Robert Powers

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Functional Evolution of Proteins.

Proteins 2019 Feb 3. Epub 2019 Feb 3.

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska.

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http://dx.doi.org/10.1002/prot.25670DOI Listing
February 2019

O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3.

Immunity 2019 Feb 12. Epub 2019 Feb 12.

Department of Microbial Infection and Immunity, Infectious Disease Institute, The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613193003
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http://dx.doi.org/10.1016/j.immuni.2019.01.007DOI Listing
February 2019

In Reply.

Obstet Gynecol 2019 Jan;133(1):190-191

Magee-Womens Research Institute, Pittsburgh, Pennsylvania Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania Magee-Womens Research Institute, Pittsburgh, Pennsylvania Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1097/AOG.0000000000003046DOI Listing
January 2019

Combining Mass Spectrometry and NMR Improves Metabolite Detection and Annotation.

J Proteome Res 2018 Nov 12;17(11):4017-4022. Epub 2018 Oct 12.

Department of Chemistry , University of Nebraska , Lincoln , Nebraska 68588-0304 , United States.

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http://pubs.acs.org/doi/10.1021/acs.jproteome.8b00567
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http://dx.doi.org/10.1021/acs.jproteome.8b00567DOI Listing
November 2018

Insights into gemcitabine resistance and the potential for therapeutic monitoring.

Metabolomics 2018 Nov 27;14(12):156. Epub 2018 Nov 27.

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE, 68588, USA.

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http://link.springer.com/10.1007/s11306-018-1452-7
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http://dx.doi.org/10.1007/s11306-018-1452-7DOI Listing
November 2018

Maternal Outcomes Associated With Lower Range Stage 1 Hypertension.

Obstet Gynecol 2018 Oct;132(4):843-849

Magee-Womens Research Institute, and the Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1097/AOG.0000000000002870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331002PMC
October 2018

Methanol Detected in a Subdural Hematoma as an Embalming Artifact.

J Forensic Sci 2018 Oct 2. Epub 2018 Oct 2.

Hamilton County Coroner's Office, 3159 Eden Ave., Cincinnati, OH, 45219.

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http://dx.doi.org/10.1111/1556-4029.13913DOI Listing
October 2018

Comparing normalization methods and the impact of noise.

Metabolomics 2018 Aug 10;14(8):108. Epub 2018 Aug 10.

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE, 68588-0304, USA.

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http://dx.doi.org/10.1007/s11306-018-1400-6DOI Listing
August 2018

Expanding the Coverage of the Metabolome with Nitrogen-Based NMR.

Anal Chem 2018 04 15;90(7):4521-4528. Epub 2018 Mar 15.

Center for Staphylococcal Research, Department of Pathology and Microbiology , University of Nebraska Medical Center , Omaha , Nebraska 68198-5900 , United States.

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http://dx.doi.org/10.1021/acs.analchem.7b04922DOI Listing
April 2018

N CEST data and traditional model-free analysis capture fast internal dynamics of DJ-1.

Anal Biochem 2018 02 21;542:24-28. Epub 2017 Nov 21.

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0304, USA; Nebraska Center for Integrated Biomolecular Communication, University of Nebraska-Lincoln, Lincoln, NE 68588-0304, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2017.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817017PMC
February 2018

Metabolic Mitigation of Staphylococcus aureus Vancomycin Intermediate-Level Susceptibility.

Antimicrob Agents Chemother 2018 01 21;62(1). Epub 2017 Dec 21.

School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, USA

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http://dx.doi.org/10.1128/AAC.01608-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740343PMC
January 2018

The ER morphology-regulating lunapark protein induces the formation of stacked bilayer discs.

Life Sci Alliance 2018 Jan 19;1(1):e201700014. Epub 2018 Jan 19.

Howard Hughes Medical Institute and Department of Cell Biology, Harvard Medical School, Boston, MA, USA.

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http://www.life-science-alliance.org/lookup/doi/10.26508/lsa
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http://dx.doi.org/10.26508/lsa.201700014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238531PMC
January 2018

Mitochondrial dysfunction in glial cells: Implications for neuronal homeostasis and survival.

