Ole Kiehn

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Ole Kiehn

Publications by authors named "Ole Kiehn"

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55Publications

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Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types.

Nat Neurosci 2018 Jun 23;21(6):869-880. Epub 2018 Apr 23.

Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.

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June 2018

Sacral Spinal Cord Transection and Isolated Sacral Cord Preparation to Study Chronic Spinal Cord Injury in Adult Mice.

Bio Protoc 2018 Apr;8(7):e2784

Department of Neuroscience, University of Copenhagen, Copenhagen, Denmark.

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April 2018

Spatiotemporal correlation of spinal network dynamics underlying spasms in chronic spinalized mice.

Elife 2017 02 13;6. Epub 2017 Feb 13.

Mammalian locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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February 2017

Spinal Hb9::Cre-derived excitatory interneurons contribute to rhythm generation in the mouse.

Sci Rep 2017 Jan 27;7:41369. Epub 2017 Jan 27.

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden.

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January 2017

Decoding the organization of spinal circuits that control locomotion.

Authors:
Ole Kiehn

Nat Rev Neurosci 2016 Apr 3;17(4):224-38. Epub 2016 Mar 3.

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Retziusväg 8, 17177 Stockholm, Sweden.

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April 2016

Descending Command Neurons in the Brainstem that Halt Locomotion.

Cell 2015 Nov;163(5):1191-1203

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden. Electronic address:

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November 2015

Editorial overview: Motor circuits and action.

Curr Opin Neurobiol 2015 Aug 30;33:v-vi. Epub 2015 Jun 30.

Department of Neuroscience, Grossman Center for the Statistics of Mind, David Mahoney Center for Brain and Behavior Research, Kavli Institute for Brain Science, Columbia University Medical Center, New York, NY 10032, United States. Electronic address:

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August 2015

Organization of left-right coordination of neuronal activity in the mammalian spinal cord: Insights from computational modelling.

J Physiol 2015 Jun;593(11):2403-26

Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, USA.

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June 2015

Phenotypic characterization of speed-associated gait changes in mice reveals modular organization of locomotor networks.

Curr Biol 2015 Jun 7;25(11):1426-36. Epub 2015 May 7.

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Stockholm 17177, Sweden. Electronic address:

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June 2015

Neuronal calcium-binding proteins 1/2 localize to dorsal root ganglia and excitatory spinal neurons and are regulated by nerve injury.

Proc Natl Acad Sci U S A 2014 Mar 10;111(12):E1149-58. Epub 2014 Mar 10.

Department of Neuroscience, Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, and Science for Life Laboratory, Department of Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden.

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March 2014

Spinal glutamatergic neurons defined by EphA4 signaling are essential components of normal locomotor circuits.

J Neurosci 2014 Mar;34(11):3841-53

Department of Neuroscience, Karolinska Institutet, S-17177 Stockholm, Sweden, Faculty of Medicine and College of Biological Sciences, University of Tsukuba, 305-8577 Tsukuba, Japan, RIKEN Brain Science Institute, 351-0198 Wako, Japan, and National Institute of Genetics, SOKENDAI, 411-8540 Mishima, Japan.

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March 2014

Modelling genetic reorganization in the mouse spinal cord affecting left-right coordination during locomotion.

J Physiol 2013 Nov 30;591(22):5491-508. Epub 2013 Sep 30.

I. A. Rybak: Department of Neurobiology and Anatomy, Drexel University College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USA.

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November 2013

Locomotor rhythm generation linked to the output of spinal shox2 excitatory interneurons.

Neuron 2013 Nov;80(4):920-33

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden.

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November 2013

Dual-mode operation of neuronal networks involved in left-right alternation.

Nature 2013 Aug 30;500(7460):85-8. Epub 2013 Jun 30.

The Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Stockholm S-17177, Sweden.

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August 2013

Optogenetic dissection reveals multiple rhythmogenic modules underlying locomotion.

Proc Natl Acad Sci U S A 2013 Jul 24;110(28):11589-94. Epub 2013 Jun 24.

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, S-17177 Stockholm, Sweden.

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July 2013

Medial septal dysfunction by Aβ-induced KCNQ channel-block in glutamatergic neurons.

