Theo Rispens

Theo Rispens

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Theo Rispens

Theo Rispens

Publications by authors named "Theo Rispens"

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Antidrug antibody detection for adalimumab depends on the type of assay used: an experimental approach to help clinicians interpret diagnostic data.

Clin Exp Rheumatol 2019 Sep-Oct;37(5):756-761. Epub 2019 Mar 18.

Amsterdam Rheumatology and immunology Center, location Reade, and Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Academic Medical Center, Amsterdam, the Netherlands.

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October 2019

Vedolizumab Induces Endoscopic and Histologic Remission in Patients With Crohn's Disease.

Gastroenterology 2019 10 5;157(4):997-1006.e6. Epub 2019 Jun 5.

Amsterdam UMC, University of Amsterdam, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.05.067DOI Listing
October 2019

Pharmacodynamic assessment of cell-bound natalizumab on PBMC samples stored in liquid nitrogen.

J Immunol Methods 2019 Oct 12;473:112632. Epub 2019 Jul 12.

Department of Immunopathology, Sanquin Research, Amsterdam, the Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jim.2019.07.004DOI Listing
October 2019

IgG Glyco-Engineering to Improve IVIg Potency.

Front Immunol 2018 23;9:2442. Epub 2018 Oct 23.

Sanquin Research and Landsteiner Laboratory, Department of Blood Cell Research, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02442
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http://dx.doi.org/10.3389/fimmu.2018.02442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206079PMC
September 2019

The natalizumab wearing-off effect: End of natalizumab cycle; recurrence of MS symptoms.

Neurology 2019 Sep 24. Epub 2019 Sep 24.

From the Amsterdam UMC (Z.L.E.v.K., D.D., I.D., B.I.L.-W., J.K.), Vrije Universiteit Amsterdam; Departments of Neurology (Z.L.E.v.K., D.D., I.D., J.K.) and Radiology & Nuclear Medicine (I.D.), MS Center Amsterdam, Amsterdam Neuroscience; and Departments of Epidemiology and Biostatistics (B.I.L.-W.) and Immunology (A.d.V., I.A.C., A.t.B., T.R.), Landsteiner Laboratory Sanquin Research, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1212/WNL.0000000000008357DOI Listing
September 2019

Does maternal IgG protect infants from allergen-specific IgE sensitization?

J Allergy Clin Immunol 2019 Sep 25. Epub 2019 Sep 25.

Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2019.08.011DOI Listing
September 2019

The effect of certolizumab drug concentration and anti-drug antibodies on TNF neutralisation.

Clin Exp Rheumatol 2019 Aug 30. Epub 2019 Aug 30.

Department of Immunopathology, Sanquin Research, Amsterdam, and Landsteiner Laboratory, Amsterdam UMC, Academic Medical Centre, University of Amsterdam, The Netherlands.

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August 2019

Anti-natalizumab antibodies during 8 years of natalizumab treatment: effect on natalizumab concentration and α4-integrin receptor saturation.

J Neurol 2019 Jul 19;266(7):1804-1805. Epub 2019 Apr 19.

Department of Neurology, Neuroscience Amsterdam, Amsterdam MS Center, Amsterdam University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.

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http://link.springer.com/10.1007/s00415-019-09327-8
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http://dx.doi.org/10.1007/s00415-019-09327-8DOI Listing
July 2019

Human DC-SIGN and CD23 do not interact with human IgG.

Sci Rep 2019 Jul 10;9(1):9995. Epub 2019 Jul 10.

Department Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41598-019-46484-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620288PMC
July 2019

Infusion-related events during natalizumab: No need for post-infusion monitoring.

Mult Scler 2019 Jun 25:1352458519860415. Epub 2019 Jun 25.

Department of Neurology, Amsterdam University Medical Center, Vrije Universiteit Amsterdam, MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1177/1352458519860415DOI Listing
June 2019

Novel Concepts of Altered Immunoglobulin G Galactosylation in Autoimmune Diseases.

