Publications by authors named "Satoru Miyano"

100Publications

Metagenome Data on Intestinal Phage-Bacteria Associations Aids the Development of Phage Therapy against Pathobionts.

Cell Host Microbe 2020 09 10;28(3):380-389.e9. Epub 2020 Jul 10.

Department of Immunology and Genomics, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan; Division of Metagenome Medicine, Human Genome Center, the Institute of Medical Sciences, the University of Tokyo, Tokyo 108-8639, Japan; Division of Innate Immune Regulation, International Research and Development Center for Mucosal Vaccines, the Institute of Medical Sciences, the University of Tokyo, Tokyo 108-8639, Japan; Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Tokyo 113-8657, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2020.06.005DOI Listing
September 2020

Nanopore basecalling from a perspective of instance segmentation.

BMC Bioinformatics 2020 Apr 23;21(Suppl 3):136. Epub 2020 Apr 23.

The Institute of Medical Science, The University of Tokyo, Shirokanedai 4-6-1, Minato-ku, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1186/s12859-020-3459-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178565PMC
April 2020

A unified simulation model for understanding the diversity of cancer evolution.

PeerJ 2020 8;8:e8842. Epub 2020 Apr 8.

Laboratory of DNA Information Analysis, Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.7717/peerj.8842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150545PMC
April 2020

Discrimination of prediction models between cold-heat and deficiency-excess patterns.

Complement Ther Med 2020 Mar 20;49:102353. Epub 2020 Feb 20.

Center for Kampo Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ctim.2020.102353DOI Listing
March 2020

Variant analysis of prostate cancer in Japanese patients and a new attempt to predict related biological pathways.

Oncol Rep 2020 Mar 27;43(3):943-952. Epub 2020 Jan 27.

Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Kanagawa 241‑8515, Japan.

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http://dx.doi.org/10.3892/or.2020.7481DOI Listing
March 2020

Virtual Grid Engine: a simulated grid engine environment for large-scale supercomputers.

BMC Bioinformatics 2019 Dec 2;20(Suppl 16):591. Epub 2019 Dec 2.

The Institute of Medical Science, The University of Tokyo, Shirokanedai 4-6-1, Minato-ku, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1186/s12859-019-3085-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886159PMC
December 2019

Divergent lncRNA MYMLR regulates MYC by eliciting DNA looping and promoter-enhancer interaction.

EMBO J 2019 09 30;38(17):e98441. Epub 2019 Jul 30.

Division of Molecular Carcinogenesis, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan.

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http://dx.doi.org/10.15252/embj.201798441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717891PMC
September 2019

Classification of patients with cold sensation by a review of systems database: A single-centre observational study.

Complement Ther Med 2019 Aug 11;45:7-13. Epub 2019 May 11.

Center for Kampo Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan; Faculty of Environmental and Information Study, Keio University, 5322 Endo, Fujisawa, Kanagawa, 252-0882, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ctim.2019.05.011DOI Listing
August 2019

Prediction of deficiency-excess pattern in Japanese Kampo medicine: Multi-centre data collection.

Complement Ther Med 2019 Aug 5;45:228-233. Epub 2019 Jul 5.

Center for Kampo Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan; Faculty of Environmental and Information Study, Keio University, 5322 Endo, Fujisawa, Kanagawa, 252-0882, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ctim.2019.07.003DOI Listing
August 2019

Development of an MSI-positive colon tumor with aberrant DNA methylation in a PPAP patient.

J Hum Genet 2019 Aug 14;64(8):729-740. Epub 2019 May 14.

Division of Clinical Genome Research, Advanced Clinical Research Center, Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1038/s10038-019-0611-7DOI Listing
August 2019

The first case of elderly -positive B-cell acute lymphoblastic leukemia.

Leuk Lymphoma 2019 11 6;60(11):2821-2824. Epub 2019 May 6.

Department of Hematology/Oncology, Research Hospital, Institute of Medical Science, University of Tokyo, Tokyo, Japan.

