J Thorac Cardiovasc Surg 2018 12 7;156(6):2340-2348. Epub 2018 Sep 7.

Division of Thoracic Surgery, University of Toronto, Toronto, Ontario, Canada; Division of Thoracic Surgery, Toronto General Hospital, Toronto, Ontario, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S00225223183232
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http://dx.doi.org/10.1016/j.jtcvs.2018.07.100DOI Listing
December 2018

Optimal biomaterials for tracheal epithelial grafts: An in vitro systematic comparative analysis.

Acta Biomater 2018 11 27;81:146-157. Epub 2018 Sep 27.

Institute for Biomaterials and Biomedical Engineering, University of Toronto, 164 College Street, Toronto, Ontario M5S 3G9, Canada; Latner Thoracic Surgery Research Laboratories and the McEwen Centre for Regenerative Medicine, Toronto General Hospital, 101 College St, Toronto, ON M5G 1L7, Canada; Institute of Medical Science, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S17427061183057
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http://dx.doi.org/10.1016/j.actbio.2018.09.048DOI Listing
November 2018

Medium and long-term emergency department utilization after oesophagectomy: a population-based analysis.

Eur J Cardiothorac Surg 2018 10;54(4):683-688

Division of Thoracic Surgery, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1093/ejcts/ezy155DOI Listing
October 2018

Metachronous or synchronous primary lung cancer in the era of computed tomography surveillance.

J Thorac Cardiovasc Surg 2018 Oct 6. Epub 2018 Oct 6.

Division of Thoracic Surgery, Department of Surgery, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00225223183255
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http://dx.doi.org/10.1016/j.jtcvs.2018.09.052DOI Listing
October 2018

Interrupted reprogramming of alveolar type II cells induces progenitor-like cells that ameliorate pulmonary fibrosis.

NPJ Regen Med 2018 4;3:14. Epub 2018 Sep 4.

1Division of Thoracic Surgery, Toronto General Hospital Research Institute, University Health Network, University of Toronto, Toronto, ON Canada.

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http://www.nature.com/articles/s41536-018-0052-5
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http://dx.doi.org/10.1038/s41536-018-0052-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123410PMC
September 2018

Towards donor lung recovery-gene expression changes during ex vivo lung perfusion of human lungs.

Am J Transplant 2018 06 30;18(6):1518-1526. Epub 2018 Mar 30.

Toronto Lung Transplant Program, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/ajt.14700DOI Listing
June 2018

Effects of Warm Versus Cold Ischemic Donor Lung Preservation on the Underlying Mechanisms of Injuries During Ischemia and Reperfusion.

Transplantation 2018 05;102(5):760-768

Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/TP.0000000000002140DOI Listing
May 2018

Extracorporeal life support as a bridge to lung transplantation-experience of a high-volume transplant center.

J Thorac Cardiovasc Surg 2018 03 22;155(3):1316-1328.e1. Epub 2017 Nov 22.

Toronto Lung Transplant Program, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jtcvs.2017.09.161DOI Listing
March 2018

Design of biomimetic substrates for long-term maintenance of alveolar epithelial cells.

Biomater Sci 2018 Jan;6(2):292-303

Institute of Biomaterials & Biomedical Engineering, University of Toronto, 200 College St., Toronto, ON M5S 3E5, Canada.

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http://dx.doi.org/10.1039/c7bm00647kDOI Listing
January 2018

Generation of Induced Progenitor-like Cells from Mature Epithelial Cells Using Interrupted Reprogramming.

Stem Cell Reports 2017 12 30;9(6):1780-1795. Epub 2017 Nov 30.

Division of Thoracic Surgery, Toronto General Hospital Research Institute, University Health Network, University of Toronto, Toronto, ON M5G 2C4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.10.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785620PMC
December 2017

Safety and Efficacy of Ex Vivo Donor Lung Adenoviral IL-10 Gene Therapy in a Large Animal Lung Transplant Survival Model.

Hum Gene Ther 2017 09 4;28(9):757-765. Epub 2017 Jan 4.

1 Latner Thoracic Surgery Research Laboratories, Toronto General Research Institute, University Health Network , Toronto, Ontario, Canada.

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http://dx.doi.org/10.1089/hum.2016.070DOI Listing
September 2017

Skin-derived precursors from human subjects with Type 2 diabetes yield dysfunctional vascular smooth muscle cells.

