Peter W Jurutka

Peter W Jurutka

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Peter W Jurutka

Peter W Jurutka

Publications by authors named "Peter W Jurutka"

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16α-Hydroxytrametenolic Acid from Improves Intestinal Barrier Function Through the Glucocorticoid Receptor-Mediated PI3K/Akt/NF-κB Pathway.

J Agric Food Chem 2019 Oct 23;67(39):10871-10879. Epub 2019 Sep 23.

School of Mathematical and Natural Sciences , Arizona State University , Tempe , Arizona 85306 , United States.

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http://dx.doi.org/10.1021/acs.jafc.9b04613DOI Listing
October 2019

Triterpenes from Poria cocos are revealed as potential retinoid X receptor selective agonists based on cell and in silico evidence.

Chem Biol Drug Des 2019 Aug 24. Epub 2019 Aug 24.

Department of Food Quality and Safety, School of Engineering, China Pharmaceutical University, Nanjing, Jiangsu, 211198, China.

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http://dx.doi.org/10.1111/cbdd.13610DOI Listing
August 2019

Testing Novel Pyrimidinyl Rexinoids: A New Paradigm for Evaluating Rexinoids for Cancer Prevention.

Cancer Prev Res (Phila) 2019 Apr 13;12(4):211-224. Epub 2019 Feb 13.

Department of Pharmacology and Toxicology, Michigan State University, East Lansing, Michigan.

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http://dx.doi.org/10.1158/1940-6207.CAPR-18-0317DOI Listing
April 2019

Methods to Assess Activity and Potency of Rexinoids Using Rapid Luciferase-Based Assays: A Case Study with NEt-TMN.

Methods Mol Biol 2019 ;2019:95-108

School of Mathematical and Natural Sciences, New College of Interdisciplinary Arts and Sciences, Arizona State University, Glendale, AZ, USA.

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http://dx.doi.org/10.1007/978-1-4939-9585-1_7DOI Listing
January 2019

Methods to Generate an Array of Novel Rexinoids by SAR on a Potent Retinoid X Receptor Agonist: A Case Study with NEt-TMN.

Methods Mol Biol 2019 ;2019:109-121

School of Mathematical and Natural Sciences, New College of Interdisciplinary Arts and Sciences, Arizona State University, Glendale, AZ, USA.

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http://dx.doi.org/10.1007/978-1-4939-9585-1_8DOI Listing
January 2019

Dataset on the response of Hut78 cells to novel rexinoids.

Data Brief 2018 Oct 12;20:1797-1803. Epub 2018 Sep 12.

School of Mathematical and Natural Sciences, Arizona State University, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S23523409183108
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http://dx.doi.org/10.1016/j.dib.2018.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169431PMC
October 2018

SIRT1 enzymatically potentiates 1,25-dihydroxyvitamin D signaling via vitamin D receptor deacetylation.

J Steroid Biochem Mol Biol 2017 09 19;172:117-129. Epub 2017 Jun 19.

Arizona State University, School of Mathematical and Natural Sciences, 4701 W. Thunderbird Road Glendale, AZ 85306, USA; University of Arizona College of Medicine-Phoenix, Department of Basic Medical Sciences, 425 N. 5th Street Phoenix, AZ 85004, USA; University of Arizona Cancer Center,1501 N. Campbell Avenue, Tucson, AZ 85719, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2017.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584940PMC
September 2017

Total and Free Circulating Vitamin D and Vitamin D-Binding Protein in Relation to Colorectal Cancer Risk in a Prospective Study of African Americans.

Cancer Epidemiol Biomarkers Prev 2017 08 8;26(8):1242-1247. Epub 2017 May 8.

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee.

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http://dx.doi.org/10.1158/1055-9965.EPI-17-0133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540758PMC
August 2017

Retinoid X Receptor Selective Agonists and their Synthetic Methods.

Curr Top Med Chem 2017 ;17(6):742-767

School of Mathematical and Natural Sciences, Arizona State University, 4701 W Thunderbird Road, Glendale, AZ, United States.