Front Immunol 2018 19;9:553. Epub 2018 Mar 19.

Sanquin Research and Landsteiner Laboratory, Department of Experimental Immunohematology, Academic Medical Centre, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2018.00553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867308PMC
May 2019

The enzymatic removal of immunoglobulin variable domain glycans by different glycosidases.

J Immunol Methods 2019 Apr 8;467:58-62. Epub 2019 Feb 8.

Sanquin Research, Department of Immunopathology, Amsterdam, The Netherlands; Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S00221759183043
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http://dx.doi.org/10.1016/j.jim.2019.02.005DOI Listing
April 2019

Biased -Glycosylation Site Distribution and Acquisition across the Antibody V Region during B Cell Maturation.

J Immunol 2019 Apr 8;202(8):2220-2228. Epub 2019 Mar 8.

Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, 1066 CX Amsterdam, the Netherlands.

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http://dx.doi.org/10.4049/jimmunol.1801622DOI Listing
April 2019

Activated T-Follicular Helper 2 Cells Are Associated With Disease Activity in IgG4-Related Sclerosing Cholangitis and Pancreatitis.

Clin Transl Gastroenterol 2019 Apr;10(4):e00020

Peter Medawar Building for Pathogen Research and Oxford NIHR BRC, Nuffield Department of Medicine, University of Oxford, South Parks Road, Oxford, UK.

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http://dx.doi.org/10.14309/ctg.0000000000000020DOI Listing
April 2019

Activated T-Follicular Helper 2 Cells Are Associated With Disease Activity in IgG4-Related Sclerosing Cholangitis and Pancreatitis.

Clin Transl Gastroenterol 2019 Apr 26. Epub 2019 Apr 26.

Peter Medawar Building for Pathogen Research and Oxford NIHR BRC, Nuffield Department of Medicine, University of Oxford, South Parks Road, Oxford, UK.

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http://dx.doi.org/10.14309/ctg.0000000000000020DOI Listing
April 2019

The Ligands for Human IgG and Their Effector Functions.

Antibodies (Basel) 2019 Apr 25;8(2). Epub 2019 Apr 25.

Sanquin Research, Dept Experimental Immunohematology and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.3390/antib8020030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640714PMC
April 2019

ACPA epitopes - what are we actually looking at?

Nat Rev Rheumatol 2019 Mar;15(3):130-132

Department of Immunopathology, Sanquin Research, Amsterdam, Netherlands.

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http://dx.doi.org/10.1038/s41584-018-0157-7DOI Listing
March 2019

On the origin of rheumatoid factors: Insights from analyses of variable region sequences.

Semin Arthritis Rheum 2019 Feb 24;48(4):603-610. Epub 2018 Jun 24.

Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, PO Box 9892, 1006 AN Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2018.06.006DOI Listing
February 2019

Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.

Arthritis Rheumatol 2019 Feb 4;71(2):210-221. Epub 2019 Jan 4.

Karolinska Institutet, Stockholm, Sweden, and Southern Medical University, Guangzhou, China.

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http://dx.doi.org/10.1002/art.40698DOI Listing
February 2019

Defining the Therapeutic Range for Adalimumab and Predicting Response in Psoriasis: A Multicenter Prospective Observational Cohort Study.

J Invest Dermatol 2019 Jan 18;139(1):115-123. Epub 2018 Aug 18.

St John's Institute of Dermatology, School of Basic and Medical Biosciences, Faculty of Life Sciences and Medicine, King's College London, London, UK; St. John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.07.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300405PMC
January 2019

Dynamics of circulating TNF during adalimumab treatment using a drug-tolerant TNF assay.

Sci Transl Med 2019 01;11(477)

Department of Immunopathology, Sanquin Research, 1066 CX Amsterdam, Netherlands, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, Netherlands.

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http://stm.sciencemag.org/lookup/doi/10.1126/scitranslmed.aa
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http://dx.doi.org/10.1126/scitranslmed.aat3356DOI Listing
January 2019

Switching natalizumab to fingolimod within 6 weeks reduces recurrence of disease activity in MS patients.

