Nikolas K Haass

Nikolas K Haass

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Nikolas K Haass

Nikolas K Haass

Publications by authors named "Nikolas K Haass"

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Mathematical models incorporating a multi-stage cell cycle replicate normally-hidden inherent synchronization in cell proliferation.

J R Soc Interface 2019 Aug 21;16(157):20190382. Epub 2019 Aug 21.

School of Mathematical Sciences, Queensland University of Technology, Brisbane, Queensland 4001, Australia.

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http://dx.doi.org/10.1098/rsif.2019.0382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731503PMC
August 2019

Magnolol induces cell death through PI3K/Akt-mediated epigenetic modifications boosting treatment of BRAF- and NRAS-mutant melanoma.

Cancer Med 2019 Mar 21;8(3):1186-1196. Epub 2019 Feb 21.

Dermatology Research Centre, The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1002/cam4.1978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434221PMC
March 2019

The Role of Melanoma Cell-Stroma Interaction in Cell Motility, Invasion, and Metastasis.

Front Med (Lausanne) 2018 6;5:307. Epub 2018 Nov 6.

The University of Queensland, The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, QLD, Australia.

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http://dx.doi.org/10.3389/fmed.2018.00307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232165PMC
November 2018

FGFR2-activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancer cell models.

J Cell Sci 2018 08 10;131(15). Epub 2018 Aug 10.

School of Biomedical Sciences, Queensland University of Technology (QUT) located at the Translational Research Institute, Woolloongabba, Brisbane, QLD 4102, Australia

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http://jcs.biologists.org/lookup/doi/10.1242/jcs.213678
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http://dx.doi.org/10.1242/jcs.213678DOI Listing
August 2018

Endogenous Replication Stress Marks Melanomas Sensitive to CHEK1 Inhibitors .

Clin Cancer Res 2018 06 13;24(12):2901-2912. Epub 2018 Mar 13.

Mater Research Institute, The University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-2701DOI Listing
June 2018

Microenvironment-Driven Dynamic Heterogeneity and Phenotypic Plasticity as a Mechanism of Melanoma Therapy Resistance.

Front Oncol 2018 24;8:173. Epub 2018 May 24.

The University of Queensland Diamantina Institute, Translational Research Institute, The University of Queensland, Brisbane, QLD, Australia.

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http://dx.doi.org/10.3389/fonc.2018.00173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976798PMC
May 2018

Real-Time Cell Cycle Imaging in a 3D Cell Culture Model of Melanoma.

Methods Mol Biol 2017 ;1612:401-416

The University of Queensland Diamantina Institute, Translational Research Institute, The University of Queensland, 37 Kent St, Woolloongabba, Brisbane, QLD, 4102, Australia.

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http://dx.doi.org/10.1007/978-1-4939-7021-6_29DOI Listing
March 2018

Acetylsalicylic Acid Governs the Effect of Sorafenib in -Mutant Cancers.

Clin Cancer Res 2018 03 1;24(5):1090-1102. Epub 2017 Dec 1.

Dermatology Research Centre, The University of Queensland, The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844814PMC
March 2018

Mathematical Models for Cell Migration with Real-Time Cell Cycle Dynamics.

Biophys J 2018 03;114(5):1241-1253

School of Mathematical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2017.12.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883567PMC
March 2018

Cell cycle-tailored targeting of metastatic melanoma: Challenges and opportunities.

Exp Dermatol 2017 07 20;26(7):649-655. Epub 2017 Apr 20.

Mater Medical Research Institute, Translational Research Institute, The University of Queensland, Brisbane, Qld, Australia.

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http://dx.doi.org/10.1111/exd.13303DOI Listing
July 2017

Dendritic Mesoporous Silica Nanoparticles for pH-Stimuli-Responsive Drug Delivery of TNF-Alpha.

Adv Healthc Mater 2017 Jul 29;6(13). Epub 2017 May 29.

Department of Dermatology, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckstrasse 1,, 55131, Mainz, Germany.

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http://dx.doi.org/10.1002/adhm.201700012DOI Listing
July 2017

NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF.

EBioMedicine 2017 Feb 16;16:63-75. Epub 2017 Jan 16.

School of Biomedical Sciences, Institute of Health and Biomedical Innovation at the Translational Research Institute, Queensland University of Technology, Woolloongabba, QLD 4102, Australia; Dermatology Research Centre, The University of Queensland, School of Medicine, Translational Research Institute, Brisbane, QLD 4102, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474438PMC
February 2017

Multimodal tumor suppression by miR-302 cluster in melanoma and colon cancer.