Clin Sci (Lond) 2017 Aug 5;131(15):1801-1814. Epub 2017 Jul 5.

Toronto General Hospital Research Institute, University Health Network, Toronto, Canada

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http://dx.doi.org/10.1042/CS20170239DOI Listing
August 2017

A novel minimally invasive near-infrared thoracoscopic localization technique of small pulmonary nodules: A phase I feasibility trial.

J Thorac Cardiovasc Surg 2017 08 13;154(2):702-711. Epub 2017 Apr 13.

Division of Thoracic Surgery, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada; TECHNA Institute, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jtcvs.2017.03.140DOI Listing
August 2017

High Risk for Thoracotomy but not Thoracoscopic Lobectomy.

Ann Thorac Surg 2017 Jun 3;103(6):1730-1735. Epub 2017 Mar 3.

Division of Thoracic Surgery, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.athoracsur.2016.11.076DOI Listing
June 2017

Invasive Mediastinal Staging Guideline Concordance.

Ann Thorac Surg 2017 Jun 3;103(6):1736-1741. Epub 2017 Mar 3.

Division of Thoracic Surgery, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.athoracsur.2016.12.010DOI Listing
June 2017

Higher M30 and high mobility group box 1 protein levels in ex vivo lung perfusate are associated with primary graft dysfunction after human lung transplantation.

J Heart Lung Transplant 2017 Jun 21. Epub 2017 Jun 21.

Latner Thoracic Surgery Research Laboratories, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2017.06.005DOI Listing
June 2017

Metabolic heterogeneity of idiopathic pulmonary fibrosis: a metabolomic study.

BMJ Open Respir Res 2017 5;4(1):e000183. Epub 2017 Jun 5.

Department of Thoracic Surgery, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1136/bmjresp-2017-000183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531310PMC
June 2017

Lung Lavage and Surfactant Replacement During Ex Vivo Lung Perfusion for Treatment of Gastric Acid Aspiration-Induced Donor Lung Injury.

J Heart Lung Transplant 2017 May 1;36(5):577-585. Epub 2016 Dec 1.

Latner Thoracic Surgery Research Laboratories, Toronto General Research Institute, University Health Network, and University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2016.11.010DOI Listing
May 2017

The Use of Robotic-Assisted Thoracic Surgery for Lung Resection: A Comprehensive Systematic Review.

Semin Thorac Cardiovasc Surg 2016 9;28(1):182-92. Epub 2016 Feb 9.

Department of Surgery, McMaster University, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1053/j.semtcvs.2016.01.004DOI Listing
April 2017

Evaluation of a New Ultrasound Thoracoscope for Localization of Lung Nodules in Ex Vivo Human Lungs.

Ann Thorac Surg 2017 Mar 17;103(3):926-934. Epub 2016 Oct 17.

Division of Thoracic Surgery, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2016.08.031DOI Listing
March 2017

Surgery and Surgical Consult Rates for Early Stage Lung Cancer in Ontario: A Population-Based Study.

Ann Thorac Surg 2017 Mar 7;103(3):906-910. Epub 2016 Dec 7.

Department of Surgery, University of Toronto, Toronto, Ontario, Canada; Division of Thoracic Surgery, University Health Network, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2016.09.025DOI Listing
March 2017

Partial Restoration of CFTR Function in cftr-Null Mice following Targeted Cell Replacement Therapy.

Mol Ther 2017 03 8;25(3):654-665. Epub 2017 Feb 8.

Latner Thoracic Surgery Research Laboratories and McEwen Centre for Regenerative Medicine, Toronto General Hospital Research Institute, University of Toronto, Toronto, ON M5G 2C4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2016.11.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363215PMC
March 2017

Outcomes after transplantation of lungs preserved for more than 12 h: a retrospective study.

Lancet Respir Med 2017 02 18;5(2):119-124. Epub 2016 Nov 18.

Toronto Lung Transplant Program, Toronto General Hospital, University Health Network, University of Toronto, Toronto, ON, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132600163032
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http://dx.doi.org/10.1016/S2213-2600(16)30323-XDOI Listing
February 2017

Mesenchymal stem cell treatment is associated with decreased perfusate concentration of interleukin-8 during ex vivo perfusion of donor lungs after 18-hour preservation.

J Heart Lung Transplant 2016 10 6;35(10):1245-1254. Epub 2016 May 6.

