Reijo Laaksonen

Reijo Laaksonen

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Reijo Laaksonen

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Dedifferentiation of Primary Hepatocytes is Accompanied with Reorganization of Lipid Metabolism Indicated by Altered Molecular Lipid and miRNA Profiles.

Int J Mol Sci 2019 Jun 14;20(12). Epub 2019 Jun 14.

BioMediTech, Faculty of Medicine and Health Technology, Tampere University, 33520 Tampere, Finland.

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http://dx.doi.org/10.3390/ijms20122910DOI Listing
June 2019

Whole blood microRNA levels associate with glycemic status and correlate with target mRNAs in pathways important to type 2 diabetes.

Sci Rep 2019 Jun 20;9(1):8887. Epub 2019 Jun 20.

Department of Clinical Chemistry, Pirkanmaa Hospital District, Fimlab Laboratories, and the Finnish Cardiovascular Research Center, Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

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http://dx.doi.org/10.1038/s41598-019-43793-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586838PMC
June 2019

Association of Plasma Ceramides With Myocardial Perfusion in Patients With Coronary Artery Disease Undergoing Stress Myocardial Perfusion Scintigraphy.

Arterioscler Thromb Vasc Biol 2018 12;38(12):2854-2861

From the Section of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Italy (A.M., G.T.).

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http://dx.doi.org/10.1161/ATVBAHA.118.311927DOI Listing
December 2018

PCSK9 inhibition alters the lipidome of plasma and lipoprotein fractions.

Atherosclerosis 2018 02 12;269:159-165. Epub 2018 Jan 12.

Genentech, Development Sciences, 1 DNA Way MS 46-1A, South San Francisco, CA, 94080, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00219150183000
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http://dx.doi.org/10.1016/j.atherosclerosis.2018.01.004DOI Listing
February 2018

Differentially expressed genes and canonical pathways in the ascending thoracic aortic aneurysm - The Tampere Vascular Study.

Sci Rep 2017 09 21;7(1):12127. Epub 2017 Sep 21.

Department of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1038/s41598-017-12421-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608723PMC
September 2017

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.

Authors:
Stephen Zewinger Marcus E Kleber Vinicius Tragante Raymond O McCubrey Amand F Schmidt Kenan Direk Ulrich Laufs Christian Werner Wolfgang Koenig Dietrich Rothenbacher Ute Mons Lutz P Breitling Herrmann Brenner Richard T Jennings Ioannis Petrakis Sarah Triem Mira Klug Alexandra Filips Stefan Blankenberg Christoph Waldeyer Christoph Sinning Renate B Schnabel Karl J Lackner Efthymia Vlachopoulou Ottar Nygård Gard Frodahl Tveitevåg Svingen Eva Ringdal Pedersen Grethe S Tell Juha Sinisalo Markku S Nieminen Reijo Laaksonen Stella Trompet Roelof A J Smit Naveed Sattar J Wouter Jukema Heinrich V Groesdonk Graciela Delgado Tatjana Stojakovic Anna P Pilbrow Vicky A Cameron A Mark Richards Robert N Doughty Yan Gong Rhonda Cooper-DeHoff Julie Johnson Markus Scholz Frank Beutner Joachim Thiery J Gustav Smith Ragnar O Vilmundarson Ruth McPherson Alexandre F R Stewart Sharon Cresci Petra A Lenzini John A Spertus Oliviero Olivieri Domenico Girelli Nicola I Martinelli Andreas Leiherer Christoph H Saely Heinz Drexel Axel Mündlein Peter S Braund Christopher P Nelson Nilesh J Samani Daniel Kofink Imo E Hoefer Gerard Pasterkamp Arshed A Quyyumi Yi-An Ko Jaana A Hartiala Hooman Allayee W H Wilson Tang Stanley L Hazen Niclas Eriksson Claes Held Emil Hagström Lars Wallentin Axel Åkerblom Agneta Siegbahn Igor Karp Christopher Labos Louise Pilote James C Engert James M Brophy George Thanassoulis Peter Bogaty Wojciech Szczeklik Marcin Kaczor Marek Sanak Salim S Virani Christie M Ballantyne Vei-Vei Lee Eric Boerwinkle Michael V Holmes Benjamin D Horne Aroon Hingorani Folkert W Asselbergs Riyaz S Patel Bernhard K Krämer Hubert Scharnagl Danilo Fliser Winfried März Thimoteus Speer

Lancet Diabetes Endocrinol 2017 07 26;5(7):534-543. Epub 2017 May 26.

Department of Internal Medicine IV, Saarland University Hospital, Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/S2213-8587(17)30096-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651679PMC
July 2017

Circulating Ceramides Predict Cardiovascular Outcomes in the Population-Based FINRISK 2002 Cohort.

Arterioscler Thromb Vasc Biol 2016 Dec 20;36(12):2424-2430. Epub 2016 Oct 20.

From the Department of Health, National Institute for Health and Welfare, Helsinki, Finland (A.S.H., V.S.); Zora Biosciences Oy, Espoo, Finland (M.S.-A., M.H., D.K., R.H., K.E., R.L.); Medical School, University of Tampere, Finland (R.L.); and Finnish Clinical Biobank, University Hospital of Tampere, Finland (R.L.).

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http://dx.doi.org/10.1161/ATVBAHA.116.307497DOI Listing
December 2016

FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders.

Neurology 2016 Nov 28;87(22):2290-2299. Epub 2016 Oct 28.

