Rajiv Chopra

Rajiv Chopra

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Rajiv Chopra

Publications by authors named "Rajiv Chopra"

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Influence of Nanobubble Concentration on Blood-Brain Barrier Opening Using Focused Ultrasound Under Real-Time Acoustic Feedback Control.

Ultrasound Med Biol 2019 08 7;45(8):2174-2187. Epub 2019 May 7.

Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA; Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1016/j.ultrasmedbio.2019.03.016DOI Listing
August 2019

Cam-type femoroacetabular impingement-correlations between alpha angle versus volumetric measurements and surgical findings.

Eur Radiol 2019 Jul 11;29(7):3431-3440. Epub 2019 Feb 11.

Department of Orthopedic Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1007/s00330-018-5968-zDOI Listing
July 2019

Prototype volumetric ultrasound tomography image guidance system for prone stereotactic partial breast irradiation: proof-of-concept.

Phys Med Biol 2018 03 1;63(5):055004. Epub 2018 Mar 1.

Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America. Tsuicheng Chiu and David Parsons contributed equally to this study.

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http://dx.doi.org/10.1088/1361-6560/aaad1fDOI Listing
March 2018

Introduction to the special issue on thermal therapy and infectious diseases.

Int J Hyperthermia 2018 03;34(2):133-134

d Microbiology and Immunology , University of Arkansas for Medical Sciences , Little Rock , AR , USA.

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http://dx.doi.org/10.1080/02656736.2018.1424947DOI Listing
March 2018

Development of a Patient-specific Tumor Mold Using Magnetic Resonance Imaging and 3-Dimensional Printing Technology for Targeted Tissue Procurement and Radiomics Analysis of Renal Masses.

Urology 2018 Feb 19;112:209-214. Epub 2017 Oct 19.

Department of Radiology, UT Southwestern Medical Center, Dallas, TX; Department of Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX; Department of Urology, UT Southwestern Medical Center, Dallas, TX. Electronic address:

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http://dx.doi.org/10.1016/j.urology.2017.08.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885749PMC
February 2018

Technical Note: System for evaluating local hypothermia as a radioprotector of the rectum in a small animal model.

Med Phys 2017 Aug 16;44(8):3932-3938. Epub 2017 Jun 16.

Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1002/mp.12353DOI Listing
August 2017

Local Hypothermia as a Radioprotector of the Rectal Wall During Prostate Stereotactic Body Radiation Therapy.

Int J Radiat Oncol Biol Phys 2017 05 11;98(1):75-82. Epub 2017 Jan 11.

Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1016/j.ijrobp.2017.01.017DOI Listing
May 2017

Localised hyperthermia in rodent models using an MRI-compatible high-intensity focused ultrasound system.

Int J Hyperthermia 2015 5;31(8):813-22. Epub 2015 Nov 5.

a Department of Radiology , University of Texas Southwestern Medical Center , Dallas , Texas .

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http://dx.doi.org/10.3109/02656736.2015.1094833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701604PMC
October 2016

Pediatric Sarcomas Are Targetable by MR-Guided High Intensity Focused Ultrasound (MR-HIFU): Anatomical Distribution and Radiological Characteristics.

Pediatr Blood Cancer 2016 10 19;63(10):1753-60. Epub 2016 May 19.

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1002/pbc.26079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016837PMC
October 2016

Three-dimensional printing for preoperative planning of total hip arthroplasty revision: case report.

Skeletal Radiol 2016 Oct 1;45(10):1431-5. Epub 2016 Aug 1.

Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-9178, USA.

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http://dx.doi.org/10.1007/s00256-016-2444-1DOI Listing
October 2016

Drift correction for accurate PRF-shift MR thermometry during mild hyperthermia treatments with MR-HIFU.

Int J Hyperthermia 2016 09 22;32(6):673-87. Epub 2016 May 22.

a Department of Radiology , University of Texas Southwestern Medical Center , Dallas , Texas , USA ;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045807PMC
http://dx.doi.org/10.1080/02656736.2016.1179799DOI Listing
September 2016

An MRI-compatible platform for one-dimensional motion management studies in MRI.

