Publications by authors named "Ren-Ke Li"

232Publications

Understanding systemic factors in aging and rejuvenation.

Authors:
Faisal J Alibhai Ren-Ke Li

Aging (Albany NY) 2020 11 13;12(21):20936-20937. Epub 2020 Nov 13.

Toronto General Hospital Research Institute, Division of Cardiovascular Surgery, University Health Network, Toronto, Ontario, Canada.

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November 2020

Transplanted microvessels improve pluripotent stem cell-derived cardiomyocyte engraftment and cardiac function after infarction in rats.

Authors:
Xuetao Sun Jun Wu Beiping Qiang Rocco Romagnuolo Mark Gagliardi Gordon Keller Michael A Laflamme Ren-Ke Li Sara S Nunes

Sci Transl Med 2020 Sep;12(562)

Toronto General Hospital Research Institute, University Health Network, 101 College St., Toronto, ON M5G 1L7, Canada.

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September 2020

Evidence for the existence of CD34 angiogenic stem cells in human first-trimester decidua and their therapeutic for ischaemic heart disease.

Authors:
Long Bai Lu Sun Wei Chen Kai-Yu Liu Chun-Feng Zhang Fei Wang Gui-Huan Zhang Ye Huang Jing-Xuan Li Ying Gao Xin Sun Wei Liu Guo-Qing Du Ren-Ke Li Ming-Li Huang Hai Tian

J Cell Mol Med 2020 Oct 8;24(20):11837-11848. Epub 2020 Sep 8.

Department of Cardiovascular Surgery, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.

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October 2020

Considering Cause and Effect of Immune Cell Aging on Cardiac Repair after Myocardial Infarction.

Authors:
Stephanie W Tobin Faisal J Alibhai Richard D Weisel Ren-Ke Li

Cells 2020 08 13;9(8). Epub 2020 Aug 13.

Division of Cardiovascular Surgery, Toronto General Hospital Research Institute, University Health Network, Toronto, ON M5T 1P5, Canada.

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August 2020

The conductive function of biopolymer corrects myocardial scar conduction blockage and resynchronizes contraction to prevent heart failure.

Authors:
Sheng He Jun Wu Shu-Hong Li Li Wang Yu Sun Jun Xie Daniel Ramnath Richard D Weisel Terrence M Yau Hsing-Wen Sung Ren-Ke Li

Biomaterials 2020 Nov 3;258:120285. Epub 2020 Aug 3.

Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada; Division of Cardiovascular Surgery, Department of Surgery, University Health Network and University of Toronto, Toronto, Canada. Electronic address:

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November 2020

Knock-out of MicroRNA 145 impairs cardiac fibroblast function and wound healing post-myocardial infarction.

Authors:
Hui-Fang Song Sheng He Shu-Hong Li Jun Wu Wenjuan Yin Zhengbo Shao Guo-Qing Du Jie Wu Jiao Li Richard D Weisel Subodh Verma Jun Xie Ren-Ke Li

J Cell Mol Med 2020 Aug 6;24(16):9409-9419. Epub 2020 Jul 6.

Toronto General Research Institute, University Health Network, Toronto, ON, Canada.

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August 2020

Rectification of radiotherapy-induced cognitive impairments in aged mice by reconstituted Sca-1 stem cells from young donors.

Authors:
Lukasz Wlodarek Feng Cao Faisal J Alibhai Adam Fekete Nima Noyan Stephanie W Tobin Tina B Marvasti Jun Wu Shu-Hong Li Richard D Weisel Lu-Yang Wang Zhengping Jia Ren-Ke Li

J Neuroinflammation 2020 Feb 7;17(1):51. Epub 2020 Feb 7.

Toronto General Hospital Research Institute, University Health Network, Toronto Medical Discovery Tower, Room 3-702, 101 College Street, Toronto, Ontario, M5G 1L7, Canada.

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February 2020

Targeting aged bone marrow for systemic rejuvenation.