From the Research Programs Unit, Molecular Neurology (J.M.L., S.F., H.L., M.A., P.I.), Faculty of Medicine/Clinicum, Oncology (P.O.), and Finland Genome Scale Biology Program (S.L.), University of Helsinki, Finland; Mitochondrial Medicine Group (E.B., C.V., M.Z.), Medical Research Council Mitochondrial Biology Unit, Cambridge, UK; Center for Physiology and Pathophysiology (O.R.B., R.J.W.), Institute of Vegetative Physiology, University of Köln, Germany; Transplantation and Liver Surgery Clinic (H.I., K.H.), Department of Oncology (P.O., S.L.), and Heart and Lung Center, Department of Cardiology (T.H.), Helsinki University Hospital; School of Medicine (M.H., J.J., R.L.), University of Tampere; Anaesthesiology, Intensive Care and Pain Medicine (R.M.), Clinical Neurosciences, Neurology (H.L., M.A., A.S.), and Child Neurology, Children's Hospital (P.I.), University of Helsinki and Helsinki University Hospital, Finland; Dyslipidemia Center (G.M.), Cardiotoracovascular Department, Niguarda Hospital, Milan, Italy; PEDEGO Research Unit (J.U.) and Biocenter Oulu (J.U.), University of Oulu; Finnish Clinical Biobank Tampere (R.L.), Tampere University Hospital, Finland; Nijmegen Centre for Mitochondrial Disorders (J.S.), Radboud University Medical Centre, Nijmegen, the Netherlands; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD) (R.J.W.), Köln; Center for Molecular Medicine Cologne (R.J.W.), CMMC, University of Köln, Germany; Faculty of Life and Environmental Sciences (K.N.), University of Tsukuba, Japan; and Medical Research Center Oulu (J.U.), Oulu University Hospital and University of Oulu, Finland.

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http://dx.doi.org/10.1212/WNL.0000000000003374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270510PMC
November 2016

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis.

Sci Rep 2016 10 12;6:35278. Epub 2016 Oct 12.

Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.1038/srep35278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059659PMC
October 2016

Use and role of monoclonal antibodies and other biologics in preventive cardiology.

Swiss Med Wkly 2015 2;145:w14179. Epub 2015 Nov 2.

Cardiology Division, Geneva University Hospitals, Switzerland.

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http://dx.doi.org/10.4414/smw.2015.14179DOI Listing
June 2016

Fast and Accurate Construction of Confidence Intervals for Heritability.

Am J Hum Genet 2016 06;98(6):1181-1192

Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv 6997801, Israel; Molecular Microbiology and Biotechnology Department, Tel Aviv University, Tel Aviv 6997801, Israel; International Computer Science Institute, 1947 Center Street, Berkeley, CA 94704, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908190PMC
June 2016

Development and validation of a high-throughput LC-MS/MS assay for routine measurement of molecular ceramides.

Anal Bioanal Chem 2016 May 27;408(13):3475-83. Epub 2016 Feb 27.

Zora Biosciences, Biologinkuja 1, 02150, Espoo, Finland.

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http://dx.doi.org/10.1007/s00216-016-9425-zDOI Listing
May 2016

Differential network analysis with multiply imputed lipidomic data.

PLoS One 2015 30;10(3):e0121449. Epub 2015 Mar 30.

Department of Bioinformatics and Biostatistics, University of Louisville, Louisville, Kentucky, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121449PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378983PMC
April 2016

Identifying new Risk Markers and Potential Targets for Coronary Artery Disease: The Value of the Lipidome and Metabolome.

Authors:
Reijo Laaksonen

Cardiovasc Drugs Ther 2016 Feb;30(1):19-32

Zora Biosciences Oy, Biologinkuja 1, 02150, Espoo, FI, Finland.

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http://dx.doi.org/10.1007/s10557-016-6651-8DOI Listing
February 2016

Fish oil and krill oil differentially modify the liver and brain lipidome when fed to mice.

Lipids Health Dis 2015 Aug 11;14:88. Epub 2015 Aug 11.

Division of Clinical Chemistry, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, S-14186, Stockholm, Sweden.

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http://www.lipidworld.com/content/14/1/88
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http://dx.doi.org/10.1186/s12944-015-0086-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531896PMC
August 2015

Abnormal splicing of NEDD4 in myotonic dystrophy type 2: possible link to statin adverse reactions.

Am J Pathol 2014 Aug 5;184(8):2322-32. Epub 2014 Jun 5.

Folkhälsan Institute of Genetics and Department of Medical Genetics, Haartman Institute, University of Helsinki, Helsinki, Finland; Neuromuscular Research Centre, Department of Neurology, University Hospital and University of Tampere, Tampere, Finland; Department of Neurology, Vaasa Central Hospital, Vaasa, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116696PMC
August 2014

EPIQ-efficient detection of SNP-SNP epistatic interactions for quantitative traits.

Bioinformatics 2014 Jun;30(12):i19-25

The Blavatnik School of Computer Science, Tel Aviv University, Tel-Aviv 69978, Israel, V Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Mannheim D-68167, Germany, Zora Biosciences Oy, Espoo 02150, Finland, Medical School, University of Tampere, Tampere 33104, Finland, Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz A-8036, Austria, Synlab Academy, Synlab Services GmbH, Mannheim D-68165, Germany, Department of Molecular Microbiology and Biotechnology, George Wise Faculty of Life Science, Tel-Aviv University, Tel-Aviv 69978, Israel and International Computer Science Institute, Berkeley, CA 94704, USAThe Blavatnik School of Computer Science, Tel Aviv University, Tel-Aviv 69978, Israel, V Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Mannheim D-68167, Germany, Zora Biosciences Oy, Espoo 02150, Finland, Medical School, University of Tampere, Tampere 33104, Finland, Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz A-8036, Austria, Synlab Academy, Synlab Services GmbH, Mannheim D-68165, Germany, Department of Molecular Microbiology and Biotechnology, George Wise Faculty of Life Science, Tel-Aviv University, Tel-Aviv 69978, Israel and International Computer Science Institute, Berkeley, CA 94704, USAThe Blavatnik School of Computer Science, Tel Aviv University, Tel-Aviv 69978, Israel, V Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Mannheim D-68167, Germany, Zora Biosciences Oy, Espoo 02150, Finland, Medical School, University of Tampere, Tampere 33104, Finland, Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz A-803

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http://dx.doi.org/10.1093/bioinformatics/btu261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229902PMC
June 2014

Drug-induced rhabdomyolysis: from systems pharmacology analysis to biochemical flux.

Chem Res Toxicol 2014 Mar 28;27(3):421-32. Epub 2014 Jan 28.

Department of Neurology, University of Michigan , Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/tx400409cDOI Listing
March 2014

Lipidomics in drug discovery.