Toronto Lung Transplant Program, Latner Thoracic Surgery Laboratories, University Health Network, Toronto General Hospital, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2016.04.017DOI Listing
October 2016

Impact of induction therapy on postoperative outcome after extrapleural pneumonectomy for malignant pleural mesothelioma: does induction-accelerated hemithoracic radiation increase the surgical risk?

Eur J Cardiothorac Surg 2016 Sep 22;50(3):433-8. Epub 2016 Mar 22.

Division of Thoracic Surgery, Toronto General Hospital and Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada

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http://dx.doi.org/10.1093/ejcts/ezw074DOI Listing
September 2016

Circulating Cell Death Biomarkers May Predict Survival in Human Lung Transplantation.

Am J Respir Crit Care Med 2016 07;194(1):97-105

1 Latner Thoracic Surgery Research Laboratories, Division of Thoracic Surgery, University of Toronto, Toronto, Canada; and.

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http://dx.doi.org/10.1164/rccm.201510-2115OCDOI Listing
July 2016

Human α1-antitrypsin improves early post-transplant lung function: Pre-clinical studies in a pig lung transplant model.

J Heart Lung Transplant 2016 07 23;35(7):913-21. Epub 2016 Mar 23.

Latner Thoracic Surgery Research Laboratories, Toronto General Research Institute, University Health Network; Institute of Medical Science; Physiology; Surgery, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2016.03.006DOI Listing
July 2016

Modified In Vivo Lung Perfusion for Local Chemotherapy: A Preclinical Study With Doxorubicin.

Ann Thorac Surg 2016 Jun 5;101(6):2132-40. Epub 2016 Mar 5.

Latner Thoracic Surgery Research Laboratories, Toronto General Research Institute; and Division of Thoracic Surgery, Department of Surgery, University of Toronto, University Health Network, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2015.12.043DOI Listing
June 2016

Importance of left atrial pressure during ex vivo lung perfusion.

J Heart Lung Transplant 2016 06 10;35(6):808-14. Epub 2016 Mar 10.

Latner Thoracic Surgery Laboratories, The Toronto Lung Transplant Program, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.healun.2016.02.008DOI Listing
June 2016

Postdischarge venous thromboembolic complications following pulmonary oncologic resection: An underdetected problem.

J Thorac Cardiovasc Surg 2016 Apr 26;151(4):992-9. Epub 2015 Nov 26.

Department of Surgery, McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jtcvs.2015.11.038DOI Listing
April 2016

Annexin V homodimer protects against ischemia reperfusion-induced acute lung injury in lung transplantation.

J Thorac Cardiovasc Surg 2016 Mar 11;151(3):861-869. Epub 2015 Nov 11.

Latner Thoracic Surgery Research Laboratories, Division of Thoracic Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jtcvs.2015.10.112DOI Listing
March 2016

Thoracoscopic ultrasonography for localization of subcentimetre lung nodules.

Eur J Cardiothorac Surg 2016 Feb 7;49(2):690-7. Epub 2015 Apr 7.

Division of Thoracic Surgery, Toronto General Hospital, University Health Network, Toronto, Canada

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http://dx.doi.org/10.1093/ejcts/ezv124DOI Listing
February 2016

Accelerated hemithoracic radiation followed by extrapleural pneumonectomy for malignant pleural mesothelioma.

J Thorac Cardiovasc Surg 2016 Feb 19;151(2):468-73. Epub 2015 Oct 19.

Department of Radiation Oncology, Princess Margaret Cancer Centre and Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jtcvs.2015.09.129DOI Listing
February 2016

Low-dose computed tomography volumetry for subtyping chronic lung allograft dysfunction.

J Heart Lung Transplant 2016 Jan 13;35(1):59-66. Epub 2015 Aug 13.

Latner Thoracic Surgery Research Laboratories, Toronto General Research Institute and Division of Thoracic Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada; Department of Thoracic and Cardiovascular Surgery, Kansai Medical University, Hirakara, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2015.07.005DOI Listing
January 2016

Clinical Utility of Patient-Derived Xenografts to Determine Biomarkers of Prognosis and Map Resistance Pathways in EGFR-Mutant Lung Adenocarcinoma.

J Clin Oncol 2015 Aug 29;33(22):2472-80. Epub 2015 Jun 29.