Authors:
Faisal J Alibhai Ren-Ke Li

Aging (Albany NY) 2020 02 6;12(3):2024-2025. Epub 2020 Feb 6.

Toronto General Hospital Research Institute, Toronto General Hospital, Toronto, ON, Canada.

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February 2020

Cellular senescence contributes to age-dependent changes in circulating extracellular vesicle cargo and function.

Authors:
Faisal J Alibhai Fievel Lim Azadeh Yeganeh Peter V DiStefano Tina Binesh-Marvasti Alyssa Belfiore Lukasz Wlodarek Dakota Gustafson Sean Millar Shu-Hong Li Richard D Weisel Jason E Fish Ren-Ke Li

Aging Cell 2020 03 21;19(3):e13103. Epub 2020 Jan 21.

Toronto General Hospital Research Institute, Toronto General Hospital, Toronto, ON, Canada.

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March 2020

A conductive cell-delivery construct as a bioengineered patch that can improve electrical propagation and synchronize cardiomyocyte contraction for heart repair.

Authors:
Shanglin Chen Meng-Hsuan Hsieh Shu-Hong Li Jun Wu Richard D Weisel Yen Chang Hsing-Wen Sung Ren-Ke Li

J Control Release 2020 04 17;320:73-82. Epub 2020 Jan 17.

Toronto General Hospital Research Institute, Division of Cardiovascular Surgery, University Health Network, Toronto, Canada; Division of Cardiac Surgery, Department of Surgery, University of Toronto, Toronto, Canada. Electronic address:

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April 2020

A self-doping conductive polymer hydrogel that can restore electrical impulse propagation at myocardial infarct to prevent cardiac arrhythmia and preserve ventricular function.

Authors:
Chongyu Zhang Meng-Hsuan Hsieh Song-Yi Wu Shu-Hong Li Jun Wu Shi-Ming Liu Hao-Ji Wei Richard D Weisel Hsing-Wen Sung Ren-Ke Li

Biomaterials 2020 02 9;231:119672. Epub 2019 Dec 9.

Toronto General Hospital Research Institute, Division of Cardiovascular Surgery, University Health Network, Toronto, Canada; Division of Cardiac Surgery, Department of Surgery, University of Toronto, Toronto, Canada. Electronic address:

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February 2020

Protective role of Nrf2 against ischemia reperfusion injury and cardiac allograft vasculopathy.

Authors:
Naoto Fukunaga Hiroyuki Kawajiri Mitesh V Badiwala Jagdish Butany Ren-Ke Li Filio Billia Vivek Rao

Am J Transplant 2020 05 3;20(5):1262-1271. Epub 2020 Jan 3.

Division of Cardiovascular Surgery, Peter Munk Cardiac Centre, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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May 2020

Mesenchymal Stromal Cells from Patients with Cyanotic Congenital Heart Disease are Optimal Candidate for Cardiac Tissue Engineering.

Authors:
Kai Kang Jun-Bo Chuai Bao-Dong Xie Jian-Zhong Li Hui Qu Hua Wu Shao-Hong Fang Jin-Jin Cui Li-Li Xiu Jin-Cheng Han Tian-Hui Cao Xiao-Ping Leng Hai Tian Ren-Ke Li Shu-Lin Jiang

Biomaterials 2020 02 6;230:119574. Epub 2019 Nov 6.

Department of Cardiovascular Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China; The Key Laboratory of Myocardial Ischemia, Harbin Medical University, Ministry of Education, Heilongjiang Province, China. Electronic address:

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February 2020

CD34 Stem Cells: Promising Roles in Cardiac Repair and Regeneration.

Authors:
Tina Binesh Marvasti Faisal J Alibhai Richard D Weisel Ren-Ke Li

Can J Cardiol 2019 10 11;35(10):1311-1321. Epub 2019 Jun 11.

Toronto General Hospital Research Institute, Division of Cardiovascular Surgery, University Health Network, Toronto, Ontario, Canada; Division of Cardiac Surgery, Department of Surgery, University of Toronto; Toronto, Ontario, Canada. Electronic address:

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October 2019

Long-term repopulation of aged bone marrow stem cells using young Sca-1 cells promotes aged heart rejuvenation.

