Otfried Kistner

Department of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy; VisMederi Srl, Enterprise of Service in Life Sciences, 53100 Siena, Italy. Electronic address:

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January 2018

Emerging Influenza Strains in the Last Two Decades: A Threat of a New Pandemic?

Authors:

Claudia Trombetta Simona Piccirella Daniele Perini Otfried Kistner Emanuele Montomoli

Vaccines (Basel) 2015 Mar 18;3(1):172-85. Epub 2015 Mar 18.

Department of Molecular and Developmental Medicine, University of Siena, Via Aldo Moro, 53100 Siena, Italy.

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March 2015

Neuraminidase-Inhibiting Antibody Response to H5N1 Virus Vaccination in Chronically Ill and Immunocompromised Patients.

Authors:

Richard Fritz Nicole Hetzelt Reinhard Ilk Christine Hohenadl Maikel V W van der Velden Gerald Aichinger Daniel Portsmouth Otfried Kistner M Keith Howard P Noel Barrett Thomas R Kreil

Open Forum Infect Dis 2014 Sep 25;1(2):ofu072. Epub 2014 Aug 25.

Vaccine R&D , Orth/Donau.

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September 2014

Immunogenicity and protective efficacy of a Vero cell culture-derived whole-virus H7N9 vaccine in mice and guinea pigs.

Authors:

Walter Wodal Michael G Schwendinger Helga Savidis-Dacho Brian A Crowe Christine Hohenadl Richard Fritz Peter Brühl Daniel Portsmouth Anita Karner-Pichl Dalida Balta Leopold Grillberger Otfried Kistner P Noel Barrett M Keith Howard

PLoS One 2015 26;10(2):e0113963. Epub 2015 Feb 26.

Vaccine R&D, Baxter BioScience, Orth/Donau, Austria.

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November 2015

Phase I/II randomized double-blind study of the safety and immunogenicity of a nonadjuvanted vero cell culture-derived whole-virus H9N2 influenza vaccine in healthy adults.

Authors:

Gerald Aichinger Barbara Grohmann-Izay Maikel V W van der Velden Sandor Fritsch Manuela Koska Daniel Portsmouth Mary Kate Hart Wael El-Amin Otfried Kistner P Noel Barrett

Clin Vaccine Immunol 2015 Jan 29;22(1):46-55. Epub 2014 Oct 29.

Vaccine R&D, Baxter BioScience, Orth/Donau, Austria.

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January 2015

Superior in vitro stimulation of human CD8+ T-cells by whole virus versus split virus influenza vaccines.

Authors:

Benedict R Halbroth Alexander Heil Eva Distler Martin Dass Eva M Wagner Bodo Plachter Hans Christian Probst Dennis Strand Udo F Hartwig Anita Karner Gerald Aichinger Otfried Kistner Katharina Landfester Wolfgang Herr

PLoS One 2014 29;9(7):e103392. Epub 2014 Jul 29.

Department of Medicine III - University Medical Center of Johannes Gutenberg-University, Mainz, Germany; Department of Medicine III - University Medical Center of Regensburg, Regensburg, Germany.

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November 2015

Safety and immunogenicity of a vero cell culture-derived whole-virus influenza A(H5N1) vaccine in a pediatric population.

Authors:

Maikel V W van der Velden Richard Fritz Eva Maria Pöllabauer Daniel Portsmouth M Keith Howard Thomas R Kreil Thomas Dvorak Sandor Fritsch Timo Vesikari Javier Diez-Domingo Peter Richmond Bee Wah Lee Otfried Kistner Hartmut J Ehrlich P Noel Barrett Gerald Aichinger

J Infect Dis 2014 Jan 16;209(1):12-23. Epub 2013 Sep 16.

Vaccine Research and Development.

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January 2014

Preclinical evaluation of Vaxfectin-adjuvanted Vero cell-derived seasonal split and pandemic whole virus influenza vaccines.

Authors:

Larry R Smith Walter Wodal Brian A Crowe Astrid Kerschbaum Peter Bruehl Michael G Schwendinger Helga Savidis-Dacho Sean M Sullivan Mark Shlapobersky Jukka Hartikka Alain Rolland P Noel Barrett Otfried Kistner

Hum Vaccin Immunother 2013 Jun 6;9(6):1333-45. Epub 2013 Mar 6.

Vical Incorporated; San Diego, CA USA.

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June 2013

Lack of innate interferon responses during SARS coronavirus infection in a vaccination and reinfection ferret model.

PLoS One 2012 24;7(9):e45842. Epub 2012 Sep 24.

Division of Experimental Therapeutics, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.

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February 2013

Cell culture (Vero cell) derived whole-virus non-adjuvanted H5N1 influenza vaccine induces long-lasting cross-reactive memory immune response: homologous or heterologous booster response following two dose or single dose priming.

