Raj Ramesar

Raj Ramesar

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Raj Ramesar

Raj Ramesar

Publications by authors named "Raj Ramesar"

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A case-control study of risk factors for colorectal cancer in an African population.

Eur J Cancer Prev 2019 05;28(3):145-150

MRC/UCT Human Genetics Research Unit, Division of Human Genetics, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1097/CEJ.0000000000000439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076991PMC
May 2019

Human Leukocyte Antigen (HLA) Class II -DRB1 and -DQB1 Alleles and the Association with Cervical Cancer in HIV/HPV Co-Infected Women in South Africa.

J Cancer 2019 20;10(10):2145-2152. Epub 2019 May 20.

Institute of Infectious Disease and Molecular Medicine, Department of Pathology, Faculty of Health Sciences, University of Cape Town, South Africa.

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http://www.jcancer.org/v10p2145.htm
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http://dx.doi.org/10.7150/jca.25600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584421PMC
May 2019

Dietary patterns and colorectal cancer risk in Zimbabwe: A population based case-control study.

Cancer Epidemiol 2018 12 1;57:33-38. Epub 2018 Oct 1.

Department of Community Medicine, College of Health Sciences, University of Zimbabwe, PO Box A178, Avondale, Harare, Zimbabwe.

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http://dx.doi.org/10.1016/j.canep.2018.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291434PMC
December 2018

A Systematic Review of Molecular Autopsy Studies in Sudden Infant Death Cases.

J Pediatr Genet 2018 Dec 18;7(4):143-149. Epub 2018 Aug 18.

MRC/UCT Research Unit for Genomic and Precision Medicine, Division of Human Genetics, Institute of Infectious Diseases and Molecular Medicine, Department of Pathology, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1055/s-0038-1668079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234044PMC
December 2018

A review of the optimisation of the use of formalin fixed paraffin embedded tissue for molecular analysis in a forensic post-mortem setting.

Forensic Sci Int 2017 Nov 13;280:181-187. Epub 2017 Oct 13.

Division of Forensic Medicine and Toxicology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, 7925, South Africa; MRC/UCT Human Genetics Research Unit, Division of Human Genetics, Department of Pathology, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Science, University of Cape Town, Anzio Road, Observatory, Cape Town, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.forsciint.2017.09.020DOI Listing
November 2017

Ethical considerations in forensic genetics research on tissue samples collected post-mortem in Cape Town, South Africa.

BMC Med Ethics 2017 Nov 29;18(1):66. Epub 2017 Nov 29.

Department of Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, Cape Town, 7925, South Africa.

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https://bmcmedethics.biomedcentral.com/articles/10.1186/s129
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http://dx.doi.org/10.1186/s12910-017-0225-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708083PMC
November 2017

Genetic variation within GRIN2B in adolescents with alcohol use disorder may be associated with larger left posterior cingulate cortex volume.

Acta Neuropsychiatr 2017 Aug 8;29(4):252-258. Epub 2016 Aug 8.

2Department of Psychiatry and Mental Health,MRC Unit on Anxiety & Stress Disorders,University of Cape Town,Observatory,Cape Town,South Africa.

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http://dx.doi.org/10.1017/neu.2016.41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478461PMC
August 2017

The shifting epidemiology of colorectal cancer in sub-Saharan Africa.

Lancet Gastroenterol Hepatol 2017 05 18;2(5):377-383. Epub 2017 Mar 18.

MRC/UCT Human Genetics Research Unit, Division of Human Genetics, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1016/S2468-1253(16)30183-2DOI Listing
May 2017

Molecular Diagnosis of Inherited Retinal Diseases in Indigenous African Populations by Whole-Exome Sequencing.

Invest Ophthalmol Vis Sci 2016 11;57(14):6374-6381

Neurobiology, Neurodegeneration & Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States.

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http://dx.doi.org/10.1167/iovs.16-19785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132076PMC
November 2016

The incidence and histo-pathological characteristics of colorectal cancer in a population based cancer registry in Zimbabwe.