Toxicology 2017 11 26;391:109-115. Epub 2017 Jun 26.

School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583, United States; Redox Biology Center, University of Nebraska-Lincoln, Lincoln, NE 68588, United States. Electronic address:

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http://dx.doi.org/10.1016/j.tox.2017.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681369PMC
November 2017

GPR55 receptor antagonist decreases glycolytic activity in PANC-1 pancreatic cancer cell line and tumor xenografts.

Int J Cancer 2017 11 7;141(10):2131-2142. Epub 2017 Aug 7.

Laboratory of Clinical Investigation, Intramural Research Program of the National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224.

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http://dx.doi.org/10.1002/ijc.30904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028007PMC
November 2017

Glucose Limitation Alters Glutamine Metabolism in MUC1-Overexpressing Pancreatic Cancer Cells.

J Proteome Res 2017 10 30;16(10):3536-3546. Epub 2017 Aug 30.

Department of Chemistry, and ‡Nebraska Center for Integrated Biomolecular Communication, University of Nebraska-Lincoln , Lincoln, Nebraska 68588, United States.

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http://dx.doi.org/10.1021/acs.jproteome.7b00246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634392PMC
October 2017

Nanoformulated copper/zinc superoxide dismutase exerts differential effects on glucose vs lipid homeostasis depending on the diet composition possibly via altered AMPK signaling.

Transl Res 2017 10 15;188:10-26. Epub 2017 Aug 15.

Department of Internal Medicine/Division of Diabetes, Endocrinology, and Metabolism, University of Nebraska Medical Center, Omaha, Neb; VA Nebraska-Western Iowa Health Care System, Omaha, Neb. Electronic address:

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http://dx.doi.org/10.1016/j.trsl.2017.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819896PMC
October 2017

Low Soluble Syndecan-1 Precedes Preeclampsia.

PLoS One 2016 14;11(6):e0157608. Epub 2016 Jun 14.

Department of Obstetrics, Gynecology & Reproductive Sciences, Division of Maternal Fetal Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157608PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907460PMC
July 2017

Metabolic Dysfunction in Parkinson's Disease: Bioenergetics, Redox Homeostasis and Central Carbon Metabolism.

Brain Res Bull 2017 Jul 21;133:12-30. Epub 2017 Mar 21.

School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68516, United States; Redox Biology Center, University of Nebraska-Lincoln, Lincoln, NE 68503, United States. Electronic address:

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http://dx.doi.org/10.1016/j.brainresbull.2017.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555796PMC
July 2017

New frontiers in metabolomics: from measurement to insight.

F1000Res 2017 19;6:1148. Epub 2017 Jul 19.

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE, USA.

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http://dx.doi.org/10.12688/f1000research.11495.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521158PMC
July 2017

Beyond the paradigm: Combining mass spectrometry and nuclear magnetic resonance for metabolomics.

Prog Nucl Magn Reson Spectrosc 2017 05 11;100:1-16. Epub 2017 Jan 11.

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0304, United States. Electronic address:

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http://dx.doi.org/10.1016/j.pnmrs.2017.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448308PMC
May 2017

Keratin 17 is overexpressed and predicts poor survival in estrogen receptor-negative/human epidermal growth factor receptor-2-negative breast cancer.

Hum Pathol 2017 04 2;62:23-32. Epub 2016 Nov 2.

Department of Pathology, Stony Brook University School of Medicine, New York, NY 11794-8691, USA. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2016.10.006DOI Listing
April 2017

Assessment of Metabolic Changes in Mycobacterium smegmatis Wild-Type and alr Mutant Strains: Evidence of a New Pathway of d-Alanine Biosynthesis.

J Proteome Res 2017 03 14;16(3):1270-1279. Epub 2017 Feb 14.

Department of Chemistry, University of Nebraska-Lincoln , Lincoln, Nebraska 68588-0304, United States.

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http://dx.doi.org/10.1021/acs.jproteome.6b00871DOI Listing
March 2017

Reconstitution of the tubular endoplasmic reticulum network with purified components.