Mult Scler 2018 10 21;24(11):1453-1460. Epub 2017 Aug 21.

Department of Neurology, Neuroscience Amsterdam, VUmc MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458517726381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174622PMC
October 2018

Restricted immune activation and internalisation of anti-idiotype complexes between drug and antidrug antibodies.

Ann Rheum Dis 2018 10 26;77(10):1471-1479. Epub 2018 Jun 26.

Sanquin Research and Landsteiner Laboratory, Department of Immunopathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2018-213299DOI Listing
October 2018

Unique patterns of glycosylation in immunoglobulin subclass G4-related disease and primary sclerosing cholangitis.

J Gastroenterol Hepatol 2018 Oct 21. Epub 2018 Oct 21.

Sanquin Research, Department of Immunopathology, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1111/jgh.14512
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http://dx.doi.org/10.1111/jgh.14512DOI Listing
October 2018

Clinically relevant discrepancies between different rheumatoid factor assays.

Clin Chem Lab Med 2018 09;56(10):1749-1758

Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1515/cclm-2017-0988DOI Listing
September 2018

Dimeric IgG complexes from IVIg are incapable of inducing in vitro neutrophil degranulation or complement activation.

PLoS One 2018 10;13(4):e0195729. Epub 2018 Apr 10.

Department of Immunopathology, Sanquin Blood Supply and Landsteiner laboratory Amsterdam Medical Centre, University of Amsterdam, CX, Amsterdam, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0195729PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892932PMC
July 2018

Capillary blood microsampling to determine serum biopharmaceutical concentration: Mitra microsampler vs dried blood spot.

Bioanalysis 2018 Jun 4;10(11):815-823. Epub 2018 Jun 4.

Department of Immunopathology, Sanquin Research & Landsteiner Laboratory Academic Medical Centre, 1006 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.4155/bio-2018-0010DOI Listing
June 2018

The majority of natalizumab-treated MS patients have high natalizumab concentrations at time of re-dosing.

Mult Scler 2018 05 9;24(6):805-810. Epub 2017 May 9.

Department of Neurology, Amsterdam Neuroscience, VUmc MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458517708464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971363PMC
May 2018

Response to "Letter to the editor on the paper: The majority of natalizumab-treated MS patients have high natalizumab concentrations at time of re-dosing".

Mult Scler 2018 05 9;24(6):822-823. Epub 2017 Oct 9.

1 Department of Neurology, Amsterdam Neuroscience, VUmc MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458517734073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971362PMC
May 2018

Conserved FcγR- glycan discriminates between fucosylated and afucosylated IgG in humans and mice.

Mol Immunol 2018 02 19;94:54-60. Epub 2017 Dec 19.

Department Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2017.12.006DOI Listing
February 2018

Disease activity following pregnancy-related discontinuation of natalizumab in MS.

Neurol Neuroimmunol Neuroinflamm 2018 Jan 5;5(1):e424. Epub 2017 Dec 5.

Department of Neurology (I.K., Z.L.E.v.K., C.E.L., I.D., C.E.P.v.M., B.A.d.J., B.W.v.O., B.M.J.U., J.K.), Amsterdam Neuroscience, VUmc MS Center Amsterdam, VU University Medical Center; Department of Immunology (T.R.), Landsteiner Laboratory Sanquin Research, Amsterdam; Department of Epidemiology and Biostatistics (B.I.L.-W.), VU University Medical Center; and Department of Radiology & Nuclear Medicine (I.D., M.P.W.), VUmc MS Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1212/NXI.0000000000000424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778770PMC
January 2018

Dried blood spots from finger prick facilitate therapeutic drug monitoring of adalimumab and anti-adalimumab in patients with inflammatory diseases.

Br J Clin Pharmacol 2017 Nov 22;83(11):2474-2484. Epub 2017 Aug 22.

Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Academic Medical Centre Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/bcp.13371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651343PMC
November 2017

Rheumatoid factors do not preferentially bind to ACPA-IgG or IgG with altered galactosylation.

