Ramnik Xavier

Ramnik Xavier

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Comprehensive analysis of chromosomal mobile genetic elements in the gut microbiome reveals phylum-level niche-adaptive gene pools.

PLoS One 2019 12;14(12):e0223680. Epub 2019 Dec 12.

Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0223680PLOS
December 2019

Distinct Tissue-Specific Roles for the Disease-Associated Autophagy Genes ATG16L2 and ATG16L1.

J Immunol 2019 Oct 26;203(7):1820-1829. Epub 2019 Aug 26.

Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114;

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http://dx.doi.org/10.4049/jimmunol.1800419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761021PMC
October 2019

Calcitonin Gene-Related Peptide Negatively Regulates Alarmin-Driven Type 2 Innate Lymphoid Cell Responses.

Immunity 2019 Oct 8;51(4):709-723.e6. Epub 2019 Oct 8.

Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.09.005DOI Listing
October 2019

Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses.

Immunity 2019 Oct;51(4):696-708.e9

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02114, USA; Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613193037
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http://dx.doi.org/10.1016/j.immuni.2019.09.004DOI Listing
October 2019

Targeting innate immunity for tuberculosis vaccination.

J Clin Invest 2019 Sep;129(9):3482-3491

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, Netherlands.

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http://dx.doi.org/10.1172/JCI128877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715374PMC
September 2019

Gene networks that compensate for crosstalk with crosstalk.

Nat Commun 2019 09 6;10(1):4028. Epub 2019 Sep 6.

Synthetic Biology Group, MIT Synthetic Biology Center, Research Laboratory of Electronics, Department of Electrical Engineering & Computer Science, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.

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http://dx.doi.org/10.1038/s41467-019-12021-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731275PMC
September 2019

Microbial genes and pathways in inflammatory bowel disease.

Nat Rev Microbiol 2019 Aug;17(8):497-511

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41579-019-0213-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759048PMC
August 2019

Therapeutic Opportunities in Inflammatory Bowel Disease: Mechanistic Dissection of Host-Microbiome Relationships.

Cell 2019 Aug;178(5):1041-1056

Broad Institute of MIT and Harvard, Cambridge, MA, USA; Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Department of Molecular Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Center for Microbiome Informatics and Therapeutics, MIT, Cambridge, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.07.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778965PMC
August 2019

Induction of the metal transporter ZIP8 by interferon gamma in intestinal epithelial cells: Potential role of metal dyshomeostasis in Crohn's disease.

Biochem Biophys Res Commun 2019 Jul 29;515(2):325-331. Epub 2019 May 29.

Department of Medicine, Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.

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http://dx.doi.org/10.1016/j.bbrc.2019.05.137DOI Listing
July 2019

, a member of the human gut microbiome associated with Crohn's disease, produces an inflammatory polysaccharide.

Proc Natl Acad Sci U S A 2019 Jun 10;116(26):12672-12677. Epub 2019 Jun 10.

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston MA 02115;

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http://dx.doi.org/10.1073/pnas.1904099116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601261PMC
June 2019

induces intestinal adaptive immune responses during homeostasis.

Science 2019 06;364(6446):1179-1184

Division of Immunology and Pathogenesis, Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.

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http://dx.doi.org/10.1126/science.aaw7479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645389PMC
June 2019

Adaptive Evolution within Gut Microbiomes of Healthy People.

Cell Host Microbe 2019 05 23;25(5):656-667.e8. Epub 2019 Apr 23.

Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19313128193015
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http://dx.doi.org/10.1016/j.chom.2019.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749991PMC
May 2019

Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice.

PLoS Genet 2019 05 6;15(5):e1008084. Epub 2019 May 6.

Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, KS, United States of America.

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http://dx.plos.org/10.1371/journal.pgen.1008084
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http://dx.doi.org/10.1371/journal.pgen.1008084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502318PMC
May 2019

Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis.

Cell Host Microbe 2019 05;25(5):668-680.e7

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Center for Computational and Integrative Biology and Department of Molecular Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19313128193020
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http://dx.doi.org/10.1016/j.chom.2019.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544385PMC
May 2019

Gut Microbiota Regulation of T Cells During Inflammation and Autoimmunity.

Annu Rev Immunol 2019 Apr;37:599-624

Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA; email: ,

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http://dx.doi.org/10.1146/annurev-immunol-042718-041841DOI Listing
April 2019

Mechanisms and function of autophagy in intestinal disease.

Autophagy 2018 29;14(2):216-220. Epub 2018 Jan 29.

a Broad Institute ; Cambridge , MA USA.