Neurobiol Aging 2012 Sep 9;33(9):2046-61. Epub 2011 Sep 9.

Neuronal Oscillations Laboratory, KI Alzheimer's Disease Research Center, NVS, Karolinska Institute, Stockholm, Sweden.

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September 2012

Change in the balance of excitatory and inhibitory midline fiber crossing as an explanation for the hopping phenotype in EphA4 knockout mice.

Eur J Neurosci 2011 Oct 7;34(7):1102-12. Epub 2011 Sep 7.

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Retzius väg 8, Stockholm, Sweden.

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October 2011

Identification of minimal neuronal networks involved in flexor-extensor alternation in the mammalian spinal cord.

Neuron 2011 Sep 21;71(6):1071-84. Epub 2011 Sep 21.

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Stockholm S-17177, Sweden.

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September 2011

Glutamatergic mechanisms for speed control and network operation in the rodent locomotor CpG.

Front Neural Circuits 2010 6;4. Epub 2010 Aug 6.

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet Stockholm, Sweden.

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July 2011

Development and functional organization of spinal locomotor circuits.

Authors:
Ole Kiehn

Curr Opin Neurobiol 2011 Feb;21(1):100-9

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Retzius väg 8, 17177 Stockholm, Sweden.

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February 2011

The transcription factors Nkx2.2 and Nkx2.9 play a novel role in floor plate development and commissural axon guidance.

Development 2010 Dec 10;137(24):4249-60. Epub 2010 Nov 10.

Cell and Molecular Biology, University of Braunschweig, Spielmannstrasse 7, 38106 Braunschweig, Germany.

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December 2010

A transgenic mouse line for molecular genetic analysis of excitatory glutamatergic neurons.

Mol Cell Neurosci 2010 Nov 1;45(3):245-57. Epub 2010 Jul 1.

Mammalian Locomotor Laboratory, Karolinska Institutet, Retzius väg 8, 17177 Stockholm, Sweden.

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November 2010

Transcriptional regulation of gene expression clusters in motor neurons following spinal cord injury.

BMC Genomics 2010 Jun 9;11:365. Epub 2010 Jun 9.

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Retzius väg 8, 171 77 Stockholm, Sweden.

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June 2010

Functional organization of V2a-related locomotor circuits in the rodent spinal cord.

Ann N Y Acad Sci 2010 Jun;1198:85-93

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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June 2010

Probing spinal circuits controlling walking in mammals.

Biochem Biophys Res Commun 2010 May;396(1):11-8

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Retzius väg 8, 17177 Stockholm, Sweden.

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May 2010

Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion.

Nat Neurosci 2010 Feb 17;13(2):246-52. Epub 2010 Jan 17.

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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February 2010

Firing and cellular properties of V2a interneurons in the rodent spinal cord.

J Neurosci 2010 Jan;30(1):24-37

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Stockholm S-171 77, Sweden.

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January 2010

Transmitter-phenotypes of commissural interneurons in the lumbar spinal cord of newborn mice.

J Comp Neurol 2009 Nov;517(2):177-92

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden.

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November 2009

Asymmetric operation of the locomotor central pattern generator in the neonatal mouse spinal cord.

J Neurophysiol 2008 Dec 1;100(6):3043-54. Epub 2008 Oct 1.

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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December 2008

Gene expression profiling of two distinct neuronal populations in the rodent spinal cord.

PLoS One 2008 15;3(10):e3415. Epub 2008 Oct 15.

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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December 2008

Excitatory components of the mammalian locomotor CPG.

Brain Res Rev 2008 Jan 7;57(1):56-63. Epub 2007 Nov 7.

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Retzius väg 8, 171 77 Stockholm, Sweden.

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January 2008

Phenotype of V2-derived interneurons and their relationship to the axon guidance molecule EphA4 in the developing mouse spinal cord.

Eur J Neurosci 2007 Dec;26(11):2989-3002

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Retzius väg 8, 171 77 Stockholm, Sweden.

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December 2007

Segmental, synaptic actions of commissural interneurons in the mouse spinal cord.

J Neurosci 2007 Jun;27(24):6521-30

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institute, 17177 Stockholm, Sweden.

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June 2007

Locomotor circuits in the mammalian spinal cord.