Magn Reson Med 2016 08 23;76(2):702-12. Epub 2015 Oct 23.

Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1002/mrm.25903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342555PMC
August 2016

Characterizing spatiotemporal information loss in sparse-sampling-based dynamic MRI for monitoring respiration-induced tumor motion in radiotherapy.

Med Phys 2016 Jun;43(6):2807-2820

Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, Texas 75390; Department of Radiology, UT Southwestern Medical Center, Dallas, Texas 75390; and Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland, 21201.

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http://dx.doi.org/10.1118/1.4948684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866962PMC
June 2016

Structural and Functional Consequences of Three Cancer-Associated Mutations of the Oncogenic Phosphatase SHP2.

Biochemistry 2016 Apr 11;55(15):2269-77. Epub 2016 Apr 11.

Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School , Boston, Massachusetts 02115, United States.

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http://dx.doi.org/10.1021/acs.biochem.5b01287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900891PMC
April 2016

Localized delivery of low-density lipoprotein docosahexaenoic acid nanoparticles to the rat brain using focused ultrasound.

Biomaterials 2016 Mar 6;83:257-68. Epub 2016 Jan 6.

Advanced Imaging Research Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA; Internal Medicine, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.01.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754139PMC
March 2016

Influence of geometric and material properties on artifacts generated by interventional MRI devices: Relevance to PRF-shift thermometry.

Med Phys 2016 Jan;43(1):241

Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390; Advanced Imaging Research Center, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390; Physical Sciences, Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, Ontario M4N3M5, Canada; and Department of Medical Biophysics, University of Toronto, 610 University Avenue, Toronto, Ontario M5G2M9, Canada.

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http://dx.doi.org/10.1118/1.4938099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691251PMC
January 2016

MRI-controlled ultrasound thermal therapy.

IEEE Pulse 2011 Sep-Oct;2(5):39-47

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http://dx.doi.org/10.1109/MPUL.2011.942604DOI Listing
October 2015

Impact of the N-Terminal Domain of STAT3 in STAT3-Dependent Transcriptional Activity.

Mol Cell Biol 2015 Oct 13;35(19):3284-300. Epub 2015 Jul 13.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA Biophysical Collaborative Access Team/Illinois Institute of Technology, Sector 18ID (Advanced Photon Source, Argonne National Laboratory), Lemont, Illinois, USA Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA

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http://dx.doi.org/10.1128/MCB.00060-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561728PMC
October 2015

Insights into Autoregulation of Notch3 from Structural and Functional Studies of Its Negative Regulatory Region.

Structure 2015 Jul 4;23(7):1227-35. Epub 2015 Jun 4.

Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2015.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497832PMC
July 2015

Hyperthermia-mediated doxorubicin release from thermosensitive liposomes using MR-HIFU: therapeutic effect in rabbit Vx2 tumours.

Int J Hyperthermia 2015 Mar 13;31(2):118-33. Epub 2015 Jan 13.

Physical Sciences Platform, Sunnybrook Research Institute , Toronto, Ontario , Canada .

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http://dx.doi.org/10.3109/02656736.2014.992483DOI Listing
March 2015

Thermometry and ablation monitoring with ultrasound.

Int J Hyperthermia 2015 Mar 10;31(2):163-81. Epub 2015 Mar 10.

Department of Radiology, University of Texas Southwestern Medical Center , Dallas, Texas , USA .

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http://dx.doi.org/10.3109/02656736.2015.1009180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467963PMC
March 2015

Development of robust/predictive control strategies for image-guided ablative treatments using a minimally invasive ultrasound applicator.

Int J Hyperthermia 2014 Nov 14;30(7):438-46. Epub 2014 Oct 14.

Department of Electrical and Computer Engineering, University of Toronto , Toronto , Canada .

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http://dx.doi.org/10.3109/02656736.2014.963702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437629PMC
November 2014

Spatiotemporal filtering of MR-temperature artifacts arising from bowel motion during transurethral MR-HIFU.

Med Phys 2014 Nov;41(11):113302

Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canadaand Department of Radiology, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9061.