Nature 2017 03 22;543(7644):257-260. Epub 2017 Feb 22.

Howard Hughes Medical Institute, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nature21387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853125PMC
March 2017

A Partial Calcium-Free Linker Confers Flexibility to Inner-Ear Protocadherin-15.

Structure 2017 03 23;25(3):482-495. Epub 2017 Feb 23.

Department of Chemistry and Biochemistry, The Ohio State University, 484 West 12(th) Avenue, Columbus, OH 43210, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2017.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363953PMC
March 2017

The future of NMR-based metabolomics.

Curr Opin Biotechnol 2017 02 28;43:34-40. Epub 2016 Aug 28.

Department of Biological Sciences, University of Alberta, Edmonton, AB, Canada T6G 2E8; Department of Computing Science, University of Alberta, Edmonton, AB, Canada T6G 2E8.

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http://dx.doi.org/10.1016/j.copbio.2016.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305426PMC
February 2017

Extracellular matrix regenerative graft attenuates the negative impact of polypropylene prolapse mesh on vagina in rhesus macaque.

Am J Obstet Gynecol 2017 Feb 8;216(2):153.e1-153.e9. Epub 2016 Sep 8.

Magee Women Research Institute, University of Pittsburgh, Pittsburgh, PA; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA; Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of Pittsburgh, Pittsburgh, PA. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2016.09.073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290183PMC
February 2017

Identification of a Ligand-Binding Site on the Staphylococcus aureus DnaG Primase C-Terminal Domain.

Biochemistry 2017 02 9;56(7):932-943. Epub 2017 Feb 9.

Department of Chemistry, University of Nebraska-Lincoln , Lincoln, Nebraska 68588-0304, United States.

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http://dx.doi.org/10.1021/acs.biochem.6b01273DOI Listing
February 2017

Amino Acid Catabolism in and the Function of Carbon Catabolite Repression.

MBio 2017 02 14;8(1). Epub 2017 Feb 14.

University of Nebraska Medical Center, Department of Pathology and Microbiology, Omaha, Nebraska, USA

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http://dx.doi.org/10.1128/mBio.01434-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312079PMC
February 2017

The NMR solution structure and function of RPA3313: a putative ribosomal transport protein from Rhodopseudomonas palustris.

Proteins 2017 01 13;85(1):93-102. Epub 2016 Nov 13.

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska, 68588-0304.

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http://dx.doi.org/10.1002/prot.25201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167650PMC
January 2017

Some axiomatic limitations for consensus and supertree functions on hierarchies.

J Theor Biol 2016 09 17;404:342-347. Epub 2016 Jun 17.

Department of Mathematics, University of Louisville, Louisville, KY 40292, United States.

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http://dx.doi.org/10.1016/j.jtbi.2016.06.016DOI Listing
September 2016

Redox Imbalance Underlies the Fitness Defect Associated with Inactivation of the Pta-AckA Pathway in Staphylococcus aureus.

J Proteome Res 2016 Apr 24;15(4):1205-12. Epub 2016 Mar 24.

Department of Chemistry, University of Nebraska-Lincoln , Lincoln, Nebraska 68588, United States.

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http://dx.doi.org/10.1021/acs.jproteome.5b01089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875753PMC
April 2016

A Urinary Metabolic Signature for Multiple Sclerosis and Neuromyelitis Optica.

J Proteome Res 2016 Feb 27;15(2):659-66. Epub 2016 Jan 27.

Department of Chemistry, University of Nebraska-Lincoln , Lincoln, Nebraska 68588-0304, United States.

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http://dx.doi.org/10.1021/acs.jproteome.5b01111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772670PMC
February 2016

PCA as a practical indicator of OPLS-DA model reliability.

Curr Metabolomics 2016;4(2):97-103

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0304.

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http://dx.doi.org/10.2174/2213235X04666160613122429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990351PMC
January 2016

Deterministic multidimensional nonuniform gap sampling.

J Magn Reson 2015 Dec 23;261:19-26. Epub 2015 Oct 23.