Erin L. Stewart, Celine Mascaux, Nhu-An Pham, Shingo Sakashita, Jenna Sykes, Lucia Kim, Naoki Yanagawa, Ghassan Allo, Kota Ishizawa, Dennis Wang, Chang-Qi Zhu, Ming Li, Christine Ng, Ni Liu, Melania Pintilie, Petra Martin, Tom John, Igor Jurisica, Natasha B. Leighl, Benjamin G. Neel, Thomas K. Waddell, Frances A. Shepherd, Geoffrey Liu, Ming-Sound Tsao, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada; Lucia Kim, Inha University College of Medicine, Incheon, South Korea; and Tom John, Austin Hospital, Heidelberg, Australia.

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http://jco.ascopubs.org/content/33/22/2472.full.pdf
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http://200.40.135.66:90/toc/0873/2015/0873-20150801-22-09.pd
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.60.1492
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http://dx.doi.org/10.1200/JCO.2014.60.1492DOI Listing
August 2015

En Bloc Resection of Pulmonary Sulcus Non-small Cell Lung Cancer Invading the Spine: A Systematic Literature Review and Pooled Data Analysis.

Ann Surg 2015 Jul;262(1):184-8

*Division of Thoracic Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada †Department of Thoracic, Vascular and Heart-Lung Transplantation Surgery, Hôpital Marie-Lannelongue, Le Plessis Robinson, Paris-Sud University, Orsay, France ‡Department of Thoracic Surgery, Dr. Horst-Schmidt-Klinik, Wiesbaden, Germany §Second Department of Surgery, Kagawa University, Kagawa, Japan.

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https://insights.ovid.com/crossref?an=00000658-201507000-000
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http://dx.doi.org/10.1097/SLA.0000000000000797DOI Listing
July 2015

The role of the endothelin-1 pathway as a biomarker for donor lung assessment in clinical ex vivo lung perfusion.

J Heart Lung Transplant 2015 Jun 16;34(6):849-57. Epub 2015 Jan 16.

Latner Thoracic Surgery Research Laboratories, Toronto General Research Institute; Toronto Lung Transplant Program, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10532498150000
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http://dx.doi.org/10.1016/j.healun.2015.01.003DOI Listing
June 2015

Functional outcomes and quality of life after normothermic ex vivo lung perfusion lung transplantation.

J Heart Lung Transplant 2015 Apr 24;34(4):547-56. Epub 2014 Oct 24.

Toronto Lung Transplant Program, University Health Network, University of Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2014.09.044DOI Listing
April 2015

Outcomes of intraoperative extracorporeal membrane oxygenation versus cardiopulmonary bypass for lung transplantation.

J Thorac Cardiovasc Surg 2015 Apr 21;149(4):1152-7. Epub 2014 Nov 21.

Toronto Lung Transplant Program, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jtcvs.2014.11.039DOI Listing
April 2015

Invited commentary.

Authors:
Thomas K Waddell

Ann Thorac Surg 2015 Apr;99(4):1191-2

Toronto General Hospital, 200 Elizabeth St, 9N-949, Toronto, Ontario, Canada M5G 2C4. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2015.01.009DOI Listing
April 2015

Protein expression profiling predicts graft performance in clinical ex vivo lung perfusion.

Ann Surg 2015 Mar;261(3):591-7

*Toronto Lung Transplant Program, University Health Network; and †Latner Thoracic Surgery Research Laboratories, Toronto General Research Institute, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/SLA.0000000000000974DOI Listing
March 2015

Advances in tracheal reconstruction.

Plast Reconstr Surg Glob Open 2014 Jul 7;2(7):e178. Epub 2014 Aug 7.

Latner Thoracic Surgery Research Laboratories, Division of Thoracic Surgery, University Health Network and McEwen Centre for Regenerative Medicine, Toronto, Ontario, Canada; and Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/GOX.0000000000000097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229282PMC
July 2014

Use of single-cannula venous-venous extracorporeal life support in the management of life-threatening airway obstruction.

Ann Thorac Surg 2015 Mar;99(3):e63-5

Department of Surgery, Division of Thoracic Surgery, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2014.12.033DOI Listing
March 2015

Topographically grooved gel inserts for aligning epithelial cells during air-liquid-interface culture.

Biomater Sci 2015 Jan 9;3(1):121-33. Epub 2014 Sep 9.

Institute of Medical Science, University of Toronto, 200 College St., Toronto, ON M5S 3E5, Canada.