Authors:
Ole Kiehn

Annu Rev Neurosci 2006 ;29:279-306

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Stockholm S17177, Sweden.

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September 2006

Activity of Renshaw cells during locomotor-like rhythmic activity in the isolated spinal cord of neonatal mice.

J Neurosci 2006 May;26(20):5320-8

Department of Neuroscience, Karolinska Institute, Stockholm S-171 77, Sweden.

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May 2006

V1 spinal neurons regulate the speed of vertebrate locomotor outputs.

Nature 2006 Mar;440(7081):215-9

Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.

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March 2006

EphA4 defines a class of excitatory locomotor-related interneurons.

Proc Natl Acad Sci U S A 2005 Sep 19;102(39):14098-103. Epub 2005 Sep 19.

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Stockholm S-171 77, Sweden.

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September 2005

Glial and neuronal connexin expression patterns in the rat spinal cord during development and following injury.

J Comp Neurol 2005 Aug;489(1):1-10

Department of Neuroscience, Karolinska Institute, 17177 Stockholm, Sweden.

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August 2005

Mammalian motor neurons corelease glutamate and acetylcholine at central synapses.

Proc Natl Acad Sci U S A 2005 Apr 21;102(14):5245-9. Epub 2005 Mar 21.

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Retzius väg 8, 171 77 Stockholm, Sweden.

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April 2005

Central pattern generators deciphered by molecular genetics.

Neuron 2004 Feb;41(3):317-21

Mammalian Locomotor Laboratory, Department of Neuroscience, The Karolinska Institute, Retzius vag 8, 171 77 Stockholm, Sweden.

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February 2004

Synaptic targets of commissural interneurons in the lumbar spinal cord of neonatal rats.

J Comp Neurol 2003 Jul;461(4):429-40

Department of Anatomy, Faculty of Medicine, Medical and Health Science Center, University of Debrecen, Debrecen, H-4012 Hungary.

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July 2003

Physiological, anatomical and genetic identification of CPG neurons in the developing mammalian spinal cord.

Prog Neurobiol 2003 Jul;70(4):347-61

Department of Neuroscience, Karolinska Institutet, Retzius väg 8, 171 77 Stockholm, Sweden.

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July 2003

Functional identification of interneurons responsible for left-right coordination of hindlimbs in mammals.

Neuron 2003 Jun;38(6):953-63

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Retzius väg 8, 171 77, Stockholm, Sweden.

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June 2003

Role of EphA4 and EphrinB3 in local neuronal circuits that control walking.

Science 2003 Mar;299(5614):1889-92

Department of Medical Biochemistry, Gothenburg University, Medicinaregatan 9 A, 405 30 Gothenburg, Sweden.

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March 2003

Mechanisms underlying the noradrenergic modulation of longitudinal coordination during swimming in Xenopus laevis tadpoles.

Eur J Neurosci 2003 Mar;17(5):1013-22

School of Biology, Bute Medical Buildings, University of St Andrews, St Andrews, Fife, KY16 8LB, Scotland.

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March 2003

Firing properties of identified interneuron populations in the mammalian hindlimb central pattern generator.

J Neurosci 2002 Nov;22(22):9961-71

Mammalian Locomotor Laboratory, Department of Neuroscience, Karolinska Institutet, Stockholm S-171 77, Sweden.

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November 2002

Synchronization of motor neurons during locomotion in the neonatal rat: predictors and mechanisms.

J Neurosci 2002 Nov;22(22):9997-10008

Department of Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden.

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November 2002

Organization of left-right coordination in the mammalian locomotor network.

Brain Res Brain Res Rev 2002 Oct;40(1-3):107-17

Department of Neuroscience, Karolinska Institutet, Retzius Vag 8, S-171 77, Stockholm, Sweden.

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October 2002

Projection patterns of commissural interneurons in the lumbar spinal cord of the neonatal rat.

J Comp Neurol 2002 May;446(4):349-59

Department of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden.

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May 2002

Gap junctions and motor behavior.

Trends Neurosci 2002 Feb;25(2):108-15

Dept of Neuroscience, Karolinska Institutet, Retzius Vag 8, S-171 77, Stockholm, Sweden.

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February 2002