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https://www.tandfonline.com/doi/full/10.1080/10428194.2019.1
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http://dx.doi.org/10.1080/10428194.2019.1602267DOI Listing
November 2019

A Bayesian model integration for mutation calling through data partitioning.

Bioinformatics 2019 11;35(21):4247-4254

Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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https://academic.oup.com/bioinformatics/advance-article/doi/
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http://dx.doi.org/10.1093/bioinformatics/btz233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821361PMC
November 2019

Sensitivity analysis of agent-based simulation utilizing massively parallel computation and interactive data visualization.

PLoS One 2019 5;14(3):e0210678. Epub 2019 Mar 5.

Division of Health Medical Computational Science, Health Intelligence Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210678PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400389PMC
November 2019

Comprehensive analysis of genetic aberrations linked to tumorigenesis in regenerative nodules of liver cirrhosis.

J Gastroenterol 2019 Jul 12;54(7):628-640. Epub 2019 Feb 12.

Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

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http://dx.doi.org/10.1007/s00535-019-01555-zDOI Listing
July 2019

Robust Sample-Specific Stability Selection with Effective Error Control.

J Comput Biol 2019 03 14;26(3):202-217. Epub 2019 Jan 14.

4 Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1089/cmb.2018.0180DOI Listing
March 2019

[Artificial Intelligence for Cancer Genomic Medicine: Understanding Cancer is Beyond Human Ability].

Authors:
Satoru Miyano

Brain Nerve 2019 Jan;71(1):25-32

Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, University of Tokyo.

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http://dx.doi.org/10.11477/mf.1416201213DOI Listing
January 2019

ALPHLARD: a Bayesian method for analyzing HLA genes from whole genome sequence data.

BMC Genomics 2018 Nov 1;19(1):790. Epub 2018 Nov 1.

Health Intelligence Center, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

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https://bmcgenomics.biomedcentral.com/articles/10.1186/s1286
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http://dx.doi.org/10.1186/s12864-018-5169-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211482PMC
November 2018

Modification of cellular and humoral immunity by somatically reverted T cells in X-linked lymphoproliferative syndrome type 1.

J Allergy Clin Immunol 2019 01 17;143(1):421-424.e11. Epub 2018 Oct 17.

Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan; Department of Pediatrics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan; Department of Child Health and Development, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.07.044DOI Listing
January 2019

Cancer evolution and heterogeneity.

Ann Gastroenterol Surg 2018 Sep 4;2(5):332-338. Epub 2018 Jul 4.

Laboratory of Sequence Analysis Human Genome Center Institute of Medical Science University of Tokyo Tokyo Japan.

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http://dx.doi.org/10.1002/ags3.12182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139712PMC
September 2018

A comprehensive characterization of -acting splicing-associated variants in human cancer.

Genome Res 2018 08 16;28(8):1111-1125. Epub 2018 Jul 16.

Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1101/gr.231951.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071634PMC
August 2018

Circulating tumor DNA dynamically predicts response and/or relapse in patients with hematological malignancies.

Int J Hematol 2018 Oct 29;108(4):402-410. Epub 2018 Jun 29.

Division of Molecular Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1007/s12185-018-2487-2DOI Listing
October 2018

Whole-exome analysis to detect congenital hemolytic anemia mimicking congenital dyserythropoietic anemia.

Int J Hematol 2018 Sep 23;108(3):306-311. Epub 2018 Jun 23.

Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, Japan.

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http://dx.doi.org/10.1007/s12185-018-2482-7DOI Listing
September 2018

Azacitidine effectively reduces -mutant leukemic cell burden in secondary acute myeloid leukemia after cord blood transplantation.

Leuk Lymphoma 2018 11 12;59(11):2755-2756. Epub 2018 Apr 12.

a Division of Molecular Therapy, Advanced Clinical Research Center, the Institute of Medical Science , University of Tokyo , Tokyo , Japan.

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http://dx.doi.org/10.1080/10428194.2018.1443335DOI Listing
November 2018

Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology.

Nat Commun 2018 01 30;9(1):433. Epub 2018 Jan 30.

Department of Neuropathology, Medical Research Institute and Center for Brain Integration Research, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.

