Prof. Pradyumna Kumar Mishra, PhD - ICMR-National Institute for Research in Environmental Health - Head (Molecular Biology)

Prof. Pradyumna Kumar Mishra

PhD

ICMR-National Institute for Research in Environmental Health

Head (Molecular Biology)

Bhopal, MP | India

Additional Specialties: Translational Research

ORCID logohttps://orcid.org/0000-0002-0795-2819

Prof. Pradyumna Kumar Mishra, PhD - ICMR-National Institute for Research in Environmental Health - Head (Molecular Biology)

Prof. Pradyumna Kumar Mishra

PhD

Introduction

Dr. Pradyumna Kumar Mishra is currently leading the Molecular Biology Group at National Institute for Research in Environmental Health, Bhopal. Earlier, he served as Scientist E, Division of Translational Research, Tata Memorial Centre, Mumbai. Dr. Mishra is a recipient of prestigious Fulbright-Nehru Fellowship (USA) and is a Visiting Faculty Associate to Weizmann Institute of Science, Israel and Osaka University, Japan.

Primary Affiliation: ICMR-National Institute for Research in Environmental Health - Bhopal, MP , India

Additional Specialties:

Research Interests:

Experience

Nov 2015 - Nov 2015
ICMR-National Institute for Research in Environmental Health, Bhopal
Head
Molecular Biology
Mar 2010 - Mar 2010
Tata Memorial Centre, Mumbai
Scientific Officer - E
Translational Research
Dec 2003 - Dec 2003
Bhopal Memorial Hospital and Research Centre, Bhopal
Associate Research Professor
Research

Publications

139Publications

766Reads

21Profile Views

141PubMed Central Citations

Exposure to ultrafine particulate matter induces NF-κβ mediated epigenetic modifications.

Environ Pollut 2019 Sep 21;252(Pt A):39-50. Epub 2019 May 21.

Department of Molecular Biology, ICMR-National Institute for Research in Environmental Health, Bhopal, India. Electronic address:

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http://dx.doi.org/10.1016/j.envpol.2019.05.065DOI Listing
September 2019
3 Reads
4.143 Impact Factor

Impairment of Mitochondrial-Nuclear Cross Talk in Lymphocytes Exposed to Landfill Leachate.

Environ Health Insights 2019 2;13:1178630219839013. Epub 2019 Apr 2.

Department of Molecular Biology, ICMR-National Institute for Research in Environmental Health, Bhopal, India.

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http://dx.doi.org/10.1177/1178630219839013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484670PMC
April 2019
2 Reads

Nanobiosensors: Point-of-care approaches for cancer diagnostics.

Biosens Bioelectron 2019 Apr 22;130:147-165. Epub 2019 Jan 22.

Department of Molecular Biology, ICMR-National Institute for Research in Environmental Health, Kamla Nehru Hospital Building, Gandhi Medical College Campus, Bhopal, India. Electronic address:

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http://dx.doi.org/10.1016/j.bios.2019.01.034DOI Listing
April 2019
6.409 Impact Factor

Nano-engineered flavonoids for cancer protection.

Front Biosci (Landmark Ed) 2019 03 1;24:1097-1157. Epub 2019 Mar 1.

Department of Molecular Biology, ICMR-National Institute for Research in Environmental Health, Bhopal, India,

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March 2019
6 Reads

Dendritic cell engineering for selective targeting of female reproductive tract cancers.

Indian J Med Res 2018 12;148(Suppl):S50-S63

Department of Molecular Biology, ICMR-National Institute for Research in Environmental Health, Bhopal, India.

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http://dx.doi.org/10.4103/ijmr.IJMR_224_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469378PMC
December 2018
1.661 Impact Factor

Cell-Free Circulating Epigenomic Signatures: Non-Invasive Biomarker for Cardiovascular and Other Age-Related Chronic Diseases.