Authors:
Jiao Li Shu-Hong Li Jun Dong Faisal J Alibhai Chongyu Zhang Zheng-Bo Shao Hui-Fang Song Sheng He Wen-Juan Yin Jun Wu Richard D Weisel Shi-Ming Liu Ren-Ke Li

Aging Cell 2019 12 5;18(6):e13026. Epub 2019 Aug 5.

Division of Cardiovascular Surgery, Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.

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December 2019

Effect of neuron-derived neurotrophic factor on rejuvenation of human adipose-derived stem cells for cardiac repair after myocardial infarction.

Authors:
Kun Yang Hui-Fang Song Sheng He Wen-Juan Yin Xue-Mei Fan Feng Ru Hui Gong Xiao-Yan Zhai Jie Zhang Ze-Xu Peng Guang-Xia Xi Jun Xie Ren-Ke Li

J Cell Mol Med 2019 09 9;23(9):5981-5993. Epub 2019 Jul 9.

Division of Cardiovascular Surgery, Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada.

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September 2019

Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate the Infarcted Pig Heart but Induce Ventricular Tachyarrhythmias.

Authors:
Rocco Romagnuolo Hassan Masoudpour Andreu Porta-Sánchez Beiping Qiang Jennifer Barry Andrew Laskary Xiuling Qi Stéphane Massé Karl Magtibay Hiroyuki Kawajiri Jun Wu Tamilla Valdman Sadikov Janet Rothberg Krishna M Panchalingam Emily Titus Ren-Ke Li Peter W Zandstra Graham A Wright Kumaraswamy Nanthakumar Nilesh R Ghugre Gordon Keller Michael A Laflamme

Stem Cell Reports 2019 05 2;12(5):967-981. Epub 2019 May 2.

McEwen Stem Cell Institute, University Health Network, Toronto, ON M5G 1L7, Canada; Peter Munk Cardiac Centre, University Health Network, Toronto, ON M5G 2N2, Canada; University of Toronto, Toronto, ON M5G 1L7, Canada. Electronic address:

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May 2019

Knockout of Canopy 2 activates p16 pathway to impair cardiac repair.

Authors:
Wenjuan Yin Jian Guo Chongyu Zhang Faisal J Alibhai Shu-Hong Li Phyllis Billia Jun Wu Terrence M Yau Richard D Weisel Ren-Ke Li

J Mol Cell Cardiol 2019 07 29;132:36-48. Epub 2019 Apr 29.

Toronto General Hospital Research Institute, Division of Cardiovascular Surgery, University Health Network, Toronto, ON, Canada; Division of Cardiac Surgery, Department of Surgery, University of Toronto, Toronto, ON, Canada. Electronic address:

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July 2019

Novel mediators of aneurysm progression in bicuspid aortic valve disease.

Authors:
Stephanie W Tobin Faisal J Alibhai Myunghyun M Lee Azadeh Yeganeh Jie Wu Shu-Hong Li Jian Guo Katherine Tsang Laura Tumiati Rodolfo Rocha Jagdish Butany Terrence M Yau Maral Ouzounian Tirone E David Richard D Weisel Ren-Ke Li

J Mol Cell Cardiol 2019 07 29;132:71-83. Epub 2019 Apr 29.

Division of Cardiovascular Surgery, Toronto General Hospital Research Institute and Peter Munk Cardiac Centre, University Health Network, Toronto, ON, Canada; Department of Surgery, Division of Cardiac Surgery, University of Toronto, Toronto, ON, Canada. Electronic address:

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July 2019

Commentary: Circulating factors released after myocardial infarction: Beneficial or detrimental?

Authors:
Faisal J Alibhai Ren-Ke Li

J Thorac Cardiovasc Surg 2019 06 8;157(6):2270-2271. Epub 2018 Nov 8.

Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada; Division of Cardiac Surgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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June 2019