Drug Discov Today 2014 Feb 17;19(2):164-70. Epub 2013 Sep 17.

Zora Biosciences Oy, Biologinkuja 1, 02150 Espoo, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2013.09.008DOI Listing
February 2014

Molecular lipids identify cardiovascular risk and are efficiently lowered by simvastatin and PCSK9 deficiency.

J Clin Endocrinol Metab 2014 Jan 20;99(1):E45-52. Epub 2013 Dec 20.

Zora Biosciences (K.T., K.E., M.S., D.K., T.S., R.H., R.L.), Biologinkuja 1, FI-02150 Espoo, Finland; University Hospital (R.L.), FI-33521 Tampere, Finland; Department of Clinical Pharmacology (K.T., R.L.), University of Helsinki, FI-00290 Helsinki, Finland; Center for Endocrinology, Diabetes, and Preventive Medicine (I.G.-B.), University of Cologne, D-50937 Cologne, Germany; Evangelical Geriatrics Center Berlin (H.K.B.), Charité University Medicine Berlin, D-13347, Berlin, Germany; Medical Clinic V, (M.E.K., W.M.), Medical Faculty Mannheim, University of Heidelberg, 69115 Heidelberg; Synlab Academy (W.M.), Synlab Services GmbH, D-68165 Mannheim, Germany; and Clinical Institute of Medical and Clinical Laboratory Diagnostics (W.M.), Medical University of Graz, 8036 Graz, Austria.

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http://dx.doi.org/10.1210/jc.2013-2559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928964PMC
January 2014

Association of neuroimmune guidance cue netrin-1 and its chemorepulsive receptor UNC5B with atherosclerotic plaque expression signatures and stability in human(s): Tampere Vascular Study (TVS).

Circ Cardiovasc Genet 2013 Dec 11;6(6):579-87. Epub 2013 Oct 11.

Department of Clinical Chemistry, Institute of Biomedical Technology and BioMediTech, and Department of Pathology, Fimlab Laboratories, University of Tampere and Tampere University Hospital, Tampere, Finland; and Division of Vascular Surgery, Department of Surgery and Heart Center, and Department of Clinical Physiology, Tampere University Hospital, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1161/CIRCGENETICS.113.000141DOI Listing
December 2013

STOMPing forward: statins, muscle complaints and CK.

Authors:
Reijo Laaksonen

Atherosclerosis 2013 Oct 2;230(2):256-7. Epub 2013 Aug 2.

Zora Biosciences, Biologinkuja 1, 02150 Espoo, Finland; Science Center, Tampere University Hospital, Tampere, Finland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00219150130044
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http://dx.doi.org/10.1016/j.atherosclerosis.2013.07.044DOI Listing
October 2013

A comparison of the accuracy of Illumina HumanHT-12 v3 Expression BeadChip and TaqMan qRT-PCR gene expression results in patient samples from the Tampere Vascular Study.

Atherosclerosis 2013 Jan 12;226(1):149-52. Epub 2012 Nov 12.

Department of Clinical Chemistry, Tampere University Hospital, Fimlab Laboratories and University of Tampere, School of Medicine, Finland.

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http://dx.doi.org/10.1016/j.atherosclerosis.2012.10.078DOI Listing
January 2013

Large-scale association analysis identifies new risk loci for coronary artery disease.

Authors:
Panos Deloukas Stavroula Kanoni Christina Willenborg Martin Farrall Themistocles L Assimes John R Thompson Erik Ingelsson Danish Saleheen Jeanette Erdmann Benjamin A Goldstein Kathleen Stirrups Inke R König Jean-Baptiste Cazier Asa Johansson Alistair S Hall Jong-Young Lee Cristen J Willer John C Chambers Tõnu Esko Lasse Folkersen Anuj Goel Elin Grundberg Aki S Havulinna Weang K Ho Jemma C Hopewell Niclas Eriksson Marcus E Kleber Kati Kristiansson Per Lundmark Leo-Pekka Lyytikäinen Suzanne Rafelt Dmitry Shungin Rona J Strawbridge Gudmar Thorleifsson Emmi Tikkanen Natalie Van Zuydam Benjamin F Voight Lindsay L Waite Weihua Zhang Andreas Ziegler Devin Absher David Altshuler Anthony J Balmforth Inês Barroso Peter S Braund Christof Burgdorf Simone Claudi-Boehm David Cox Maria Dimitriou Ron Do Alex S F Doney NourEddine El Mokhtari Per Eriksson Krista Fischer Pierre Fontanillas Anders Franco-Cereceda Bruna Gigante Leif Groop Stefan Gustafsson Jörg Hager Göran Hallmans Bok-Ghee Han Sarah E Hunt Hyun M Kang Thomas Illig Thorsten Kessler Joshua W Knowles Genovefa Kolovou Johanna Kuusisto Claudia Langenberg Cordelia Langford Karin Leander Marja-Liisa Lokki Anders Lundmark Mark I McCarthy Christa Meisinger Olle Melander Evelin Mihailov Seraya Maouche Andrew D Morris Martina Müller-Nurasyid Kjell Nikus John F Peden N William Rayner Asif Rasheed Silke Rosinger Diana Rubin Moritz P Rumpf Arne Schäfer Mohan Sivananthan Ci Song Alexandre F R Stewart Sian-Tsung Tan Gudmundur Thorgeirsson C Ellen van der Schoot Peter J Wagner George A Wells Philipp S Wild Tsun-Po Yang Philippe Amouyel Dominique Arveiler Hanneke Basart Michael Boehnke Eric Boerwinkle Paolo Brambilla Francois Cambien Adrienne L Cupples Ulf de Faire Abbas Dehghan Patrick Diemert Stephen E Epstein Alun Evans Marco M Ferrario Jean Ferrières Dominique Gauguier Alan S Go Alison H Goodall Villi Gudnason Stanley L Hazen Hilma Holm Carlos Iribarren Yangsoo Jang Mika Kähönen Frank Kee Hyo-Soo Kim Norman Klopp Wolfgang Koenig Wolfgang Kratzer Kari Kuulasmaa Markku Laakso Reijo Laaksonen Ji-Young Lee Lars Lind Willem H Ouwehand Sarah Parish Jeong E Park Nancy L Pedersen Annette Peters Thomas Quertermous Daniel J Rader Veikko Salomaa Eric Schadt Svati H Shah Juha Sinisalo Klaus Stark Kari Stefansson David-Alexandre Trégouët Jarmo Virtamo Lars Wallentin Nicholas Wareham Martina E Zimmermann Markku S Nieminen Christian Hengstenberg Manjinder S Sandhu Tomi Pastinen Ann-Christine Syvänen G Kees Hovingh George Dedoussis Paul W Franks Terho Lehtimäki Andres Metspalu Pierre A Zalloua Agneta Siegbahn Stefan Schreiber Samuli Ripatti Stefan S Blankenberg Markus Perola Robert Clarke Bernhard O Boehm Christopher O'Donnell Muredach P Reilly Winfried März Rory Collins Sekar Kathiresan Anders Hamsten Jaspal S Kooner Unnur Thorsteinsdottir John Danesh Colin N A Palmer Robert Roberts Hugh Watkins Heribert Schunkert Nilesh J Samani