Rheumatology (Oxford) 2017 11;56(11):2025-2030

Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam.

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http://dx.doi.org/10.1093/rheumatology/kex284DOI Listing
November 2017

Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma.

Front Immunol 2017 18;8:1328. Epub 2017 Oct 18.

Department of Immunopathology, Sanquin Research and Landsteiner Laboratory of the Academic Medical Centre, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2017.01328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651247PMC
October 2017

Increases in IgE, Eosinophils, and Mast Cells Can be Used in Diagnosis and to Predict Relapse of IgG4-Related Disease.

Clin Gastroenterol Hepatol 2017 Sep 20;15(9):1444-1452.e6. Epub 2017 Feb 20.

Immunopathology Department, Sanquin, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2017.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592233PMC
September 2017

Drug Efficacy Monitoring in Pharmacotherapy of Multiple Sclerosis With Biological Agents.

Ther Drug Monit 2017 08;39(4):350-355

*Neuroscience Institute Cavalieri Ottolenghi (NICO) and Neurology Department-Centro Riferimento Regionale Sclerosi Multipla (CReSM), San Luigi University Hospital, Turin, Italy; †CNRS, GICC UMR 7292, Université François-Rabelais de Tours, Tours, France; and ‡Sanquin Research and Landsteiner Laboratory, Department of Immunopathology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1097/FTD.0000000000000393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538300PMC
August 2017

Immunogenicity of Therapeutic Antibodies: Monitoring Antidrug Antibodies in a Clinical Context.

Ther Drug Monit 2017 08;39(4):327-332

*Department of Immunopathology, Sanquin Research, Amsterdam, the Netherlands; †Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, the Netherlands; ‡Biologicals Lab, Sanquin Diagnostic Services, Amsterdam, the Netherlands; §Immunology Unit, University Hospital La Paz, Madrid, Spain; and ¶Laboratory for Therapeutic and Diagnostic Antibodies, Campus Gasthuisberg O&N 2, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1097/FTD.0000000000000404DOI Listing
August 2017

Infusion reactions during infliximab treatment are not associated with IgE anti-infliximab antibodies.

Ann Rheum Dis 2017 Jul 28;76(7):1285-1288. Epub 2017 Apr 28.

Department of Immunopathology, Sanquin Research Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2016-211035DOI Listing
July 2017

Affinity of human IgG subclasses to mouse Fc gamma receptors.

MAbs 2017 07 2;9(5):767-773. Epub 2017 May 2.

a Department of Experimental Immunohematology , Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam , The Netherlands.

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http://dx.doi.org/10.1080/19420862.2017.1323159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524164PMC
July 2017

Enhanced Effector Functions Due to Antibody Defucosylation Depend on the Effector Cell Fcγ Receptor Profile.

J Immunol 2017 07 31;199(1):204-211. Epub 2017 May 31.

Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, 1066 CX Amsterdam, the Netherlands.

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http://dx.doi.org/10.4049/jimmunol.1700116DOI Listing
July 2017

Natalizumab-associated progressive multifocal leukoencephalopathy is not preceded by elevated drug concentrations.

Mult Scler 2017 Jun 13;23(7):995-999. Epub 2016 Dec 13.

Department of Neurology, Neuroscience Campus Amsterdam, VUmc MS Center Amsterdam, VU University Medical Center Amsterdam, Amsterdam, The Netherlands.

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http://journals.sagepub.com/doi/10.1177/1352458516684023
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http://dx.doi.org/10.1177/1352458516684023DOI Listing
June 2017

Beyond citrullination: other post-translational protein modifications in rheumatoid arthritis.

Nat Rev Rheumatol 2017 Jun 9;13(6):331-339. Epub 2017 Mar 9.

Department of Rheumatology, C1R, Leiden University Medical Center, Albinusdreef 2, Postbus 9600, 2300 RC Leiden, Netherlands.