Authors:

Maikel V W van der Velden Gerald Aichinger Eva Maria Pöllabauer Alexandra Löw-Baselli Sandor Fritsch Karima Benamara Otfried Kistner Markus Müller Markus Zeitlinger Herwig Kollaritsch Timo Vesikari Hartmut J Ehrlich P Noel Barrett

Vaccine 2012 Sep 8;30(43):6127-35. Epub 2012 Aug 8.

Vaccine R&D, Baxter BioScience, Vienna, Austria.

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September 2012

A non-adjuvanted whole-virus H1N1 pandemic vaccine is well tolerated and highly immunogenic in children and adolescents and induces substantial immunological memory.

Authors:

Alexandra Loew-Baselli Borislava G Pavlova Sandor Fritsch Eva Maria Poellabauer Wolfgang Draxler Otfried Kistner Ulrich Behre Rudolf Angermayr Johannes Neugebauer Karola Kirsten Elisabeth Förster-Waldl Ralph Koellges Hartmut J Ehrlich P Noel Barrett

Vaccine 2012 Sep 28;30(41):5956-66. Epub 2012 Jul 28.

Global R&D, Baxter BioScience, Vienna, Austria.

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September 2012

A cell culture-derived whole-virus H5N1 vaccine induces long-lasting cross-clade protective immunity in mice which is augmented by a homologous or heterologous booster vaccination.

Authors:

Nicolas Sabarth Helga Savidis-Dacho Michael G Schwendinger Peter Brühl Daniel Portsmouth Brian A Crowe Otfried Kistner P Noel Barrett Thomas R Kreil M Keith Howard

Vaccine 2012 Aug 29;30(37):5533-40. Epub 2012 Jun 29.

Vaccine R&D, Baxter BioScience, Biomedical Research Centre, Uferstraße 15, A-2304 Orth/Donau, Austria.

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August 2012

A cell culture-derived whole-virus H9N2 vaccine induces high titer antibodies against hemagglutinin and neuraminidase and protects mice from severe lung pathology and weight loss after challenge with a highly virulent H9N2 isolate.

Authors:

Walter Wodal Falko G Falkner Astrid Kerschbaum Claudia Gaiswinkler Richard Fritz Stefan Kiermayr Daniel Portsmouth Helga Savidis-Dacho Sogue Coulibaly Christina Piskernik Christine Hohenadl M Keith Howard Otfried Kistner P Noel Barrett Thomas R Kreil

Vaccine 2012 Jun 10;30(31):4625-31. Epub 2012 May 10.

Vaccine R&D, Baxter BioScience, Biomedical Research Centre, Orth/Donau, Austria.

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June 2012

Pre-vaccination immunity and immune responses to a cell culture-derived whole-virus H1N1 vaccine are similar to a seasonal influenza vaccine.

Authors:

Hartmut J Ehrlich Markus Müller Herwig Kollaritsch Fritz Pinl Bernhard Schmitt Markus Zeitlinger Alexandra Loew-Baselli Thomas R Kreil Otfried Kistner Daniel Portsmouth Sandor Fritsch Friedrich Maritsch Gerald Aichinger Borislava G Pavlova P Noel Barrett

Vaccine 2012 Jun 1;30(30):4543-51. Epub 2012 Apr 1.

Global R&D, Baxter BioScience, Vienna, Austria. hartmut

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June 2012

A cell culture-derived influenza vaccine provides consistent protection against infection and reduces the duration and severity of disease in infected individuals.

Authors:

Hartmut J Ehrlich Julia Singer Gregory Berezuk Sandor Fritsch Gerald Aichinger Mary Kate Hart Wael El-Amin Daniel Portsmouth Otfried Kistner P Noel Barrett

Clin Infect Dis 2012 Apr 19;54(7):946-54. Epub 2012 Jan 19.

Global R&D, Baxter BioScience, Vienna, Austria.

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April 2012

Clinical development of a Vero cell culture-derived seasonal influenza vaccine.

Authors:

Hartmut J Ehrlich Gregory Berezuk Sandor Fritsch Gerald Aichinger Julia Singer Daniel Portsmouth Mary Kate Hart Wael El-Amin Otfried Kistner P Noel Barrett

Vaccine 2012 Jun 13;30(29):4377-86. Epub 2011 Dec 13.

Global R&D, Baxter BioScience, IZD Tower, Wagramerstraße 17-19, A-1220 Vienna, Austria.

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June 2012

A vero cell-derived whole-virus H5N1 vaccine effectively induces neuraminidase-inhibiting antibodies.

Authors:

Richard Fritz Nicolas Sabarth Stefan Kiermayr Christine Hohenadl M Keith Howard Reinhard Ilk Otfried Kistner Hartmut J Ehrlich P Noel Barrett Thomas R Kreil

J Infect Dis 2012 Jan 16;205(1):28-34. Epub 2011 Nov 16.

Baxter BioScience, Vaccine Research and Development, Orth an der Donau, Austria.

