Sander B Nabuurs

Sander B Nabuurs

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Sander B Nabuurs

Sander B Nabuurs

Publications by authors named "Sander B Nabuurs"

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40Publications

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Discovery of small molecule CD40-TRAF6 inhibitors.

J Chem Inf Model 2015 Feb 27;55(2):294-307. Epub 2015 Jan 27.

Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University , 6200 MD Maastricht, The Netherlands.

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http://dx.doi.org/10.1021/ci500631eDOI Listing
February 2015

A 3-base pair deletion, c.9711_9713del, in DMD results in intellectual disability without muscular dystrophy.

Eur J Hum Genet 2014 Apr 31;22(4):480-5. Epub 2013 Jul 31.

1] Department of Human Genetics, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands [2] Institute of Genetic and Metabolic Disease, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands [3] Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/ejhg.2013.169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953899PMC
April 2014

Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.

Antiviral Res 2014 Mar 4;103:17-24. Epub 2014 Jan 4.

Department of Medical Microbiology, Nijmegen Centre for Molecular Life Sciences & Nijmegen Institute for Infection, Inflammation and Immunity, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2013.12.012DOI Listing
March 2014

A complex V ATP5A1 defect causes fatal neonatal mitochondrial encephalopathy.

Brain 2013 May 18;136(Pt 5):1544-54. Epub 2013 Apr 18.

Department of Paediatrics, Nijmegen Centre for Mitochondrial Disorders, Laboratory for Genetic, Endocrine, and Metabolic Disorders, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/brain/awt086DOI Listing
May 2013

Evolution and diversification of the organellar release factor family.

Mol Biol Evol 2012 Nov 11;29(11):3497-512. Epub 2012 Jun 11.

Centre for Molecular and Biomolecular Informatics, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/molbev/mss157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472500PMC
November 2012

CING: an integrated residue-based structure validation program suite.

J Biomol NMR 2012 Nov 18;54(3):267-83. Epub 2012 Sep 18.

CMBI, Radboud University Medical Centre, Geert Grooteplein 26-28, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s10858-012-9669-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483101PMC
November 2012

In silico identification of potential cholestasis-inducing agents via modeling of Na(+)-dependent taurocholate cotransporting polypeptide substrate specificity.

Toxicol Sci 2012 Sep 28;129(1):35-48. Epub 2012 May 28.

Department of Pharmacology and Toxicology, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

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https://academic.oup.com/toxsci/article-lookup/doi/10.1093/t
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http://dx.doi.org/10.1093/toxsci/kfs188DOI Listing
September 2012

Enzyme-specific activation versus leaving group ability.

Chembiochem 2012 Aug 23;13(12):1785-90. Epub 2012 Jul 23.

Institute for Molecules and Materials, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/cbic.201200227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569868PMC
August 2012

Papain-specific activating esters in aqueous dipeptide synthesis.

Chembiochem 2012 Jun 21;13(9):1319-26. Epub 2012 May 21.

Institute for Molecules and Materials, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands.

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http://doi.wiley.com/10.1002/cbic.201200017
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http://dx.doi.org/10.1002/cbic.201200017DOI Listing
June 2012

Flexible protein-ligand docking using the Fleksy protocol.

J Comput Chem 2012 May 28;33(12):1215-7. Epub 2012 Feb 28.

Department of Molecular Design and Informatics, MSD, Oss, The Netherlands.

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http://dx.doi.org/10.1002/jcc.22948DOI Listing
May 2012

Structure based hypothesis of a mitochondrial ribosome rescue mechanism.

Biol Direct 2012 May 8;7:14. Epub 2012 May 8.

Centre for Molecular and Biomolecular Informatics, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, P,O, Box 9101, 6400, HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/1745-6150-7-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418547PMC
May 2012

Gaussian interaction profile kernels for predicting drug-target interaction.

Bioinformatics 2011 Nov 4;27(21):3036-43. Epub 2011 Sep 4.

Department of Computer Science, Radboud University Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/bioinformatics/btr500DOI Listing
November 2011

Papain-catalyzed peptide bond formation: enzyme-specific activation with guanidinophenyl esters.

Chembiochem 2011 Sep 8;12(14):2201-7. Epub 2011 Aug 8.

Institute for Molecules and Materials, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/cbic.201100267DOI Listing
September 2011

Snooker: a structure-based pharmacophore generation tool applied to class A GPCRs.

J Chem Inf Model 2011 Sep 6;51(9):2277-92. Epub 2011 Sep 6.

Computational Drug Discovery Group, CMBI, Radboud University Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1021/ci200088dDOI Listing
September 2011

NDUFB7 and NDUFA8 are located at the intermembrane surface of complex I.

FEBS Lett 2011 Mar 22;585(5):737-43. Epub 2011 Feb 22.

Centre for Molecular and Biomolecular Informatics, Radboud University Nijmegen Medical Centre, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.febslet.2011.01.046DOI Listing
March 2011

PRPS1 mutations: four distinct syndromes and potential treatment.

Am J Hum Genet 2010 Apr;86(4):506-18

Department of Human Genetics, Nijmegen Centre for Molecular Life Sciences and Institute of Genetic and Metabolic Diseases, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ajhg.2010.02.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850427PMC
April 2010

Two divergent leptin paralogues in zebrafish (Danio rerio) that originate early in teleostean evolution.

