Shannon J Turley

Shannon J Turley

UNVERIFIED PROFILE

Are you Shannon J Turley?   Register this Author

Register author
Shannon J Turley

Shannon J Turley

Publications by authors named "Shannon J Turley"

Are you Shannon J Turley?   Register this Author

76Publications

1626Reads

7Profile Views

TGFβ biology in cancer progression and immunotherapy.

Nat Rev Clin Oncol 2020 Jul 24. Epub 2020 Jul 24.

Department of Anatomy, UCSF, San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41571-020-0403-1DOI Listing
July 2020

Lymph node stromal cells: cartographers of the immune system.

Nat Immunol 2020 04 23;21(4):369-380. Epub 2020 Mar 23.

Department of Cancer Immunology, Genentech, South San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41590-020-0635-3DOI Listing
April 2020

Neutrophils Follow Stromal Omens to Limit Peritoneal Inflammation.

Immunity 2020 Apr;52(4):578-580

Department of Cancer Immunology, Genentech, South San Francisco, CA 94080, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2020.03.015DOI Listing
April 2020

Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient.

Cell Stem Cell 2020 03 20;26(3):391-402.e5. Epub 2020 Feb 20.

Department of Medical Oncology and Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02139, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2020.01.008DOI Listing
March 2020

Mechanosensing by Peyer's patch stroma regulates lymphocyte migration and mucosal antibody responses.

Nat Immunol 2019 11 14;20(11):1506-1516. Epub 2019 Oct 14.

Division of Medical Sciences, Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41590-019-0505-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015178PMC
November 2019

A short field guide to fibroblast function in immunity.

Semin Immunol 2018 02 1;35:48-58. Epub 2017 Dec 1.

Department of Cancer Immunology, Genentech, South San Francisco, CA 94080, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.smim.2017.11.001DOI Listing
February 2018

Tumour lymph vessels boost immunotherapy.

Nature 2017 Dec;552(7685):340-342

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/d41586-017-08669-5DOI Listing
December 2017

Tumour lymph vessels boost immunotherapy.

Nature 2017 12;552(7685):340-342

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/d41586-017-08669-5DOI Listing
December 2017

Immunological hallmarks of stromal cells in the tumour microenvironment.

Nat Rev Immunol 2015 Nov 16;15(11):669-82. Epub 2015 Oct 16.

Department of Cancer Immunology, Genentech, 1 DNA Way, South San Francisco, California 94080, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nri3902DOI Listing
November 2015

IgE/FcεRI-Mediated Antigen Cross-Presentation by Dendritic Cells Enhances Anti-Tumor Immune Responses.

Cell Rep 2015 Mar 5;10(9):1487-1495. Epub 2015 Mar 5.

Division of Gastroenterology and Nutrition, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2015.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559493PMC
March 2015

Hepatic immune regulation by stromal cells.

Curr Opin Immunol 2015 Feb 28;32:1-6. Epub 2014 Oct 28.

Cancer Immunology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.coi.2014.10.002DOI Listing
February 2015

Fibroblastic reticular cells: organization and regulation of the T lymphocyte life cycle.

J Immunol 2015 Feb;194(4):1389-94

Department of Cancer Immunology, Genentech, South San Francisco, CA 94080

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1402520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324549PMC
February 2015

The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture.

Nat Immunol 2015 Jan 27;16(1):75-84. Epub 2014 Oct 27.

1] Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. [2] Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA. [3] Department of Cancer Immunology, Genentech, South San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni.3035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270928PMC
January 2015

Stromal infrastructure of the lymph node and coordination of immunity.

Trends Immunol 2015 Jan 9;36(1):30-9. Epub 2014 Dec 9.

Department of Cancer Immunology, Genentech, South San Francisco, CA 94080, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.it.2014.11.003DOI Listing
January 2015

B cell homeostasis and follicle confines are governed by fibroblastic reticular cells.

Nat Immunol 2014 Oct 24;15(10):973-81. Epub 2014 Aug 24.

1] Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, Massachusetts, USA. [2] Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA. [3].