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http://dx.doi.org/10.2174/1568026616666160617091559DOI Listing
February 2017

EDITORIAL (Thematic Issue : Rexinoids).

Curr Top Med Chem 2017 ;17(6):629-630

School of Mathematical and Natural Sciences Arizona State University Glendale, AZ. United States.

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http://dx.doi.org/10.2174/156802661706170111200835DOI Listing
February 2017

1,25-Dihydroxyvitamin D and Klotho: A Tale of Two Renal Hormones Coming of Age.

Vitam Horm 2016 13;100:165-230. Epub 2016 Jan 13.

Department of Basic Medical Sciences, University of Arizona College of Medicine, Phoenix, Arizona, USA; School of Mathematical and Natural Sciences, Arizona State University, Glendale, Arizona, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00836729150006
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http://dx.doi.org/10.1016/bs.vh.2015.11.005DOI Listing
January 2017

CYP24A1 and CYP27B1 Polymorphisms, Concentrations of Vitamin D Metabolites, and Odds of Colorectal Adenoma Recurrence.

Nutr Cancer 2015 4;67(7):1131-41. Epub 2015 Aug 4.

e Mel and Enid Zuckerman College of Public Health, University of Arizona , Tucson , Arizona , USA and University of Arizona Cancer Center , Tucson , Arizona , USA.

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http://dx.doi.org/10.1080/01635581.2015.1068818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589517PMC
July 2016

Association between Circulating Vitamin D Metabolites and Fecal Bile Acid Concentrations.

Cancer Prev Res (Phila) 2016 Jul 2;9(7):589-97. Epub 2016 May 2.

University of Arizona Cancer Center, Tucson, Arizona. Department of Basic Medical Sciences, University of Arizona College of Medicine, Phoenix, Arizona. School of Mathematical and Natural Sciences, Arizona State University, Phoenix, Arizona.

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http://dx.doi.org/10.1158/1940-6207.CAPR-16-0033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993194PMC
July 2016

Physical activity, sedentary behavior, and vitamin D metabolites.

Bone 2016 Feb 24;83:248-255. Epub 2015 Nov 24.

Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ; University of Arizona Cancer Center, University of Arizona, Tucson, AZ.

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http://dx.doi.org/10.1016/j.bone.2015.11.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795004PMC
February 2016

Vitamin D and Colorectal, Breast, and Prostate Cancers: A Review of the Epidemiological Evidence.

J Cancer 2016 5;7(3):232-40. Epub 2016 Jan 5.

University of Arizona Cancer Center, Tucson, Arizona (ETJ); Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona (ETJ, LNK); Department of Nutritional Sciences, University of Arizona, Tucson, Arizona (ETJ, AGK); School of Mathematical and Natural Sciences, Arizona State University, Phoenix, Arizona (PWJ); Department of Basic Medical Sciences, The University of Arizona, College of Medicine, Phoenix, AZ (PWJ).

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http://www.jcancer.org/v07p0232.pdf
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http://www.jcancer.org/v07p0232.htm
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http://dx.doi.org/10.7150/jca.13403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747876PMC
February 2016

1,25-Dihydroxyvitamin D regulates expression of the tryptophan hydroxylase 2 and leptin genes: implication for behavioral influences of vitamin D.

FASEB J 2015 Sep 12;29(9):4023-35. Epub 2015 Jun 12.

*Department of Basic Medical Sciences, University of Arizona College of Medicine, Phoenix, Arizona, USA; School of Mathematical and Natural Sciences, Arizona State University, Phoenix, Arizona, USA; and Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA

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http://www.fasebj.org/content/early/2015/06/12/fj.14-269811.
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http://www.fasebj.org/cgi/doi/10.1096/fj.14-269811
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http://dx.doi.org/10.1096/fj.14-269811DOI Listing
September 2015

FGF23 gene regulation by 1,25-dihydroxyvitamin D: opposing effects in adipocytes and osteocytes.

J Endocrinol 2015 Sep 6;226(3):155-66. Epub 2015 Jul 6.