Cancer Epidemiol 2016 10 16;44:96-100. Epub 2016 Aug 16.

Department of Medicine, College of Health Sciences, University of Zimbabwe, P.O. Box A178, Avondale, Harare, Zimbabwe.

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http://dx.doi.org/10.1016/j.canep.2016.08.001DOI Listing
October 2016

Toward a Global Roadmap for Precision Medicine in Psychiatry: Challenges and Opportunities.

OMICS 2016 10 16;20(10):557-564. Epub 2016 Sep 16.

1 Department of Psychiatry and Mental Health, University of Cape Town , Cape Town, South Africa .

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http://dx.doi.org/10.1089/omi.2016.0110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453498PMC
October 2016

Minimum information required for a DMET experiment reporting.

Pharmacogenomics 2016 09 22;17(14):1533-45. Epub 2016 Aug 22.

Laboratory of Pharmacogenomics, Section of Neuroscience & Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, sp 8 Sestu-Monserrato, Km 0.700, 09042 Cagliari, Italy.

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http://dx.doi.org/10.2217/pgs-2016-0015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123892PMC
September 2016

Pharmacokinetics of rosuvastatin in 30 healthy Zimbabwean individuals of African ancestry.

Br J Clin Pharmacol 2016 07 13;82(1):326-8. Epub 2016 Apr 13.

African Institute of Biomedical Sciences and Technology, Wilkins Hospital, Harare, Zimbabwe.

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http://dx.doi.org/10.1111/bcp.12915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917814PMC
July 2016

Glutamatergic and HPA-axis pathway genes in bipolar disorder comorbid with alcohol- and substance use disorders.

Metab Brain Dis 2016 Feb 12;31(1):183-9. Epub 2015 Nov 12.

Department of Psychiatry and Mental Health, University of Cape Town, Observatory, Cape Town, South Africa.

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http://dx.doi.org/10.1007/s11011-015-9762-1DOI Listing
February 2016

Obesity, Aspirin, and Risk of Colorectal Cancer in Carriers of Hereditary Colorectal Cancer: A Prospective Investigation in the CAPP2 Study.

J Clin Oncol 2015 Nov 17;33(31):3591-7. Epub 2015 Aug 17.

Mohammad Movahedi, Beheshti University of Medical Sciences, Tehran, Iran; Mohammad Movahedi and D. Timothy Bishop, University of Leeds, Leeds; Diana Eccles, University of Southampton, Southampton; D. Gareth Evans, St Mary's Hospital, Manchester; Eamonn R. Maher, University of Birmingham, Birmingham; Malcolm G. Dunlop, Western General Hospital, Edinburgh; Shirley V. Hodgson, St George's Hospital; Lucy Side, University College London; Huw J.W. Thomas, St Mark's Hospital, Imperial College, London; Patrick J. Morrison, Queens University Belfast, Belfast City Hospital Health and Social Care Trust, Belfast; Victoria Murday, Yorkhill Hospital, Glasgow; John Burn and John C. Mathers, Newcastle University, Newcastle upon Tyne, United Kingdom; Finlay Macrae, Royal Melbourne Hospital, Melbourne, Victoria; Rodney J. Scott, John Hunter Hospital, New Lambton, New South Wales, Australia; Jukka-Pekka Mecklin, Jyväskylä Central Hospital, Jyväskylä, Finland; Gabriela Moeslein, HELIOS St Josefs Hospital, Bochum-Linden, Germany; Sylviane Olschwang, Institut Paoli Calmettes, Marseille, France; Lucio Bertario, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy; Marie-Luise Bisgaard, University of Copenhagen, Hvidovre, Denmark; Judy W.C. Ho, Queen Mary Hospital, Hong Kong, Special Administrative Region, People's Republic of China; Annika Lindblom, Karolinska Institutet, Stockholm, Sweden; Jan Lubinski, International Hereditary Cancer Centre, Szczecin, Poland; Raj S. Ramesar, University of Cape Town, South Africa; and Hans F. Vasen, Netherlands Foundation of the Detection of Hereditary Tumours and Leiden University, Leiden, the Netherlands.

