Satoru Miyano

Satoru Miyano

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Satoru Miyano

Satoru Miyano

Publications by authors named "Satoru Miyano"

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A Bayesian model integration for mutation calling through data partitioning.

Bioinformatics 2019 Nov;35(21):4247-4254

Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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https://academic.oup.com/bioinformatics/advance-article/doi/
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http://dx.doi.org/10.1093/bioinformatics/btz233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821361PMC
November 2019

The first case of elderly -positive B-cell acute lymphoblastic leukemia.

Leuk Lymphoma 2019 Nov 6;60(11):2821-2824. Epub 2019 May 6.

Department of Hematology/Oncology, Research Hospital, Institute of Medical Science, University of Tokyo, Tokyo, Japan.

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https://www.tandfonline.com/doi/full/10.1080/10428194.2019.1
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http://dx.doi.org/10.1080/10428194.2019.1602267DOI Listing
November 2019

Divergent lncRNA MYMLR regulates MYC by eliciting DNA looping and promoter-enhancer interaction.

EMBO J 2019 Sep 30;38(17):e98441. Epub 2019 Jul 30.

Division of Molecular Carcinogenesis, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan.

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http://dx.doi.org/10.15252/embj.201798441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717891PMC
September 2019

Development of an MSI-positive colon tumor with aberrant DNA methylation in a PPAP patient.

J Hum Genet 2019 Aug 14;64(8):729-740. Epub 2019 May 14.

Division of Clinical Genome Research, Advanced Clinical Research Center, Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1038/s10038-019-0611-7DOI Listing
August 2019

Prediction of deficiency-excess pattern in Japanese Kampo medicine: Multi-centre data collection.

Complement Ther Med 2019 Aug 5;45:228-233. Epub 2019 Jul 5.

Center for Kampo Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan; Faculty of Environmental and Information Study, Keio University, 5322 Endo, Fujisawa, Kanagawa, 252-0882, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ctim.2019.07.003DOI Listing
August 2019

Classification of patients with cold sensation by a review of systems database: A single-centre observational study.

Complement Ther Med 2019 Aug 11;45:7-13. Epub 2019 May 11.

Center for Kampo Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan; Faculty of Environmental and Information Study, Keio University, 5322 Endo, Fujisawa, Kanagawa, 252-0882, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ctim.2019.05.011DOI Listing
August 2019

Comprehensive analysis of genetic aberrations linked to tumorigenesis in regenerative nodules of liver cirrhosis.

J Gastroenterol 2019 Jul 12;54(7):628-640. Epub 2019 Feb 12.

Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

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http://dx.doi.org/10.1007/s00535-019-01555-zDOI Listing
July 2019

Robust Sample-Specific Stability Selection with Effective Error Control.

J Comput Biol 2019 Mar 14;26(3):202-217. Epub 2019 Jan 14.

4 Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1089/cmb.2018.0180DOI Listing
March 2019

Sensitivity analysis of agent-based simulation utilizing massively parallel computation and interactive data visualization.

PLoS One 2019 5;14(3):e0210678. Epub 2019 Mar 5.

Division of Health Medical Computational Science, Health Intelligence Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210678PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400389PMC
March 2019

Modification of cellular and humoral immunity by somatically reverted T cells in X-linked lymphoproliferative syndrome type 1.

J Allergy Clin Immunol 2019 01 17;143(1):421-424.e11. Epub 2018 Oct 17.

Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan; Department of Pediatrics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan; Department of Child Health and Development, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.07.044DOI Listing
January 2019

[Artificial Intelligence for Cancer Genomic Medicine: Understanding Cancer is Beyond Human Ability].

Authors:
Satoru Miyano

Brain Nerve 2019 Jan;71(1):25-32

Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, University of Tokyo.

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http://dx.doi.org/10.11477/mf.1416201213DOI Listing
January 2019

Different clonal dynamics of chronic myeloid leukaemia between bone marrow and the central nervous system.

Br J Haematol 2018 12 19;183(5):842-845. Epub 2017 Dec 19.

Department of Haematology/Oncology, Research Hospital, Institute of Medical Science, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1111/bjh.15065DOI Listing
December 2018

Azacitidine effectively reduces -mutant leukemic cell burden in secondary acute myeloid leukemia after cord blood transplantation.

Leuk Lymphoma 2018 11 12;59(11):2755-2756. Epub 2018 Apr 12.

a Division of Molecular Therapy, Advanced Clinical Research Center, the Institute of Medical Science , University of Tokyo , Tokyo , Japan.

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http://dx.doi.org/10.1080/10428194.2018.1443335DOI Listing
November 2018

ALPHLARD: a Bayesian method for analyzing HLA genes from whole genome sequence data.

BMC Genomics 2018 Nov 1;19(1):790. Epub 2018 Nov 1.

Health Intelligence Center, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

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https://bmcgenomics.biomedcentral.com/articles/10.1186/s1286
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http://dx.doi.org/10.1186/s12864-018-5169-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211482PMC
November 2018

Circulating tumor DNA dynamically predicts response and/or relapse in patients with hematological malignancies.

Int J Hematol 2018 Oct 29;108(4):402-410. Epub 2018 Jun 29.

Division of Molecular Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1007/s12185-018-2487-2DOI Listing
October 2018

Whole-exome analysis to detect congenital hemolytic anemia mimicking congenital dyserythropoietic anemia.

Int J Hematol 2018 Sep 23;108(3):306-311. Epub 2018 Jun 23.

Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, Japan.

