Publications by authors named "Rainer Blasczyk"

100Publications

Immunogenetics of xenotransplantation.

Int J Immunogenet 2021 Jan 7. Epub 2021 Jan 7.

Institute of Transfusion Medicine and Transplant Engineering, Hannover Medical School, Hannover, Germany.

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January 2021

The Loss of HLA-F/KIR3DS1 Ligation Is Mediated by Hemoglobin Peptides.

Int J Mol Sci 2020 Oct 28;21(21). Epub 2020 Oct 28.

Institute for Transfusion Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

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October 2020

Towards Reduction or Substitution of Cytotoxic DMSO in Biobanking of Functional Bioengineered Megakaryocytes.

Int J Mol Sci 2020 Oct 16;21(20). Epub 2020 Oct 16.

Institute of Transfusion Medicine and Transplant Engineering, Hannover Medical School, 30625 Hannover, Germany.

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October 2020

Isolation, Cryopreservation, and Characterization of iPSC-Derived Megakaryocytes.

Methods Mol Biol 2021 ;2180:539-554

Institute of Transfusion Medicine and Transplant Engineering, Hannover Medical School, Hannover, Germany.

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January 2021

Reappearance of effector T cells is associated with recovery from COVID-19.

EBioMedicine 2020 Jul 7;57:102885. Epub 2020 Jul 7.

Institute of Immunology, Hannover Medical School, Germany; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Germany. Electronic address:

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July 2020

NKG2A/CD94 Is a New Immune Receptor for HLA-G and Distinguishes Amino Acid Differences in the HLA-G Heavy Chain.

Int J Mol Sci 2020 Jun 19;21(12). Epub 2020 Jun 19.

Institute of Transfusion Medicine and Transplant Engineering, Hannover Medical School, 30625 Hannover, Germany.

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June 2020

High-intensity interval training in allogeneic adoptive T-cell immunotherapy - a big HIT?

J Transl Med 2020 04 1;18(1):148. Epub 2020 Apr 1.

Institute of Transfusion Medicine and Transplant Engineering, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Germany.

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April 2020

HLA-F Allele-Specific Peptide Restriction Represents an Exceptional Proteomic Footprint.

Int J Mol Sci 2019 Nov 8;20(22). Epub 2019 Nov 8.

Institute for Transfusion Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

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November 2019

The Mechanistic Differences in HLA-Associated Carbamazepine Hypersensitivity.

Pharmaceutics 2019 Oct 15;11(10). Epub 2019 Oct 15.

Institute for Transfusion Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

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October 2019

Battle between Host Immune Cellular Responses and HCMV Immune Evasion.

Int J Mol Sci 2019 Jul 24;20(15). Epub 2019 Jul 24.

Institute for Transfusion Medicine, Hannover Medical School, 30625 Hannover, Germany.

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July 2019

Correction to: HLA-F*01:01 presents peptides with N-terminal flexibility and a preferred length of 16 residues.

Immunogenetics 2019 May;71(5-6):361

Institute for Transfusion Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.

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May 2019

HLA-F*01:01 presents peptides with N-terminal flexibility and a preferred length of 16 residues.

Immunogenetics 2019 05 2;71(5-6):353-360. Epub 2019 Apr 2.

Institute for Transfusion Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.

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May 2019

Between Innate and Adaptive Immune Responses: NKG2A, NKG2C, and CD8⁺ T Cell Recognition of HLA-E Restricted Self-Peptides Acquired in the Absence of HLA-Ia.

Int J Mol Sci 2019 Mar 22;20(6). Epub 2019 Mar 22.

Institute for Transfusion Medicine, Hannover Medical School, Medical Park, Feodor-Lynen-Str. 5, 30625 Hannover, Germany.

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March 2019

The polymorphism at residue 156 determines the HLA-B*35 restricted peptide repertoire during HCMV infection.

Immunogenetics 2018 11 21;70(10):639-646. Epub 2018 Aug 21.

Institute for Transfusion Medicine, Hannover Medical School, Hannover, Germany.

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November 2018

Characterization of induced pluripotent stem cell-derived megakaryocyte lysates for potential regenerative applications.

J Cell Mol Med 2018 09 12;22(9):4545-4549. Epub 2018 Jun 12.

