Patrick Schrauwen

Patrick Schrauwen

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Patrick Schrauwen

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Effects of a whole diet approach on metabolic flexibility, insulin sensitivity and postprandial glucose responses in overweight and obese adults - A randomized controlled trial.

Clin Nutr 2019 Dec 17. Epub 2019 Dec 17.

Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, Maastricht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2019.12.010DOI Listing
December 2019

Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: A randomised controlled trial.

EBioMedicine 2019 Nov 31;49:318-330. Epub 2019 Oct 31.

Department of Radiology and Nuclear Medicine, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, 6200 MD Maastricht, the Netherlands; Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, 6200 MD Maastricht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945245PMC
November 2019

TSH suppression aggravates arterial inflammation - an F-FDG PET study in thyroid carcinoma patients.

Eur J Nucl Med Mol Imaging 2019 Jul 11;46(7):1428-1438. Epub 2019 Mar 11.

Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre (MUMC+), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s00259-019-04292-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533218PMC
July 2019

In vitro effects of sitosterol and sitostanol on mitochondrial respiration in human brown adipocytes, myotubes and hepatocytes.

Eur J Nutr 2019 Jul 17. Epub 2019 Jul 17.

Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, 6200 MD, The Netherlands.

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http://dx.doi.org/10.1007/s00394-019-02052-yDOI Listing
July 2019

NAD metabolism as a target for metabolic health: have we found the silver bullet?

Diabetologia 2019 06 16;62(6):888-899. Epub 2019 Feb 16.

Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University, Universiteitssingel 50, P.O. Box 616, 6200 MD, Maastricht, the Netherlands.

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http://dx.doi.org/10.1007/s00125-019-4831-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509089PMC
June 2019

Underpowered or negative? A crucial distinction. Reply to Dollerup OL, Treebak JT, Jessen N [letter].

Diabetologia 2019 06 13;62(6):1096. Epub 2019 Apr 13.

Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University, Universiteitssingel 50, P.O. Box 616, 6200 MD, Maastricht, the Netherlands.

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http://dx.doi.org/10.1007/s00125-019-4868-3DOI Listing
June 2019

Circadian clocks and insulin resistance.

Nat Rev Endocrinol 2019 02;15(2):75-89

Department of Endocrinology and Metabolism, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.

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http://www.nature.com/articles/s41574-018-0122-1
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http://dx.doi.org/10.1038/s41574-018-0122-1DOI Listing
February 2019

Distinct lipid droplet characteristics and distribution unmask the apparent contradiction of the athlete's paradox.

Mol Metab 2018 11 18;17:71-81. Epub 2018 Aug 18.

Department of Nutrition and Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2018.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197504PMC
November 2018

Exercise training-induced effects on the abdominal subcutaneous adipose tissue phenotype in humans with obesity.

J Appl Physiol (1985) 2018 11 13;125(5):1585-1593. Epub 2018 Sep 13.

Department of Human Biology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht , The Netherlands.

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http://dx.doi.org/10.1152/japplphysiol.00496.2018DOI Listing
November 2018

Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle.

Proc Natl Acad Sci U S A 2018 07 9;115(30):7789-7794. Epub 2018 Jul 9.

Department of Nutrition and Movement Sciences, School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, 6200 MD Maastricht, The Netherlands;

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http://dx.doi.org/10.1073/pnas.1722295115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065021PMC
July 2018

Circadian rhythms in mitochondrial respiration.

J Mol Endocrinol 2018 04 29;60(3):R115-R130. Epub 2018 Jan 29.

Department of Clinical Chemistry, Laboratory of Endocrinology, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1530/JME-17-0196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854864PMC
April 2018

The Peroxisome Proliferator-Activated Receptor α is dispensable for cold-induced adipose tissue browning in mice.

Mol Metab 2018 04 9;10:39-54. Epub 2018 Feb 9.

