Niels Eijkelkamp

Niels Eijkelkamp

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Niels Eijkelkamp

Niels Eijkelkamp

Publications by authors named "Niels Eijkelkamp"

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Human FAM173A is a mitochondrial lysine-specific methyltransferase that targets adenine nucleotide translocase and affects mitochondrial respiration.

J Biol Chem 2019 Aug 18;294(31):11654-11664. Epub 2019 Jun 18.

Department of Biosciences, Faculty of Mathematics and Natural Sciences, University of Oslo, 0316 Oslo, Norway

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http://dx.doi.org/10.1074/jbc.RA119.009045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682728PMC
August 2019

Applicability of a Modified Rat Model of Acute Arthritis for Long-Term Testing of Drug Delivery Systems.

Pharmaceutics 2019 Feb 7;11(2). Epub 2019 Feb 7.

Department of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, 3508 GA Utrecht, The Netherlands.

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http://dx.doi.org/10.3390/pharmaceutics11020070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409650PMC
February 2019

Lysine methylation by the mitochondrial methyltransferase FAM173B optimizes the function of mitochondrial ATP synthase.

J Biol Chem 2019 01 10;294(4):1128-1141. Epub 2018 Dec 10.

From the Department of Biosciences, Faculty of Mathematics and Natural Sciences, University of Oslo, 0316 Oslo, Norway and

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http://dx.doi.org/10.1074/jbc.RA118.005473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349101PMC
January 2019

First trimester placental vascularization and angiogenetic factors are associated with adverse pregnancy outcome.

Pregnancy Hypertens 2018 Jul 11;13:87-94. Epub 2018 Apr 11.

Laboratory of Neuroimmunology and Developmental Origins of Disease (NIDOD), Wilhelmina Children's Hospital, University Medical Centre Utrecht, 3584 EA Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.preghy.2018.04.008DOI Listing
July 2018

Low GRK2 Underlies Hyperalgesic Priming by Glial Cell-Derived Neurotrophic Factor.

Front Pharmacol 2018 5;9:592. Epub 2018 Jun 5.

Division of Internal Medicine, Laboratory of Neuroimmunology, Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

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http://dx.doi.org/10.3389/fphar.2018.00592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996251PMC
June 2018

Development of Recombinant Proteins to Treat Chronic Pain.

J Vis Exp 2018 04 11(134). Epub 2018 Apr 11.

Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht University; Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, Utrecht University;

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http://dx.doi.org/10.3791/57071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933454PMC
April 2018

Divergent roles of immune cells and their mediators in pain.

Rheumatology (Oxford) 2018 03;57(3):429-440

Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/rheumatology/kex308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850827PMC
March 2018

Intranasal Stem Cell Treatment as a Novel Therapy for Subarachnoid Hemorrhage.

Stem Cells Dev 2018 03 8;27(5):313-325. Epub 2018 Jan 8.

4 Laboratory of Neuroimmunology, Department of Symptom Research, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center , Houston, Texas.

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http://dx.doi.org/10.1089/scd.2017.0148DOI Listing
March 2018

Identification of FAM173B as a protein methyltransferase promoting chronic pain.

PLoS Biol 2018 02 14;16(2):e2003452. Epub 2018 Feb 14.

Laboratory of Neuroimmunology and Developmental Origins of Disease (NIDOD), University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

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http://dx.doi.org/10.1371/journal.pbio.2003452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828452PMC
February 2018

First-trimester placental vascular development in multiparous women differs from that in nulliparous women.

J Matern Fetal Neonatal Med 2018 Jan 2;31(2):209-215. Epub 2017 Feb 2.

a Department of Obstetrics , University Medical Centre Utrecht , Utrecht , the Netherlands.

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http://dx.doi.org/10.1080/14767058.2017.1280020DOI Listing
January 2018

IL4-10 Fusion Protein Is a Novel Drug to Treat Persistent Inflammatory Pain.

J Neurosci 2016 07;36(28):7353-63

Neuroimmunology Laboratory, Department of Symptom Research, MD Anderson Cancer Center, University of Texas, Houston, Texas 77030.

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http://dx.doi.org/10.1523/JNEUROSCI.0092-16.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945660PMC
July 2016

Critical role for Epac1 in inflammatory pain controlled by GRK2-mediated phosphorylation of Epac1.

Proc Natl Acad Sci U S A 2016 Mar 29;113(11):3036-41. Epub 2016 Feb 29.

Laboratory of Neuroimmunology, Department of Symptom Research, University of Texas MD Anderson Cancer Center, Houston, TX 77030;

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http://dx.doi.org/10.1073/pnas.1516036113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801297PMC
March 2016

Significant determinants of mouse pain behaviour.

PLoS One 2014 7;9(8):e104458. Epub 2014 Aug 7.

Molecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, Gower Street, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104458PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125188PMC
November 2015

Mechanical allodynia.

Pflugers Arch 2015 Jan 22;467(1):133-9. Epub 2014 May 22.

Molecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, London, WC1E 6BT, UK,

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http://dx.doi.org/10.1007/s00424-014-1532-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281368PMC
January 2015

Losing touch with opioids: New insights into a chemokine signaling cascade controlling morphine analgesia.

Authors:
Niels Eijkelkamp

Brain Behav Immun 2014 May 2;38:36-7. Epub 2014 Feb 2.

Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2014.01.016DOI Listing
May 2014

Monocytes/Macrophages control resolution of transient inflammatory pain.