Institute for Transfusion Medicine, Hannover Medical School, Hannover, Germany.

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September 2018

HLA-G mediated immune regulation is impaired by a single amino acid exchange in the alpha 2 domain.

Hum Immunol 2018 Jun 29;79(6):453-462. Epub 2018 Mar 29.

Institute for Transfusion Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany. Electronic address:

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June 2018

HLA-G peptide preferences change in transformed cells: impact on the binding motif.

Immunogenetics 2018 08 30;70(8):485-494. Epub 2018 Mar 30.

Institute for Transfusion Medicine, Hannover Medical School, Medical Park, Feodor-Lynen-Str. 21, 30625, Hannover, Germany.

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August 2018

Low Immunogenic Endothelial Cells Maintain Morphological and Functional Properties Required for Vascular Tissue Engineering.

Tissue Eng Part A 2018 03 19;24(5-6):432-447. Epub 2017 Dec 19.

1 Lower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), Hannover Medical School , Hannover, Germany .

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March 2018

Towards the Manufacture of Megakaryocytes and Platelets for Clinical Application.

Transfus Med Hemother 2017 Jun 23;44(3):165-173. Epub 2017 May 23.

Institute for Transfusion Medicine, Hanover Medical School, Hanover, Germany.

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June 2017

Comparative Analysis of Clinical-Scale IFN-γ-Positive T-Cell Enrichment Using Partially and Fully Integrated Platforms.

Front Immunol 2016 30;7:393. Epub 2016 Sep 30.

Institute of Cellular Therapeutics, Hannover Medical School, Niedersachsen, Germany; Integrated Research and Treatment Center Transplantation (IFB-Tx), Hannover Medical School, Niedersachsen, Germany.

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September 2016

Understanding the obstacle of incompatibility at residue 156 within HLA-B*35 subtypes.

Immunogenetics 2016 Apr 12;68(4):247-60. Epub 2016 Jan 12.

Hannover Medical School, Institute for Transfusion Medicine, Feodor-Lynen-Str. 5, 30625, Hannover, Germany.

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April 2016

IgM-Enriched Human Intravenous Immunoglobulin-Based Treatment of Patients With Early Donor Specific Anti-HLA Antibodies After Lung Transplantation.

Transplantation 2016 Dec;100(12):2682-2692

1 Department of Cardiothoracic, Transplant and Vascular Surgery, Hanover Medical School, Hanover, Germany.2 Department of Transfusion Medicine, Hanover Medical School, Hanover, Germany.3 Department of Hypertension and Nephrology, Hanover Medical School, Hanover, Germany.4 Division of Patient Care, Hanover Medical School, Hanover, Germany.5 Department of Respiratory Medicine, Hanover Medical School, Hanover, Germany.6 Department of Paediatric Pneumology, Hanover Medical School, Hanover, Germany.

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December 2016

Human leucocyte antigens and pediatric autoimmune liver disease: diagnosis and prognosis.

Eur J Pediatr 2016 Apr 14;175(4):527-37. Epub 2015 Nov 14.

Pediatric Gastroenterology and Hepatology, Department of Paediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Carl- Neuberg-Str 1, 30625, Hannover, Niedersachsen, Germany.

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April 2016

The diversity of the HLA-E-restricted peptide repertoire explains the immunological impact of the Arg107Gly mismatch.

Immunogenetics 2016 Jan 9;68(1):29-41. Epub 2015 Nov 9.

Institute for Transfusion Medicine, Hannover Medical School, Medical Park, Feodor-Lynen-Str. 5, 30625, Hannover, Germany.

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January 2016

HLA-E: Presentation of a Broader Peptide Repertoire Impacts the Cellular Immune Response-Implications on HSCT Outcome.

Stem Cells Int 2015 12;2015:346714. Epub 2015 Aug 12.

Institute for Transfusion Medicine, Hannover Medical School, 30625 Hannover, Germany.

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September 2015

The c.503T>C Polymorphism in the Human KLRB1 Gene Alters Ligand Binding and Inhibitory Potential of CD161 Molecules.

PLoS One 2015 26;10(8):e0135682. Epub 2015 Aug 26.

Transplant Laboratory, Department for General-, Visceral- and Transplantation Surgery, Hannover Medical School, Hannover, Germany.