Nutrition, Metabolism and Genomics Group, Division of Human Nutrition and Health, Wageningen University, Stippeneng 4, 6708 WE Wageningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2018.01.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985232PMC
April 2018

Dissociation of intramyocellular lipid storage and insulin resistance in trained athletes and type 2 diabetes patients; involvement of perilipin 5?

J Physiol 2018 03 23;596(5):857-868. Epub 2017 Nov 23.

Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands.

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http://doi.wiley.com/10.1113/JP275182
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http://dx.doi.org/10.1113/JP275182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830434PMC
March 2018

Exercise training reduces intrahepatic lipid content in people with and people without nonalcoholic fatty liver.

Am J Physiol Endocrinol Metab 2018 02 7;314(2):E165-E173. Epub 2017 Nov 7.

NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center , Maastricht , The Netherlands.

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http://dx.doi.org/10.1152/ajpendo.00266.2017DOI Listing
February 2018

Genetic Markers of Brown Adipose Tissue Identity and In Vitro Brown Adipose Tissue Activity in Humans.

Obesity (Silver Spring) 2018 01 27;26(1):135-140. Epub 2017 Nov 27.

Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1002/oby.22062DOI Listing
January 2018

An unbiased silencing screen in muscle cells identifies miR-320a, miR-150, miR-196b, and miR-34c as regulators of skeletal muscle mitochondrial metabolism.

Mol Metab 2017 11 31;6(11):1429-1442. Epub 2017 Aug 31.

Department of Human Biology and Human Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, 6200MD, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2017.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681243PMC
November 2017

Intramyocellular lipid droplets and insulin sensitivity, the human perspective.

Biochim Biophys Acta Mol Cell Biol Lipids 2017 Oct 22;1862(10 Pt B):1242-1249. Epub 2017 Jul 22.

Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, 6200MD Maastricht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2017.07.010DOI Listing
October 2017

Response to Comment on Timmers et al. Resveratrol as Add-on Therapy in Subjects With Well-Controlled Type 2 Diabetes: A Randomized Controlled Trial. Diabetes Care 2016;39:2211-2217.

Diabetes Care 2017 09;40(9):e134

Department of Human Biology and Human Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands

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http://dx.doi.org/10.2337/dci17-0019DOI Listing
September 2017

Metabolic disturbances of non-alcoholic fatty liver resemble the alterations typical for type 2 diabetes.

Clin Sci (Lond) 2017 Aug 7;131(15):1905-1917. Epub 2017 Jul 7.

NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands

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http://dx.doi.org/10.1042/CS20170261DOI Listing
August 2017

Liver fat: a relevant target for dietary intervention? Summary of a Unilever workshop.

J Nutr Sci 2017 8;6:e15. Epub 2017 May 8.

Department of Human Biology, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1017/jns.2017.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468740PMC
May 2017

Brown adipose tissue: The magic bullet?

Obesity (Silver Spring) 2017 03 7;25(3):499. Epub 2017 Feb 7.

Department of Human Biology and Human Movement Sciences, NUTRIM school for Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1002/oby.21749DOI Listing
March 2017

Longitudinal relaxation time editing for acetylcarnitine detection with H-MRS.

Magn Reson Med 2017 02 17;77(2):505-510. Epub 2016 Feb 17.

Department of Radiology, NUTRIM school for Nutrition and Translational Research in Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1002/mrm.26149DOI Listing
February 2017

Resveratrol as Add-on Therapy in Subjects With Well-Controlled Type 2 Diabetes: A Randomized Controlled Trial.

Diabetes Care 2016 Dec 6;39(12):2211-2217. Epub 2016 Oct 6.

Department of Human Biology and Human Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands

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http://dx.doi.org/10.2337/dc16-0499DOI Listing
December 2016

Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus.

Nat Rev Endocrinol 2016 11 22;12(11):633-645. Epub 2016 Jul 22.

Department of Human Biology and Human Movement Sciences, Maastricht University Medical Center, Universiteitsingel 50, 6229 ER, Maastricht, Netherlands.

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http://dx.doi.org/10.1038/nrendo.2016.104DOI Listing
November 2016

Combatting type 2 diabetes by turning up the heat.