Curr Pharm Des 2017 ;23(8):1175-1187

Department of Molecular Biology, National Institute for Research in Environmental Health (ICMR), Kamla Nehru Hospital Building (Gandhi Medical College Campus), Bhopal (MP) - 462001. India.

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http://dx.doi.org/10.2174/1381612822666161027145359DOI Listing
April 2018
34 Reads
1 Citation
3.452 Impact Factor

Ultrafine particulate matter impairs mitochondrial redox homeostasis and activates phosphatidylinositol 3-kinase mediated DNA damage responses in lymphocytes.

Environ Pollut 2018 Mar 1;234:406-419. Epub 2017 Dec 1.

Department of Molecular Biology, ICMR-National Institute for Research in Environmental Health, Bhopal, India. Electronic address:

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http://dx.doi.org/10.1016/j.envpol.2017.11.093DOI Listing
March 2018
8 Reads
4.143 Impact Factor

Nanoengineered strategies for siRNA delivery: from target assessment to cancer therapeutic efficacy.

Drug Deliv Transl Res 2017 04;7(2):346-358

Department of Molecular Biology, National Institute for Research in Environmental Health, Indian Council of Medical Research (ICMR), Bhopal, India.

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http://dx.doi.org/10.1007/s13346-016-0352-5DOI Listing
April 2017
4 Reads
3 Citations

Molecular bio-dosimetry for carcinogenic risk assessment in survivors of Bhopal gas tragedy.

Int J Occup Med Environ Health 2015 ;28(6):921-39

Tata Memorial Centre, Advanced Centre for Treatment, Research and Education in Cancer, Navi Mumbai, India (Division of Translational Research).

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http://dx.doi.org/10.13075/ijomeh.1896.00313DOI Listing
December 2016
3 Reads
1 Citation
1.094 Impact Factor

Epigenetics: A key paradigm in reproductive health.

Clin Exp Reprod Med 2016 Jun 23;43(2):59-81. Epub 2016 Jun 23.

Translational Research Laboratory, School of Biological Sciences, Dr. Hari Singh Central University, Sagar, India.; Department of Molecular Biology, National Institute for Research in Environmental Health (ICMR), Bhopal, India.

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http://dx.doi.org/10.5653/cerm.2016.43.2.59DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925870PMC
June 2016
12 Reads
4 Citations

Role of mitochondrial oxidative stress on lymphocyte homeostasis in patients diagnosed with extra-pulmonary tuberculosis.

Cell Biol Int 2016 Feb 13;40(2):166-76. Epub 2015 Oct 13.

Translational Research Laboratory, School of Biological Sciences, Dr. H. S. Gour Central University, Sagar, Madhya Pradesh, India.

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http://dx.doi.org/10.1002/cbin.10549DOI Listing
February 2016
41 Reads
1.933 Impact Factor

Mitochondrial anomalies: driver to age associated degenerative human ailments.

Front Biosci (Landmark Ed) 2016 Jan 1;21:769-93. Epub 2016 Jan 1.

Associate Professor, Central University, Sagar (MP), India,

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January 2016
17 Reads
3 Citations

Amorphous solid dispersion technique for improved drug delivery: basics to clinical applications.

Drug Deliv Transl Res 2015 Dec;5(6):552-65

School of Biological Sciences, Dr. H. S. Gour Central University, Sagar, India.

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http://dx.doi.org/10.1007/s13346-015-0256-9DOI Listing
December 2015
32 Reads
1 Citation

Circulating nucleic acids damage DNA of healthy cells by integrating into their genomes.

J Biosci 2015 Mar;40(1):91-111

Translational Research Laboratory, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779614PMC
March 2015
53 Reads
12 Citations
2.064 Impact Factor

Solid dispersion in pharmaceutical drug development: from basics to clinical applications.

Curr Drug Deliv 2014 ;11(2):155-71

Department of Pharmaceutics, College of Pharmacy, IPS Academy, Indore (M.P.) India.

