Nicolas Pilon

Nicolas Pilon

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Nicolas Pilon

Nicolas Pilon

Publications by authors named "Nicolas Pilon"

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Molecular dissection of CHARGE syndrome highlights the vulnerability of neural crest cells to problems with alternative splicing and other transcription-related processes.

Transcription 2019 02 20;10(1):21-28. Epub 2018 Sep 20.

a Laboratoire de génétique moléculaire du développement, Département des sciences biologiques , Université du Québec à Montréal (UQAM) , Montréal , QC , Canada.

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http://dx.doi.org/10.1080/21541264.2018.1521213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351119PMC
February 2019

Gut microbiota-mediated Gene-Environment interaction in the TashT mouse model of Hirschsprung disease.

Sci Rep 2019 Jan 24;9(1):492. Epub 2019 Jan 24.

Département des Sciences Biologiques, Université du Québec à Montréal, Montréal, H3C 3P8, Québec, Canada.

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http://dx.doi.org/10.1038/s41598-018-36967-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345786PMC
January 2019

Dysregulation of cotranscriptional alternative splicing underlies CHARGE syndrome.

Proc Natl Acad Sci U S A 2018 01 8;115(4):E620-E629. Epub 2018 Jan 8.

Molecular Genetics of Development Laboratory, Department of Biological Sciences, University of Quebec at Montreal, Montreal, QC H2X 3Y7, Canada;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1715378115
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http://dx.doi.org/10.1073/pnas.1715378115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789929PMC
January 2018

HLX is a candidate gene for a pattern of anomalies associated with congenital diaphragmatic hernia, short bowel, and asplenia.

Am J Med Genet A 2017 Nov 12;173(11):3070-3074. Epub 2017 Sep 12.

Molecular Genetics of Development Laboratory, Department of Biological Sciences and BioMed Research Center, Faculty of Sciences, University of Quebec at Montreal, Montreal, Quebec.

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http://dx.doi.org/10.1002/ajmg.a.38354DOI Listing
November 2017

Toward a better understanding of enteric gliogenesis.

Neurogenesis (Austin) 2017 2;4(1):e1293958. Epub 2017 Mar 2.

Molecular Genetics of Development Laboratory, Department of Biological Sciences and BioMed Research Center, Faculty of Sciences, University of Quebec at Montreal , Montreal, Quebec, Canada.

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http://dx.doi.org/10.1080/23262133.2017.1293958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358706PMC
March 2017

Upregulation of the Nr2f1-A830082K12Rik gene pair in murine neural crest cells results in a complex phenotype reminiscent of Waardenburg syndrome type 4.

Dis Model Mech 2016 11 1;9(11):1283-1293. Epub 2016 Sep 1.

Molecular Genetics of Development Laboratory, Department of Biological Sciences and BioMed Research Center, University of Quebec at Montreal (UQAM), Montreal, H2X 3Y7, Canada

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http://dx.doi.org/10.1242/dmm.026773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117235PMC
November 2016

Analysis of Enteric Neural Crest Cell Migration Using Heterotopic Grafts of Embryonic Guts.

Bio Protoc 2016 Sep;6(17):1-6

Molecular Genetics of Development Laboratory, Department of Biological Sciences; BioMed Research Center, Faculty of Sciences, University of Quebec at Montreal (UQAM), Montreal, PQ, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026488PMC
http://dx.doi.org/10.21769/bioprotoc.1924DOI Listing
September 2016

Pigmentation-based insertional mutagenesis is a simple and potent screening approach for identifying neurocristopathy-associated genes in mice.

Authors:
Nicolas Pilon

Rare Dis 2016 3;4(1):e1156287. Epub 2016 Mar 3.

Molecular Genetics of Development Laboratory, Department of Biological Sciences and BioMed Research Center, Faculty of Sciences, University of Quebec at Montreal (UQAM), Montreal, Quebec, Canada; UQAM Research Chair on Rare Genetic Diseases, Montreal, Canada.

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http://dx.doi.org/10.1080/21675511.2016.1156287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838316PMC
May 2016

A direct role for murine Cdx proteins in the trunk neural crest gene regulatory network.

Development 2016 Apr 7;143(8):1363-74. Epub 2016 Mar 7.

Molecular Genetics of Development Laboratory, Department of Biological Sciences and BioMed Research Center, University of Quebec at Montreal (UQAM), Montreal H2X 3Y7, Canada

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http://dev.biologists.org/content/develop/143/8/1363.full.pd
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http://dev.biologists.org/lookup/doi/10.1242/dev.132159
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http://dx.doi.org/10.1242/dev.132159DOI Listing
April 2016

Male-biased aganglionic megacolon in the TashT mouse line due to perturbation of silencer elements in a large gene desert of chromosome 10.

PLoS Genet 2015 Mar 18;11(3):e1005093. Epub 2015 Mar 18.

Molecular Genetics of Development Laboratory, Department of Biological Sciences and BioMed Research Center, University of Quebec at Montreal (UQAM), Quebec, Canada.

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http://dx.doi.org/10.1371/journal.pgen.1005093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364714PMC
March 2015

Induction and dorsal restriction of Paired-box 3 (Pax3) gene expression in the caudal neuroectoderm is mediated by integration of multiple pathways on a short neural crest enhancer.

Biochim Biophys Acta 2014 Jul 9;1839(7):546-58. Epub 2014 May 9.

Molecular Genetics of Development Laboratory, Department of Biological Sciences and BioMed Research Center, Faculty of Sciences, University of Quebec at Montreal (UQAM), Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2014.04.023DOI Listing
July 2014

Characterization of a novel transgenic mouse line expressing Cre recombinase under the control of the Cdx2 neural specific enhancer.