Diabetologia 2016 11 3;59(11):2269-2279. Epub 2016 Sep 3.

Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, P.O. BOX 616, 6200MD, Maastricht, the Netherlands.

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http://dx.doi.org/10.1007/s00125-016-4068-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506100PMC
November 2016

Effects of exercise training on intrahepatic lipid content in humans.

Diabetologia 2016 10 8;59(10):2068-79. Epub 2016 Jul 8.

NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center +, Maastricht, the Netherlands.

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http://dx.doi.org/10.1007/s00125-016-4037-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016557PMC
October 2016

Synchronized human skeletal myotubes of lean, obese and type 2 diabetic patients maintain circadian oscillation of clock genes.

Sci Rep 2016 10 19;6:35047. Epub 2016 Oct 19.

Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1038/srep35047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069469PMC
October 2016

Demonstration of a day-night rhythm in human skeletal muscle oxidative capacity.

Mol Metab 2016 Aug 1;5(8):635-645. Epub 2016 Jul 1.

Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, PO Box 616, 6200 MD Maastricht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2016.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021670PMC
August 2016

Combined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial.

Am J Clin Nutr 2016 Jul 18;104(1):215-27. Epub 2016 May 18.

Department of Human Biology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, Netherlands;

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http://dx.doi.org/10.3945/ajcn.115.122937DOI Listing
July 2016

Mitochondrial dynamics, quality control and miRNA regulation in skeletal muscle: implications for obesity and related metabolic disease.

Clin Sci (Lond) 2016 06;130(11):843-52

Department of Human Biology and Human Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, PO Box 616, 6200 MD Maastricht, the Netherlands

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http://clinsci.org/cgi/doi/10.1042/CS20150780
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http://dx.doi.org/10.1042/CS20150780DOI Listing
June 2016

Short-term Cold Acclimation Recruits Brown Adipose Tissue in Obese Humans.

Diabetes 2016 05 30;65(5):1179-89. Epub 2015 Dec 30.

Departments of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, the Netherlands

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http://dx.doi.org/10.2337/db15-1372DOI Listing
May 2016

Decoration of intramyocellular lipid droplets with PLIN5 modulates fasting-induced insulin resistance and lipotoxicity in humans.

Diabetologia 2016 May 10;59(5):1040-8. Epub 2016 Feb 10.

Department of Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, 6200MD, Maastricht, the Netherlands.

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http://link.springer.com/10.1007/s00125-016-3865-z
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http://dx.doi.org/10.1007/s00125-016-3865-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826431PMC
May 2016

ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity.

Diabetologia 2016 May 17;59(5):1030-9. Epub 2016 Feb 17.

Department of Human Biology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, P. O. Box 616, 6200MD, Maastricht, the Netherlands.

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http://dx.doi.org/10.1007/s00125-016-3885-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826430PMC
May 2016

A genistein-enriched diet neither improves skeletal muscle oxidative capacity nor prevents the transition towards advanced insulin resistance in ZDF rats.

Sci Rep 2016 Mar 14;6:22854. Epub 2016 Mar 14.

Department of Human Movement Sciences, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1038/srep22854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789602PMC
March 2016

Mitochondrial Function and Diabetes: Consequences for Skeletal and Cardiac Muscle Metabolism.

Antioxid Redox Signal 2016 Jan 28;24(1):39-51. Epub 2015 Apr 28.

2 Department of Human Biology, Maastricht University Medical Center , Maastricht, The Netherlands .

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http://www.liebertpub.com/doi/10.1089/ars.2015.6291
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http://dx.doi.org/10.1089/ars.2015.6291DOI Listing
January 2016

The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity.

Cell Metab 2015 Sep 30;22(3):418-26. Epub 2015 Jul 30.

Department of Human Biology and Human Movement Sciences, NUTRIM, School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht 6200 MD, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.07.002DOI Listing
September 2015

The future of brown adipose tissues in the treatment of type 2 diabetes.