Nat Genet 2013 Jan 2;45(1):25-33. Epub 2012 Dec 2.

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http://dx.doi.org/10.1038/ng.2480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679547PMC
January 2013

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

Authors:
Zari Dastani Marie-France Hivert Nicholas Timpson John R B Perry Xin Yuan Robert A Scott Peter Henneman Iris M Heid Jorge R Kizer Leo-Pekka Lyytikäinen Christian Fuchsberger Toshiko Tanaka Andrew P Morris Kerrin Small Aaron Isaacs Marian Beekman Stefan Coassin Kurt Lohman Lu Qi Stavroula Kanoni James S Pankow Hae-Won Uh Ying Wu Aurelian Bidulescu Laura J Rasmussen-Torvik Celia M T Greenwood Martin Ladouceur Jonna Grimsby Alisa K Manning Ching-Ti Liu Jaspal Kooner Vincent E Mooser Peter Vollenweider Karen A Kapur John Chambers Nicholas J Wareham Claudia Langenberg Rune Frants Ko Willems-Vandijk Ben A Oostra Sara M Willems Claudia Lamina Thomas W Winkler Bruce M Psaty Russell P Tracy Jennifer Brody Ida Chen Jorma Viikari Mika Kähönen Peter P Pramstaller David M Evans Beate St Pourcain Naveed Sattar Andrew R Wood Stefania Bandinelli Olga D Carlson Josephine M Egan Stefan Böhringer Diana van Heemst Lyudmyla Kedenko Kati Kristiansson Marja-Liisa Nuotio Britt-Marie Loo Tamara Harris Melissa Garcia Alka Kanaya Margot Haun Norman Klopp H-Erich Wichmann Panos Deloukas Efi Katsareli David J Couper Bruce B Duncan Margreet Kloppenburg Linda S Adair Judith B Borja James G Wilson Solomon Musani Xiuqing Guo Toby Johnson Robert Semple Tanya M Teslovich Matthew A Allison Susan Redline Sarah G Buxbaum Karen L Mohlke Ingrid Meulenbelt Christie M Ballantyne George V Dedoussis Frank B Hu Yongmei Liu Bernhard Paulweber Timothy D Spector P Eline Slagboom Luigi Ferrucci Antti Jula Markus Perola Olli Raitakari Jose C Florez Veikko Salomaa Johan G Eriksson Timothy M Frayling Andrew A Hicks Terho Lehtimäki George Davey Smith David S Siscovick Florian Kronenberg Cornelia van Duijn Ruth J F Loos Dawn M Waterworth James B Meigs Josee Dupuis J Brent Richards Benjamin F Voight Laura J Scott Valgerdur Steinthorsdottir Christian Dina Ryan P Welch Eleftheria Zeggini Cornelia Huth Yurii S Aulchenko Gudmar Thorleifsson Laura J McCulloch Teresa Ferreira Harald Grallert Najaf Amin Guanming Wu Cristen J Willer Soumya Raychaudhuri Steve A McCarroll Oliver M Hofmann Ayellet V Segrè Mandy van Hoek Pau Navarro Kristin Ardlie Beverley Balkau Rafn Benediktsson Amanda J Bennett Roza Blagieva Eric Boerwinkle Lori L Bonnycastle Kristina Bengtsson Boström Bert Bravenboer Suzannah Bumpstead Noël P Burtt Guillaume Charpentier Peter S Chines Marilyn Cornelis Gabe Crawford Alex S F Doney Katherine S Elliott Amanda L Elliott Michael R Erdos Caroline S Fox Christopher S Franklin Martha Ganser Christian Gieger Niels Grarup Todd Green Simon Griffin Christopher J Groves Candace Guiducci Samy Hadjadj Neelam Hassanali Christian Herder Bo Isomaa Anne U Jackson Paul R V Johnson Torben Jørgensen Wen H L Kao Augustine Kong Peter Kraft Johanna Kuusisto Torsten Lauritzen Man Li Aloysius Lieverse Cecilia M Lindgren Valeriya Lyssenko Michel Marre Thomas Meitinger Kristian Midthjell Mario A Morken Narisu Narisu Peter Nilsson Katharine R Owen Felicity Payne Ann-Kristin Petersen Carl Platou Christine Proença Inga Prokopenko Wolfgang Rathmann N William Rayner Neil R Robertson Ghislain Rocheleau Michael Roden Michael J Sampson Richa Saxena Beverley M Shields Peter Shrader Gunnar Sigurdsson Thomas Sparsø Klaus Strassburger Heather M Stringham Qi Sun Amy J Swift Barbara Thorand Jean Tichet Tiinamaija Tuomi Rob M van Dam Timon W van Haeften Thijs van Herpt Jana V van Vliet-Ostaptchouk G Bragi Walters Michael N Weedon Cisca Wijmenga Jacqueline Witteman Richard N Bergman Stephane Cauchi Francis S Collins Anna L Gloyn Ulf Gyllensten Torben Hansen Winston A Hide Graham A Hitman Albert Hofman David J Hunter Kristian Hveem Markku Laakso Andrew D Morris Colin N A Palmer Igor Rudan Eric Sijbrands Lincoln D Stein Jaakko Tuomilehto Andre Uitterlinden Mark Walker Richard M Watanabe Goncalo R Abecasis Bernhard O Boehm Harry Campbell Mark J Daly Andrew T Hattersley Oluf Pedersen Inês Barroso Leif Groop Rob Sladek Unnur