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https://www.tandfonline.com/doi/full/10.1080/15548627.2017.1
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http://dx.doi.org/10.1080/15548627.2017.1389358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902220PMC
February 2019

Single-Cell RNA Sequencing of Blood and Ileal T Cells From Patients With Crohn's Disease Reveals Tissue-Specific Characteristics and Drug Targets.

Gastroenterology 2019 02 2;156(3):812-815.e22. Epub 2018 Nov 2.

Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2018.10.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759855PMC
February 2019

Spatial and Temporal Mapping of Human Innate Lymphoid Cells Reveals Elements of Tissue Specificity.

Immunity 2019 02 12;50(2):505-519.e4. Epub 2019 Feb 12.

Jill Roberts Institute for Research in Inflammatory Bowel Disease, Joan and Stanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, 10021, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594374PMC
February 2019

Impaired Aryl Hydrocarbon Receptor Ligand Production by the Gut Microbiota Is a Key Factor in Metabolic Syndrome.

Cell Metab 2018 11 26;28(5):737-749.e4. Epub 2018 Jul 26.

Micalis Institute, Institut National de la Recherche Agronomique (INRA), AgroParisTech, Université Paris-Saclay, 78352 Jouy-en-Josas, France; Sorbonne Universités, UPMC Univ. Paris 06, École Normale Supérieure, CNRS, INSERM, APHP Laboratoire des Biomolécules (LBM), 27 rue de Chaligny, 75012 Paris, France; Department of Gastroenterology, Saint Antoine Hospital, Assistance Publique - Hopitaux de Paris, UPMC, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.07.001DOI Listing
November 2018

Multiomics Analyses to Deliver the Most Effective Treatment to Every Patient With Inflammatory Bowel Disease.

Gastroenterology 2018 11 2;155(5):e1-e4. Epub 2018 Aug 2.

Genomics plc, Oxford, United Kingdom.

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http://dx.doi.org/10.1053/j.gastro.2018.07.039DOI Listing
November 2018

T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation.

Cell 2018 11 1;175(5):1307-1320.e22. Epub 2018 Nov 1.

Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, MA 02114, USA; Center for Microbiome informatics and Therapeutics, MIT, Cambridge, MA 02139, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183131
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http://dx.doi.org/10.1016/j.cell.2018.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239889PMC
November 2018

The causes and consequences of variation in human cytokine production in health.

Curr Opin Immunol 2018 10 15;54:50-58. Epub 2018 Jun 15.

The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, MA 02114, USA; Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2018.05.012DOI Listing
October 2018

Salt-Inducible Kinases: Physiology, Regulation by cAMP, and Therapeutic Potential.

Trends Endocrinol Metab 2018 10 24;29(10):723-735. Epub 2018 Aug 24.

Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.tem.2018.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151151PMC
October 2018

Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course.

Cell Host Microbe 2018 10;24(4):600-610.e4

The Broad Institute of MIT and Harvard, Infectious Disease and Microbiome, Cambridge, MA 02142, USA; Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, MA 02114, USA; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277984PMC
October 2018

Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2.

Proc Natl Acad Sci U S A 2018 09 20;115(36):E8460-E8468. Epub 2018 Aug 20.

Department of Molecular and Cellular Therapeutics, Tissue Engineering Regenerative Group, Royal College of Surgeons in Ireland, Dublin 2, Ireland;

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http://dx.doi.org/10.1073/pnas.1800431115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130388PMC
September 2018

Genetic Markers Predict Primary Nonresponse and Durable Response to Anti-Tumor Necrosis Factor Therapy in Ulcerative Colitis.

Inflamm Bowel Dis 2018 07;24(8):1840-1848

Inflammatory Bowel Disease Center, Division of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1093/ibd/izy083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128143PMC
July 2018

Strain-Level Analysis of Mother-to-Child Bacterial Transmission during the First Few Months of Life.

Cell Host Microbe 2018 07;24(1):146-154.e4

The Broad Institute of MIT and Harvard, Cambridge, MA 02138, USA; Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02138, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091882PMC
July 2018

Nitric Oxide Engages an Anti-inflammatory Feedback Loop Mediated by Peroxiredoxin 5 in Phagocytes.

Cell Rep 2018 07;24(4):838-850

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School, Boston, MA 02114, USA; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.06.081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156773PMC
July 2018

The classroom microbiome and asthma morbidity in children attending 3 inner-city schools.

J Allergy Clin Immunol 2018 06 5;141(6):2311-2313. Epub 2018 Mar 5.