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June 2016

Molecular and cellular characteristics of human and non-human primate multipotent stromal cells from the amnion and bone marrow during long term culture.

Stem Cell Res Ther 2015 Aug 22;6:150. Epub 2015 Aug 22.

Institute for Transfusion Medicine, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Germany.

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August 2015

miR-145 Is a Promising Therapeutic Target to Prevent Cornea Scarring.

Hum Gene Ther 2015 Oct 16;26(10):698-707. Epub 2015 Sep 16.

1 Institute for Transfusion Medicine, Hannover Medical School , Hannover, Germany .

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October 2015

Oncogenic acidic nuclear phosphoproteins ANP32C/D are novel clients of heat shock protein 90.

Biochim Biophys Acta 2015 Oct 22;1853(10 Pt A):2338-48. Epub 2015 Jun 22.

Institute for Transfusion Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, D-30625 Hannover, Germany. Electronic address:

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October 2015

miR-145 Contributes to Hypertrophic Scarring of the Skin by Inducing Myofibroblast Activity.

Mol Med 2015 Apr 9;21:296-304. Epub 2015 Apr 9.

Institute for Transfusion Medicine, Hannover Medical School, Hannover, Germany.

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April 2015

A Micropolymorphism Altering the Residue Triad 97/114/156 Determines the Relative Levels of Tapasin Independence and Distinct Peptide Profiles for HLA-A(*)24 Allotypes.

J Immunol Res 2014 4;2014:298145. Epub 2014 Dec 4.

Institute for Transfusion Medicine, Hannover Medical School, Medical Park, Feodor Lynen Street 21, 30625 Hannover, Germany.

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December 2015

HLA-E: a novel player for histocompatibility.

J Immunol Res 2014 20;2014:352160. Epub 2014 Oct 20.

Institute for Transfusion Medicine, Hannover Medical School, Medical Park, Feodor-Lynen-Straße 5, 30625 Hannover, Germany.

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June 2015

Soluble HLA technology as a strategy to evaluate the impact of HLA mismatches.

J Immunol Res 2014 1;2014:246171. Epub 2014 Sep 1.

Institute for Transfusion Medicine, Hannover Medical School, Medical Park, Feodor-Lynen-Straße 5, 30625 Hannover, Germany.

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June 2015

Evaluation of suitable target antigens and immunoassays for high-accuracy immune monitoring of cytomegalovirus and Epstein-Barr virus-specific T cells as targets of interest in immunotherapeutic approaches.

J Immunol Methods 2014 Jun 28;408:101-13. Epub 2014 May 28.

Institute for Transfusion Medicine, Hannover Medical School, Hannover, Germany; Integrated Research and Treatment Center (IFB-Tx), Hannover Medical School, Hannover Germany. Electronic address:

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June 2014

Variants of a Thermus aquaticus DNA polymerase with increased selectivity for applications in allele- and methylation-specific amplification.

PLoS One 2014 6;9(5):e96640. Epub 2014 May 6.

Department of Chemistry, Konstanz Research School Chemical Biology, University of Konstanz, Konstanz, Germany.

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June 2015

PECAM-1-dependent heme oxygenase-1 regulation via an Nrf2-mediated pathway in endothelial cells.

Thromb Haemost 2014 Jun 6;111(6):1077-88. Epub 2014 Feb 6.

Dr. Stephan Immenschuh, Institute for Transfusion Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany, Tel.: +49 511 532 6704, Fax: +49 511 532 2079, E-mail:

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June 2014

MHC universal cells survive in an allogeneic environment after incompatible transplantation.

Biomed Res Int 2013 9;2013:796046. Epub 2013 Oct 9.

Institute for Transfusion Medicine, Hannover Medical School, Lower Saxony, 30625 Hannover, Germany.

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August 2014

Overexpression of the pp32r1 (ANP32C) oncogene or its functional mutant pp32r1Y140H confers enhanced resistance to FTY720 (Finguimod).

Cancer Biol Ther 2014 Mar 12;15(3):289-96. Epub 2013 Dec 12.

Institute for Transfusion Medicine; Hannover Medical School; Hannover, Germany.