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http://dx.doi.org/10.1039/c4bm00237gDOI Listing
January 2015

A microfluidic device to apply shear stresses to polarizing ciliated airway epithelium using air flow.

Biomicrofluidics 2014 Nov 14;8(6):064104. Epub 2014 Nov 14.

Institute of Biomaterials and Biomedical Engineering, University of Toronto , 200 College St., Toronto, Ontario M5S 3E5, Canada.

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http://dx.doi.org/10.1063/1.4901930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235625PMC
November 2014

Long-term outcome after resection of non-small cell lung cancer invading the thoracic inlet.

Ann Thorac Surg 2014 Sep 25;98(3):962-7. Epub 2014 Jul 25.

Division of Thoracic Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2014.05.015DOI Listing
September 2014

2014 AATS guidelines for the prevention and management of perioperative atrial fibrillation and flutter for thoracic surgical procedures. Executive summary.

J Thorac Cardiovasc Surg 2014 Sep 28;148(3):772-91. Epub 2014 Jun 28.

Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.

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http://dx.doi.org/10.1016/j.jtcvs.2014.06.037DOI Listing
September 2014

Double-chamber rotating bioreactor for dynamic perfusion cell seeding of large-segment tracheal allografts: comparison to conventional static methods.

Tissue Eng Part C Methods 2014 Aug 5;20(8):681-92. Epub 2014 Mar 5.

1 Latner Thoracic Surgery Research Laboratories, Division of Thoracic Surgery, University Health Network , Toronto, Canada .

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http://dx.doi.org/10.1089/ten.TEC.2013.0627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115681PMC
August 2014

Advances in tracheal reconstruction.

Plast Reconstr Surg Glob Open 2014 Jul 7;2(7):e178. Epub 2014 Aug 7.

Latner Thoracic Surgery Research Laboratories, Division of Thoracic Surgery, University Health Network and McEwen Centre for Regenerative Medicine, Toronto, Ontario, Canada; and Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/GOX.0000000000000097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229282PMC
July 2014

Thoracic aortic endografting facilitates the resection of tumors infiltrating the aorta.

J Thorac Cardiovasc Surg 2014 Apr 2;147(4):1178-82; discussion 1182. Epub 2014 Jan 2.

Division of Thoracic Surgery, Sprott Department of Surgery, Toronto General Hospital, University Health Network and the University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jtcvs.2013.12.020DOI Listing
April 2014

Challenges and opportunities for tissue-engineering polarized epithelium.

Tissue Eng Part B Rev 2014 Feb 27;20(1):56-72. Epub 2013 Jul 27.

1 Department of Chemical Engineering and Applied Chemistry, University of Toronto , Toronto, ON, Canada .

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http://dx.doi.org/10.1089/ten.TEB.2013.0144DOI Listing
February 2014

Modified in vivo lung perfusion allows for prolonged perfusion without acute lung injury.

J Thorac Cardiovasc Surg 2014 Feb 27;147(2):774-81: discussion 781-2. Epub 2013 Nov 27.

Latner Thoracic Surgery Laboratories, Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada; Department of Surgery, Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jtcvs.2013.10.009DOI Listing
February 2014

Minimal-dose computed tomography is superior to chest x-ray for the follow-up and treatment of patients with resected lung cancer.

J Thorac Cardiovasc Surg 2014 Jan 18;147(1):30-3. Epub 2013 Oct 18.

Division of Thoracic Surgery, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jtcvs.2013.08.060DOI Listing
January 2014

Long-term outcome after en bloc resection of non-small-cell lung cancer invading the pulmonary sulcus and spine.

J Thorac Oncol 2013 Dec;8(12):1538-44

Divisions of *Thoracic Surgery, †Orthopedic Surgery, ‡Medical Oncology, §Radiation Oncology, and ‖Pathology, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/01.JTO.0000437419.31348.a4DOI Listing
December 2013

Reply to Baisi et al.

Eur J Cardiothorac Surg 2013 Oct 5;44(4):772. Epub 2013 Apr 5.

Department of Thoracic Surgery, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1093/ejcts/ezt194DOI Listing
October 2013

Mesenchymal stromal cells augment CD4+ and CD8+ T-cell proliferation through a CCL2 pathway.

Cytotherapy 2013 Oct 9;15(10):1195-207. Epub 2013 Jul 9.