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http://dx.doi.org/10.1038/nrrheum.2017.15DOI Listing
June 2017

Neutralizing capacity of monoclonal and polyclonal anti-natalizumab antibodies: The immune response to antibody therapeutics preferentially targets the antigen-binding site.

J Allergy Clin Immunol 2017 03 4;139(3):1035-1037.e6. Epub 2016 Oct 4.

Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.09.014DOI Listing
March 2017

Prevalence of Anti-infliximab Antibodies and Their Associated Co-factors in Children with Refractory Arthritis and/or Uveitis: A Retrospective Longitudinal Cohort Study.

J Rheumatol 2017 03 15;44(3):334-341. Epub 2017 Jan 15.

From the Department of Rheumatology, University Children's Hospital, Zurich; RehaClinic Bad Zurzach, Bad Zurzach; Department of Pediatrics, Ostschweizer Kinderspital, St. Gallen, Switzerland; Laboratory for Biologicals, Sanquin; Department of Immunopathology, Sanquin Research; Landsteiner Academic Medical Centre, Amsterdam, the Netherlands; Department of Pediatrics, Kantonsspital Winterthur, Winterthur, Switzerland.

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http://dx.doi.org/10.3899/jrheum.160072DOI Listing
March 2017

Anti-Hinge Antibodies Recognize IgG Subclass- and Protease-Restricted Neoepitopes.

J Immunol 2017 01 18;198(1):82-93. Epub 2016 Nov 18.

Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, 1066 CX Amsterdam, the Netherlands.

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http://dx.doi.org/10.4049/jimmunol.1601096DOI Listing
January 2017

Room temperature structure of human IgG4-Fc from crystals analysed in situ.

Mol Immunol 2017 01 1;81:85-91. Epub 2016 Dec 1.

King's College London, Randall Division of Cell and Molecular Biophysics, New Hunt's House, London SE1 1UL, United Kingdom; Medical Research Council & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2016.11.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226057PMC
January 2017

Multi-level glyco-engineering techniques to generate IgG with defined Fc-glycans.

Sci Rep 2016 11 22;6:36964. Epub 2016 Nov 22.

Sanquin Research, Department Experimental Immunohematology, Amsterdam, The Netherlands, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/srep36964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131652PMC
November 2016

Therapeutic TNF Inhibitors can Differentially Stabilize Trimeric TNF by Inhibiting Monomer Exchange.

Sci Rep 2016 09 8;6:32747. Epub 2016 Sep 8.

Sanquin Research, Department of Immunopathology and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/srep32747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015024PMC
September 2016

A Tale of 2 Tails: The Interpretation of Changes in Allergen-Specific IgE Following Incidental Allergen Exposure.

J Allergy Clin Immunol Pract 2016 Mar-Apr;4(2):246-7

Division of Research, Department of Immunopathology, Sanquin Blood Supply, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S22132198160000
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http://dx.doi.org/10.1016/j.jaip.2016.01.001DOI Listing
August 2016

Inactivated pepsin inhibits neutrophil activation by Fcgamma-receptor-dependent and independent stimuli.

Clin Immunol 2016 Aug 29;169:85-88. Epub 2016 Jun 29.

Sanquin Research, Department of Immunopathology, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2016.06.008DOI Listing
August 2016

The Immunobiology of Immunoglobulin G4.

Semin Liver Dis 2016 08 28;36(3):200-15. Epub 2016 Jul 28.

Sanquin Research, Department of Immunopathology, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1055/s-0036-1584322DOI Listing
August 2016

Generation and characterization of a unique panel of anti-adalimumab specific antibodies and their application in therapeutic drug monitoring assays.

J Pharm Biomed Anal 2016 Jun 15;125:62-7. Epub 2016 Mar 15.

Laboratory for Therapeutic and Diagnostic Antibodies, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2016.03.029DOI Listing
June 2016

The Developmental History of IgE and IgG4 Antibodies in Relation to Atopy, Eosinophilic Esophagitis, and the Modified TH2 Response.