Thorsteinsdottir James F Wilson Thomas Illig Philippe Froguel Cornelia M van Duijn Kari Stefansson David Altshuler Michael Boehnke Mark I McCarthy Nicole Soranzo Eleanor Wheeler Nicole L Glazer Nabila Bouatia-Naji Reedik Mägi Joshua Randall Paul Elliott Denis Rybin Abbas Dehghan Jouke Jan Hottenga Kijoung Song Anuj Goel Taina Lajunen Alex Doney Christine Cavalcanti-Proença Meena Kumari Nicholas J Timpson Carina Zabena Erik Ingelsson Ping An Jeffrey O'Connell Jian'an Luan Amanda Elliott Steven A McCarroll Rosa Maria Roccasecca François Pattou Praveen Sethupathy Yavuz Ariyurek Philip Barter John P Beilby Yoav Ben-Shlomo Sven Bergmann Murielle Bochud Amélie Bonnefond Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Suzannah J Bumpstead Yii-Der Ida Chen Peter Chines Robert Clarke Lachlan J M Coin Matthew N Cooper Laura Crisponi Ian N M Day Eco J C de Geus Jerome Delplanque Annette C Fedson Antje Fischer-Rosinsky Nita G Forouhi Maria Grazia Franzosi Pilar Galan Mark O Goodarzi Jürgen Graessler Scott Grundy Rhian Gwilliam Göran Hallmans Naomi Hammond Xijing Han Anna-Liisa Hartikainen Caroline Hayward Simon C Heath Serge Hercberg David R Hillman Aroon D Hingorani Jennie Hui Joe Hung Marika Kaakinen Jaakko Kaprio Y Antero Kesaniemi Mika Kivimaki Beatrice Knight Seppo Koskinen Peter Kovacs Kirsten Ohm Kyvik G Mark Lathrop Debbie A Lawlor Olivier Le Bacquer Cécile Lecoeur Yun Li Robert Mahley Massimo Mangino María Teresa Martínez-Larrad Jarred B McAteer Ruth McPherson Christa Meisinger David Melzer David Meyre Braxton D Mitchell Sutapa Mukherjee Silvia Naitza Matthew J Neville Marco Orrù Ruth Pakyz Giuseppe Paolisso Cristian Pattaro Daniel Pearson John F Peden Nancy L Pedersen Andreas F H Pfeiffer Irene Pichler Ozren Polasek Danielle Posthuma Simon C Potter Anneli Pouta Michael A Province Nigel W Rayner Kenneth Rice Samuli Ripatti Fernando Rivadeneira Olov Rolandsson Annelli Sandbaek Manjinder Sandhu Serena Sanna Avan Aihie Sayer Paul Scheet Udo Seedorf Stephen J Sharp Beverley Shields Gunnar Sigurðsson Eric J G Sijbrands Angela Silveira Laila Simpson Andrew Singleton Nicholas L Smith Ulla Sovio Amy Swift Holly Syddall Ann-Christine Syvänen Anke Tönjes André G Uitterlinden Ko Willems van Dijk Dhiraj Varma Sophie Visvikis-Siest Veronique Vitart Nicole Vogelzangs Gérard Waeber Peter J Wagner Andrew Walley Kim L Ward Hugh Watkins Sarah H Wild Gonneke Willemsen Jaqueline C M Witteman John W G Yarnell Diana Zelenika Björn Zethelius Guangju Zhai Jing Hua Zhao M Carola Zillikens Ingrid B Borecki Pierre Meneton Patrik K E Magnusson David M Nathan Gordon H Williams Kaisa Silander Stefan R Bornstein Peter Schwarz Joachim Spranger Fredrik Karpe Alan R Shuldiner Cyrus Cooper Manuel Serrano-Ríos Lars Lind Lyle J Palmer Frank B Hu Paul W Franks Shah Ebrahim Michael Marmot W H Linda Kao Peter Paul Pramstaller Alan F Wright Michael Stumvoll Anders Hamsten Thomas A Buchanan Timo T Valle Jerome I Rotter Brenda W J H Penninx Dorret I Boomsma Antonio Cao Angelo Scuteri David Schlessinger Manuela Uda Aimo Ruokonen Marjo-Riitta Jarvelin Leena Peltonen Vincent Mooser Robert Sladek Kiran Musunuru Albert V Smith Andrew C Edmondson Ioannis M Stylianou Masahiro Koseki James P Pirruccello Daniel I Chasman Christopher T Johansen Sigrid W Fouchier Gina M Peloso Maja Barbalic Sally L Ricketts Joshua C Bis Mary F Feitosa Marju Orho-Melander Olle Melander Xiaohui Li Mingyao Li Yoon Shin Cho Min Jin Go Young Jin Kim Jong-Young Lee Taesung Park Kyunga Kim Xueling Sim Rick Twee-Hee Ong Damien C Croteau-Chonka Leslie A Lange Joshua D Smith Andreas Ziegler Weihua Zhang Robert Y L Zee John B Whitfield John R Thompson Ida Surakka Tim D Spector Johannes H Smit Juha Sinisalo James Scott Juha Saharinen Chiara Sabatti Lynda M Rose Robert Roberts Mark Rieder Alex N Parker Guillaume Pare Christopher J O'Donnell Markku S Nieminen Deborah A Nickerson Grant W Montgomery Wendy McArdle David Masson Nicholas G Martin Fabio Marroni Gavin Lucas Robert Luben Marja-Liisa Lokki Guillaume Lettre Lenore J Launer Edward G Lakatta Reijo Laaksonen Kirsten O Kyvik Inke R 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PLoS Genet 2012 29;8(3):e1002607. Epub 2012 Mar 29.