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http://dx.doi.org/10.1038/s41467-018-02821-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789822PMC
January 2018

Understanding intratumor heterogeneity by combining genome analysis and mathematical modeling.

Cancer Sci 2018 Apr 28;109(4):884-892. Epub 2018 Feb 28.

Department of Surgery, Kyushu University Beppu Hospital, Beppu, Japan.

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http://dx.doi.org/10.1111/cas.13510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891172PMC
April 2018

Distinct gene alterations with a high percentage of myeloperoxidase-positive leukemic blasts in de novo acute myeloid leukemia.

Leuk Res 2018 02 2;65:34-41. Epub 2018 Jan 2.

Department of Hematology, Atomic Bomb Disease and Hibakusha Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan; Department of Hematology, Nagasaki University Hospital, Nagasaki, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2017.12.006DOI Listing
February 2018

Different clonal dynamics of chronic myeloid leukaemia between bone marrow and the central nervous system.

Br J Haematol 2018 12 19;183(5):842-845. Epub 2017 Dec 19.

Department of Haematology/Oncology, Research Hospital, Institute of Medical Science, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1111/bjh.15065DOI Listing
December 2018

Characterization of the B-cell receptor repertoires in peanut allergic subjects undergoing oral immunotherapy.

J Hum Genet 2018 Feb 30;63(2):239-248. Epub 2017 Nov 30.

Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA.

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http://dx.doi.org/10.1038/s10038-017-0364-0DOI Listing
February 2018

Large-scale DNA Barcode Library Generation for Biomolecule Identification in High-throughput Screens.

Sci Rep 2017 10 24;7(1):13899. Epub 2017 Oct 24.

Laboratory of Functional Genomics, Department of Computational Biology and Medical Science, School of Frontier Sciences, University of Tokyo, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1038/s41598-017-12825-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654825PMC
October 2017

Loss of DNA Damage Response in Neuroblastoma and Utility of a PARP Inhibitor.

J Natl Cancer Inst 2017 11;109(11)

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan; Department of Pediatrics, Graduate School of Medicine, Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, Laboratory of Sequence Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Department of Pediatrics and Adolescent Medicine, School of Medicine, Juntendo University, Tokyo, Japan; Department of Pediatric Hematology/Oncology, Saitama Children's Medical Center, Saitama, Japan, Department of Pediatrics, Nagara Medical Center, Gifu, Japan; Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan; Division of Cancer Genomics, Saitama Cancer Center Research Institute, Saitama, Japan; Division of Cancer Genomics, Chiba Cancer Center, Chiba, Japan; Gunma Children's Medical Center, Gunma, Japan; Saga Medical Center, Saga, Japan.

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http://dx.doi.org/10.1093/jnci/djx062DOI Listing
November 2017

Adaptive NetworkProfiler for Identifying Cancer Characteristic-Specific Gene Regulatory Networks.

J Comput Biol 2018 02 20;25(2):130-145. Epub 2017 Oct 20.

4 Human Genome Center, Institute of Medical Science, University of Tokyo , Tokyo, Japan .

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http://dx.doi.org/10.1089/cmb.2017.0120DOI Listing
February 2018

Phenotype-based gene analysis allowed successful diagnosis of X-linked neutropenia associated with a novel WASp mutation.

Ann Hematol 2018 Feb 27;97(2):367-369. Epub 2017 Sep 27.

Division of Molecular Therapy, Advanced Clinical Research Center, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1007/s00277-017-3134-3DOI Listing
February 2018

Identification of a p53-repressed gene module in breast cancer cells.

Oncotarget 2017 Aug 26;8(34):55821-55836. Epub 2017 Jul 26.

Laboratory of Clinical Genome Sequencing, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.18632/oncotarget.19608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593526PMC
August 2017

Identification of a p53 target, CD137L, that mediates growth suppression and immune response of osteosarcoma cells.

Sci Rep 2017 09 6;7(1):10739. Epub 2017 Sep 6.

Laboratory of Clinical Genome Sequencing, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/s41598-017-11208-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587585PMC
September 2017