Nabil F Saba

Nabil F Saba

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Nabil F Saba

Publications by authors named "Nabil F Saba"

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Hsp90B enhances MAST1-mediated cisplatin resistance by protecting MAST1 from proteosomal degradation.

J Clin Invest 2019 Oct;129(10):4110-4123

Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1172/JCI125963DOI Listing
October 2019

Interleukin-6/STAT3 Signaling is Prominent and Associated with Reduced Overall Survival in p16 Negative Oropharyngeal Squamous Cell Carcinoma.

Head Neck Pathol 2019 Sep 6;13(3):304-312. Epub 2018 Sep 6.

Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, 1365 Clifton Rd., NE, Atlanta, GA, 30322, USA.

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http://dx.doi.org/10.1007/s12105-018-0962-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684688PMC
September 2019

Palbociclib and cetuximab in platinum-resistant and in cetuximab-resistant human papillomavirus-unrelated head and neck cancer: a multicentre, multigroup, phase 2 trial.

Lancet Oncol 2019 Sep 24;20(9):1295-1305. Epub 2019 Jul 24.

Division of Medical Oncology, Washington University School of Medicine, St Louis, MO, USA; Alvin J Siteman Cancer Center, Washington University School of Medicine, St Louis, MO, USA.

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http://dx.doi.org/10.1016/S1470-2045(19)30405-XDOI Listing
September 2019

Management of locally recurrent nasopharyngeal carcinoma.

Cancer Treat Rev 2019 Sep 21;79:101890. Epub 2019 Aug 21.

Coordinator of the International Head and Neck Scientific Group, Padua, Italy.

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http://dx.doi.org/10.1016/j.ctrv.2019.101890DOI Listing
September 2019

Racial Disparities, Outcomes, and Surgical Utilization among Hispanics with Esophageal Cancer: A Surveillance, Epidemiology, and End Results Program Database Analysis.

Oncology 2019 20;97(1):49-58. Epub 2019 May 20.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA,

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http://dx.doi.org/10.1159/000499716DOI Listing
July 2019

Prognosis of subglottic carcinoma: Is it really worse?

Head Neck 2019 Feb 26;41(2):511-521. Epub 2018 Jun 26.

Coordinator of the International Head and Neck Scientific Group.

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http://dx.doi.org/10.1002/hed.25172DOI Listing
February 2019

Disparities in Postoperative Therapy for Salivary Gland Adenoid Cystic Carcinomas.

Laryngoscope 2019 02 8;129(2):377-386. Epub 2018 Sep 8.

Department of Radiation Oncology, the Winship Cancer Institute of Emory University, Atlanta, Georgia, U.S.A.

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http://doi.wiley.com/10.1002/lary.27302
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http://dx.doi.org/10.1002/lary.27302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344280PMC
February 2019

Radiographic Imaging Does Not Reliably Predict Macroscopic Extranodal Extension in Human Papilloma Virus-Associated Oropharyngeal Cancer.

ORL J Otorhinolaryngol Relat Spec 2018 3;80(2):85-95. Epub 2018 Jul 3.

Department of Radiology and Imaging Sciences, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1159/000487239DOI Listing
January 2019

Prognostic implications of peritumoral vasculature in head and neck cancer.

Cancer Med 2019 01 21;8(1):147-154. Epub 2018 Dec 21.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia.

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http://doi.wiley.com/10.1002/cam4.1910
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http://dx.doi.org/10.1002/cam4.1910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346230PMC
January 2019

Differential regulation of NF-kB and IRF target genes as they relate to fatigue in patients with head and neck cancer.

Brain Behav Immun 2018 11 11;74:291-295. Epub 2018 Sep 11.

Division of Hematology-Oncology, UCLA AIDS Institute, Molecular Biology Institute, Jonsson Comprehensive Cancer Center, and Norman Cousins Center, UCLA School of Medicine, Los Angeles, CA 90095, United States.

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http://dx.doi.org/10.1016/j.bbi.2018.09.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289813PMC
November 2018

Systemic therapy in non-conventional cancers of the larynx.

Oral Oncol 2018 07 26;82:61-68. Epub 2018 May 26.

Department of Hematology and Medical Oncology, Emory University, 1365 Clifton Road Building C, Atlanta, GA 30322, United States; Winship Cancer Institute, Emory University, 1365 Clifton Road Building C, Atlanta, GA 30322, United States. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2018.05.005DOI Listing
July 2018

Time to Rethink Our Strategy With a Preoperative Intensification Approach.

Authors:
Nabil F Saba

Int J Radiat Oncol Biol Phys 2018 07 20;101(4):762. Epub 2018 Jun 20.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1016/j.ijrobp.2018.03.050DOI Listing
July 2018

A Review of Photodynamic Therapy for Neoplasms of the Head and Neck.

Adv Ther 2018 03 7;35(3):324-340. Epub 2018 Feb 7.

International Head and Neck Scientific Group, Padua, Italy.

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http://dx.doi.org/10.1007/s12325-018-0659-3DOI Listing
March 2018

Deformable Registration of Histological Cancer Margins to Gross Hyperspectral Images using Demons.