Department of Epidemiology, Biostatistics, and Occupational Health, Jewish General Hospital, Lady Davis Institute, McGill University, Montreal, Canada.

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September 2012

Clinical response to statins: mechanism(s) of variable activity and adverse effects.

Ann Med 2012 Aug 31;44(5):419-32. Epub 2011 May 31.

Dyslipidemia Center, Niguarda Hospital, Milan, Italy.

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http://dx.doi.org/10.3109/07853890.2011.582135DOI Listing
August 2012

miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study.

Atherosclerosis 2011 Nov 22;219(1):211-7. Epub 2011 Jul 22.

Department of Clinical Chemistry, Tampere University Hospital and the Medical School at the University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.07.020DOI Listing
November 2011

A disintegrin and metalloprotease -8 and -15 and susceptibility for ascending aortic dissection.

Scand J Clin Lab Invest 2011 Oct 6;71(6):515-22. Epub 2011 Jul 6.

Department of Clinical Chemistry, Medical School, Tampere University Hospital and Tampere University, Finland.

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http://dx.doi.org/10.3109/00365513.2011.591939DOI Listing
October 2011

The APOE -219G/T and +113G/C polymorphisms affect insulin resistance among Turks.

Metabolism 2011 May 17;60(5):655-63. Epub 2010 Aug 17.

Department of Genetics, Institute for Experimental Medicine, Istanbul University, 34080, Istanbul, Turkey.

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http://dx.doi.org/10.1016/j.metabol.2010.06.016DOI Listing
May 2011

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

Authors:
Heribert Schunkert Inke R König Sekar Kathiresan Muredach P Reilly Themistocles L Assimes Hilma Holm Michael Preuss Alexandre F R Stewart Maja Barbalic Christian Gieger Devin Absher Zouhair Aherrahrou Hooman Allayee David Altshuler Sonia S Anand Karl Andersen Jeffrey L Anderson Diego Ardissino Stephen G Ball Anthony J Balmforth Timothy A Barnes Diane M Becker Lewis C Becker Klaus Berger Joshua C Bis S Matthijs Boekholdt Eric Boerwinkle Peter S Braund Morris J Brown Mary Susan Burnett Ian Buysschaert John F Carlquist Li Chen Sven Cichon Veryan Codd Robert W Davies George Dedoussis Abbas Dehghan Serkalem Demissie Joseph M Devaney Patrick Diemert Ron Do Angela Doering Sandra Eifert Nour Eddine El Mokhtari Stephen G Ellis Roberto Elosua James C Engert Stephen E Epstein Ulf de Faire Marcus Fischer Aaron R Folsom Jennifer Freyer Bruna Gigante Domenico Girelli Solveig Gretarsdottir Vilmundur Gudnason Jeffrey R Gulcher Eran Halperin Naomi Hammond Stanley L Hazen Albert Hofman Benjamin D Horne Thomas Illig Carlos Iribarren Gregory T Jones J Wouter Jukema Michael A Kaiser Lee M Kaplan John J P Kastelein Kay-Tee Khaw Joshua W Knowles Genovefa Kolovou Augustine Kong Reijo Laaksonen Diether Lambrechts Karin Leander Guillaume Lettre Mingyao Li Wolfgang Lieb Christina Loley Andrew J Lotery Pier M Mannucci Seraya Maouche Nicola Martinelli Pascal P McKeown Christa Meisinger Thomas Meitinger Olle Melander Pier Angelica Merlini Vincent Mooser Thomas Morgan Thomas W Mühleisen Joseph B Muhlestein Thomas Münzel Kiran Musunuru Janja Nahrstaedt Christopher P Nelson Markus M Nöthen Oliviero Olivieri Riyaz S Patel Chris C Patterson Annette Peters Flora Peyvandi Liming Qu Arshed A Quyyumi Daniel J Rader Loukianos S Rallidis Catherine Rice Frits R Rosendaal Diana Rubin Veikko Salomaa M Lourdes Sampietro Manj S Sandhu Eric Schadt Arne Schäfer Arne Schillert Stefan Schreiber Jürgen Schrezenmeir Stephen M Schwartz David S Siscovick Mohan Sivananthan Suthesh Sivapalaratnam Albert Smith Tamara B Smith Jaapjan D Snoep Nicole Soranzo John A Spertus Klaus Stark Kathy Stirrups Monika Stoll W H Wilson Tang Stephanie Tennstedt Gudmundur Thorgeirsson Gudmar Thorleifsson Maciej Tomaszewski Andre G Uitterlinden Andre M van Rij Benjamin F Voight Nick J Wareham George A Wells H-Erich Wichmann Philipp S Wild Christina Willenborg Jaqueline C M Witteman Benjamin J Wright Shu Ye Tanja Zeller Andreas Ziegler Francois Cambien Alison H Goodall L Adrienne Cupples Thomas Quertermous Winfried März Christian Hengstenberg Stefan Blankenberg Willem H Ouwehand Alistair S Hall Panos Deloukas John R Thompson Kari Stefansson Robert Roberts Unnur Thorsteinsdottir Christopher J O'Donnell Ruth McPherson Jeanette Erdmann Nilesh J Samani

Nat Genet 2011 Mar 6;43(4):333-8. Epub 2011 Mar 6.

Universität zu Lübeck, Medizinische Klinik II, Lübeck, Germany.

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http://dx.doi.org/10.1038/ng.784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119261PMC
March 2011

Niemann-Pick type C fibroblasts have a distinct microRNA profile related to lipid metabolism and certain cellular components.

Biochem Biophys Res Commun 2010 Dec 12;403(3-4):316-21. Epub 2010 Nov 12.

Department of Clinical Chemistry, Tampere University Hospital and University of Tampere, Finland.

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http://dx.doi.org/10.1016/j.bbrc.2010.11.026DOI Listing
December 2010

Biological, clinical and population relevance of 95 loci for blood lipids.