Diabetologia 2015 Aug 9;58(8):1704-7. Epub 2015 May 9.

Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, PO Box 616, 6200MD, Maastricht, the Netherlands,

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http://dx.doi.org/10.1007/s00125-015-3611-yDOI Listing
August 2015

Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus.

Nat Med 2015 Aug 6;21(8):863-5. Epub 2015 Jul 6.

Department of Human Biology, School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, the Netherlands.

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http://dx.doi.org/10.1038/nm.3891DOI Listing
August 2015

Carnitine Acetyltransferase Mitigates Metabolic Inertia and Muscle Fatigue during Exercise.

Cell Metab 2015 Jul;22(1):65-76

Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27704, USA; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University, Durham, NC 27704, USA; Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition, Duke University, Durham, NC 27704, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754082PMC
July 2015

Resveratrol and obesity: Can resveratrol relieve metabolic disturbances?

Biochim Biophys Acta 2015 Jun 18;1852(6):1137-44. Epub 2014 Nov 18.

Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center, 6200MD Maastricht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2014.11.012DOI Listing
June 2015

Resveratrol: Challenges in translating pre-clinical findings to improved patient outcomes.

Biochim Biophys Acta 2015 Jun 18;1852(6):1069-70. Epub 2015 Feb 18.

Department of Human Biology and Human Movement Sciences, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, 6200 MD Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.bbadis.2015.02.002DOI Listing
June 2015

Serum FGF21 levels are associated with brown adipose tissue activity in humans.

Sci Rep 2015 May 18;5:10275. Epub 2015 May 18.

Department of Human Biology, NUTRIM School for Nutrition and Translational Research in Metabolism,Maastricht University Medical Centre+(MUMC+), Maastricht, the Netherlands.

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http://dx.doi.org/10.1038/srep10275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434994PMC
May 2015

Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans.

Diabetes 2015 Apr 28;64(4):1193-201. Epub 2014 Oct 28.

Department of Human Biology, Maastricht University Medical Center, Maastricht, the Netherlands School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center, Maastricht, the Netherlands

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http://dx.doi.org/10.2337/db14-0667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375076PMC
April 2015

Perilipin 5 mediated lipid droplet remodelling revealed by coherent Raman imaging.

Integr Biol (Camb) 2015 Apr;7(4):467-76

Department of Molecular Spectroscopy, Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany.

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http://dx.doi.org/10.1039/c4ib00271gDOI Listing
April 2015

Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance.

Diabetologia 2015 Mar 13;58(3):586-95. Epub 2014 Dec 13.

Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre+ (MUMC+), P.O. Box 616, 6200 MD, Maastricht, the Netherlands.

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http://dx.doi.org/10.1007/s00125-014-3465-8DOI Listing
March 2015

Diet and glycaemia: the markers and their meaning. A report of the Unilever Nutrition Workshop.

Br J Nutr 2015 Jan 11;113(2):239-48. Epub 2014 Dec 11.

Department of Endocrinology,Diabetes and Nutrition, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin,Berlin,Germany.

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http://dx.doi.org/10.1017/S0007114514003547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302387PMC
January 2015

Proton magnetic resonance spectroscopy reveals increased hepatic lipid content after a single high-fat meal with no additional modulation by added protein.

Am J Clin Nutr 2015 Jan 5;101(1):65-71. Epub 2014 Nov 5.

From the Departments of Radiology (LL, CIN, JEW, and VBS-H), Human Biology (LL, PS, and VBS-H), and Human Movement Sciences (CIN and MKCH), NUTRIM, Maastricht University Medical Center, Maastricht, The Netherlands, and Top Institute Food and Nutrition (LL, CIN, PS, and VBS-H), Wageningen, The Netherlands.

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https://academic.oup.com/ajcn/article/101/1/65/4564329
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http://dx.doi.org/10.3945/ajcn.114.094730DOI Listing
January 2015

Impaired skeletal muscle mitochondrial function in morbidly obese patients is normalized one year after bariatric surgery.