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http://dx.doi.org/10.1118/1.4897382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290727PMC
November 2014

Trans-cranial opening of the blood-brain barrier in targeted regions using a stereotaxic brain atlas and focused ultrasound energy.

J Ther Ultrasound 2014 4;2:13. Epub 2014 Aug 4.

Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9061, USA.

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http://dx.doi.org/10.1186/2050-5736-2-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160001PMC
September 2014

Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors.

Bioorg Med Chem Lett 2014 Aug 20;24(16):3979-85. Epub 2014 Jun 20.

Global Discovery Chemistry, Novartis Institutes for BioMedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X140065
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http://dx.doi.org/10.1016/j.bmcl.2014.06.031DOI Listing
August 2014

MR thermometry in the human prostate gland at 3.0T for transurethral ultrasound therapy.

J Magn Reson Imaging 2013 Dec 25;38(6):1564-71. Epub 2013 Feb 25.

Physical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/jmri.24063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193924PMC
December 2013

Incorporating endorectal MR elastography into multi-parametric MRI for prostate cancer imaging: Initial feasibility in volunteers.

J Magn Reson Imaging 2013 Nov 13;38(5):1251-60. Epub 2013 Feb 13.

Physical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/jmri.24028DOI Listing
November 2013

Enhanced drug delivery in rabbit VX2 tumours using thermosensitive liposomes and MRI-controlled focused ultrasound hyperthermia.

Int J Hyperthermia 2012 ;28(8):776-87

Centre for Research in Image-Guided Therapeutics, Sunnybrook Research Institute, Toronto, Ontario, Canada.

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http://dx.doi.org/10.3109/02656736.2012.736670DOI Listing
April 2013

Calculation of intravascular signal in dynamic contrast enhanced-MRI using adaptive complex independent component analysis.

IEEE Trans Med Imaging 2013 Apr 12;32(4):699-710. Epub 2012 Dec 12.

Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 2M9 Canada.

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http://dx.doi.org/10.1109/TMI.2012.2233747DOI Listing
April 2013

Real-time correction by optical tracking with integrated geometric distortion correction for reducing motion artifacts in functional MRI.

Magn Reson Med 2013 Mar 14;69(3):734-48. Epub 2012 May 14.

Rotman Research Institute, Baycrest, Toronto, Canada.

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http://dx.doi.org/10.1002/mrm.24309DOI Listing
March 2013

Development of a new control strategy for 3D MRI-controlled interstitial ultrasound cancer therapy.

Med Phys 2013 Mar;40(3):033301

Department of Electrical and Computer Engineering, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1118/1.4793261DOI Listing
March 2013

MR imaging-controlled transurethral ultrasound therapy for conformal treatment of prostate tissue: initial feasibility in humans.

Radiology 2012 Oct 28;265(1):303-13. Epub 2012 Aug 28.

Imaging Research, Sunnybrook Research Institute, 2075 Bayview Ave, Room C713, Toronto, ON, Canada M4N 3M5.

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http://dx.doi.org/10.1148/radiol.12112263DOI Listing
October 2012

Arterial input function calculation in dynamic contrast-enhanced MRI: an in vivo validation study using co-registered contrast-enhanced ultrasound imaging.

Eur Radiol 2012 Aug 27;22(8):1735-47. Epub 2012 Mar 27.

Department of Medical Biophysics, Sunnybrook Research Institute, University of Toronto, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada.

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http://dx.doi.org/10.1007/s00330-012-2418-1DOI Listing
August 2012

Investigation of power and frequency for 3D conformal MRI-controlled transurethral ultrasound therapy with a dual frequency multi-element transducer.

Int J Hyperthermia 2012 ;28(1):87-104

Imaging Research, Sunnybrook Health Sciences Centre, and Department of Medical Biophysics, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.3109/02656736.2011.622343DOI Listing
May 2012

Hyperthermia in bone generated with MR imaging-controlled focused ultrasound: control strategies and drug delivery.

Radiology 2012 Apr;263(1):117-27

Centre for Research in Image-Guided Therapeutics, Sunnybrook Health Sciences Centre, Toronto, ON, Canada M4N 3M5.