Authors:
Tanya M Teslovich Kiran Musunuru Albert V Smith Andrew C Edmondson Ioannis M Stylianou Masahiro Koseki James P Pirruccello Samuli Ripatti Daniel I Chasman Cristen J Willer Christopher T Johansen Sigrid W Fouchier Aaron Isaacs Gina M Peloso Maja Barbalic Sally L Ricketts Joshua C Bis Yurii S Aulchenko Gudmar Thorleifsson Mary F Feitosa John Chambers Marju Orho-Melander Olle Melander Toby Johnson Xiaohui Li Xiuqing Guo Mingyao Li Yoon Shin Cho Min Jin Go Young Jin Kim Jong-Young Lee Taesung Park Kyunga Kim Xueling Sim Rick Twee-Hee Ong Damien C Croteau-Chonka Leslie A Lange Joshua D Smith Kijoung Song Jing Hua Zhao Xin Yuan Jian'an Luan Claudia Lamina Andreas Ziegler Weihua Zhang Robert Y L Zee Alan F Wright Jacqueline C M Witteman James F Wilson Gonneke Willemsen H-Erich Wichmann John B Whitfield Dawn M Waterworth Nicholas J Wareham Gérard Waeber Peter Vollenweider Benjamin F Voight Veronique Vitart Andre G Uitterlinden Manuela Uda Jaakko Tuomilehto John R Thompson Toshiko Tanaka Ida Surakka Heather M Stringham Tim D Spector Nicole Soranzo Johannes H Smit Juha Sinisalo Kaisa Silander Eric J G Sijbrands Angelo Scuteri James Scott David Schlessinger Serena Sanna Veikko Salomaa Juha Saharinen Chiara Sabatti Aimo Ruokonen Igor Rudan Lynda M Rose Robert Roberts Mark Rieder Bruce M Psaty Peter P Pramstaller Irene Pichler Markus Perola Brenda W J H Penninx Nancy L Pedersen Cristian Pattaro Alex N Parker Guillaume Pare Ben A Oostra Christopher J O'Donnell Markku S Nieminen Deborah A Nickerson Grant W Montgomery Thomas Meitinger Ruth McPherson Mark I McCarthy Wendy McArdle David Masson Nicholas G Martin Fabio Marroni Massimo Mangino Patrik K E Magnusson Gavin Lucas Robert Luben Ruth J F Loos Marja-Liisa Lokki Guillaume Lettre Claudia Langenberg Lenore J Launer Edward G Lakatta Reijo Laaksonen Kirsten O Kyvik Florian Kronenberg Inke R König Kay-Tee Khaw Jaakko Kaprio Lee M Kaplan Asa Johansson Marjo-Riitta Jarvelin A Cecile J W Janssens Erik Ingelsson Wilmar Igl G Kees Hovingh Jouke-Jan Hottenga Albert Hofman Andrew A Hicks Christian Hengstenberg Iris M Heid Caroline Hayward Aki S Havulinna Nicholas D Hastie Tamara B Harris Talin Haritunians Alistair S Hall Ulf Gyllensten Candace Guiducci Leif C Groop Elena Gonzalez Christian Gieger Nelson B Freimer Luigi Ferrucci Jeanette Erdmann Paul Elliott Kenechi G Ejebe Angela Döring Anna F Dominiczak Serkalem Demissie Panagiotis Deloukas Eco J C de Geus Ulf de Faire Gabriel Crawford Francis S Collins Yii-der I Chen Mark J Caulfield Harry Campbell Noel P Burtt Lori L Bonnycastle Dorret I Boomsma S Matthijs Boekholdt Richard N Bergman Inês Barroso Stefania Bandinelli Christie M Ballantyne Themistocles L Assimes Thomas Quertermous David Altshuler Mark Seielstad Tien Y Wong E-Shyong Tai Alan B Feranil Christopher W Kuzawa Linda S Adair Herman A Taylor Ingrid B Borecki Stacey B Gabriel James G Wilson Hilma Holm Unnur Thorsteinsdottir Vilmundur Gudnason Ronald M Krauss Karen L Mohlke Jose M Ordovas Patricia B Munroe Jaspal S Kooner Alan R Tall Robert A Hegele John J P Kastelein Eric E Schadt Jerome I Rotter Eric Boerwinkle David P Strachan Vincent Mooser Kari Stefansson Muredach P Reilly Nilesh J Samani Heribert Schunkert L Adrienne Cupples Manjinder S Sandhu Paul M Ridker Daniel J Rader Cornelia M van Duijn Leena Peltonen Gonçalo R Abecasis Michael Boehnke Sekar Kathiresan

Nature 2010 Aug;466(7307):707-13

Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1038/nature09270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039276PMC
August 2010

Lipidomics: a tool for studies of atherosclerosis.

Curr Atheroscler Rep 2010 Jul;12(4):273-81

Zora Biosciences Oy, Espoo, Finland.

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http://dx.doi.org/10.1007/s11883-010-0110-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878593PMC
July 2010

Carbonic anhydrases II and XII are up-regulated in osteoclast-like cells in advanced human atherosclerotic plaques-Tampere Vascular Study.

Ann Med 2010 Jul;42(5):360-70

Centre for Laboratory Medicine, Tampere University Hospital and Department of Clinical Chemistry, Medical School, University of Tampere, Tampere, Finland.

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http://dx.doi.org/10.3109/07853890.2010.486408DOI Listing
July 2010

Activation of indoleamine 2,3-dioxygenase-induced tryptophan degradation in advanced atherosclerotic plaques: Tampere vascular study.

Ann Med 2010 ;42(1):55-63

Department of Clinical Chemistry, University of Tampere, Medical School, and Tampere University Hospital, Centre for Laboratory Medicine, Tampere, Finland.

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http://dx.doi.org/10.3109/07853890903321559DOI Listing
March 2010

ADMA concentration changes across the menstrual cycle and during oral contraceptive use: the Cardiovascular Risk in Young Finns Study.

Eur J Endocrinol 2010 Feb 24;162(2):259-65. Epub 2009 Nov 24.

Departments of Clinical Chemistry Obstetrics and Gynaecology, Kuopio University Hospital and University of Kuopio, FIN-70210 Kuopio, Finland.

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http://dx.doi.org/10.1530/EJE-09-0658DOI Listing
February 2010

Lipidomics-based safety biomarkers for lipid-lowering treatments.