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0304, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jmr.2015.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970466PMC
December 2015

A Sequential Algorithm for Multiblock Orthogonal Projections to Latent Structures.

Chemometr Intell Lab Syst 2015 Dec;149(Pt B):33-39

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0304.

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http://dx.doi.org/10.1016/j.chemolab.2015.10.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668594PMC
December 2015

Simultaneous quantification of diazepam, flunitrazepam and metabolites in reinforced clostridial medium by liquid chromatography-tandem mass spectrometry.

J Anal Toxicol 2015 Jan-Feb;39(1):29-34. Epub 2014 Oct 13.

Department of Chemistry, West Virginia University, 1600 University Avenue, 208 Oglebay Hall, Morgantown, WV 26508, USA.

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http://dx.doi.org/10.1093/jat/bku110DOI Listing
October 2015

Transient sampling of aggregation-prone conformations causes pathogenic instability of a parkinsonian mutant of DJ-1 at physiological temperature.

Protein Sci 2015 Oct 17;24(10):1671-85. Epub 2015 Aug 17.

Department of Biochemistry and the Redox Biology Center, University of Nebraska-Lincoln, Lincoln, Nebraska, 68588.

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http://dx.doi.org/10.1002/pro.2762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594666PMC
October 2015

Statistical removal of background signals from high-throughput (1)H NMR line-broadening ligand-affinity screens.

J Biomol NMR 2015 Sep 9;63(1):53-8. Epub 2015 Jul 9.

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE, 68588-0304, USA.

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http://dx.doi.org/10.1007/s10858-015-9962-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577452PMC
September 2015

Generalized adaptive intelligent binning of multiway data.

Chemometr Intell Lab Syst 2015 Aug;146:42-46

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0304.

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http://dx.doi.org/10.1016/j.chemolab.2015.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456038PMC
August 2015

Follistatin-like 3 across gestation in preeclampsia and uncomplicated pregnancies among lean and obese women.

Reprod Sci 2015 Apr 3;22(4):402-9. Epub 2014 Apr 3.

Magee-Womens Research Institute and Foundation, University of Pittsburgh, Pittsburgh, PA, USA Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA, USA.

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http://journals.sagepub.com/doi/10.1177/1933719114529372
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http://dx.doi.org/10.1177/1933719114529372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812683PMC
April 2015

Arginine and asymmetric dimethylarginine in pregnant women with major depression.

Psychosom Med 2014 Jul-Aug;76(6):430-6

From the Department of Obstetrics & Gynecology and Reproductive Sciences (R.W.P.) and Magee-Womens Research Institute (A.R., M.G., R.W.P.), University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1097/PSY.0000000000000077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482344PMC
April 2015

Combining DI-ESI-MS and NMR datasets for metabolic profiling.

Metabolomics 2015 Apr;11(2):391-402

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0304 ; Redox Biology Center, University of Nebraska-Lincoln, Lincoln, NE 68583-0905.

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http://dx.doi.org/10.1007/s11306-014-0704-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354777PMC
April 2015

Urinary cortisol and depression in early pregnancy: role of adiposity and race.

BMC Pregnancy Childbirth 2015 Feb 13;15:30. Epub 2015 Feb 13.

Department of Obstetrics, Gynecology and Reproductive Sciences, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1186/s12884-015-0466-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335360PMC
February 2015

Production of human metabolites by gastrointestinal bacteria as a potential source of post-mortem alteration of antemortem drug/metabolite concentrations.

Drug Test Anal 2015 Jan 24;7(1):75-82. Epub 2014 Mar 24.

Edgewood Chemical Biological Center, E3400 Ricketts Point Road, Aberdeen Proving Ground, Gunpowder, 21010, MD, USA.

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http://doi.wiley.com/10.1002/dta.1647
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http://dx.doi.org/10.1002/dta.1647DOI Listing
January 2015

Functional evolution of PLP-dependent enzymes based on active-site structural similarities.

Proteins 2014 Oct 20;82(10):2597-608. Epub 2014 Jun 20.

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska, 68588-0304.