View Article

Download full-text PDF

Source
http://www.nature.com/doifinder/10.1038/ni.2965
Publisher Site
http://dx.doi.org/10.1038/ni.2965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205585PMC
October 2014

Lymph node fibroblastic reticular cell transplants show robust therapeutic efficacy in high-mortality murine sepsis.

Sci Transl Med 2014 Aug;6(249):249ra109

Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Harvard Medical School, and Shriners Hospitals for Children, Boston, MA 02114, USA. Harvard Stem Cell Institute, Cambridge, MA 02138, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scitranslmed.3009377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415170PMC
August 2014

The tumor microenvironment shapes lineage, transcriptional, and functional diversity of infiltrating myeloid cells.

Cancer Immunol Res 2014 Jul 31;2(7):655-67. Epub 2014 Mar 31.

Authors' Affiliations: Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts; Departments of

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2326-6066.CIR-13-0209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194071PMC
July 2014

Chemokine 'grooming' by cLECs directs DC migration.

Nat Immunol 2014 Jul;15(7):595-6

Harvard Medical School, Boston, Massachusetts, USA, the Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, Massachusetts, USA, and the Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni.2926DOI Listing
July 2014

Trans-nodal migration of resident dendritic cells into medullary interfollicular regions initiates immunity to influenza vaccine.

J Exp Med 2014 Jul 21;211(8):1611-21. Epub 2014 Jul 21.

Graduate Program in Immunology, Department of Pediatrics, and Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115Graduate Program in Immunology, Department of Pediatrics, and Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115 The Program in Cellular and Molecular Medicine, Children's Hospital Boston, Boston, MA 02115

View Article

Download full-text PDF

Source
http://www.jem.org/lookup/doi/10.1084/jem.20132327
Publisher Site
http://dx.doi.org/10.1084/jem.20132327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113935PMC
July 2014

Tetraspanin TSPAN12 regulates tumor growth and metastasis and inhibits β-catenin degradation.

Cell Mol Life Sci 2014 Apr 18;71(7):1305-14. Epub 2013 Aug 18.

Cancer Immunology and AIDS, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, 02215, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00018-013-1444-8
Publisher Site
http://dx.doi.org/10.1007/s00018-013-1444-8DOI Listing
April 2014

Stromal and hematopoietic cells in secondary lymphoid organs: partners in immunity.

Immunol Rev 2013 Jan;251(1):160-76

Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/imr.12023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539229PMC
January 2013

How to connect an IgE-driven response with CTL activity?

Cancer Immunol Immunother 2012 Sep 1;61(9):1521-5. Epub 2011 Nov 1.

Division of Gastroenterology and Nutrition, Children's Hospital Boston, 300 Longwood Ave, Enders 630, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/content/pdf/10.1007/s00262-011-1127
Web Search
http://link.springer.com/10.1007/s00262-011-1127-y
Publisher Site
http://dx.doi.org/10.1007/s00262-011-1127-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299812PMC
September 2012

Podoplanin: emerging functions in development, the immune system, and cancer.

Front Immunol 2012 12;3:283. Epub 2012 Sep 12.

Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute Boston, MA, USA ; Division of Medical Sciences, Harvard Medical School Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2012.00283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439854PMC
September 2012

Differential effect of CD69 targeting on bystander and antigen-specific T cell proliferation.

J Leukoc Biol 2012 Jul 27;92(1):145-58. Epub 2012 Apr 27.

Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.1011499DOI Listing
July 2012

Aire controls mesenchymal stem cell-mediated suppression in chronic colitis.

Mol Ther 2012 Jan 27;20(1):178-86. Epub 2011 Sep 27.

Department of Surgery, Center for Engineering in Medicine and Surgical Services, Massachusetts General Hospital, Harvard Medical School and the Shriners Hospitals for Children, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/mt.2011.192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255580PMC
January 2012

Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes.

Nat Immunol 2011 Sep 18;12(11):1096-104. Epub 2011 Sep 18.

Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni.2112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457791PMC
September 2011

Diminished metastasis in tetraspanin CD151-knockout mice.

Blood 2011 Jul 2;118(2):464-72. Epub 2011 May 2.

Dana-Farber Cancer Institute, Boston, MA 02215-5450, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2010-08-302240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138696PMC
July 2011

Self-antigen presentation by dendritic cells and lymphoid stroma and its implications for autoimmunity.