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January 2015
4 Reads
1 Citation
2.250 Impact Factor

Mitochondrial oxidative stress-induced epigenetic modifications in pancreatic epithelial cells.

Int J Toxicol 2014 Mar-Apr;33(2):116-29. Epub 2014 Feb 20.

Translational Research Lab, School of Biological Sciences, Dr Hari Singh Gour Central University, Sagar, Madhya Pradesh, India. Email:

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http://dx.doi.org/10.1177/1091581814524064DOI Listing
November 2014
31 Reads
5 Citations
1.233 Impact Factor

Stress induced premature senescence: a new culprit in ovarian tumorigenesis?

Indian J Med Res 2014 Nov;140 Suppl:S120-9

Division of Translational Research, Tata Memorial Centre, Advanced Centre for Treatment, Research & Education in Cancer (ACTREC), Navi Mumbai, India.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345742PMC
November 2014
8 Reads
2 Citations
1.661 Impact Factor

Nanoengineered strategies to optimize dendritic cells for gastrointestinal tumor immunotherapy: from biology to translational medicine.

Nanomedicine (Lond) 2014 Jul;9(14):2187-202

Translational Research Laboratory, School of Biological Sciences, Dr H. S. Gour Central University, Sagar, India.

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http://dx.doi.org/10.2217/nnm.14.115DOI Listing
July 2014
28 Reads
3 Citations
5.413 Impact Factor

Molecular detection of window phase hepatitis C virus infection in voluntary blood donors and health care workers in a cohort from central India.

Indian J Community Med 2014 Jan;39(1):51-2

Department of Research, Bhopal Memorial Hospital and Research Centre, Bhopal, India ; Division of Translational Research, Tata Memorial Centre, ACTREC, Navi Mumbai, Maharashtra, India.

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http://dx.doi.org/10.4103/0970-0218.126362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968585PMC
January 2014
9 Reads
1 Citation

Clinical presentation, etiology, and survival in adult acute encephalitis syndrome in rural Central India.

Clin Neurol Neurosurg 2013 Sep 1;115(9):1753-61. Epub 2013 May 1.

Department of Medicine, All India Institute of Medical Sciences, Bhopal, India.

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http://dx.doi.org/10.1016/j.clineuro.2013.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786210PMC
September 2013
23 Reads
2 Citations
1.250 Impact Factor

Transdermal immunization: biological framework and translational perspectives.

Expert Opin Drug Deliv 2013 Feb 21;10(2):183-200. Epub 2012 Dec 21.

Guru Ghasidas Central University, SLT Institute of Pharmaceutical Sciences, Department of Pharmaceutics, Bilaspur (CG) 495009, India.

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http://dx.doi.org/10.1517/17425247.2013.746660DOI Listing
February 2013
3 Reads
2 Citations
4.840 Impact Factor

Engineered dendritic cells for gastrointestinal tumor immunotherapy: opportunities in translational research.

J Drug Target 2013 Feb 15;21(2):126-36. Epub 2012 Oct 15.

Division of Translational Research, Tata Memorial Centre, ACTREC, Navi, Mumbai, India.

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http://dx.doi.org/10.3109/1061186X.2012.731069DOI Listing
February 2013
8 Reads
2 Citations

Engineering solid lipid nanoparticles for improved drug delivery: promises and challenges of translational research.

Drug Deliv Transl Res 2012 Aug;2(4):238-53

SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur, India,

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http://dx.doi.org/10.1007/s13346-012-0088-9DOI Listing
August 2012
14 Reads
5 Citations

Dendritic cell engineering for tumor immunotherapy: from biology to clinical translation.

Immunotherapy 2012 Jul;4(7):703-18

Division of Translational Research, Tata Memorial Centre, ACTREC, India.

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http://dx.doi.org/10.2217/imt.12.40DOI Listing
July 2012
5 Reads
7 Citations
2.440 Impact Factor

Nucleic acids in circulation: are they harmful to the host?

