Publications by authors named "Radhakrishnan Sabarinathan"

26Publications

Exome sequencing identifies ARID2 as a novel tumor suppressor in early-onset sporadic rectal cancer.

Oncogene 2020 Dec 1. Epub 2020 Dec 1.

Laboratory of Molecular Oncology, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, 500039, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41388-020-01537-zDOI Listing
December 2020

Twist1 induces chromosomal instability (CIN) in colorectal cancer cells.

Hum Mol Genet 2020 Jun;29(10):1673-1688

B-216, Chromosome Biology Lab (CBL), Indian Institute of Science Education and Research (IISER), Dr Homi Bhabha Road, Pashan, Pune 411008, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddaa076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322571PMC
June 2020

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.

Nature 2020 02 5;578(7793):102-111. Epub 2020 Feb 5.

The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41586-020-1965-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054214PMC
February 2020

Local Determinants of the Mutational Landscape of the Human Genome.

Cell 2019 03;177(1):101-114

Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac, 10, 08028 Barcelona, Spain; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2019.02.051DOI Listing
March 2019

A splice-site variant in the lncRNA gene cosegregates in the large Volkmann cataract family.

Mol Vis 2019 20;25:1-11. Epub 2019 Jan 20.

Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, Panum Institute, University of Copenhagen, Copenhagen N, Denmark.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377377PMC
June 2019

Multiple Sequence Alignments Enhance Boundary Definition of RNA Structures.

Genes (Basel) 2018 Dec 4;9(12). Epub 2018 Dec 4.

Center for Non-Coding RNA in Technology and Health, Department of Veterinary and Animal Sciences, University of Copenhagen, Grønnegårdsvej 3, 1870 Frederiksberg C, Denmark.

View Article

Download full-text PDF

Source
http://www.mdpi.com/2073-4425/9/12/604
Publisher Site
http://dx.doi.org/10.3390/genes9120604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315940PMC
December 2018

Somatic and Germline Mutation Periodicity Follow the Orientation of the DNA Minor Groove around Nucleosomes.

Cell 2018 11;175(4):1074-1087.e18

Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac, 10, 08028 Barcelona, Spain; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2018.10.004DOI Listing
November 2018

Author Correction: Reduced mutation rate in exons due to differential mismatch repair.

Nat Genet 2018 08;50(8):1196

Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-018-0123-yDOI Listing
August 2018

A Pan-cancer Landscape of Interactions between Solid Tumors and Infiltrating Immune Cell Populations.

Clin Cancer Res 2018 08 17;24(15):3717-3728. Epub 2018 Apr 17.

Department of Experimental and Health Sciences, University Pompeu Fabra, Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-17-3509DOI Listing
August 2018

Reduced mutation rate in exons due to differential mismatch repair.

Nat Genet 2017 Dec 6;49(12):1684-1692. Epub 2017 Nov 6.

Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712219PMC
December 2017

OncodriveFML: a general framework to identify coding and non-coding regions with cancer driver mutations.

Genome Biol 2016 06 16;17(1):128. Epub 2016 Jun 16.

Research Program on Biomedical Informatics, IMIM Hospital del Mar Medical Research Institute and Universitat Pompeu Fabra, Doctor Aiguader 88, 08003, Barcelona, Catalonia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13059-016-0994-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910259PMC
June 2016

Nucleotide excision repair is impaired by binding of transcription factors to DNA.

Nature 2016 Apr;532(7598):264-7

Research Program on Biomedical Informatics, IMIM Hospital del Mar Medical Research Institute and Universitat Pompeu Fabra, Doctor Aiguader 88, 08003 Barcelona, Spain.

View Article

Download full-text PDF

Source
http://biorxiv.org/content/biorxiv/early/2015/10/13/028886.f
Web Search
http://www.nature.com/doifinder/10.1038/nature17661
Publisher Site
http://dx.doi.org/10.1038/nature17661DOI Listing
April 2016

IL-4 orchestrates STAT6-mediated DNA demethylation leading to dendritic cell differentiation.

Genome Biol 2016 Jan 13;17. Epub 2016 Jan 13.

Chromatin and Disease Group, Cancer Epigenetics and Biology Programme (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), 08908 L'Hospitalet de Llobregat, Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13059-015-0863-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711003PMC
January 2016

Simultaneous DNA and RNA Mapping of Somatic Mitochondrial Mutations across Diverse Human Cancers.

PLoS Genet 2015 Jun 30;11(6):e1005333. Epub 2015 Jun 30.

Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1005333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488357PMC
June 2015

Profiling of ribose methylations in RNA by high-throughput sequencing.

Angew Chem Int Ed Engl 2015 Jan 21;54(2):451-5. Epub 2014 Nov 21.

Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen N (Denmark).

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/anie.201408362
Publisher Site
http://dx.doi.org/10.1002/anie.201408362DOI Listing
January 2015

Interactome analyses of Salmonella pathogenicity islands reveal SicA indispensable for virulence.

J Theor Biol 2014 Dec 13;363:188-97. Epub 2014 Aug 13.

Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtbi.2014.08.013DOI Listing
December 2014

Transcriptome-wide analysis of UTRs in non-small cell lung cancer reveals cancer-related genes with SNV-induced changes on RNA secondary structure and miRNA target sites.

PLoS One 2014 8;9(1):e82699. Epub 2014 Jan 8.

Center for non-coding RNA in Technology and Health, Section for Animal Genetics, Bioinformatics and Breeding, IKVH, University of Copenhagen, Frederiksberg, Denmark.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082699PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885406PMC
September 2014

The RNAsnp web server: predicting SNP effects on local RNA secondary structure.

Nucleic Acids Res 2013 Jul 29;41(Web Server issue):W475-9. Epub 2013 Apr 29.

Center for non-coding RNA in Technology and Health, University of Copenhagen, Grønnegårdsvej 3, 1870 Frederiksberg C, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkt291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977658PMC
July 2013

RNAsnp: efficient detection of local RNA secondary structure changes induced by SNPs.

Hum Mutat 2013 Apr;34(4):546-56

Center for non-coding RNA in Technology and Health, University of Copenhagen, Frederiksberg, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.22273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708107PMC
April 2013

Comparative genomics reveals 'novel' Fur regulated sRNAs and coding genes in diverse proteobacteria.

Gene 2013 Mar 22;516(2):335-44. Epub 2012 Dec 22.

UGC-Networking Resource Centre in Biological Sciences, Madurai Kamaraj University, Madurai-625021, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gene.2012.12.057DOI Listing
March 2013

Junker: an intergenic explorer for bacterial genomes.

Genomics Proteomics Bioinformatics 2011 Oct;9(4-5):179-82

Centre of Excellence in Bioinformatics, School of Biotechnology, Madurai Kamaraj University, Madurai 625021, Tamilnadu, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1672-0229(11)60021-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054447PMC
October 2011

FAIR: A server for internal sequence repeats.

Bioinformation 2010 Jan 7;4(7):271-5. Epub 2010 Jan 7.

Bioinformatics Centre, Centre of Excellence in Structural Biology and Bio-computing, Indian Institute of Science, Bangalore 560 012, India.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957760PMC
http://dx.doi.org/10.6026/97320630004271DOI Listing
January 2010