Sarah Howlett

Sarah Howlett

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Sarah Howlett

Sarah Howlett

Publications by authors named "Sarah Howlett"

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A long-lived IL-2 mutein that selectively activates and expands regulatory T cells as a therapy for autoimmune disease.

J Autoimmun 2018 12 13;95:1-14. Epub 2018 Nov 13.

JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK; JDRF/Wellcome Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, CB2 OXY, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08968411183042
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http://dx.doi.org/10.1016/j.jaut.2018.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284106PMC
December 2018

Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice.

J Immunol 2015 Nov 5;195(10):4841-52. Epub 2015 Oct 5.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom;

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http://dx.doi.org/10.4049/jimmunol.1402654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635565PMC
November 2015

Sustained in vivo signaling by long-lived IL-2 induces prolonged increases of regulatory T cells.

J Autoimmun 2015 Jan 30;56:66-80. Epub 2014 Oct 30.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge CB2 OXY, United Kingdom; Former Roche Site of Pharmaceutical Research and Early Development, Discovery Inflammation, Nutley, NJ 07110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2014.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298360PMC
January 2015

Evidence that Cd101 is an autoimmune diabetes gene in nonobese diabetic mice.

J Immunol 2011 Jul 25;187(1):325-36. Epub 2011 May 25.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.1003523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128927PMC
July 2011

Munch and Move: evaluation of a preschool healthy eating and movement skill program.

Int J Behav Nutr Phys Act 2010 Nov 3;7:80. Epub 2010 Nov 3.

Prevention Research Collaboration, School of Public Health, University of Sydney, NSW Australia.

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http://dx.doi.org/10.1186/1479-5868-7-80DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988057PMC
November 2010

Fundamental movement skills among Australian preschool children.

J Sci Med Sport 2010 Sep 22;13(5):503-8. Epub 2009 Oct 22.

Physical Activity, Nutrition and Obesity Research Group, University of Sydney, Camperdown, NSW, Australia.

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http://dx.doi.org/10.1016/j.jsams.2009.05.010DOI Listing
September 2010

Opening up Australian preschoolers' lunchboxes.

Aust N Z J Public Health 2010 Jun;34(3):288-92

Physical Activity Nutrition and Obesity Research Group, School of Public Health, University of Sydney, New South Wales.

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http://dx.doi.org/10.1111/j.1753-6405.2010.00528.xDOI Listing
June 2010

Nonobese diabetic congenic strain analysis of autoimmune diabetes reveals genetic complexity of the Idd18 locus and identifies Vav3 as a candidate gene.

J Immunol 2010 May 2;184(9):5075-84. Epub 2010 Apr 2.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge.

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http://dx.doi.org/10.4049/jimmunol.0903734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886967PMC
May 2010

Adolescent-parent interactions and communication preferences regarding body weight and weight management: a qualitative study.

Int J Behav Nutr Phys Act 2010 Feb 16;7:16. Epub 2010 Feb 16.

Physical Activity Nutrition and Obesity Research Group, Sydney University, Sydney, Australia.

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http://dx.doi.org/10.1186/1479-5868-7-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831813PMC
February 2010

Adolescent-parent interactions and attitudes around screen time and sugary drink consumption: a qualitative study.

Int J Behav Nutr Phys Act 2009 Sep 9;6:61. Epub 2009 Sep 9.

Physical Activity Nutrition Obesity Research Group, University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1186/1479-5868-6-61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747835PMC
September 2009

NKG2D-RAE-1 receptor-ligand variation does not account for the NK cell defect in nonobese diabetic mice.

J Immunol 2008 Nov;181(10):7073-80

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2590656PMC
http://dx.doi.org/10.4049/jimmunol.181.10.7073DOI Listing
November 2008

Commonality in the genetic control of Type 1 diabetes in humans and NOD mice: variants of genes in the IL-2 pathway are associated with autoimmune diabetes in both species.

Biochem Soc Trans 2008 Jun;36(Pt 3):312-5

Juvenile Diabetes Research Foundation/Wellcome Trust (JDRF/WT) Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, UK.

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http://biochemsoctrans.org/lookup/doi/10.1042/BST0360312
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http://dx.doi.org/10.1042/BST0360312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2590655PMC
June 2008

Derivation of pluripotent epiblast stem cells from mammalian embryos.

Nature 2007 Jul 27;448(7150):191-5. Epub 2007 Jun 27.

Department of Surgery and Cambridge Institute for Medical Research, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1038/nature05950DOI Listing
July 2007

Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity.

Nat Genet 2007 Mar 4;39(3):329-37. Epub 2007 Feb 4.

Julia McFarlane Diabetes Research Centre (JMDRC) and Department of Microbiology and Infectious Diseases, Institute of Inflammation, Infection and Immunity, Faculty of Medicine, The University of Calgary, Calgary, Alberta T2N 4N1, Canada.

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http://dx.doi.org/10.1038/ng1958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886969PMC
March 2007

Type 1 diabetes genes and pathways shared by humans and NOD mice.

J Autoimmun 2005 28;25 Suppl:29-33. Epub 2005 Oct 28.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, University of Cambridge, Cambridge Institute for Medical Research, Cambridge CB2 2XY, UK.

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http://dx.doi.org/10.1016/j.jaut.2005.09.009DOI Listing
June 2006

Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse.

Novartis Found Symp 2005 ;267:57-65; discussion 65-75

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes & Inflammation Laboratory, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 2XY, UK.

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November 2005

Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse.

J Immunol 2004 Jul;173(1):164-73

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 2XY, UK.

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http://dx.doi.org/10.4049/jimmunol.173.1.164DOI Listing
July 2004

The effect of inhibiting DNA replication in the one-cell mouse embryo.

Authors:
Sarah K Howlett

Roux Arch Dev Biol 1986 Oct;195(8):499-505

Department of Anatomy, Downing Street, Cambridge, Great Britain.

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http://dx.doi.org/10.1007/BF00375890DOI Listing
October 1986