Int J Biochem Cell Biol 2016 12 10;81(Pt A):121-132. Epub 2016 Nov 10.

Department of Medical Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2016.11.004DOI Listing
December 2016

Cell Cycle Phase-Specific Drug Resistance as an Escape Mechanism of Melanoma Cells.

J Invest Dermatol 2016 07 10;136(7):1479-1489. Epub 2016 Mar 10.

The Centenary Institute, Newtown, NSW, Australia; The University of Queensland, The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia; Discipline of Dermatology, University of Sydney, Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.02.805DOI Listing
July 2016

microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB.

Oncotarget 2016 May;7(22):31663-80

Laboratory for Cancer Medicine, Harry Perkins Institute of Medical Research and University of Western Australia Centre for Medical Research, Nedlands, WA, Australia.

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http://dx.doi.org/10.18632/oncotarget.9421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077967PMC
May 2016

Switching the sphingolipid rheostat in the treatment of diabetes and cancer comorbidity from a problem to an advantage.

Biomed Res Int 2015 19;2015:165105. Epub 2015 Mar 19.

School of Medical and Molecular Biosciences, University of Technology Sydney, Ultimo, NSW 2007, Australia ; Sydney Medical School, University of Sydney, Camperdown, NSW 2050, Australia.

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http://dx.doi.org/10.1155/2015/165105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383402PMC
December 2015

Imaging- and Flow Cytometry-based Analysis of Cell Position and the Cell Cycle in 3D Melanoma Spheroids.

J Vis Exp 2015 Dec 28(106):e53486. Epub 2015 Dec 28.

The Centenary Institute; The University of Queensland Diamantina Institute, Translational Research Institute, The University of Queensland; Discipline of Dermatology, University of Sydney.

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http://dx.doi.org/10.3791/53486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780858PMC
December 2015

Friends or foes: IL-10 and TGF-β in melanoma.

Exp Dermatol 2015 Apr;24(4):254-5

The Centenary Institute, Newtown, NSW, Australia; Sydney Medical School, University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1111/exd.12661DOI Listing
April 2015

Induction of endoplasmic reticulum stress as a strategy for melanoma therapy: is there a future?

Melanoma Manag 2014 Nov 4;1(2):127-137. Epub 2014 Dec 4.

The Centenary Institute, Newtown, New South Wales, Australia.

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http://dx.doi.org/10.2217/mmt.14.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094617PMC
November 2014

Targeting glutamine transport to suppress melanoma cell growth.

Int J Cancer 2014 Sep 17;135(5):1060-71. Epub 2014 Feb 17.

Origins of Cancer Laboratory, Centenary Institute, Camperdown, NSW, Australia; Gene and Stem Cell Therapy Program, Centenary Institute, Camperdown, NSW, Australia; Sydney Medical School, University of Sydney, NSW, Australia.

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http://dx.doi.org/10.1002/ijc.28749DOI Listing
September 2014

Real-time cell cycle imaging during melanoma growth, invasion, and drug response.

Pigment Cell Melanoma Res 2014 Sep 27;27(5):764-76. Epub 2014 Jun 27.

The Centenary Institute, Newtown, NSW, Australia; Discipline of Dermatology, University of Sydney, Sydney, NSW, Australia; Department of Dermatology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia; The University of Queensland Diamantina Institute, Translational Research Institute, The University of Queensland, Brisbane, Qld, Australia.

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http://dx.doi.org/10.1111/pcmr.12274DOI Listing
September 2014

Detection of primary melanoma in individuals at extreme high risk: a prospective 5-year follow-up study.

JAMA Dermatol 2014 Aug;150(8):819-27

Discipline of Dermatology, University of Sydney at the Sydney Cancer Centre, Sydney, New South Wales, Australia2Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia3Sydney Melanoma Diagnostic Centre, Sydney Cancer Centre, Sydney, New South.

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http://dx.doi.org/10.1001/jamadermatol.2014.514DOI Listing
August 2014

Targeting the intrinsic apoptosis pathway as a strategy for melanoma therapy.

Pigment Cell Melanoma Res 2014 Jul 9;27(4):525-39. Epub 2014 Apr 9.

The Centenary Institute, Newtown, NSW, Australia; School of Biological Sciences, Universiti Sains Malaysia, Penang, Malaysia.

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http://dx.doi.org/10.1111/pcmr.12242DOI Listing
July 2014

Melanoma never says die.

Exp Dermatol 2014 Jul;23(7):471-2

The University of Queensland, The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Qld, Australia; The Centenary Institute, Newtown, NSW, Australia; Discipline of Dermatology, University of Sydney, Camperdown, NSW, Australia.