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http://dx.doi.org/10.1200/JCO.2014.58.9952DOI Listing
November 2015

Large Scale Genetic Research on Neuropsychiatric Disorders in African Populations is Needed.

EBioMedicine 2015 Oct 9;2(10):1259-61. Epub 2015 Oct 9.

Stanley Center for Psychiatric Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA ; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA ; Psychiatric and Neurodevelopmental Genetics Unit and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.ebiom.2015.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634677PMC
October 2015

Relationship between sunlight and the age of onset of bipolar disorder: an international multisite study.

J Affect Disord 2014 29;167:104-11. Epub 2014 May 29.

Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles (UCLA), Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.jad.2014.05.032DOI Listing
May 2015

Influence of light exposure during early life on the age of onset of bipolar disorder.

J Psychiatr Res 2015 May 27;64:1-8. Epub 2015 Mar 27.

Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior University of California Los Angeles (UCLA), Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.jpsychires.2015.03.013DOI Listing
May 2015

The importance of G protein-coupled receptor kinase 4 (GRK4) in pathogenesis of salt sensitivity, salt sensitive hypertension and response to antihypertensive treatment.

Int J Mol Sci 2015 Mar 12;16(3):5741-9. Epub 2015 Mar 12.

MRC Human Genetics Research Unit, Division of Human Genetics, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town 7925, South Africa.

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http://dx.doi.org/10.3390/ijms16035741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394502PMC
March 2015

Association of variants at BCL11A and HBS1L-MYB with hemoglobin F and hospitalization rates among sickle cell patients in Cameroon.

PLoS One 2014 25;9(3):e92506. Epub 2014 Mar 25.

Department of Microbiology, Parasitology and Haematology, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092506PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965431PMC
January 2015

Genomics: African dawn.

Authors:
Raj Ramesar

Nature 2015 Jan 3;517(7534):276-7. Epub 2014 Dec 3.

MRC Human Genetics Research Unit, Division of Human Genetics, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Observatory 7925, South Africa.

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http://dx.doi.org/10.1038/nature14077DOI Listing
January 2015

Psychosocial stressors of sickle cell disease on adult patients in Cameroon.

J Genet Couns 2014 Dec 21;23(6):948-56. Epub 2014 Feb 21.

Division of Human Genetics, Faculty of Health Sciences, University of Cape Town (UCT), Anzio road-7925, Observatory, Cape Town, South Africa,

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http://dx.doi.org/10.1007/s10897-014-9701-zDOI Listing
December 2014

Would you terminate a pregnancy affected by sickle cell disease? Analysis of views of patients in Cameroon.

J Med Ethics 2014 Sep 5;40(9):615-20. Epub 2013 Aug 5.

Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.

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http://dx.doi.org/10.1136/medethics-2013-101392DOI Listing
September 2014

Coinheritance of sickle cell anemia and α-thalassemia delays disease onset and could improve survival in Cameroonian's patients (Sub-Saharan Africa).

Am J Hematol 2014 Jun 10;89(6):664-5. Epub 2014 Apr 10.

Division of Human Genetics, Institute of Infectious Disease and Molecular Medicine (IDM), Faculty of Health Sciences, University of Cape Town (UCT), Cape Town, Republic of South Africa.

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http://dx.doi.org/10.1002/ajh.23711DOI Listing
June 2014

A mutation in a splicing factor that causes retinitis pigmentosa has a transcriptome-wide effect on mRNA splicing.

BMC Res Notes 2014 Jun 27;7:401. Epub 2014 Jun 27.

School of Mathematics, Statistics and Applied Mathematics, National University of Ireland, Galway, University Road, Galway, Republic of Ireland.