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http://pubs.rsna.org/doi/10.1148/radiol.11111189
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http://dx.doi.org/10.1148/radiol.11111189DOI Listing
April 2012

Thermally-triggered 'off-on-off' response of gadolinium-hydrogel-lipid hybrid nanoparticles defines a customizable temperature window for non-invasive magnetic resonance imaging thermometry.

J Control Release 2012 Feb 10;157(3):478-84. Epub 2011 Sep 10.

Department of Pharmaceutical Sciences, Leslie L. Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada M5S 3M2.

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http://dx.doi.org/10.1016/j.jconrel.2011.09.061DOI Listing
February 2012

The feasibility of endorectal MR elastography for prostate cancer localization.

Magn Reson Med 2011 Dec 13;66(6):1649-57. Epub 2011 May 13.

Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/mrm.22967DOI Listing
December 2011

New pyrazolyl and thienyl aminohydantoins as potent BACE1 inhibitors: exploring the S2' region.

Bioorg Med Chem Lett 2011 Sep 23;21(18):5164-70. Epub 2011 Jul 23.

Pfizer Neuroscience Princeton, 865 Ridge Road, Monmouth Junction, NJ 08852, USA.

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http://dx.doi.org/10.1016/j.bmcl.2011.07.057DOI Listing
September 2011

Localised drug release using MRI-controlled focused ultrasound hyperthermia.

Int J Hyperthermia 2011 15;27(2):156-71. Epub 2010 Dec 15.

Centre for Research in Image-Guided Therapeutics, Sunnybrook Health Sciences Centre, Toronto, Canada.

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http://dx.doi.org/10.3109/02656736.2010.518198DOI Listing
June 2011

Transurethral prostate magnetic resonance elastography: prospective imaging requirements.

Magn Reson Med 2011 Feb 29;65(2):340-9. Epub 2010 Sep 29.

Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/mrm.22633DOI Listing
February 2011

MRI-controlled transurethral ultrasound therapy for localised prostate cancer.

Int J Hyperthermia 2010 ;26(8):804-21

Imaging Research, Centre for Research in Image-Guided Therapeutics, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.3109/02656736.2010.503670DOI Listing
February 2011

Development of a platform for co-registered ultrasound and MR contrast imaging in vivo.

Phys Med Biol 2011 Feb 17;56(3):861-77. Epub 2011 Jan 17.

Sunnybrook Health Sciences Centre, Imaging Research, Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1088/0031-9155/56/3/020DOI Listing
February 2011

MRI-guided transurethral ultrasound therapy of the prostate gland using real-time thermal mapping: initial studies.

Urology 2010 Dec 14;76(6):1506-11. Epub 2010 Aug 14.

Department of Urology, University of Toronto, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.urology.2010.04.046DOI Listing
December 2010

A lead discovery strategy driven by a comprehensive analysis of proteases in the peptide substrate space.

Protein Sci 2010 Nov;19(11):2096-109

Lead Discovery Informatics, Lead Finding Platform, Novartis Institutes for BioMedical Research, Inc., 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1002/pro.490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005781PMC
November 2010

4-(Pyrazol-4-yl)-pyrimidines as selective inhibitors of cyclin-dependent kinase 4/6.

J Med Chem 2010 Nov 1;53(22):7938-57. Epub 2010 Nov 1.

Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA. youngshin.cho@novartis

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http://dx.doi.org/10.1021/jm100571nDOI Listing
November 2010

Simulation study on the heating of the surrounding anatomy during transurethral ultrasound prostate therapy: a 3D theoretical analysis of patient safety.

Med Phys 2010 Jun;37(6):2862-75

Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada.

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http://doi.wiley.com/10.1118/1.3426313
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http://dx.doi.org/10.1118/1.3426313DOI Listing
June 2010

Influence of exposure time and pressure amplitude on blood-brain-barrier opening using transcranial ultrasound exposures.

ACS Chem Neurosci 2010 May;1(5):391-398

Imaging Research, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

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http://dx.doi.org/10.1021/cn9000445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885821PMC
May 2010

Pyridinyl aminohydantoins as small molecule BACE1 inhibitors.

