Sophie Vacher

Sophie Vacher

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Sophie Vacher

Sophie Vacher

Publications by authors named "Sophie Vacher"

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Immune gene expression in head and neck squamous cell carcinoma patients.

Eur J Cancer 2019 Oct 5;121:210-223. Epub 2019 Oct 5.

Department of Drug Development and Innovation, Institut Curie, Paris & Saint-Cloud, France; INSERM U900 Research Unit, Institut Curie, Saint-Cloud, France; Versailles-Saint-Quentin-en-Yvelines University, Montigny-le-Bretonneux, France. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.08.028DOI Listing
October 2019

P-cadherin-induced decorin secretion is required for collagen fiber alignment and directional collective cell migration.

J Cell Sci 2019 Oct 11. Epub 2019 Oct 11.

CRBM, Centre de Recherche en Biologie cellulaire de Montpellier, CNRS UMR 5237, 34000 Montpellier, France Montpellier University, 34000 Montpellier, France

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http://dx.doi.org/10.1242/jcs.233189DOI Listing
October 2019

Differential gene expression in growth factors, epithelial mesenchymal transition and chemotaxis in the diffuse type compared with the intestinal type of gastric cancer.

Oncol Lett 2019 Jul 21;18(1):674-686. Epub 2019 May 21.

Department of Genetics, Pharmacogenomics Unit-Institut Curie, University of Paris-Descartes-Paris 5, 75005 Paris, France.

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http://dx.doi.org/10.3892/ol.2019.10392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546989PMC
July 2019

Targeted next-generation sequencing identifies clinically relevant somatic mutations in a large cohort of inflammatory breast cancer.

Breast Cancer Res 2018 08 7;20(1):88. Epub 2018 Aug 7.

Pharmacogenomic Unit, Department of Genetics, Curie Institute, PSL Research University, 26 rue d'Ulm, 75005, Paris, France.

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http://dx.doi.org/10.1186/s13058-018-1007-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081877PMC
August 2018

ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis.

Breast Cancer Res 2018 07 11;20(1):73. Epub 2018 Jul 11.

University of Lille, CNRS, Institut Pasteur de Lille, UMR 8161 - M3T - Mechanisms of Tumorigenesis and Targeted Therapies, F-59000, Lille, France.

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http://dx.doi.org/10.1186/s13058-018-0992-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042225PMC
July 2018

Alterations in the balance of tubulin glycylation and glutamylation in photoreceptors leads to retinal degeneration.

J Cell Sci 2017 03 19;130(5):938-949. Epub 2017 Jan 19.

Institut Curie, PSL Research University, CNRS UMR3348, Orsay F-91405, France

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http://dx.doi.org/10.1242/jcs.199091DOI Listing
March 2017

Gain-of-function Prolactin Receptor Variants Are Not Associated With Breast Cancer and Multiple Fibroadenoma Risk.

J Clin Endocrinol Metab 2016 11 30;101(11):4449-4460. Epub 2016 Aug 30.

Institut E3M-ICAN, Department of Endocrinology and Reproductive Medicine (Z.C., C.C., V.Gr., I.T., P.T.), Hôpitaux Universitaires Pitié Salpêtrière Charles Foix, Centre des Pathologies Gynécologiques Rares, Firendo, Université Pierre et Marie Curie, 75013 Paris, France; Department of Oncological Surgery (F.L.), Institut Curie, 75005 Paris, France; Inserm (M.B., I.C., A.C., N.P., S.B., F.B., P.C., J.-E.G., V.G., P.T.), U1151, Institut Necker Enfants Malades, 75993 Paris, France; Université Paris Descartes (M.B., I.C., A.C., N.P., S.B., F.B., M.F., M.D.C., R.P., J.-E. G., V.G.), Sorbonne Paris Cité, France; Department of Genetics (I.B., S.V.), Institut Curie, 75005 Paris, France; Unite de Recherche Clinique (M.-L.T., A.B.), Pitie Salpêtriere Hospital, 75013 Paris, France; Inserm (M.F., M.D.C.), U1016, Institut Cochin, 75014 Paris, France; CNRS (M.F., M.D.C., R.P.), UMR8104, Paris, France; Inter Régional pour la Santé (F.R., J.T.), La Riche, France; and Department of Pathology (B.S.-Z.), Institut Curie, 75005 Paris, France.

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http://dx.doi.org/10.1210/jc.2016-2372DOI Listing
November 2016

Combination of Carboplatin and Bevacizumab Is an Efficient Therapeutic Approach in Retinoblastoma Patient-Derived Xenografts.

Invest Ophthalmol Vis Sci 2016 Sep;57(11):4916-4926

Laboratory of Preclinical Investigation, Translational Research Department, Paris Sciences et Lettres (PSL) University, Institut Curie, Paris, France 8Department of Medical Oncology, Institut Curie, Paris, France.

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http://dx.doi.org/10.1167/iovs.15-18725DOI Listing
September 2016

Expression of ANRIL-Polycomb Complexes-CDKN2A/B/ARF Genes in Breast Tumors: Identification of a Two-Gene (EZH2/CBX7) Signature with Independent Prognostic Value.

Mol Cancer Res 2016 07 21;14(7):623-33. Epub 2016 Apr 21.

Unit of Pharmacogenomics, Department of Genetics, Curie Institute, Paris, France. Faculty of Pharmaceutical and Biological Sciences, Paris Descartes University, Paris, France.

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http://mcr.aacrjournals.org/cgi/doi/10.1158/1541-7786.MCR-15
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http://dx.doi.org/10.1158/1541-7786.MCR-15-0418DOI Listing
July 2016

Vandetanib as a potential new treatment for estrogen receptor-negative breast cancers.