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http://dx.doi.org/10.1186/1756-0500-7-401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084799PMC
June 2014

Determining ancestry proportions in complex admixture scenarios in South Africa using a novel proxy ancestry selection method.

PLoS One 2013 16;8(9):e73971. Epub 2013 Sep 16.

Computational Biology Group, Department of Clinical Laboratory Sciences, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Medical School, Cape Town, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0073971PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774743PMC
May 2014

Psychosocial burden of sickle cell disease on parents with an affected child in Cameroon.

J Genet Couns 2014 Apr 24;23(2):192-201. Epub 2013 Jul 24.

Division of Human Genetics, Faculty of Health Sciences, University of Cape Town (UCT), Anzio road-7925, Observatory, Cape Town, South Africa,

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http://dx.doi.org/10.1007/s10897-013-9630-2DOI Listing
April 2014

Communicating cancer risk within an African context: experiences, disclosure patterns and uptake rates following genetic testing for Lynch syndrome.

Patient Educ Couns 2013 Jul 28;92(1):53-60. Epub 2013 Feb 28.

MRC/UCT Human Genetics Research Unit, IIDMM Faculty of Health Sciences, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.

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http://dx.doi.org/10.1016/j.pec.2013.02.001DOI Listing
July 2013

Direct-to-consumer genetic testing: to test or not to test, that is the question.

S Afr Med J 2013 Jul 4;103(8):510-2. Epub 2013 Jul 4.

Division of Human Genetics, University of Cape Town, South Africa.

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http://dx.doi.org/10.7196/samj.7049DOI Listing
July 2013

A mobile colonoscopic unit for lynch syndrome: trends in surveillance uptake and patient experiences of screening in a developing country.

J Genet Couns 2013 Feb 9;22(1):125-37. Epub 2013 Jan 9.

MRC/UCT Human Genetics Research Unit, Division of Human Genetics, Institute for Infectious Diseases and Molecular Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.

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http://dx.doi.org/10.1007/s10897-012-9523-9DOI Listing
February 2013

UCT's contribution to medical genetics in Africa - from the past into the future.

S Afr Med J 2012 Mar 2;102(6):446-8. Epub 2012 Mar 2.

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March 2012

Beyond the Caster Semenya controversy: the case of the use of genetics for gender testing in sport.

J Genet Couns 2010 Dec 8;19(6):545-8. Epub 2010 Sep 8.

Division of Human Genetics, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1007/s10897-010-9320-2DOI Listing
December 2010

Catechol-o-methyltransferase genotype and childhood trauma may interact to impact schizotypal personality traits.

Behav Genet 2010 May 22;40(3):415-23. Epub 2009 Dec 22.

MRC/UCT Human Genetics Research Unit, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1007/s10519-009-9323-7DOI Listing
May 2010

The extracolonic cancer spectrum in females with the common 'South African' hMLH1 c.C1528T mutation.

Fam Cancer 2008 30;7(3):191-8. Epub 2007 Nov 30.

Division of Human Genetics, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1007/s10689-007-9174-4DOI Listing
January 2009

South Africa: from species cradle to genomic applications.

Nat Rev Genet 2008 10;9 Suppl 1:S19-23

McLaughlin-Rotman Centre for Global Health, Program on Life Sciences, Ethics and Policy, University Health Network and University of Toronto, MaRS Centre, Toronto, Ontario M5G 1L7, Canada.

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http://dx.doi.org/10.1038/nrg2441DOI Listing
October 2008

Preliminary evidence for linkage to chromosome 1q31-32, 10q23.3, and 16p13.3 in a South African cohort with bipolar disorder.

Am J Med Genet B Neuropsychiatr Genet 2007 Apr;144B(3):383-7

Division of Human Genetics, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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http://doi.wiley.com/10.1002/ajmg.b.30461
Publisher Site
http://dx.doi.org/10.1002/ajmg.b.30461DOI Listing
April 2007