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March 2014

Impaired functionality of antiviral T cells in G-CSF mobilized stem cell donors: implications for the selection of CTL donor.

PLoS One 2013 4;8(12):e77925. Epub 2013 Dec 4.

Institute for Transfusion Medicine, Hannover Medical School, Hannover, Germany ; Integrated Research and Treatment Centre Transplantation, IFB-Tx, Hannover Medical School, Hannover, Germany.

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September 2014

Autocrine GM-CSF transcription in the leukemic progenitor cell line KG1a is mediated by the transcription factor ETS1 and is negatively regulated through SECTM1 mediated ligation of CD7.

Biochim Biophys Acta 2014 Mar 6;1840(3):1004-13. Epub 2013 Nov 6.

Institute for Transfusion Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, D-30625 Hannover, Germany. Electronic address:

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March 2014

HLA-universal platelet transfusions prevent platelet refractoriness in a mouse model.

Hum Gene Ther 2013 Dec 7;24(12):1018-28. Epub 2013 Nov 7.

1 Institute for Transfusion Medicine, Hannover Medical School , 30625 Hannover, Germany .

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December 2013

CMV-, EBV- and ADV-specific T cell immunity: screening and monitoring of potential third-party donors to improve post-transplantation outcome.

Biol Blood Marrow Transplant 2013 Oct 23;19(10):1480-92. Epub 2013 Jul 23.

Institute for Transfusion Medicine, Hannover Medical School, Hannover, Germany; Integrated Research and Treatment Center (IFB-Tx), Hannover Medical School, Hannover, Germany.

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October 2013

Monitoring dendritic cell and cytokine biomarkers during remission prior to relapse in patients with FLT3-ITD acute myeloid leukemia.

Ann Hematol 2013 Aug 25;92(8):1079-90. Epub 2013 Apr 25.

Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School (MHH), OE 6860, Carl-Neuberg Strasse 1, Hannover, Germany.

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August 2013

Embryonic stem cells of the non-human primate Callithrix jacchus can be differentiated into definitive endoderm by Activin-A but not IDE-1/2.

J Tissue Eng Regen Med 2015 Apr 18;9(4):473-9. Epub 2013 Feb 18.

Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany; Institute for Transfusion Medicine, Hannover Medical School, Hannover, Germany.

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April 2015

Dysregulation of cell cycle control caused by overexpression of the oncogene pp32r1 (ANP32C) and the Tyr>His mutant pp32r1Y140H.

Biochim Biophys Acta 2013 May 8;1833(5):1212-21. Epub 2013 Feb 8.

Institute for Transfusion Medicine, Hannover Medical School, Hannover, Germany.

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May 2013

Adoptive T-cell immunotherapy from third-party donors: characterization of donors and set up of a T-cell donor registry.

Front Immunol 2012 28;3:410. Epub 2013 Jan 28.

Institute for Transfusion Medicine, Hannover Medical School Hannover, Germany.

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February 2013

Semaphorin 7A protein variants differentially regulate T-cell activity.

Transfusion 2013 Feb 31;53(2):270-83. Epub 2012 Jul 31.

Institute for Transfusion Medicine, Hannover Medical School, Hannover, Germany.

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February 2013

Residue 81 confers a restricted C-terminal peptide binding motif in HLA-B*44:09.

Immunogenetics 2012 Sep 16;64(9):663-8. Epub 2012 Jun 16.

Institute for Transfusion Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

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September 2012

IL-2 upregulates CD86 expression on human CD4(+) and CD8(+) T cells.

J Immunol 2012 Feb 13;188(4):1620-9. Epub 2012 Jan 13.

Institute for Transfusion Medicine, Hannover Medical School, D-30625 Hannover, Germany.

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February 2012

Position 45 influences the peptide binding motif of HLA-B*44:08.

Immunogenetics 2012 Mar 19;64(3):245-9. Epub 2011 Oct 19.

Institute for Transfusion Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.

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March 2012

Scoring HLA class I mismatches by HistoCheck does not predict clinical outcome in unrelated hematopoietic stem cell transplantation.

Biol Blood Marrow Transplant 2012 May 29;18(5):739-46. Epub 2011 Sep 29.

Center for International Blood and Marrow Transplant Research, Minneapolis, Minnesota 55413, USA.

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May 2012