Department of Basic Medical SciencesUniversity of Arizona College of Medicine, 425 N. Fifth Street, Phoenix, Arizona 85004, USASchool of Mathematical and Natural SciencesArizona State University, 4701 W. Thunderbird Road, Phoenix, Arizona 85306, USA Department of Basic Medical SciencesUniversity of Arizona College of Medicine, 425 N. Fifth Street, Phoenix, Arizona 85004, USASchool of Mathematical and Natural SciencesArizona State University, 4701 W. Thunderbird Road, Phoenix, Arizona 85306, USA

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http://joe.endocrinology-journals.org/content/226/3/155.full
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http://joe.endocrinology-journals.org/content/early/2015/07/
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http://joe.endocrinology-journals.org/lookup/doi/10.1530/JOE
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http://dx.doi.org/10.1530/JOE-15-0225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560246PMC
September 2015

Distinct functional modes of SUMOylation for retinoid X receptor alpha.

Biochem Biophys Res Commun 2015 Aug 23;464(1):195-200. Epub 2015 Jun 23.

School of Biomedical Sciences, University of Ulster, Coleraine, BT52 1SA, Northern Ireland, UK. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.06.115DOI Listing
August 2015

Resveratrol potentiates vitamin D and nuclear receptor signaling.

J Cell Biochem 2015 Jun;116(6):1130-43

School of Mathematical and Natural Sciences, Arizona State University, Glendale, Arizona, 85306.

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http://dx.doi.org/10.1002/jcb.25070DOI Listing
June 2015

Concentrations of the vitamin D metabolite 1,25(OH)2D and odds of metabolic syndrome and its components.

Metabolism 2015 Mar 29;64(3):447-59. Epub 2014 Nov 29.

University of Arizona Cancer Center, 1515N. Campbell Avenue, Tucson, AZ 85724-5024, USA; Mel and Enid Zuckerman College of Public Health, 1295N. Martin Ave., Tucson, AZ, 85724, USA. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2014.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312532PMC
March 2015

Analysis of differential secondary effects of novel rexinoids: select rexinoid X receptor ligands demonstrate differentiated side effect profiles.

Pharmacol Res Perspect 2015 Mar 16;3(2):e00122. Epub 2015 Mar 16.

School of Mathematical and Natural Sciences, New College of Interdisciplinary Arts and Sciences, Arizona State University 4701 W Thunderbird Rd, Glendale, Arizona, 85306.

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http://dx.doi.org/10.1002/prp2.122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448986PMC
March 2015

Associations between circulating 1,25(OH)₂D concentration and odds of metachronous colorectal adenoma.

Cancer Causes Control 2014 Jul 16;25(7):809-17. Epub 2014 Apr 16.

University of Arizona Cancer Center, 1515 N. Campbell Ave, Tucson, AZ, 85724-5024, USA,

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http://dx.doi.org/10.1007/s10552-014-0382-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537068PMC
July 2014

Vitamin D receptor-mediated control of Soggy, Wise, and Hairless gene expression in keratinocytes.

J Endocrinol 2014 Feb 8;220(2):165-78. Epub 2014 Jan 8.

Department of Basic Medical Sciences, University of Arizona College of Medicine, 425 North 5th Street, Phoenix, Arizona 85004-2157, USA School of Mathematical and Natural Sciences, Arizona State University, Phoenix, Arizona 85306, USA.

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http://dx.doi.org/10.1530/JOE-13-0212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947288PMC
February 2014

Regulation of late cornified envelope genes relevant to psoriasis risk by plant-derived cyanidin.

Biochem Biophys Res Commun 2014 Jan 3;443(4):1275-9. Epub 2014 Jan 3.

Department of Basic Medical Sciences, University of Arizona College of Medicine - Phoenix, Phoenix, AZ 85004, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2013.12.128DOI Listing
January 2014

Association between circulating concentrations of 25(OH)D and colorectal adenoma: a pooled analysis.

Int J Cancer 2013 Dec 11;133(12):2980-8. Epub 2013 Jul 11.

University of Arizona Cancer Center, University of Arizona, Tucson, Arizona; Division of Epidemiology, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona.