Bioorg Med Chem Lett 2010 Apr 12;20(7):2326-9. Epub 2010 Feb 12.

Department of Chemical Sciences, Wyeth Research, CN 8000, Princeton, NJ 08543-8000, United States.

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http://dx.doi.org/10.1016/j.bmcl.2010.01.136DOI Listing
April 2010

In vivo MR elastography of the prostate gland using a transurethral actuator.

Magn Reson Med 2009 Sep;62(3):665-71

Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/mrm.22038
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http://dx.doi.org/10.1002/mrm.22038DOI Listing
September 2009

Analysis of the spatial and temporal accuracy of heating in the prostate gland using transurethral ultrasound therapy and active MR temperature feedback.

Phys Med Biol 2009 May 8;54(9):2615-33. Epub 2009 Apr 8.

Imaging Research, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.

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http://dx.doi.org/10.1088/0031-9155/54/9/002DOI Listing
May 2009

An MRI-compatible system for focused ultrasound experiments in small animal models.

Med Phys 2009 May;36(5):1867-74

Imaging Research, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736709PMC
http://dx.doi.org/10.1118/1.3115680DOI Listing
May 2009

Crystal structure of human CDK4 in complex with a D-type cyclin.

Proc Natl Acad Sci U S A 2009 Mar 23;106(11):4166-70. Epub 2009 Feb 23.

Astex Therapeutics Ltd., 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0809645106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657441PMC
March 2009

Triad of polar residues implicated in pH specificity of acidic mammalian chitinase.

Protein Sci 2009 Mar;18(3):569-78

Department of Chemical and Screening Sciences, Structural Biology and Computational Chemistry, Wyeth Research, Cambridge, Massachusetts 02140, USA.

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http://dx.doi.org/10.1002/pro.63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760363PMC
March 2009

Quantitative analysis of 3-D conformal MRI-guided transurethral ultrasound therapy of the prostate: theoretical simulations.

Int J Hyperthermia 2009 Mar;25(2):116-31

Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1080/02656730802578802DOI Listing
March 2009

In vivo monitoring of focused ultrasound surgery using local harmonic motion.

Ultrasound Med Biol 2009 Jan 21;35(1):65-78. Epub 2008 Sep 21.

Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ultrasmedbio.2008.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628756PMC
January 2009

MRI-compatible transurethral ultrasound system for the treatment of localized prostate cancer using rotational control.

Med Phys 2008 Apr;35(4):1346-57

Sunnybrook Health Sciences Centre, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1118/1.2841937DOI Listing
April 2008

Progress in multimodality imaging: truly simultaneous ultrasound and magnetic resonance imaging.

IEEE Trans Med Imaging 2007 Dec;26(12):1740-6

Imaging Research Department at Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862902PMC
http://dx.doi.org/10.1109/tmi.2007.903572DOI Listing
December 2007

Thiophene substituted acylguanidines as BACE1 inhibitors.

Bioorg Med Chem Lett 2007 Oct 11;17(19):5353-6. Epub 2007 Aug 11.

Chemical and Screening Sciences, Wyeth Research, CN8000, Princeton, NJ 08543-8000, USA.

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http://dx.doi.org/10.1016/j.bmcl.2007.08.010DOI Listing
October 2007

Prostate tissue analysis immediately following magnetic resonance imaging guided transurethral ultrasound thermal therapy.

J Urol 2007 Sep 20;178(3 Pt 1):1080-5. Epub 2007 Jul 20.

Research and Anatomic Pathology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S002253470701136
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http://dx.doi.org/10.1016/j.juro.2007.05.011DOI Listing
September 2007

Identification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymerase.

J Med Chem 2007 May 3;50(9):2108-16. Epub 2007 Apr 3.

Chemical and Screening Sciences and Infectious Diseases Research, Wyeth Research, 401 N. Middletown Road, Pearl River, New York 10965, USA.

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http://dx.doi.org/10.1021/jm061428xDOI Listing
May 2007