Harvard Medical School, Boston, Mass; Broad Institute of MIT and Harvard University, Cambridge, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.02.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994187PMC
June 2018

A Common Mechanism Links Activities of Butyrate in the Colon.

ACS Chem Biol 2018 05 10;13(5):1291-1298. Epub 2018 Apr 10.

Department of Chemistry and Chemical Biology , Harvard University , Cambridge , Massachusetts 02138 , United States.

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http://pubs.acs.org/doi/10.1021/acschembio.8b00073
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http://dx.doi.org/10.1021/acschembio.8b00073DOI Listing
May 2018

Obesity, but Not Physical Activity, Is Associated With Higher Prevalence of Asymptomatic Diverticulosis.

Clin Gastroenterol Hepatol 2018 04 9;16(4):586-587. Epub 2017 Sep 9.

Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Clinical and Translational Epidemiology Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Clinical Epidemiology Unit, Karolinska Institutet, Solna, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2017.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844811PMC
April 2018

Without Adaptive Immunity, There's a Cost to Responding STAT.

Cell Metab 2018 04;27(4):705-707

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.03.011DOI Listing
April 2018

Loss of Response to Anti-Tumor Necrosis Factor Alpha Therapy in Crohn's Disease Is Not Associated with Emergence of Novel Inflammatory Pathways.

Dig Dis Sci 2018 03 25;63(3):738-745. Epub 2018 Jan 25.

Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Blake 4, 55 Fruit Street, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1007/s10620-018-4932-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152907PMC
March 2018

Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation.

Cell Host Microbe 2018 Feb;23(2):229-240.e5

Broad Institute of MIT and Harvard, Cambridge, MA, USA; The Center for Microbiome Informatics and Therapeutics, MIT, Cambridge, MA, USA; Finch Therapeutics, Somerville, MA, USA; Department of Biological Engineering, MIT, Cambridge, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.01.003DOI Listing
February 2018

BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity.

Cell Host Microbe 2018 Jan;23(1):89-100.e5

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2017.12.010DOI Listing
January 2018

Host genetic variation and its microbiome interactions within the Human Microbiome Project.

Genome Med 2018 01 29;10(1). Epub 2018 Jan 29.

Department of Biostatistics, Harvard T. H. Chan School of Public Health, 655 Huntington Ave, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1186/s13073-018-0515-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789541PMC
January 2018

Human genetic variation and the gut microbiome in disease.

Nat Rev Genet 2017 11 21;18(11):690-699. Epub 2017 Aug 21.

Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nrg.2017.63DOI Listing
November 2017

SHANK3 Regulates Intestinal Barrier Function Through Modulating ZO-1 Expression Through the PKCε-dependent Pathway.

Inflamm Bowel Dis 2017 10;23(10):1730-1740

*Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan; †Institutes of Molecular Biology, Academia Sinica, Taipei, Taiwan; ‡Department of Pediatrics, College of Medicine, National Taiwan University, Taipei, Taiwan; §Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei, Taiwan; ‖Department of Integrated Diagnostics and Therapeutics, College of Medicine, National Taiwan University, Taipei, Taiwan; ¶Graduate Institute of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan; **Bioinformatics and Biostatistics Core, Center of Genomic Medicine, National Taiwan University, Taipei, Taiwan; ††Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan; ‡‡Department of Pathology and Forensic Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan; §§Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, Massachusetts; ‖‖UT Southwestern Medical Center, Dallas, Texas; and ¶¶Institutes of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.

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http://dx.doi.org/10.1097/MIB.0000000000001250DOI Listing
October 2017

p40 -Deficient Mice Exhibit Impaired Bacterial Clearance and Enhanced Pro-inflammatory Responses during serovar Typhimurium Infection.

Front Immunol 2017 9;8:1270. Epub 2017 Oct 9.

Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.

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http://dx.doi.org/10.3389/fimmu.2017.01270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640886PMC
October 2017

Transcription factor TFEB cell-autonomously modulates susceptibility to intestinal epithelial cell injury in vivo.

Sci Rep 2017 10 24;7(1):13938. Epub 2017 Oct 24.

Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1038/s41598-017-14370-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655326PMC
October 2017

Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine.

Science 2017 09 27;357(6355):1047-1052. Epub 2017 Jul 27.

Department of Immunology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1126/science.aal4677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702267PMC
September 2017

Indoleacrylic Acid Produced by Commensal Peptostreptococcus Species Suppresses Inflammation.

Cell Host Microbe 2017 Jul;22(1):25-37.e6

The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2017.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672633PMC
July 2017