Curr Opin Immunol 2011 Feb 16;23(1):138-45. Epub 2010 Dec 16.

Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.coi.2010.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042528PMC
February 2011

Lymph node stroma broaden the peripheral tolerance paradigm.

Trends Immunol 2011 Jan 10;32(1):12-8. Epub 2010 Dec 10.

Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S14714906100016
Publisher Site
http://dx.doi.org/10.1016/j.it.2010.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163075PMC
January 2011

The stromal and haematopoietic antigen-presenting cells that reside in secondary lymphoid organs.

Nat Rev Immunol 2010 Dec 19;10(12):813-25. Epub 2010 Nov 19.

Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nri2886
Publisher Site
http://dx.doi.org/10.1038/nri2886DOI Listing
December 2010

Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15Ralpha complexes.

Proc Natl Acad Sci U S A 2010 Dec 22;107(50):21647-52. Epub 2010 Nov 22.

Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, MA 02115.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1012128107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003106PMC
December 2010

Complement-dependent transport of antigen into B cell follicles.

J Immunol 2010 Sep;185(5):2659-64

The Immune Disease Institute and Program in Cellular and Molecular Medicine, Children's Hospital, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1000522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477863PMC
September 2010

Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes.

Nat Immunol 2010 May 21;11(5):427-34. Epub 2010 Mar 21.

The Immune Disease Institute and Program in Cellular and Molecular Medicine, Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni.1856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424101PMC
May 2010

AIRE in the thymus and beyond.

Curr Opin Immunol 2009 Dec 14;21(6):582-9. Epub 2009 Oct 14.

Diabetes Center and the Department of Medicine, University of California, San Francisco, CA 94143-0540, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.coi.2009.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787634PMC
December 2009

Unconventional antigen-presenting cells in the induction of peripheral CD8(+) T cell tolerance.

J Leukoc Biol 2009 Oct 3;86(4):795-801. Epub 2009 Aug 3.

Division of Medical Sciences and Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.0509362DOI Listing
October 2009

Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes.

Nat Immunol 2009 Sep 9;10(9):1026-33. Epub 2009 Aug 9.

Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni.1773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752139PMC
September 2009

Peripheral tolerance induction by lymph node stroma.

Adv Exp Med Biol 2009 ;633:113-27

Department of Pathology, Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/content/pdf/10.1007/978-0-387-79311
Web Search
http://dx.doi.org/10.1007/978-0-387-79311-5_10DOI Listing
May 2009

Immunology. Chaperone puts the brakes on.

Science 2008 Dec;322(5908):1640-1

Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1168103DOI Listing
December 2008

Direct presentation of antigen by lymph node stromal cells protects against CD8 T-cell-mediated intestinal autoimmunity.

Gastroenterology 2008 Apr 30;134(4):1028-37. Epub 2008 Jan 30.

Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2008.01.070DOI Listing
April 2008

Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self.

Nat Immunol 2007 Feb 31;8(2):181-90. Epub 2006 Dec 31.

Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni1427DOI Listing
February 2007

Endocrine self and gut non-self intersect in the pancreatic lymph nodes.

Proc Natl Acad Sci U S A 2005 Dec 29;102(49):17729-33. Epub 2005 Nov 29.

Section on Immunology and Immunogenetics, Joslin Diabetes Center, and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, One Joslin Place, Boston, MA 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0509006102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1308925PMC
December 2005

Dendritic cells: inciting and inhibiting autoimmunity.

Authors:
Shannon J Turley

Curr Opin Immunol 2002 Dec;14(6):765-70

Department of Immunology and Immunogenetics, Joslin Diabetes Center, Harvard University Medical School, Boston, MA 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0952-7915(02)00399-0DOI Listing
December 2002

Projection of an immunological self shadow within the thymus by the aire protein.

Science 2002 Nov 10;298(5597):1395-401. Epub 2002 Oct 10.

Section on Immunology and Immunogenetics, Joslin Diabetes Center; Department of Medicine, Brigham and Women's Hospital; Harvard Medical School, 1 Joslin Place, Boston, MA 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1075958DOI Listing
November 2002