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January 2012

Safety and immunogenicity of two different doses of a Vero cell-derived, whole virus clade 2 H5N1 (A/Indonesia/05/2005) influenza vaccine.

Authors:

Paul A Tambyah Annelies Wilder-Smith Borislava G Pavlova P Noel Barrett Helen M L Oh David S Hui Kwok-yung Yuen Sandor Fritsch Gerald Aichinger Alexandra Loew-Baselli Maikel van der Velden Friedrich Maritsch Otfried Kistner Hartmut J Ehrlich

Vaccine 2012 Jan 12;30(2):329-35. Epub 2011 Nov 12.

National University Hospital, 5 Lower Kent Ridge Road, Singapore.

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January 2012

Safety and immunogenicity of an inactivated whole virus Vero cell-derived Ross River virus vaccine: a randomized trial.

Authors:

Gerald Aichinger Hartmut J Ehrlich John G Aaskov Sandor Fritsch Christiane Thomasser Wolfgang Draxler Michael Wolzt Markus Müller Fritz Pinl Pierre Van Damme Annick Hens Jack Levy Daniel Portsmouth Georg Holzer Otfried Kistner Thomas R Kreil P Noel Barrett

Vaccine 2011 Nov 12;29(50):9376-84. Epub 2011 Oct 12.

Global R&D, Baxter BioScience, IZD Tower, Wagramerstraße 17-19, A-1220 Vienna, Austria. gerald

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November 2011

H5N1 whole-virus vaccine induces neutralizing antibodies in humans which are protective in a mouse passive transfer model.

Authors:

M Keith Howard Nicolas Sabarth Helga Savidis-Dacho Daniel Portsmouth Otfried Kistner Thomas R Kreil Hartmut J Ehrlich P Noel Barrett

PLoS One 2011 18;6(8):e23791. Epub 2011 Aug 18.

Vaccine Research and Development, Baxter BioScience, Orth/Donau, Austria.

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December 2011

Evaluation of an inactivated Ross River virus vaccine in active and passive mouse immunization models and establishment of a correlate of protection.

Authors:

Georg W Holzer Sogue Coulibaly Gerald Aichinger Helga Savidis-Dacho Josef Mayrhofer Susanne Brunner Karl Schmid Otfried Kistner John G Aaskov Falko G Falkner Hartmut Ehrlich P Noel Barrett Thomas R Kreil

Vaccine 2011 May 6;29(24):4132-41. Epub 2011 Apr 6.

Baxter Bioscience, Biomedical Research Center, A-2304 Orth/Donau, Austria.

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May 2011

Efficacy, safety, and immunogenicity of a Vero-cell-culture-derived trivalent influenza vaccine: a multicentre, double-blind, randomised, placebo-controlled trial.

Authors:

P Noel Barrett Gregory Berezuk Sandor Fritsch Gerald Aichinger Mary Kate Hart Wael El-Amin Otfried Kistner Hartmut J Ehrlich

Lancet 2011 Feb 15;377(9767):751-9. Epub 2011 Feb 15.

Global Research and Development, Baxter BioScience, Biomedical Research Centre, Orth/Donau, Austria.

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February 2011

Evaluation of the cellular immune responses induced by a non-adjuvanted inactivated whole virus A/H5N1/VN/1203 pandemic influenza vaccine in humans.

Authors:

Brian A Crowe Peter Brühl Marijan Gerencer Michael G Schwendinger Andreas Pilz Otfried Kistner Katrin Koelling-Schlebusch Gerald Aichinger Julia Singer Markus Zeitlinger Markus Müller Hartmut Ehrlich P Noel Barrett

Vaccine 2010 Dec 4;29(2):166-73. Epub 2010 Nov 4.

Baxter Bioscience, Biomedical Research Centre, Uferstr. 15, A-2304 Orth an der Donau, Austria. brian

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December 2010

A pandemic influenza H1N1 live vaccine based on modified vaccinia Ankara is highly immunogenic and protects mice in active and passive immunizations.

Authors:

Annett Hessel Michael Schwendinger Daniela Fritz Sogue Coulibaly Georg W Holzer Nicolas Sabarth Otfried Kistner Walter Wodal Astrid Kerschbaum Helga Savidis-Dacho Brian A Crowe Thomas R Kreil P Noel Barrett Falko G Falkner

PLoS One 2010 Aug 16;5(8):e12217. Epub 2010 Aug 16.

R&D Vaccines, Biomedical Research Center, Baxter BioScience, Orth/Donau, Austria.

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August 2010

An inactivated West Nile Virus vaccine derived from a chemically synthesized cDNA system.

Authors:

Klaus K Orlinger Georg W Holzer Julia Schwaiger Josef Mayrhofer Karl Schmid Otfried Kistner P Noel Barrett Falko G Falkner

Vaccine 2010 Apr 6;28(19):3318-24. Epub 2010 Mar 6.

Baxter Bioscience, Biomedical Research Center, Uferstrasse 15, A-2304 Orth/Donau, Austria.

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April 2010

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