Surg Obes Relat Dis 2013 Nov-Dec;9(6):936-41. Epub 2013 Apr 18.

Department of Surgery, Maastricht University Medical Centre, Maastricht, the Netherlands; Department of Human Biology, School for Nutrition, Toxicology and Metabolism, NUTRIM, Maastricht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.soard.2013.03.009DOI Listing
September 2014

PPAR-alpha dependent regulation of vanin-1 mediates hepatic lipid metabolism.

J Hepatol 2014 Aug 18;61(2):366-72. Epub 2014 Apr 18.

Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; Nutrition, Metabolism and Genomics Group, Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jhep.2014.04.013DOI Listing
August 2014

High-fat diet-induced mitochondrial biogenesis is regulated by mitochondrial-derived reactive oxygen species activation of CaMKII.

Diabetes 2014 Jun 11;63(6):1907-13. Epub 2014 Feb 11.

Department of Human Health & Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada

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http://dx.doi.org/10.2337/db13-0816DOI Listing
June 2014

Can resveratrol help to maintain metabolic health?

Proc Nutr Soc 2014 May 14;73(2):271-7. Epub 2014 Jan 14.

Department of Human Biology, Maastricht University Medical Center, NUTRIM School for Nutrition, Toxicology and Metabolism, P.O. Box 616, NL-6200 MD Maastricht, The Netherlands.

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http://dx.doi.org/10.1017/S0029665113003856DOI Listing
May 2014

Reduced incorporation of fatty acids into triacylglycerol in myotubes from obese individuals with type 2 diabetes.

Diabetes 2014 May 31;63(5):1583-1593. Epub 2014 Jan 31.

Department of Human Biology, NUTRIM-School for Nutrition, Toxicology and Metabolism, Departments of Human Biology, Maastricht University Medical Center, Maastricht, the Netherlands.

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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db13
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http://dx.doi.org/10.2337/db13-1123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023412PMC
May 2014

Identification of human exercise-induced myokines using secretome analysis.

Physiol Genomics 2014 Apr 11;46(7):256-67. Epub 2014 Feb 11.

Nutrition, Metabolism and Genomics Group, Division of Human Nutrition, Wageningen University, Wageningen, the Netherlands;

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http://physiolgenomics.physiology.org/content/physiolgenomic
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http://physiolgenomics.physiology.org/cgi/doi/10.1152/physio
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http://dx.doi.org/10.1152/physiolgenomics.00174.2013DOI Listing
April 2014

Chemical imaging of lipid droplets in muscle tissues using hyperspectral coherent Raman microscopy.

Histochem Cell Biol 2014 Mar 2;141(3):263-73. Epub 2013 Nov 2.

Molecular Spectroscopy Department, Max Plank Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.

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http://dx.doi.org/10.1007/s00418-013-1161-2DOI Listing
March 2014

Energy dissipation in brown adipose tissue: from mice to men.

Mol Cell Endocrinol 2013 Oct 28;379(1-2):43-50. Epub 2013 Apr 28.

Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center+, Maastricht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2013.04.017DOI Listing
October 2013

Cold acclimation recruits human brown fat and increases nonshivering thermogenesis.

J Clin Invest 2013 Aug 15;123(8):3395-403. Epub 2013 Jul 15.

Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre+ (MUMC+), Maastricht, Netherlands.

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http://www.jci.org/articles/view/68993
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http://dx.doi.org/10.1172/JCI68993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726172PMC
August 2013

Brown adipose tissue activity after a high-calorie meal in humans.

Am J Clin Nutr 2013 Jul 29;98(1):57-64. Epub 2013 May 29.

Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center+ Maastricht, The Netherlands.

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https://academic.oup.com/ajcn/article/98/1/57/4578341
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http://dx.doi.org/10.3945/ajcn.113.059022DOI Listing
July 2013

Increased oxygen consumption in human adipose tissue from the "brown adipose tissue" region.

J Clin Endocrinol Metab 2013 Jul 19;98(7):E1230-4. Epub 2013 Jun 19.