J Pain 2014 May;15(5):496-506

Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, Utrecht, The Netherlands; Department of Symptom Research, University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.jpain.2014.01.491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075647PMC
May 2014

Transient receptor potential channels and mechanosensation.

Annu Rev Neurosci 2013 Jul;36:519-46

Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1146/annurev-neuro-062012-170412DOI Listing
July 2013

Neurological perspectives on voltage-gated sodium channels.

Brain 2012 Sep;135(Pt 9):2585-612

Molecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, Gower Street, London WC1E 6BT, UK.

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http://dx.doi.org/10.1093/brain/aws225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437034PMC
September 2012

Noxious mechanosensation - molecules and circuits.

Curr Opin Pharmacol 2012 Feb 3;12(1):4-8. Epub 2011 Nov 3.

Wolfson Institute for Biomedical Research, University College London, London WC1E 6BT, UK.

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http://dx.doi.org/10.1016/j.coph.2011.10.013DOI Listing
February 2012

Microglial GRK2: a novel regulator of transition from acute to chronic pain.

Brain Behav Immun 2011 Aug 5;25(6):1055-60. Epub 2011 Apr 5.

Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.bbi.2011.03.019DOI Listing
August 2011

GRK2 in sensory neurons regulates epinephrine-induced signalling and duration of mechanical hyperalgesia.

Pain 2011 Jul 22;152(7):1649-58. Epub 2011 Apr 22.

Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, 3584 EA Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.pain.2011.03.010DOI Listing
July 2011

Microglial/macrophage GRK2 determines duration of peripheral IL-1beta-induced hyperalgesia: contribution of spinal cord CX3CR1, p38 and IL-1 signaling.

Pain 2010 Sep 6;150(3):550-60. Epub 2010 Jul 6.

Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, 3584 EA Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.pain.2010.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099597PMC
September 2010

G protein-coupled receptor kinase 6 controls post-inflammatory visceral hyperalgesia.

Brain Behav Immun 2009 Jan 22;23(1):18-26. Epub 2008 Jul 22.

Laboratory of Psychoneuroimmunology, University Medical Center Utrecht, Room KC 03.068.0, Lundlaan 6, 3584 EA Utrecht, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S088915910800306
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http://dx.doi.org/10.1016/j.bbi.2008.07.006DOI Listing
January 2009

G protein-coupled receptor kinase 2 positively regulates epithelial cell migration.

EMBO J 2008 Apr 27;27(8):1206-18. Epub 2008 Mar 27.

Departamento de Biología Molecular and Centro de Biología Molecular Severo Ochoa, Universidad Autónoma de Madrid, Madrid, Spain.

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http://emboj.embopress.org/cgi/doi/10.1038/emboj.2008.55
Publisher Site
http://dx.doi.org/10.1038/emboj.2008.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367399PMC
April 2008

Physiological changes in GRK2 regulate CCL2-induced signaling to ERK1/2 and Akt but not to MEK1/2 and calcium.

J Neurochem 2008 Feb 30;104(4):979-92. Epub 2007 Oct 30.

University Medical Center Utrecht, Laboratory of Psychoneuroimmunology, Utrecht, The Netherlands.

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http://doi.wiley.com/10.1111/j.1471-4159.2007.05023.x
Publisher Site
http://dx.doi.org/10.1111/j.1471-4159.2007.05023.xDOI Listing
February 2008

Increased visceral sensitivity to capsaicin after DSS-induced colitis in mice: spinal cord c-Fos expression and behavior.

Am J Physiol Gastrointest Liver Physiol 2007 Oct 26;293(4):G749-57. Epub 2007 Jul 26.

Laboratory for Psychoneuroimmunology, Univ. Medical Center Utrecht, Rm. KC 03.063.0, Lundlaan 6, 3584 EA Utrecht, The Netherlands.

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http://dx.doi.org/10.1152/ajpgi.00114.2007DOI Listing
October 2007

G protein-coupled receptor kinase 6 controls chronicity and severity of dextran sodium sulphate-induced colitis in mice.

Gut 2007 Jun 17;56(6):847-54. Epub 2007 Jan 17.

Laboratory for Psychoneuroimmunology, University Medical Center Utrecht, Lundlaan 6, Room KC 03.063.0, 3584 EA Utrecht, The Netherlands.

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http://dx.doi.org/10.1136/gut.2006.107094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1954868PMC
June 2007

Restraint stress impairs early wound healing in mice via alpha-adrenergic but not beta-adrenergic receptors.

Brain Behav Immun 2007 May 6;21(4):409-12. Epub 2007 Mar 6.

Laboratory for Psychoneuroimmunology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.bbi.2006.11.008DOI Listing
May 2007

A role for G protein-coupled receptor kinase 2 in mechanical allodynia.

Eur J Neurosci 2007 Mar 4;25(6):1696-704. Epub 2007 Apr 4.

University Medical Center Utrecht, Laboratory of Psychoneuroimmunology, KC03.068.0, Lundlaan 6, 3584 EA, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/j.1460-9568.2007.05423.xDOI Listing
March 2007

Tissue specific effects of the beta 2-adrenergic agonist salbutamol on LPS-induced IFN-gamma, IL-10 and TGF-beta responses in vivo.

J Neuroimmunol 2004 May;150(1-2):3-9

Laboratory for Psychoneuroimmunology, University Medical Center Utrecht, Room KC03.068.0, Lundlaan 6, 3584 EA, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.jneuroim.2004.01.001DOI Listing
May 2004