Int J Cancer 2016 May 6;138(10):2510-21. Epub 2016 Jan 6.

Translational Research Department, Institut Curie, Paris, 75005, France.

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http://dx.doi.org/10.1002/ijc.29974DOI Listing
May 2016

Unraveling the Role of Huntingtin in Breast Cancer Metastasis.

J Natl Cancer Inst 2015 Oct 20;107(10). Epub 2015 Aug 20.

Institut Curie, Paris, France (MST, JRM, CMS, LF, SL, SV, IB, AVS, SH); CNRS UMR 3306, Orsay, France (MST, JRM, CMS, SL, SH); INSERM U1005, Orsay, France (MST, JRM, CMS, SL, SH); University Paris Sud 11, Orsay, France (MST); Apoptosis, Cancer and Development Laboratory, Equipe labellisée 'La Ligue', Centre National de la Recherche Scientifique UMR5238, Université de Lyon, Lyon, France (JF, AB, PM); Department of Biostatistics and Medical Informatics, Assistance Publique-Hôpitaux de Paris (STdM); Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France (STdM); INSERM, UMR_S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France (STdM); University Paris Descartes, Sorbonne Paris Cité, France (IB); Department of Pathology, Institut Curie, Paris, France (AVS); Univ. Grenoble Alpes, Grenoble Institut des Neurosciences, GIN, Grenoble, France (SH); INSERM U836, Grenoble, France (SH).

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http://dx.doi.org/10.1093/jnci/djv208DOI Listing
October 2015

Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data.

Cancer Res 2015 Apr 24;75(8):1560-6. Epub 2015 Feb 24.

IFR71, Faculté de Sciences Biologiques et Pharmaceutiques, Université Paris Descartes, Sorbonne Paris Cité, Paris, France. Recherche Translationnelle, Centre de Recherche, Institut Curie, Paris, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-1590DOI Listing
April 2015

Protein kinase D1 regulates ERα-positive breast cancer cell growth response to 17β-estradiol and contributes to poor prognosis in patients.

J Cell Mol Med 2014 Dec 7;18(12):2536-52. Epub 2014 Oct 7.

Laboratoire de Biologie et de Pharmacologie Appliquée, UMR 8113 CNRS, Ecole Normale Supérieure de Cachan, Cachan, France.

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http://dx.doi.org/10.1111/jcmm.12322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302658PMC
December 2014

Variations in the mRNA expression of poly(ADP-ribose) polymerases, poly(ADP-ribose) glycohydrolase and ADP-ribosylhydrolase 3 in breast tumors and impact on clinical outcome.

Int J Cancer 2013 Dec 9;133(12):2791-800. Epub 2013 Aug 9.

Laboratoire d'Oncogénétique, Institut Curie-Hôpital René Huguenin, 92210, Saint-Cloud, France.

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http://dx.doi.org/10.1002/ijc.28304DOI Listing
December 2013

Quantification of PKC family genes in sporadic breast cancer by qRT-PCR: evidence that PKCι/λ overexpression is an independent prognostic factor.

Int J Cancer 2012 Dec 21;131(12):2852-62. Epub 2012 May 21.

Department of Molecular Biology, National Cancer Institute (NCI-UG), University of Gezira, Wad Medani, Sudan.

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http://dx.doi.org/10.1002/ijc.27600DOI Listing
December 2012

PIK3CA mutation impact on survival in breast cancer patients and in ERα, PR and ERBB2-based subgroups.

Breast Cancer Res 2012 Feb 13;14(1):R28. Epub 2012 Feb 13.

Laboratoire d'Oncogénétique, Institut Curie, Hôpital René Huguenin, 35 Rue Dailly, Saint-Cloud, F-92210, France.

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http://dx.doi.org/10.1186/bcr3113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496146PMC
February 2012

Genome-wide DNA methylation profiling of CpG islands in breast cancer identifies novel genes associated with tumorigenicity.

Cancer Res 2011 Apr 1;71(8):2988-99. Epub 2011 Mar 1.

Medical and Molecular Genetics, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.

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http://cancerres.aacrjournals.org/content/early/2011/04/08/0
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http://cancerres.aacrjournals.org/content/early/2011/02/25/0
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-10-4026DOI Listing
April 2011

Gene expression profiling reveals new aspects of PIK3CA mutation in ERalpha-positive breast cancer: major implication of the Wnt signaling pathway.

PLoS One 2010 Dec 30;5(12):e15647. Epub 2010 Dec 30.

Laboratoire d'Oncogénétique, Institut National de la Santé et de la Recherche, U745, Institut Curie/Hôpital René Huguenin, St-Cloud, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015647PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012715PMC
December 2010

DNA repair gene expression and risk of locoregional relapse in breast cancer patients.

Int J Radiat Oncol Biol Phys 2010 Oct 21;78(2):328-36. Epub 2010 Jan 21.

Department of Radiation Oncology, Centre René Huguenin, Saint Cloud, France.

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http://dx.doi.org/10.1016/j.ijrobp.2009.07.1735DOI Listing
October 2010

NF-kappa B genes have a major role in inflammatory breast cancer.

BMC Cancer 2008 Feb 4;8:41. Epub 2008 Feb 4.

Centre Rene Huguenin, FNCLCC, 35 rue Dailly, 92210, St-Cloud, France.

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http://dx.doi.org/10.1186/1471-2407-8-41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267801PMC
February 2008

CXC chemokines located in the 4q21 region are up-regulated in breast cancer.

Endocr Relat Cancer 2007 Dec;14(4):1039-52

INSERM, U844, Site Saint Eloi-Bat INM, 80, rue Augustin Fliche, Montpellier F-34091, France.

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http://dx.doi.org/10.1677/erc.1.01301DOI Listing
December 2007