J Endocrinol 2009 Jun 17;201(3):329-39. Epub 2009 Mar 17.

Department of Animal Physiology, Faculty of Science, Radboud University Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1677/JOE-09-0034DOI Listing
June 2009

Features of a twin-arginine signal peptide required for recognition by a Tat proofreading chaperone.

FEBS Lett 2008 Dec 12;582(29):3979-84. Epub 2008 Nov 12.

Division of Molecular and Environmental Microbiology, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, United Kingdom.

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http://dx.doi.org/10.1016/j.febslet.2008.10.049DOI Listing
December 2008

Stress and innate immunity in carp: corticosteroid receptors and pro-inflammatory cytokines.

Mol Immunol 2008 Nov 19;46(1):70-9. Epub 2008 Sep 19.

Cell Biology and Immunology Group, Wageningen University, Marijkeweg 40, 6709 PG Wageningen, The Netherlands.

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http://dx.doi.org/10.1016/j.molimm.2008.07.022DOI Listing
November 2008

Basal laminar drusen caused by compound heterozygous variants in the CFH gene.

Am J Hum Genet 2008 Feb;82(2):516-23

Department of Ophthalmology, Radboud University Nijmegen Medical Centre, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ajhg.2007.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427272PMC
February 2008

A flexible approach to induced fit docking.

J Med Chem 2007 Dec 22;50(26):6507-18. Epub 2007 Nov 22.

Center for Molecular and Biomolecular Informatics, Radboud University, Nijmegen, The Netherlands.

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http://pubs.acs.org/doi/abs/10.1021/jm070593p
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http://dx.doi.org/10.1021/jm070593pDOI Listing
December 2007

Increased leptin expression in common Carp (Cyprinus carpio) after food intake but not after fasting or feeding to satiation.

Endocrinology 2006 Dec 24;147(12):5786-97. Epub 2006 Aug 24.

Department of Animal Physiology, Faculty of Science, Radboud University Nijmegen, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands.

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http://dx.doi.org/10.1210/en.2006-0824DOI Listing
December 2006

Negative constraints underlie the ErbB specificity of epidermal growth factor-like ligands.

J Biol Chem 2006 Dec 10;281(52):40033-40. Epub 2006 Oct 10.

Department of Cell Biology and Centre for Molecular and Biomolecular Informatics, Radboud University Nijmegen, Faculty of Science, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M603168200DOI Listing
December 2006

The presence of multiple and differentially regulated interleukin-12p40 genes in bony fishes signifies an expansion of the vertebrate heterodimeric cytokine family.

Mol Immunol 2006 Apr 7;43(10):1519-33. Epub 2006 Feb 7.

Department of Cell Biology and Immunology, Wageningen University, Marijkeweg 40, 6709 PG Wageningen, The Netherlands.

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http://dx.doi.org/10.1016/j.molimm.2005.10.010DOI Listing
April 2006

Traditional biomolecular structure determination by NMR spectroscopy allows for major errors.

PLoS Comput Biol 2006 Feb 3;2(2):e9. Epub 2006 Feb 3.

Center for Molecular and Biomolecular Informatics, Nijmegen Center for Molecular Life Sciences, Radboud University, Nijmegen, Netherlands.

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http://dx.doi.org/10.1371/journal.pcbi.0020009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1359070PMC
February 2006

Definition of a new information-based per-residue quality parameter.

J Biomol NMR 2005 Oct;33(2):123-34

Center for Molecular and Biomolecular Informatics, NCMLS, Radboud University Nijmegen, Toernooiveld 1, 6525, ED, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s10858-005-2826-5DOI Listing
October 2005

Making optimal use of empirical energy functions: force-field parameterization in crystal space.

Proteins 2004 Dec;57(4):678-83

Center for Molecular and Biomolecular Informatics, University of Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/prot.20251DOI Listing
December 2004

DRESS: a database of REfined solution NMR structures.

Proteins 2004 May;55(3):483-6

Center for Molecular and Biomolecular Informatics, University of Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/prot.20118DOI Listing
May 2004

A closed binding pocket and global destabilization modify the binding properties of an alternatively spliced form of the second PDZ domain of PTP-BL.

Structure 2004 Jan;12(1):11-20

Department of Biophysical Chemistry, NSRIM Center, University of Nijmegen, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.str.2003.11.023DOI Listing
January 2004

Quantitative evaluation of experimental NMR restraints.

J Am Chem Soc 2003 Oct;125(39):12026-34

Center for Molecular and Biomolecular Informatics, University of Nijmegen, The Netherlands.

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http://dx.doi.org/10.1021/ja035440fDOI Listing
October 2003

Homology modeling.

Methods Biochem Anal 2003 ;44:509-23

Center for Molecular and Biomolecular Informatics, University of Nijmegen, Nijmegen, The Netherlands.

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April 2003

The precision of NMR structure ensembles revisited.

J Biomol NMR 2003 Mar;25(3):225-34

Centre for Molecular and Biomolecular Informatics, University of Nijmegen, The Netherlands.

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http://dx.doi.org/10.1023/a:1022819716110DOI Listing
March 2003