Proc SPIE Int Soc Opt Eng 2018 Feb 6;10581. Epub 2018 Mar 6.

Georgia Institute of Technology & Emory University, Wallace H. Coulter Department of Biomedical Engineering, Atlanta, GA, USA.

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http://dx.doi.org/10.1117/12.2293165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138464PMC
February 2018

Resilience and biomarkers of health risk in Black smokers and nonsmokers.

Health Psychol 2017 11 21;36(11):1047-1058. Epub 2017 Aug 21.

Department of Gynecology and Obstetrics, School of Medicine, Emory University.

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http://dx.doi.org/10.1037/hea0000540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653434PMC
November 2017

Refining the predictors of outcome in patients with resectable esophageal cancer.

Authors:
Nabil F Saba

Cancer 2017 11 8;123(21):4097-4098. Epub 2017 Sep 8.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1002/cncr.30952DOI Listing
November 2017

The Impact of Histologic Phenotype in the Treatment of Sinonasal Cancer.

Adv Ther 2017 10 4;34(10):2181-2198. Epub 2017 Sep 4.

Coordinator of the International Head and Neck Scientific Group, Padua, Italy.

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http://dx.doi.org/10.1007/s12325-017-0605-9DOI Listing
October 2017

Head and neck PET/CT therapy response interpretation criteria (Hopkins criteria) - external validation study.

Am J Nucl Med Mol Imaging 2017 1;7(4):174-180. Epub 2017 Sep 1.

Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins School of MedicineBaltimore, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596320PMC
September 2017

Antitumor Activity of 2,9-Di-Sec-Butyl-1,10-Phenanthroline.

PLoS One 2016 29;11(12):e0168450. Epub 2016 Dec 29.

Department of Hematology and Medicinal Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0168450PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199049PMC
July 2017

Pulmonary Sarcomatoid Carcinoma: An Analysis of the National Cancer Data Base.

Clin Lung Cancer 2017 05 7;18(3):286-292. Epub 2016 Dec 7.

Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2016.11.016DOI Listing
May 2017

Association of Cytoplasmic CXCR4 With Loss of Epithelial Marker and Activation of ERK1/2 and AKT Signaling Pathways in Non-Small-Cell Lung Cancer.

Clin Lung Cancer 2017 05 22;18(3):e203-e210. Epub 2016 Dec 22.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2016.12.005DOI Listing
May 2017

Pembrolizumab for Platinum- and Cetuximab-Refractory Head and Neck Cancer: Results From a Single-Arm, Phase II Study.

J Clin Oncol 2017 May 22;35(14):1542-1549. Epub 2017 Mar 22.

Joshua Bauml, University of Pennsylvania, Philadelphia, PA; Tanguy Y. Seiwert, University of Chicago, Chicago, IL; David G. Pfister, Memorial Sloan Kettering Cancer Center, New York, NY; Francis Worden, University of Michigan Comprehensive Cancer Center, Ann Arbor; Ammar Sukari, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Stephen V. Liu, Georgetown University Hospital, Washington, DC; Jill Gilbert, Vanderbilt University School of Medicine, Nashville, TN; Nabil F. Saba, Winship Cancer Institute/Emory University, Atlanta, GA; Jared Weiss, Lineberger Comprehensive Cancer Center at the University of North Carolina, Chapel Hill, NC; Lori Wirth, Massachusetts General Hospital; Robert Haddad, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; Hyunseok Kang, Johns Hopkins University School of Medicine, Baltimore, MD; Michael K. Gibson, University Hospitals Cleveland Medical Center, Cleveland, OH; Erminia Massarelli, The University of Texas MD Anderson Cancer Center, Houston, TX; Steven Powell, Sanford Health, Sioux Falls, SD; and Amy Meister, Xinxin Shu, and Jonathan D. Cheng, Merck & Co., Inc., Kenilworth, NJ.

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http://dx.doi.org/10.1200/JCO.2016.70.1524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946724PMC
May 2017

Association of Lymphovascular Space Invasion With Locoregional Failure and Survival in Patients With Node-Negative Oral Tongue Cancers.

JAMA Otolaryngol Head Neck Surg 2017 04;143(4):382-388

Department of Radiation Oncology, Emory University, Atlanta, Georgia2Winship Cancer Institute at Emory University, Atlanta, Georgia5Department of Otolaryngology, Emory University, Atlanta, Georgia7Department of Medical Oncology, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1001/jamaoto.2016.3795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398912PMC
April 2017

Otorhinolaryngological Toxicities of New Drugs in Oncology.

Adv Ther 2017 04 17;34(4):866-894. Epub 2017 Mar 17.

Department of Drug Development (DITEP), Gustave Roussy Cancer Center and School of Medicine, Paris Sud University, Paris, France.

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http://dx.doi.org/10.1007/s12325-017-0512-0DOI Listing
April 2017

Commentary: Randomized Phase II Study of Duligotuzumab (MEHD7945A) vs. Cetuximab in Squamous Cell Carcinoma of the Head and Neck (MEHGAN Study).