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http://dx.doi.org/10.1002/prot.24624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177364PMC
October 2014

Alterations in energy/redox metabolism induced by mitochondrial and environmental toxins: a specific role for glucose-6-phosphate-dehydrogenase and the pentose phosphate pathway in paraquat toxicity.

ACS Chem Biol 2014 Sep 7;9(9):2032-48. Epub 2014 Jul 7.

Departments of †Chemistry and ‡Biochemistry, §Redox Biology Center, and ∥School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln , Lincoln, Nebraska 68588, United States.

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http://dx.doi.org/10.1021/cb400894aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168797PMC
September 2014

Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia.

Cancer Metab 2014 1;2:18. Epub 2014 Sep 1.

The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE 68198, USA ; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198, USA ; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA ; Department of Genetic Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE 68198, USA.

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http://dx.doi.org/10.1186/2049-3002-2-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165433PMC
September 2014

The current state of drug discovery and a potential role for NMR metabolomics.

Authors:
Robert Powers

J Med Chem 2014 Jul 3;57(14):5860-70. Epub 2014 Mar 3.

Department of Chemistry, University of Nebraska-Lincoln , 722 Hamilton Hall, Lincoln, Nebraska 68588-0304, United States.

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http://dx.doi.org/10.1021/jm401803bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324437PMC
July 2014

Growth and preparation of Staphylococcus epidermidis for NMR metabolomic analysis.

Methods Mol Biol 2014 ;1106:71-91

School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE, USA.

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http://dx.doi.org/10.1007/978-1-62703-736-5_6DOI Listing
June 2014

Influence of iron and aeration on Staphylococcus aureus growth, metabolism, and transcription.

J Bacteriol 2014 Jun 4;196(12):2178-89. Epub 2014 Apr 4.

School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, USA

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http://jb.asm.org/cgi/doi/10.1128/JB.01475-14
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http://dx.doi.org/10.1128/JB.01475-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054190PMC
June 2014

MVAPACK: a complete data handling package for NMR metabolomics.

ACS Chem Biol 2014 May 7;9(5):1138-44. Epub 2014 Mar 7.

Department of Chemistry, University of Nebraska-Lincoln , Lincoln, Nebraska 68588-0304, United States.

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http://pubs.acs.org/doi/10.1021/cb4008937
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http://dx.doi.org/10.1021/cb4008937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033658PMC
May 2014

Vascular pool of releasable soluble VEGF receptor-1 (sFLT1) in women with previous preeclampsia and uncomplicated pregnancy.

J Clin Endocrinol Metab 2014 Mar 11;99(3):978-87. Epub 2013 Dec 11.

Division of Nephrology and Hypertension (T.L.W.), Mayo Clinic, Rochester, Minnesota 55905; Beth Israel Deaconess Medical Center (A.R.), Boston, Massachusetts 02215; Magee-Womens Research Institute (A.C.M., L.R.E., R.W.P., J.M.R., R.E.G., C.A.H.), and Department of Obstetrics, Gynecology, and Reproductive Sciences (R.W.P., J.M.R., C.A.H.), University of Pittsburgh, Pittsburgh, Pennsylvania 15213; Department of Environmental and Occupational Health (R.E.G., C.A.H.), and Department of Epidemiology (J.M.R.), Graduate School of Public Health (J.M.R.), University of Pittsburgh, Pittsburgh, Pennsylvania 15261; and Clinical and Translational Science Institute (J.M.R.), University of Pittsburgh, Pittsburgh, Pennsylvania 15260.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2013-3277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942228PMC
March 2014

Structure and function of human DnaJ homologue subfamily a member 1 (DNAJA1) and its relationship to pancreatic cancer.

Biochemistry 2014 Mar 19;53(8):1360-72. Epub 2014 Feb 19.

Department of Chemistry, University of Nebraska-Lincoln , Lincoln, Nebraska 68588, United States.

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http://pubs.acs.org/doi/10.1021/bi401329a
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http://dx.doi.org/10.1021/bi401329aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985919PMC
March 2014

Metabolomics analysis identifies d-Alanine-d-Alanine ligase as the primary lethal target of d-Cycloserine in mycobacteria.