J Biosci 2012 Jun;37(2):301-12

Department of Translational Research, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Kharghar, Navi Mumbai 410 210, India.

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June 2012
37 Reads
16 Citations
2.064 Impact Factor

A pragmatic & translational approach of human biomonitoring to methyl isocyanate exposure in Bhopal.

Indian J Med Res 2012 Apr;135(4):479-84

Division of Translational Research, Tata Memorial Centre, ACTREC, Navi Mumbai, India.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385230PMC
April 2012
10 Reads
5 Citations
1.661 Impact Factor

Novel approach for quantification of hepatitis C virus in liver cirrhosis using real-time reverse transcriptase PCR.

J Gastrointest Surg 2012 Jan 3;16(1):142-6; discussion 146-7. Epub 2011 Nov 3.

Department of Surgical Gastroenterology, Bhopal Memorial Hospital & Research Center, Karond, Raisen Bypass Road, Bhopal, 462 038, Madhya Pradesh, India.

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http://dx.doi.org/10.1007/s11605-011-1750-0DOI Listing
January 2012
10 Reads
2.800 Impact Factor

In vitro and in vivo evaluation of the anticarcinogenic and cancer chemopreventive potential of a flavonoid-rich fraction from a traditional Indian herb Selaginella bryopteris.

Br J Nutr 2011 Oct 31;106(8):1154-68. Epub 2011 May 31.

Research Wing, Bhopal Memorial Hospital and Research Centre, Bhopal, India.

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http://dx.doi.org/10.1017/S0007114511001498DOI Listing
October 2011
93 Reads
7 Citations
3.453 Impact Factor

Molecular characterization of isocyanate-induced male germ-line genomic instability.

J Environ Pathol Toxicol Oncol 2010 ;29(3):213-34

Department of Research, Bhopal Memorial Hospital & Research Centre, Bhokal, India.

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March 2011
26 Reads
4 Citations
0.880 Impact Factor

Evaluation of cytotoxicity and anticarcinogenic potential of Mentha leaf extracts.

Int J Toxicol 2011 Mar 7;30(2):225-36. Epub 2011 Feb 7.

Bhopal Memorial Hospital & Research Centre, Bhopal, India.

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http://dx.doi.org/10.1177/1091581810390527DOI Listing
March 2011
83 Reads
4 Citations
1.233 Impact Factor

Molecular mechanisms of isocyanate induced oncogenic transformation in ovarian epithelial cells.

Reprod Toxicol 2010 Nov 8;30(3):377-86. Epub 2010 Jun 8.

Bhopal Memorial Hospital & Research Centre, Bhopal, India.

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http://dx.doi.org/10.1016/j.reprotox.2010.05.087DOI Listing
November 2010
18 Reads
5 Citations
3.230 Impact Factor

Status of inflammatory biomarkers in the population that survived the Bhopal gas tragedy: a study after two decades.

Ind Health 2010 ;48(2):204-8

Department of Research and Training, Bhopal Memorial Hospital & Research Centre, Bhopal, Madhya Pradesh, India.

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http://dx.doi.org/10.2486/indhealth.48.204DOI Listing
July 2010
26 Reads
6 Citations
1.045 Impact Factor

Molecular detection of Mycobacterium tuberculosis in formalin-fixed, paraffin-embedded tissues and biopsies of gastrointestinal specimens using real-time polymerase chain reaction system.

Turk J Gastroenterol 2010 Jun;21(2):129-34

Department of Research and Training, Bhopal Memorial Hospital and Research Centre, Bhopal, India.

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http://dx.doi.org/10.4318/tjg.2010.0070DOI Listing
June 2010
10 Reads
4 Citations
0.470 Impact Factor

Diagnosis of gastrointestinal tuberculosis: Using cytomorphological, microbiological, immunological and molecular techniques - A study from Central India.

Indian J Clin Biochem 2010 Apr 27;25(2):158-63. Epub 2010 May 27.