Department of Human Biology, Maastricht University, PO Box 616, 6200 MD Maastricht, the Netherlands.

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http://dx.doi.org/10.1210/jc.2013-1348DOI Listing
July 2013

Therapeutic potential of resveratrol in obesity and type 2 diabetes: new avenues for health benefits?

Ann N Y Acad Sci 2013 Jul;1290:83-9

Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center, Maastricht, the Netherlands.

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http://dx.doi.org/10.1111/nyas.12185DOI Listing
July 2013

Blocking the entrance to open the gate.

Diabetes 2013 Mar;62(3):703-5

Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.2337/db12-1663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581194PMC
March 2013

Systemic β-adrenergic stimulation of thermogenesis is not accompanied by brown adipose tissue activity in humans.

Diabetes 2012 Dec 7;61(12):3106-13. Epub 2012 Aug 7.

Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center, Maastricht, the Netherlands.

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http://diabetes.diabetesjournals.org/cgi/doi/10.2337/db12-02
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http://dx.doi.org/10.2337/db12-0288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501890PMC
December 2012

Impact of dietary fat quantity and quality on skeletal muscle fatty acid metabolism in subjects with the metabolic syndrome.

Metabolism 2012 Nov 1;61(11):1554-65. Epub 2012 Jun 1.

Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre+, 6200 MD Maastricht, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S00260495120012
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http://dx.doi.org/10.1016/j.metabol.2012.04.003DOI Listing
November 2012

Perilipin 2 improves insulin sensitivity in skeletal muscle despite elevated intramuscular lipid levels.

Diabetes 2012 Nov 17;61(11):2679-90. Epub 2012 Jul 17.

Department of Human Biology, NUTRIM School for Nutrition, Toxicology, and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands.

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http://dx.doi.org/10.2337/db11-1402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478528PMC
November 2012

High oxidative capacity due to chronic exercise training attenuates lipid-induced insulin resistance.

Diabetes 2012 Oct 10;61(10):2472-8. Epub 2012 Jul 10.

Department of Human Biology, NUTRIM School for Nutrition, Toxicology, and Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.2337/db11-1832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447923PMC
October 2012

Muscle mitochondria and insulin resistance: a human perspective.

Trends Endocrinol Metab 2012 Sep 20;23(9):444-50. Epub 2012 Jun 20.

NUTRIM - School for Nutrition, Toxicology and Metabolism, Department of Human Biology, Maastricht University Medical Center, 6200 MD Maastricht, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S10432760120008
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http://dx.doi.org/10.1016/j.tem.2012.05.007DOI Listing
September 2012

A role of active brown adipose tissue in cancer cachexia?

Oncol Rev 2012 Mar 12;6(1):e11. Epub 2012 Jun 12.

Departments of Nuclear Medicine, ; GROW School for Oncology and Developmental Biology.

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http://dx.doi.org/10.4081/oncol.2012.e11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419634PMC
March 2012

The journey of resveratrol from yeast to human.

Aging (Albany NY) 2012 Mar;4(3):146-58

Top Institute Food and Nutrition (TIFN), Wageningen, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348475PMC
http://dx.doi.org/10.18632/aging.100445DOI Listing
March 2012

The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria.

Histochem Cell Biol 2012 Feb 30;137(2):205-16. Epub 2011 Nov 30.

Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s00418-011-0888-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262136PMC
February 2012

Re-evaluating lipotoxic triggers in skeletal muscle: relating intramyocellular lipid metabolism to insulin sensitivity.

Prog Lipid Res 2012 Jan 19;51(1):36-49. Epub 2011 Nov 19.

Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre+, 6200MD Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.plipres.2011.11.003DOI Listing
January 2012

Diet or diet plus physical activity in patients with early type 2 diabetes.

Lancet 2011 Dec;378(9809):2066-7; author reply 2067-8

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http://dx.doi.org/10.1016/S0140-6736(11)61892-8DOI Listing
December 2011