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http://dx.doi.org/10.1111/exd.12400DOI Listing
July 2014

Modeling Melanoma In Vitro and In Vivo.

Healthcare (Basel) 2013 Dec 23;2(1):27-46. Epub 2013 Dec 23.

The Centenary Institute, Newtown, New South Wales 2042, Australia.

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http://dx.doi.org/10.3390/healthcare2010027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934492PMC
December 2013

DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma.

Pigment Cell Melanoma Res 2013 Nov 5;26(6):805-16. Epub 2013 Aug 5.

The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Qld, Australia.

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http://dx.doi.org/10.1111/pcmr.12136DOI Listing
November 2013

Melanoma's connections to the tumour microenvironment.

Pathology 2013 08;45(5):443-52

Department of Dermatology and Venerology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1097/PAT.0b013e328363b3bdDOI Listing
August 2013

Modulation of NOXA and MCL-1 as a strategy for sensitizing melanoma cells to the BH3-mimetic ABT-737.

Clin Cancer Res 2012 Feb 15;18(3):783-95. Epub 2011 Dec 15.

The Centenary Institute, Newtown, New South Wales, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-1166DOI Listing
February 2012

Evaluation of cell cycle arrest in estrogen responsive MCF-7 breast cancer cells: pitfalls of the MTS assay.

PLoS One 2011 3;6(6):e20623. Epub 2011 Jun 3.

Translational Cancer Research Group, School of Medical and Molecular Biosciences, Faculty of Science, University of Technology Sydney, Sydney, New South Wales, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020623PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108819PMC
September 2011

Genetics of basal cell carcinoma.

Australas J Dermatol 2010 May;51(2):81-92; quiz 93-4

Department of Dermatology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

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http://doi.wiley.com/10.1111/j.1440-0960.2009.00579.x
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http://dx.doi.org/10.1111/j.1440-0960.2009.00579.xDOI Listing
May 2010

Melanoma biomarkers: current status and utility in diagnosis, prognosis, and response to therapy.

Mol Diagn Ther 2009 ;13(5):283-96

Discipline of Dermatology, University of Sydney, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.2165/11317270-000000000-00000DOI Listing
January 2010

Melanoma progression exhibits a significant impact on connexin expression patterns in the epidermal tumor microenvironment.

Histochem Cell Biol 2010 Jan 21;133(1):113-24. Epub 2009 Oct 21.

Department of Dermatology and Venerology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00418-009-0654-5DOI Listing
January 2010

From Xiphophorus to melanoma--a tribute to Steven Kazianis (1966-2008).

Authors:
Nikolas K Haass

Zebrafish 2008 ;5(2):91-2

Centenary Institute of Cancer Medicine and Cell Biology, Locked Bag 6, Newtown, NSW 2042, Australia.

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http://dx.doi.org/10.1089/zeb.2008.9992DOI Listing
July 2008

Expression of integrin alpha10 is induced in malignant melanoma.

Cell Oncol 2007 ;29(5):373-86

Institute of Pathology, University Regensburg, 93053 Regensburg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617990PMC
April 2008

In vitro three-dimensional tumor microenvironment models for anticancer drug discovery.

Expert Opin Drug Discov 2008 Jan;3(1):1-10

The Wistar Institute, 3601 Spruce Street, Philadelphia, PA, 19104, USA +1 215 898 0002 ;

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http://www.tandfonline.com/doi/full/10.1517/17460441.3.1.1
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http://dx.doi.org/10.1517/17460441.3.1.1DOI Listing
January 2008

Differential induction of connexins 26 and 30 in skin tumors and their adjacent epidermis.

J Histochem Cytochem 2006 Feb 26;54(2):171-82. Epub 2005 Jul 26.

The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1369/jhc.5A6719.2005DOI Listing
February 2006

Normal human melanocyte homeostasis as a paradigm for understanding melanoma.

J Investig Dermatol Symp Proc 2005 Nov;10(2):153-63

The Wistar Institute, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1111/j.1087-0024.2005.200407.xDOI Listing
November 2005

Adhesion, migration and communication in melanocytes and melanoma.

Pigment Cell Res 2005 Jun;18(3):150-9

The Wistar Institute, Philadelphia, PA 19104, USA.

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http://doi.wiley.com/10.1111/j.1600-0749.2005.00235.x
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http://dx.doi.org/10.1111/j.1600-0749.2005.00235.xDOI Listing
June 2005

The role of altered cell-cell communication in melanoma progression.

J Mol Histol 2004 Mar;35(3):309-18

The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA.

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March 2004