J Proteome Res 2014 Feb 13;13(2):1065-76. Epub 2013 Dec 13.

Department of Chemistry, University of Nebraska-Lincoln , Lincoln, Nebraska 68588-0304, United States.

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http://pubs.acs.org/doi/10.1021/pr4010579
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http://dx.doi.org/10.1021/pr4010579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975674PMC
February 2014

Simultaneous Phase and Scatter Correction for NMR Datasets.

Chemometr Intell Lab Syst 2014 Feb;131:1-6

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0304.

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http://dx.doi.org/10.1016/j.chemolab.2013.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907089PMC
February 2014

Revisiting Protocols for the NMR Analysis of Bacterial Metabolomes.

J Integr OMICS 2013 Dec;3(2):120-137

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0304.

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http://dx.doi.org/10.5584/jiomics.v3i2.139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465129PMC
December 2013

Inactivation of the Pta-AckA pathway causes cell death in Staphylococcus aureus.

J Bacteriol 2013 Jul 26;195(13):3035-44. Epub 2013 Apr 26.

Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.

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http://dx.doi.org/10.1128/JB.00042-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697545PMC
July 2013

Redefining preeclampsia using placenta-derived biomarkers.

Hypertension 2013 May 4;61(5):932-42. Epub 2013 Mar 4.

Oslo University Hospital, Ullevål, Kirkeveien 166, Oslo 0450, Norway.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.111.00250DOI Listing
May 2013

Utilities for quantifying separation in PCA/PLS-DA scores plots.

Anal Biochem 2013 Feb 15;433(2):102-4. Epub 2012 Oct 15.

Department of Chemistry, University of Nebraska-Lincoln, NE 68588-0304, USA.

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http://dx.doi.org/10.1016/j.ab.2012.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534867PMC
February 2013

13C NMR reveals no evidence of n-π* interactions in proteins.

PLoS One 2012 2;7(8):e42075. Epub 2012 Aug 2.

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410932PMC
January 2013

Multivariate Analysis in Metabolomics.

Curr Metabolomics 2013;1(1):92-107

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0304.

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http://dx.doi.org/10.2174/2213235X11301010092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465187PMC
January 2013

NMR Metabolomics Analysis of Parkinson's Disease.

Curr Metabolomics 2013;1(3):191-209

University of Nebraska-Lincoln, Department of Chemistry, 722 Hamilton Hall, Lincoln, NE 68588-0304.

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http://dx.doi.org/10.2174/2213235X113019990004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465192PMC
January 2013

The applicability of molecular descriptors for designing an electrospray ionization mass spectrometry compatible library for drug discovery.

Comb Chem High Throughput Screen 2012 Dec;15(10):806-15

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0304, USA.

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December 2012

Application of NMR metabolomics to search for human disease biomarkers.

Comb Chem High Throughput Screen 2012 Sep;15(8):595-610

Department of Chemistry, University of Nebraska-Lincoln, 722 Hamilton Hall, Lincoln, NE 68588- 0304, USA.

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September 2012

Sample preparation of Mycobacterium tuberculosis extracts for nuclear magnetic resonance metabolomic studies.

J Vis Exp 2012 Sep 3(67):e3673. Epub 2012 Sep 3.

School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485063PMC
September 2012

Low placental growth factor across pregnancy identifies a subset of women with preterm preeclampsia: type 1 versus type 2 preeclampsia?

Hypertension 2012 Jul 29;60(1):239-46. Epub 2012 May 29.

Department of Obstetrics, Gynecology, and Reproductive SciencesMagee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.112.191213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578235PMC
July 2012

Application of NMR and molecular docking in structure-based drug discovery.

Top Curr Chem 2012 ;326:1-34

Department of Chemistry, University of Nebraska, Lincoln, NE 68588-0304, USA.

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http://dx.doi.org/10.1007/128_2011_213DOI Listing
June 2012

An exploratory factor analysis of nutritional biomarkers associated with major depression in pregnancy.

Public Health Nutr 2012 Jun 8;15(6):1078-86. Epub 2011 Dec 8.

Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, A742 Crabtree Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA.

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http://www.journals.cambridge.org/abstract_S1368980011002904
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309065PMC
June 2012

Analysis of bacterial biofilms using NMR-based metabolomics.

Future Med Chem 2012 Jun;4(10):1273-306

Department of Chemistry, University of Nebraska-Lincoln, 722 Hamilton Hall, Lincoln, NE 68588-0304, USA.

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http://www.future-science.com/doi/10.4155/fmc.12.59
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564560PMC
June 2012

¹H, ¹³C, and ¹⁵N NMR assignments for the helicase interaction domain of Staphylococcus aureus DnaG primase.

Biomol NMR Assign 2012 Apr 7;6(1):35-8. Epub 2011 Jun 7.

Department of Chemistry, University of Nebraska-Lincoln, 721 Hamilton Hall, Lincoln, NE 68588-0304, USA.

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http://link.springer.com/10.1007/s12104-011-9320-7
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April 2012

Haptoglobin phenotype, angiogenic factors, and preeclampsia risk.

Am J Obstet Gynecol 2012 Apr 13;206(4):358.e10-8. Epub 2012 Jan 13.

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.ajog.2012.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319170PMC
April 2012

Semantically enabling pharmacogenomic data for the realization of personalized medicine.

Pharmacogenomics 2012 Jan;13(2):201-12

Department of Medical Statistics & Bioinformatics, Leiden University Medical Center/Informatics Institute, University of Amsterdam, Einthovenweg 20, 2333 ZC Leiden, The Netherlands.

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http://dx.doi.org/10.2217/pgs.11.179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957334PMC
January 2012

An inexpensive high-throughput nuclear magnetic resonance tube cleaning apparatus.

Anal Biochem 2011 Sep 17;416(2):234-6. Epub 2011 May 17.

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.

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http://dx.doi.org/10.1016/j.ab.2011.05.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138807PMC
September 2011

Caffeine and insulin resistance in pregnancy.

Am J Perinatol 2011 Aug 4;28(7):571-8. Epub 2011 Mar 4.

Department of Obstetrics, Gynecology and Reproductive Services, University of Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1055/s-0031-1274511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116064PMC
August 2011

NMR analysis of a stress response metabolic signaling network.

J Proteome Res 2011 Aug 8;10(8):3743-54. Epub 2011 Jul 8.

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588-0304, USA.

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http://dx.doi.org/10.1021/pr200360wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153081PMC
August 2011

Cardiovascular system during the postpartum state in women with a history of preeclampsia.

Hypertension 2011 Jul 23;58(1):57-62. Epub 2011 May 23.

Department of Bioengineering, University of Pittsburgh, 300 Technology Dr, 306 Center for Bioengineering, Pittsburgh, PA 15219, USA.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.111.173278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139979PMC
July 2011

Correlation between protein function and ligand binding profiles.

J Proteome Res 2011 May 22;10(5):2538-45. Epub 2011 Mar 22.

Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588-0304, United States.

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http://dx.doi.org/10.1021/pr200015dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090486PMC
May 2011

Research in bioanalysis and separations at the University of Nebraska - Lincoln.

Bioanalysis 2011 May;3(10):1065-76

Chemistry Department, University of Nebraska - Lincoln, NE 68588-0304, USA.

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http://dx.doi.org/10.4155/bio.11.64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134374PMC
May 2011

Bacterial protein structures reveal phylum dependent divergence.

Comput Biol Chem 2011 Feb 18;35(1):24-33. Epub 2011 Jan 18.

Department of Chemistry, University of Nebraska-Lincoln, 68588-0304, United States.

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http://dx.doi.org/10.1016/j.compbiolchem.2010.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049983PMC
February 2011

The Role of Obesity in Preeclampsia.

Pregnancy Hypertens 2011 Jan;1(1):6-16

Magee-Womens Research Institute, University of Pittsburgh.

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https://linkinghub.elsevier.com/retrieve/pii/S22107789100001
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http://dx.doi.org/10.1016/j.preghy.2010.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082136PMC
January 2011