Latner Thoracic Surgery Research Laboratories, Division of Thoracic Surgery, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jcyt.2013.05.009DOI Listing
October 2013

Bone marrow-derived progenitor cells in end-stage lung disease patients.

BMC Pulm Med 2013 Aug 3;13:48. Epub 2013 Aug 3.

Latner Thoracic Surgery Research Laboratories, Division of Thoracic Surgery, Toronto General Hospital, University Health Network, University of Toronto, North Wing, 9N - 949, 200 Elizabeth Street, Toronto, ON M5G 2C4, Canada.

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http://dx.doi.org/10.1186/1471-2466-13-48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750607PMC
August 2013

The effect of decellularization of tracheal allografts on leukocyte infiltration and of recellularization on regulatory T cell recruitment.

Biomaterials 2013 Jul 8;34(23):5821-32. Epub 2013 May 8.

Latner Thoracic Surgery Research Laboratories, Division of Thoracic Surgery, University Health Network and McEwen Centre for Regenerative Medicine, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.biomaterials.2013.04.044DOI Listing
July 2013

Is video-assisted lobectomy for non-small-cell lung cancer oncologically equivalent to open lobectomy?

Eur J Cardiothorac Surg 2013 Jun 8;43(6):1121-5. Epub 2013 Jan 8.

Department of Thoracic Surgery, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1093/ejcts/ezs623DOI Listing
June 2013

Bone marrow cells expressing clara cell secretory protein increase epithelial repair after ablation of pulmonary clara cells.

Mol Ther 2013 Jun 23;21(6):1251-8. Epub 2013 Apr 23.

Division of Thoracic Surgery, Latner Thoracic Surgery Research Laboratories and McEwen Centre for Regenerative Medicine, University of Toronto, Toronto General Hospital, Toronto Medical Discovery Tower, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/mt.2013.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677308PMC
June 2013

Time-dependent changes in the risk of death in pure bronchiolitis obliterans syndrome (BOS).

J Heart Lung Transplant 2013 May 22;32(5):484-91. Epub 2013 Feb 22.

Toronto Lung Transplant Program, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.healun.2013.01.1054DOI Listing
May 2013

Progression pattern of restrictive allograft syndrome after lung transplantation.

J Heart Lung Transplant 2013 Jan;32(1):23-30

Toronto Lung Transplant Program, University Health Network, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.healun.2012.09.026DOI Listing
January 2013

Experience with the first 50 ex vivo lung perfusions in clinical transplantation.

J Thorac Cardiovasc Surg 2012 Nov 31;144(5):1200-6. Epub 2012 Aug 31.

Toronto Lung Transplant Program, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jtcvs.2012.08.009DOI Listing
November 2012

Engineering airway epithelium.

J Biomed Biotechnol 2012 8;2012:982971. Epub 2012 Feb 8.

Latner Thoracic Surgery Research Laboratories, McEwen Centre for Regenerative Medicine, Toronto General Hospital, Toronto, ON, Canada M5G 2C4.

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http://dx.doi.org/10.1155/2012/982971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304574PMC
October 2012

MicroRNA expression profiling of esophageal cancer before and after induction chemoradiotherapy.

Ann Thorac Surg 2012 Oct 29;94(4):1094-102; discussion 1102-3. Epub 2012 Aug 29.

Division of Thoracic Surgery, St. Joseph's Health Centre, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.athoracsur.2012.04.145DOI Listing
October 2012

Physiologic assessment of the ex vivo donor lung for transplantation.

J Heart Lung Transplant 2012 Oct;31(10):1120-6

Latner Thoracic Surgery Research Laboratories, McEwen Centre for Regenerative Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.healun.2012.08.016DOI Listing
October 2012

Ex vivo adenoviral vector gene delivery results in decreased vector-associated inflammation pre- and post-lung transplantation in the pig.

Mol Ther 2012 Jun 27;20(6):1204-11. Epub 2012 Mar 27.

Latner Thoracic Surgery Research Laboratories, Toronto General Research Institute, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/mt.2012.57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369301PMC
June 2012

Rejection of tracheal allograft by intrapulmonary lymphoid neogenesis in the absence of secondary lymphoid organs.

Transplantation 2012 Jun;93(12):1212-20

Latner Thoracic Surgery Research Laboratories, Toronto General Research Institute, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/TP.0b013e318250fbf5DOI Listing
June 2012