Curr Allergy Asthma Rep 2016 06;16(6):45

Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, P.O. Box 9190, 1006 AD, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s11882-016-0621-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026408PMC
June 2016

Cross-reactive and pre-existing antibodies to therapeutic antibodies--Effects on treatment and immunogenicity.

MAbs 2015 ;7(4):662-71

a Sanquin Research; Dept. Immunopathology; Amsterdam, The Netherlands; and Landsteiner Laboratory; Academic Medical Centre; University of Amsterdam ; Amsterdam , The Netherlands.

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http://dx.doi.org/10.1080/19420862.2015.1048411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623040PMC
March 2016

Quantification of the degree of biotinylation of proteins using proteinase K digestion and competition ELISA.

J Immunol Methods 2016 Mar 18;430:61-3. Epub 2016 Jan 18.

Sanquin Research, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jim.2016.01.009DOI Listing
March 2016

Using monoclonal antibodies as an international standard for the measurement of anti-adalimumab antibodies.

J Pharm Biomed Anal 2016 Feb 28;120:198-201. Epub 2015 Dec 28.

Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Academic Medical Centre, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2015.12.040DOI Listing
February 2016

The Emerging Importance of IgG Fab Glycosylation in Immunity.

J Immunol 2016 Feb;196(4):1435-41

Department of Rheumatology, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands; and Université Lille, CNRS, UMR 8576, Unité de Glycobiologie Structurale et Fonctionnelle, F 59 000 Lille, France

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http://dx.doi.org/10.4049/jimmunol.1502136DOI Listing
February 2016

On the perplexingly low rate of transport of IgG2 across the human placenta.

PLoS One 2014 24;9(9):e108319. Epub 2014 Sep 24.

Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108319PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177109PMC
December 2015

IgG Subclass Specificity Discriminates Restricted IgM Rheumatoid Factor Responses From More Mature Anti-Citrullinated Protein Antibody-Associated or Isotype-Switched IgA Responses.

Arthritis Rheumatol 2015 Dec;67(12):3124-34

Sanquin Research, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/art.39299DOI Listing
December 2015

Heightened Expression of CD39 by Regulatory T Lymphocytes Is Associated with Therapeutic Remission in Inflammatory Bowel Disease.

Inflamm Bowel Dis 2015 Dec;21(12):2806-14

*Centre for Colorectal Disease, St. Vincent's University Hospital, Dublin and School of Medicine and Medical Science, University College Dublin, Dublin, Ireland; †Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Academic Medical Centre, Amsterdam, The Netherlands; and ‡Division of Gastroenterology, Beth Israel Deaconess Medical School and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1097/MIB.0000000000000566DOI Listing
December 2015

Comparing Tapering Strategy to Standard Dosing Regimen of Tumor Necrosis Factor Inhibitors in Patients with Spondyloarthritis in Low Disease Activity.

J Rheumatol 2015 Sep 15;42(9):1638-46. Epub 2015 Jul 15.

From the La Paz University Hospital, and the Rheumatology Department, La Paz University Hospital-Idipaz, Madrid, Spain; Sanquin Diagnostic Services; Department of Rheumatology, VU University Medical Centre; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam; Jan van Breemen Research Institute|Reade, Amsterdam, the Netherlands.C. Plasencia, MD, Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Academic Medical Centre, Rheumatology Department, La Paz University Hospital-Idipaz; E.L. Kneepkens, MD; G. Wolbink, PhD; C.L. Krieckaert, MD; S. Turk, MD, Jan van Breemen Research Institute|Reade; V. Navarro-Compán, MD, Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Academic Medical Centre, Rheumatology Department, La Paz University Hospital-Idipaz; M. L'Ami, MSc, Jan van Breemen Research Institute|Reade; M.T. Nurmohamed, PhD; I. van der Horst-Bruinsma, PhD, Jan van Breemen Research Institute|Reade and Sanquin Diagnostic Services; T. Jurado, MSC; C. Diego, BSC, La Paz University Hospital; G. Bonilla, MD; A. Villalba, MD; D. Peiteado, MD; L. Nuño, PhD, Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Academic Medical Centre, Rheumatology Department, La Paz University Hospital-Idipaz; D. van der Kleij, PhD, Sanquin Diagnostic Services; T. Rispens, PhD, Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam; E. Martín-Mola, PhD; A. Balsa, PhD, Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Academic Medical Centre, Rheumatology Department, La Paz University Hospital-Idipaz; D. Pascual-Salcedo, PhD, La Paz University Hospital.