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http://dx.doi.org/10.1002/ijc.28316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797158PMC
December 2013

Control of late cornified envelope genes relevant to psoriasis risk: upregulation by 1,25-dihydroxyvitamin D3 and plant-derived delphinidin.

Arch Dermatol Res 2013 Dec 10;305(10):867-78. Epub 2013 Jul 10.

Department of Basic Medical Sciences, University of Arizona College of Medicine, Phoenix, 425 N Fifth Street, Phoenix, AZ, 85004-2157, USA.

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http://dx.doi.org/10.1007/s00403-013-1390-1DOI Listing
December 2013

Molecular mechanisms of vitamin D action.

Calcif Tissue Int 2013 Feb 11;92(2):77-98. Epub 2012 Jul 11.

Department of Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, 425 North 5th Street, Phoenix, AZ 85004-2157, USA.

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http://link.springer.com/content/pdf/10.1007/s00223-012-9619
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http://link.springer.com/10.1007/s00223-012-9619-0
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http://dx.doi.org/10.1007/s00223-012-9619-0DOI Listing
February 2013

Synthesis and biological evaluation of halogenated curcumin analogs as potential nuclear receptor selective agonists.

Bioorg Med Chem 2013 Feb 5;21(3):693-702. Epub 2012 Dec 5.

School of Mathematical and Natural Sciences, New College of Interdisciplinary Arts and Sciences, Arizona State University, 4701 W. Thunderbird Road, Glendale, AZ 85306, United States.

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http://dx.doi.org/10.1016/j.bmc.2012.11.033DOI Listing
February 2013

Discovery of novel vitamin D receptor interacting proteins that modulate 1,25-dihydroxyvitamin D3 signaling.

J Steroid Biochem Mol Biol 2012 Oct 14;132(1-2):147-59. Epub 2012 May 14.

Division of Mathematical and Natural Sciences, Arizona State University, Glendale, AZ 85306, United States.

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http://dx.doi.org/10.1016/j.jsbmb.2012.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408799PMC
October 2012

The role of vitamin D in the FGF23, klotho, and phosphate bone-kidney endocrine axis.

Rev Endocr Metab Disord 2012 Mar;13(1):57-69

Department of Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, Phoenix, AZ 85004, USA.

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http://link.springer.com/10.1007/s11154-011-9199-8
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http://dx.doi.org/10.1007/s11154-011-9199-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288475PMC
March 2012

Vitamin D receptor controls expression of the anti-aging klotho gene in mouse and human renal cells.

Biochem Biophys Res Commun 2011 Oct 1;414(3):557-62. Epub 2011 Oct 1.

Department of Basic Medical Sciences, University of Arizona College of Medicine - Phoenix, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1016/j.bbrc.2011.09.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209523PMC
October 2011

Vitamin D receptor (VDR)-mediated actions of 1α,25(OH)₂vitamin D₃: genomic and non-genomic mechanisms.

Best Pract Res Clin Endocrinol Metab 2011 Aug;25(4):543-59

Department of Basic Medical Sciences, University of Arizona College of Medicine, Phoenix, AZ 85004, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S1521690X110006
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http://dx.doi.org/10.1016/j.beem.2011.05.010DOI Listing
August 2011

Vitamin D: marker or mechanism of action?

Cancer Epidemiol Biomarkers Prev 2011 Apr;20(4):585-90

Arizona Cancer Center, University of Arizona, P.O. Box 245024, 1515 N Campbell Ave, Tucson, AZ 85724-5024, USA.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-1
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http://dx.doi.org/10.1158/1055-9965.EPI-10-1257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074255PMC
April 2011

Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention.

J Nutr Biochem 2010 Dec 12;21(12):1153-61. Epub 2010 Feb 12.

Department of Biochemistry and Molecular Biophysics, College of Medicine, The University of Arizona, Tucson, AZ 85724, USA.

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http://dx.doi.org/10.1016/j.jnutbio.2009.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891903PMC
December 2010

The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the "Fountain of Youth" to mediate healthful aging.