Genesis 2013 Nov 30;51(11):777-84. Epub 2013 Aug 30.

Molecular Genetics of Development Laboratory, Department of Biological Sciences and BioMed Research Center, Faculty of Sciences, University of Quebec at Montreal (UQAM), Canada, H2X 3Y7.

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http://dx.doi.org/10.1002/dvg.22421DOI Listing
November 2013

A quantitative cell migration assay for murine enteric neural progenitors.

J Vis Exp 2013 Sep 18(79):e50709. Epub 2013 Sep 18.

Molecular Genetics of Development Laboratory, Biological Sciences, UQAM.

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http://dx.doi.org/10.3791/50709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923887PMC
September 2013

Transgenic mouse analysis of Sry expression during the pre- and peri-implantation stage.

Dev Dyn 2012 Jul 18;241(7):1192-204. Epub 2012 May 18.

Department of Veterinary Biomedicine, Centre de Recherche en Reproduction Animale, Faculty of Veterinary Medicine, University of Montreal, St-Hyacinthe, QC, Canada.

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http://dx.doi.org/10.1002/dvdy.23798DOI Listing
July 2012

Caudal-related homeobox (Cdx) protein-dependent integration of canonical Wnt signaling on paired-box 3 (Pax3) neural crest enhancer.

J Biol Chem 2012 May 28;287(20):16623-35. Epub 2012 Mar 28.

Molecular Genetics of Development, Department of Biological Sciences, and BioMed Research Center, Faculty of Sciences, University of Quebec, Montreal, Quebec H2X 3Y7, Canada.

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http://dx.doi.org/10.1074/jbc.M112.356394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351347PMC
May 2012

An Ebox element in the proximal Gata4 promoter is required for Gata4 expression in vivo.

PLoS One 2011 13;6(12):e29038. Epub 2011 Dec 13.

Department of Biological Sciences and BioMed Research Center, Faculty of Sciences, University of Quebec at Montreal, Quebec, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0029038PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236771PMC
April 2012

Cdx1 and Cdx2 are functionally equivalent in vertebral patterning.

Dev Biol 2009 Jun 27;330(1):114-22. Epub 2009 Mar 27.

Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ydbio.2009.03.016DOI Listing
June 2009

Novel pre- and post-gastrulation expression of Gata4 within cells of the inner cell mass and migratory neural crest cells.

Dev Dyn 2008 Apr;237(4):1133-43

Department of Veterinary Biomedicine, Faculty of Veterinary Medicine, University of Montreal, St-Hyacinthe, QC, Canada.

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http://dx.doi.org/10.1002/dvdy.21496DOI Listing
April 2008

Presumptive pre-Sertoli cells express genes involved in cell proliferation and cell signalling during a critical window in early testis differentiation.

Mol Reprod Dev 2007 Dec;74(12):1491-504

Faculty of Veterinary Medicine, University of Montreal, Saint-Hyacinthe, Quebec, Canada.

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http://dx.doi.org/10.1002/mrd.20722DOI Listing
December 2007

Wnt signaling is a key mediator of Cdx1 expression in vivo.

Development 2007 Jun;134(12):2315-23

Clinical Research Institute of Montreal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1242/dev.001206DOI Listing
June 2007

The proximal Gata4 promoter directs reporter gene expression to sertoli cells during mouse gonadal development.

Biol Reprod 2007 Jan 4;76(1):85-95. Epub 2006 Oct 4.

Ontogeny-Reproduction Research Unit, Centre de Recherche du Centre Hospitalier Universitaire de Québec, Centre de Recherche en Biologie de la Reproduction, Department of Obstetrics and Gynecology, Laval University, Québec City, Québec, Canada G1K 7P4.

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http://dx.doi.org/10.1095/biolreprod.106.055137DOI Listing
January 2007

Human and pig SRY 5' flanking sequences can direct reporter transgene expression to the genital ridge and to migrating neural crest cells.

Dev Dyn 2006 Mar;235(3):623-32

Faculty of Veterinary Medicine, University of Montreal, Saint-Hyacinthe, Quebec, Canada.

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http://dx.doi.org/10.1002/dvdy.20670DOI Listing
March 2006

Cdx4 is a direct target of the canonical Wnt pathway.

Dev Biol 2006 Jan 23;289(1):55-63. Epub 2005 Nov 23.

Institut de Recherches Cliniques de Montréal, Québec, Canada.

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http://dx.doi.org/10.1016/j.ydbio.2005.10.005DOI Listing
January 2006

Cdx1 autoregulation is governed by a novel Cdx1-LEF1 transcription complex.

Mol Cell Biol 2004 Jun;24(11):5028-38

Institut de Recherches Cliniques de Montréal, 110 Avenue des Pins Ouest, Montréal, Québec, Canada H2W 1R7.

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http://dx.doi.org/10.1128/MCB.24.11.5028-5038.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC416402PMC
June 2004

Porcine SRY promoter is a target for steroidogenic factor 1.

Biol Reprod 2003 Apr 31;68(4):1098-106. Epub 2002 Oct 31.

Centre de recherche en reproduction animale, Department of Veterinary Biomedicine, Faculty of Veterinary Medicine, University of Montreal, St-Hyacinthe, Québec, Canada J2S 7C6.

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http://dx.doi.org/10.1095/biolreprod.102.010884DOI Listing
April 2003

The porcine SRY promoter is transactivated within a male genital ridge environment.

Genesis 2002 Aug;33(4):170-80

Faculty of Veterinary Medicine, University of Montreal, Saint Hyacinthe, Québec, Canada.

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http://dx.doi.org/10.1002/gene.10106DOI Listing
August 2002