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http://dx.doi.org/10.1007/s12185-018-2482-7DOI Listing
September 2018

Cancer evolution and heterogeneity.

Ann Gastroenterol Surg 2018 Sep 4;2(5):332-338. Epub 2018 Jul 4.

Laboratory of Sequence Analysis Human Genome Center Institute of Medical Science University of Tokyo Tokyo Japan.

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http://dx.doi.org/10.1002/ags3.12182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139712PMC
September 2018

A comprehensive characterization of -acting splicing-associated variants in human cancer.

Genome Res 2018 08 16;28(8):1111-1125. Epub 2018 Jul 16.

Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1101/gr.231951.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071634PMC
August 2018

Understanding intratumor heterogeneity by combining genome analysis and mathematical modeling.

Cancer Sci 2018 Apr 28;109(4):884-892. Epub 2018 Feb 28.

Department of Surgery, Kyushu University Beppu Hospital, Beppu, Japan.

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http://dx.doi.org/10.1111/cas.13510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891172PMC
April 2018

Phenotype-based gene analysis allowed successful diagnosis of X-linked neutropenia associated with a novel WASp mutation.

Ann Hematol 2018 Feb 27;97(2):367-369. Epub 2017 Sep 27.

Division of Molecular Therapy, Advanced Clinical Research Center, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1007/s00277-017-3134-3DOI Listing
February 2018

Adaptive NetworkProfiler for Identifying Cancer Characteristic-Specific Gene Regulatory Networks.

J Comput Biol 2018 02 20;25(2):130-145. Epub 2017 Oct 20.

4 Human Genome Center, Institute of Medical Science, University of Tokyo , Tokyo, Japan .

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http://dx.doi.org/10.1089/cmb.2017.0120DOI Listing
February 2018

Characterization of the B-cell receptor repertoires in peanut allergic subjects undergoing oral immunotherapy.

J Hum Genet 2018 Feb 30;63(2):239-248. Epub 2017 Nov 30.

Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA.

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http://dx.doi.org/10.1038/s10038-017-0364-0DOI Listing
February 2018

Distinct gene alterations with a high percentage of myeloperoxidase-positive leukemic blasts in de novo acute myeloid leukemia.

Leuk Res 2018 02 2;65:34-41. Epub 2018 Jan 2.

Department of Hematology, Atomic Bomb Disease and Hibakusha Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan; Department of Hematology, Nagasaki University Hospital, Nagasaki, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2017.12.006DOI Listing
February 2018

Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology.

Nat Commun 2018 01 30;9(1):433. Epub 2018 Jan 30.

Department of Neuropathology, Medical Research Institute and Center for Brain Integration Research, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.

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http://dx.doi.org/10.1038/s41467-018-02821-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789822PMC
January 2018

Loss of DNA Damage Response in Neuroblastoma and Utility of a PARP Inhibitor.

J Natl Cancer Inst 2017 11;109(11)

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan; Department of Pediatrics, Graduate School of Medicine, Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, Laboratory of Sequence Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Department of Pediatrics and Adolescent Medicine, School of Medicine, Juntendo University, Tokyo, Japan; Department of Pediatric Hematology/Oncology, Saitama Children's Medical Center, Saitama, Japan, Department of Pediatrics, Nagara Medical Center, Gifu, Japan; Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan; Division of Cancer Genomics, Saitama Cancer Center Research Institute, Saitama, Japan; Division of Cancer Genomics, Chiba Cancer Center, Chiba, Japan; Gunma Children's Medical Center, Gunma, Japan; Saga Medical Center, Saga, Japan.

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http://dx.doi.org/10.1093/jnci/djx062DOI Listing
November 2017

Large-scale DNA Barcode Library Generation for Biomolecule Identification in High-throughput Screens.

Sci Rep 2017 10 24;7(1):13899. Epub 2017 Oct 24.

Laboratory of Functional Genomics, Department of Computational Biology and Medical Science, School of Frontier Sciences, University of Tokyo, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1038/s41598-017-12825-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654825PMC
October 2017

Identification of a p53 target, CD137L, that mediates growth suppression and immune response of osteosarcoma cells.

Sci Rep 2017 09 6;7(1):10739. Epub 2017 Sep 6.

Laboratory of Clinical Genome Sequencing, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/s41598-017-11208-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587585PMC
September 2017

Identification of a p53-repressed gene module in breast cancer cells.

Oncotarget 2017 Aug 26;8(34):55821-55836. Epub 2017 Jul 26.

Laboratory of Clinical Genome Sequencing, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.18632/oncotarget.19608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593526PMC
August 2017

The Transcriptional Landscape of p53 Signalling Pathway.

EBioMedicine 2017 Jun 18;20:109-119. Epub 2017 May 18.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan; Laboratory of Clinical Genome Sequence, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478243PMC
June 2017

Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer.

Oncol Rep 2017 May 29;37(5):2603-2610. Epub 2017 Mar 29.

Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.3892/or.2017.5536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428285PMC
May 2017

phyC: Clustering cancer evolutionary trees.

PLoS Comput Biol 2017 05 1;13(5):e1005509. Epub 2017 May 1.

Division of Systems Biology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

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http://dx.doi.org/10.1371/journal.pcbi.1005509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432190PMC
May 2017

Sequence-specific bias correction for RNA-seq data using recurrent neural networks.

BMC Genomics 2017 01 25;18(Suppl 1):1044. Epub 2017 Jan 25.

The Institute of Medical Science, The University of Tokyo, Shirokanedai 4-6-1, Minato-ku, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1186/s12864-016-3262-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310274PMC
January 2017