J Steroid Biochem Mol Biol 2010 Jul 20;121(1-2):88-97. Epub 2010 Mar 20.

Department of Basic Medical Sciences, The University of Arizona, College of Medicine-Phoenix in partnership with Arizona State University, Phoenix, AZ 85004-2157, United States.

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http://dx.doi.org/10.1016/j.jsbmb.2010.03.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906618PMC
July 2010

Genetic polymorphisms in vitamin D receptor VDR/RXRA influence the likelihood of colon adenoma recurrence.

Cancer Res 2010 Feb 9;70(4):1496-504. Epub 2010 Feb 9.

Arizona Cancer Center, University of Arizona and Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona 85724-5024, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019606PMC
February 2010

Vitamin D, calcium, and colorectal neoplasia: new insights on mechanisms of action.

Cancer Prev Res (Phila) 2009 Mar 3;2(3):197-9. Epub 2009 Mar 3.

Arizona Cancer Center, University of Arizona, P.O. Box 245024, Tucson, Arizona 85724-5024, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-09-0019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078623PMC
March 2009

Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention.

Nutr Rev 2008 Oct;66(10 Suppl 2):S98-112

The Department of Basic Medical Sciences, University of Arizona College of Medicine-Phoenix, in Partnership with Arizona State University, Phoenix, Arizona 85004-2157, USA.

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https://academic.oup.com/nutritionreviews/article-lookup/doi
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http://dx.doi.org/10.1111/j.1753-4887.2008.00093.xDOI Listing
October 2008

Vitamin D receptor: key roles in bone mineral pathophysiology, molecular mechanism of action, and novel nutritional ligands.

J Bone Miner Res 2007 Dec;22 Suppl 2:V2-10

Department of Integrated Natural Sciences, Arizona State University at the West Campus, Glendale, Arizona, USA.

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http://dx.doi.org/10.1359/jbmr.07s216DOI Listing
December 2007

1,25-dihydroxyvitamin D3 down-regulation of PHEX gene expression is mediated by apparent repression of a 110 kDa transfactor that binds to a polyadenine element in the promoter.

J Biol Chem 2004 Nov 25;279(45):46406-14. Epub 2004 Aug 25.

Department of Pediatrics, College of Medicine, Steele Memorial Children's Research Center, University of Arizona, Tucson, Arizona 85724, USA.

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http://dx.doi.org/10.1074/jbc.M404278200DOI Listing
November 2004

Phosphorylation of human vitamin D receptor serine-182 by PKA suppresses 1,25(OH)2D3-dependent transactivation.

Biochem Biophys Res Commun 2004 Nov;324(2):801-9

Department of Biochemistry and Molecular Biophysics, College of Medicine, University of Arizona, Tucson, AZ 85724, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0402186
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http://dx.doi.org/10.1016/j.bbrc.2004.09.139DOI Listing
November 2004

Physical and functional interaction between the vitamin D receptor and hairless corepressor, two proteins required for hair cycling.

J Biol Chem 2003 Oct 7;278(40):38665-74. Epub 2003 Jul 7.

Department of Biochemistry and Molecular Biophysics, University of Arizona College of Medicine, Tucson, Arizona 85724, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M304886200
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http://dx.doi.org/10.1074/jbc.M304886200DOI Listing
October 2003

Liganded VDR induces CYP3A4 in small intestinal and colon cancer cells via DR3 and ER6 vitamin D responsive elements.

Biochem Biophys Res Commun 2002 Dec;299(5):730-8

Department of Biochemistry and Molecular Biophysics, College of Medicine, University of Arizona, Tucson, AZ 85724, USA.

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http://dx.doi.org/10.1016/s0006-291x(02)02742-0DOI Listing
December 2002

Isolation of baculovirus-expressed human vitamin D receptor: DNA responsive element interactions and phosphorylation of the purified receptor.

J Cell Biochem 2002 ;85(2):435-57

Department of Biochemistry and Molecular Biophysics, College of Medicine, University of Arizona, Tucson, Arizona 85724, USA.

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July 2002