Department of Research, Bhopal Memorial Hospital & Research Centre, Bhopal, India ; Department of Research & Training, Bhopal Memorial Hospital & Research Centre, Bhopal, India.

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http://dx.doi.org/10.1007/s12291-010-0029-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3453110PMC
April 2010
11 Reads
1 Citation

Comparative evaluation of hepatitis B surface antigen-loaded elastic liposomes and ethosomes for human dendritic cell uptake and immune response.

Nanomedicine 2010 Feb 14;6(1):110-8. Epub 2009 May 14.

Department of Pharmaceutical Sciences, Dr. Hari Singh Gour University, Sagar, India.

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http://dx.doi.org/10.1016/j.nano.2009.04.003DOI Listing
February 2010
6 Reads
8 Citations
6.160 Impact Factor

Induction of genomic instability in cultured human colon epithelial cells following exposure to isocyanates.

Cell Biol Int 2009 Jun 17;33(6):675-83. Epub 2009 Apr 17.

Bhopal Memorial Hospital & Research Centre, Bhopal, India.

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http://dx.doi.org/10.1016/j.cellbi.2009.03.008DOI Listing
June 2009
10 Reads
3 Citations
1.933 Impact Factor

Analysis of cellular response to isocyanate using N-succinimidyl N-methylcarbamate exposure in cultured mammalian cells.

Environ Mol Mutagen 2009 May;50(4):328-36

Bhopal Memorial Hospital and Research Centre, Raisen Bypass Road, Bhopal-462 038, Madhya Pradesh, India.

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http://dx.doi.org/10.1002/em.20469DOI Listing
May 2009
23 Reads
5 Citations
2.630 Impact Factor

Isocyanates induces DNA damage, apoptosis, oxidative stress, and inflammation in cultured human lymphocytes.

J Biochem Mol Toxicol 2008 Nov-Dec;22(6):429-40

Bhopal Memorial Hospital & Research Centre, Raisen Bypass Road, Bhopal 462 038, India. pkm

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http://dx.doi.org/10.1002/jbt.20260DOI Listing
April 2009
20 Reads
8 Citations
1.925 Impact Factor

Systemic and mucosal immune response induced by transcutaneous immunization using Hepatitis B surface antigen-loaded modified liposomes.

Eur J Pharm Sci 2008 Apr 12;33(4-5):424-33. Epub 2008 Feb 12.

Pharmaceutics Research Laboratory, Department of Pharmaceutical Sciences, Dr. Hari Singh Gour University, Sagar 470003, India.

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http://dx.doi.org/10.1016/j.ejps.2008.01.015DOI Listing
April 2008
12 Reads
9 Citations
3.350 Impact Factor

Evaluation of uptake and generation of immune response by murine dendritic cells pulsed with hepatitis B surface antigen-loaded elastic liposomes.

Vaccine 2007 Sep 17;25(39-40):6939-44. Epub 2007 Jul 17.

Department of Pharmaceutical Sciences, Dr. H.S. Gour University, Sagar, India.

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http://dx.doi.org/10.1016/j.vaccine.2007.06.055DOI Listing
September 2007
23 Reads
1 Citation
3.624 Impact Factor

Top co-authors

Arpit Bhargava
Arpit Bhargava

Tata Memorial Centre, Bhopal Memorial Hospital & Research Centre

21
Neha Bunkar
Neha Bunkar

Translational Research Lab

10
Gorantla Venkata Raghuram
Gorantla Venkata Raghuram

Bhopal Memorial Hospital & Research Centre

9
Neelam Pathak
Neelam Pathak

Bhopal Memorial Hospital & Research Centre

8
Kewal Krishan Maudar
Kewal Krishan Maudar

Bhopal Memorial Hospital & Research Center

6
Rajnarayan Tiwari
Rajnarayan Tiwari

National Institute of Occupational Health

5
Smita Banerjee
Smita Banerjee

Memorial Sloan-Kettering Cancer Center

4