Angiology 2008 Apr-May;59(2 Suppl):65S-8S. Epub 2008 Jul 16.

Science Center, Tampere University Hospital, Zora Biosciences Oy, Espoo, Finland.

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http://journals.sagepub.com/doi/10.1177/0003319708321106
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October 2008

Metabolomic strategies to identify tissue-specific effects of cardiovascular drugs.

Expert Opin Drug Metab Toxicol 2008 Jun;4(6):665-80

Zora Biosciences Oy, Biologinkuja 1, Espoo, FI-02150, Finland.

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http://dx.doi.org/10.1517/17425255.4.6.665 DOI Listing
June 2008

Transport properties of bovine and reindeer beta-lactoglobulin in the Caco-2 cell model.

Int J Pharm 2008 Jan 19;347(1-2):1-8. Epub 2007 Jun 19.

Drug Discovery and Development Technology Center, Faculty of Pharmacy, University of Helsinki, P.O. Box 56, FI-00014 Helsinki, Finland.

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http://dx.doi.org/10.1016/j.ijpharm.2007.06.015DOI Listing
January 2008

Coronary reactivity, homocysteine and methylenetetrahydrofolate reductase gene variation in young men during pravastatin therapy.

Vascul Pharmacol 2007 Aug-Sep;47(2-3):113-7. Epub 2007 May 13.

Department of Pharmacological Sciences, Medical School, FI-33014 University of Tampere, Finland.

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http://dx.doi.org/10.1016/j.vph.2007.05.001DOI Listing
December 2007

Plasma asymmetric dimethylarginine and retinal vessel diameters in middle-aged men.

Metabolism 2007 Oct;56(10):1305-10

Department of Clinical Physiology, Medical School, University of Tampere, 33014 Tampere, Finland.

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http://dx.doi.org/10.1016/j.metabol.2007.05.012DOI Listing
October 2007

Gene set enrichment analyses revealed several affected pathways in Niemann-pick disease type C fibroblasts.

DNA Cell Biol 2007 Sep;26(9):665-71

Department of Neurology and Laboratory of Experimental Neurology, ULB Erasme Hospital, Brussels, Belgium, and Turku Centre for Biotechnology, University of Turku, Finland.

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http://dx.doi.org/10.1089/dna.2006.0570DOI Listing
September 2007

Osteopontin levels are associated with cholesterol synthesis markers in mildly hypercholesterolaemic patients.

Acta Cardiol 2007 Apr;62(2):177-81

Laboratory of Atherosclerosis Genetics, Centre for Laboratory Medicine, Tampere University Hospital, Finn-Medi 5 7th floor, P.O. Box 2000, 33521, Tampere, Finland.

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http://dx.doi.org/10.2143/AC.62.2.2020239DOI Listing
April 2007

The influence of hepatic lipase C-480T polymorphism on coronary flow reserve in young men is independent of the plasma cholesterol level.

Atherosclerosis 2006 Oct 2;188(2):391-7. Epub 2005 Dec 2.

Laboratory of Atherosclerosis Genetics, Centre for Laboratory Medicine, Tampere University Hospital and University of Tampere, Medical School, Department of Clinical Chemistry, Finn-Medi 2, 3rd Floor, P.O. Box 2000, FIN-33521 Tampere, Finland.

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http://dx.doi.org/10.1016/j.atherosclerosis.2005.11.003DOI Listing
October 2006

Plasma-soluble CD40 is related to cholesterol metabolism in patients with moderate hypercholesterolemia.

Scand Cardiovasc J 2006 Oct;40(5):280-4

Laboratory of Atherosclerosis Genetics, Centre for Laboratory Medicine, Department of Clinical Chemistry, Tampere and Medical School, Tampere University HospitalUniversity of Tampere, P.O. Box 2000, FI-33521, Finland.

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http://www.tandfonline.com/doi/full/10.1080/1401743060095997
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http://dx.doi.org/10.1080/14017430600959978DOI Listing
October 2006

Plasma asymmetric dimethylarginine (ADMA), nitrate and the indices of low-density lipoprotein oxidation.

Clin Chim Acta 2006 Sep 2;371(1-2):97-101. Epub 2006 Mar 2.

Department of Internal Medicine, University Hospital of Tampere, Tampere, Finland.

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http://dx.doi.org/10.1016/j.cca.2006.02.028DOI Listing
September 2006

High-dose statin treatment does not alter plasma marker for brain cholesterol metabolism in patients with moderately elevated plasma cholesterol levels.

J Clin Pharmacol 2006 Jul;46(7):812-6

Department of Clinical Pharmacology, University of Bonn, Sigmund-Freud-Str. 25, D-53105 Bonn, Germany.

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http://dx.doi.org/10.1177/0091270006289851DOI Listing
July 2006

Asymmetric dimethylarginine and hemodynamic regulation in middle-aged men.

Metabolism 2006 Jun;55(6):771-7

Department of Internal Medicine, Tampere University Hospital, 33521 Tampere, Finland.

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http://dx.doi.org/10.1016/j.metabol.2006.01.014DOI Listing
June 2006

On the mechanisms of statin-induced myopathy.

Authors:
Reijo Laaksonen

Clin Pharmacol Ther 2006 Jun 2;79(6):529-31. Epub 2006 May 2.

Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1016/j.clpt.2006.02.013DOI Listing
June 2006

Effect of pravastatin on plasma sterols and oxysterols in men.

Eur J Clin Pharmacol 2006 Jan 30;62(1):9-14. Epub 2005 Dec 30.

Department of Clinical Pharmacology, University of Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Germany, and Laboratory of Atherosclerosis Genetics, Department of Clinical Chemistry, University Hospital of Tampere, Finland.

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http://dx.doi.org/10.1007/s00228-005-0068-9DOI Listing
January 2006

DDAH gene and cardiovascular risk.

Vasc Med 2005 Jul;10 Suppl 1:S45-8

The Research Institute of Public Health, University of Kuopio, Finland.

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http://dx.doi.org/10.1191/1358863x05vm600oaDOI Listing
July 2005