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http://dx.doi.org/10.3899/jrheum.141128DOI Listing
September 2015

Loss of Infliximab Into Feces Is Associated With Lack of Response to Therapy in Patients With Severe Ulcerative Colitis.

Gastroenterology 2015 Aug 25;149(2):350-5.e2. Epub 2015 Apr 25.

Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.04.016DOI Listing
August 2015

Hinge-Region O-Glycosylation of Human Immunoglobulin G3 (IgG3).

Mol Cell Proteomics 2015 May 10;14(5):1373-84. Epub 2015 Mar 10.

From the ‡Center for Proteomics and Metabolomics, **Division of BioAnalytical Chemistry, VU University Amsterdam, Amsterdam, The Netherlands

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http://dx.doi.org/10.1074/mcp.M114.047381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424406PMC
May 2015

Systematic comparison of drug-tolerant assays for anti-drug antibodies in a cohort of adalimumab-treated rheumatoid arthritis patients.

J Immunol Methods 2015 Mar 27;418:29-38. Epub 2015 Jan 27.

Sanquin Research, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S00221759150001
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http://dx.doi.org/10.1016/j.jim.2015.01.007DOI Listing
March 2015

Anti-adalimumab antibodies and adalimumab concentrations in psoriatic arthritis; an association with disease activity at 28 and 52 weeks of follow-up.

Ann Rheum Dis 2014 Dec 12;73(12):2178-82. Epub 2014 Aug 12.

Department of Rheumatology, Jan van Breemen Research Institute | Reade, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2014-205554DOI Listing
December 2014

Golimumab trough levels, antidrug antibodies and clinical response in patients with rheumatoid arthritis treated in daily clinical practice.

Ann Rheum Dis 2014 Dec 26;73(12):2217-9. Epub 2014 Sep 26.

Department of Rheumatology, Jan van Breemen Research Institute | Reade, Amsterdam, The Netherlands Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Academic Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/annrheumdis-2014-205983DOI Listing
December 2014

Functional analysis of the anti-adalimumab response using patient-derived monoclonal antibodies.

J Biol Chem 2014 Dec 17;289(50):34482-8. Epub 2014 Oct 17.

From the Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Academic Medical Centre, 1105 AZ Amsterdam, The Netherlands,

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http://dx.doi.org/10.1074/jbc.M114.615500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263856PMC
December 2014

Inhibition of FcγR-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and FcγRIIb in human macrophages.

Blood 2014 Dec 28;124(25):3709-18. Epub 2014 Oct 28.

Department of Blood Cell Research, Emma Children's Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2014-05-576835DOI Listing
December 2014

IgG subclasses and allotypes: from structure to effector functions.

Front Immunol 2014 20;5:520. Epub 2014 Oct 20.

Department of Immunopathology, Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam , Amsterdam , Netherlands.

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http://dx.doi.org/10.3389/fimmu.2014.00520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202688PMC
November 2014

Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages.

Nat Commun 2014 Nov 13;5:5444. Epub 2014 Nov 13.

Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/ncomms6444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243215PMC
November 2014

Antibodies to IgG4 hinge can be found in rheumatoid arthritis patients during all stages of disease and may exacerbate chronic antibody-mediated inflammation.

Arthritis Rheumatol 2014 May;66(5):1133-40

Sanquin Research, Academic Medical Centre, University of Amsterdam, and Jan van Breemen Research Institute | Reade, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1002/art.38335
Publisher Site
http://dx.doi.org/10.1002/art.38335DOI Listing
May 2014