Authors:
Nabil F Saba

Front Oncol 2017 13;7:31. Epub 2017 Mar 13.

Hematology and Medical Oncology, Winship Cancer Institute of Emory University , Atlanta, GA , USA.

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http://dx.doi.org/10.3389/fonc.2017.00031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346538PMC
March 2017

An update on larynx cancer.

CA Cancer J Clin 2017 Jan 29;67(1):31-50. Epub 2016 Nov 29.

Professor and Director of the Head and Neck Medical Oncology Program, Department of Hematology Oncology, Winship Cancer Institute of Emory University, Atlanta, GA.

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http://dx.doi.org/10.3322/caac.21386DOI Listing
January 2017

Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck.

N Engl J Med 2016 11 8;375(19):1856-1867. Epub 2016 Oct 8.

From the University of Pittsburgh Medical Center and Cancer Institute, Pittsburgh (R.L.F.); the Department of Thoracic-Head and Neck Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston (G.B.); Centre Leon Berard, Lyon (J.F.), Centre Antoine Lacassagne, Nice (J.G.), and Institut Gustave Roussy, Villejuif (C.E.) - all in France; Stanford Cancer Institute, Stanford, CA (A.D.C.); Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale Tumori, Milan (L.L.); Institute of Cancer Research-Royal Marsden National Institute for Health Research Biomedical Research Centre, London (K.H.); University Hospital Essen, Essen, Germany (S.K.); University of Chicago, Chicago (E.E.V.); University of Michigan, Ann Arbor (F.W.); Winship Cancer Institute of Emory University, Atlanta (N.F.S.); Hospital Universitario 12 de Octubre, Madrid (L.C.I.D.); Dana-Farber Cancer Institute, Boston (R.H.); Universitätsspital Zurich, Zurich, Switzerland (T.R.); Kobe University Hospital, Kobe (N.K.), and National Cancer Center Hospital East, Kashiwa (M.T.) - both in Japan; Bristol-Myers Squibb, Princeton, NJ (M.M., M.L., W.J.G., J.K., J.W.S.); and Ohio State University, Columbus (M.L.G.).

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http://dx.doi.org/10.1056/NEJMoa1602252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564292PMC
November 2016

The Future Prospects of Immune Therapy in Gastric and Esophageal Adenocarcinoma.

J Clin Med 2016 Nov 14;5(11). Epub 2016 Nov 14.

Department of Hematology and Oncology, Winship Cancer Institute, Emory University, 1365 Clifton Rd NE, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.3390/jcm5110100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126797PMC
November 2016

Is There a Role for PET/CT Parameters to Characterize Benign, Malignant, and Metastatic Parotid Tumors?

AJR Am J Roentgenol 2016 Sep 8;207(3):635-40. Epub 2016 Jun 8.

1 Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Rd NE, Atlanta, GA 30322.

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http://dx.doi.org/10.2214/AJR.15.15590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993674PMC
September 2016

The Challenges of Laryngeal Preservation-Is It the Systemic Agent or the Proper Sequence of Therapy?

JAMA Otolaryngol Head Neck Surg 2016 09;142(9):849-50

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia.

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http://dx.doi.org/10.1001/jamaoto.2016.1229DOI Listing
September 2016

The Evolving and Future Role of Taxanes in Squamous Cell Carcinomas of the Head and Neck: A Review.

JAMA Otolaryngol Head Neck Surg 2016 09;142(9):898-905

Department of Hematology and Medical Oncology, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1001/jamaoto.2016.1238DOI Listing
September 2016

Human papillomavirus oncoprotein E6 upregulates c-Met through p53 downregulation.

Eur J Cancer 2016 09 22;65:21-32. Epub 2016 Jul 22.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002257PMC
September 2016

A novel prediction model for human papillomavirus-associated oropharyngeal squamous cell carcinoma using p16 and subcellular β-catenin expression.

J Oral Pathol Med 2016 Jul 22;45(6):399-408. Epub 2015 Oct 22.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1111/jop.12378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841757PMC
July 2016

ACR Appropriateness criteria® for nasopharyngeal carcinoma.

Head Neck 2016 07 30;38(7):979-86. Epub 2016 Apr 30.

University of California San Francisco, San Francisco, California.

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http://dx.doi.org/10.1002/hed.24423DOI Listing
July 2016

Impact of neck failure on survival in older patients with differentiated thyroid cancer.

Head Neck 2016 06 13;38(6):919-24. Epub 2016 Feb 13.

Department of Radiation Oncology, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1002/hed.24385DOI Listing
June 2016

Mannitol to prevent cisplatin-induced nephrotoxicity in patients with squamous cell cancer of the head and neck (SCCHN) receiving concurrent therapy.

Support Care Cancer 2016 Apr 7;24(4):1789-93. Epub 2015 Oct 7.

Department of Hematology and Medical Oncology, School of Medicine, Emory University, Atlanta, GA, USA.

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http://link.springer.com/10.1007/s00520-015-2978-0
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http://dx.doi.org/10.1007/s00520-015-2978-0DOI Listing
April 2016

Complete Remission of Acute Myeloid Leukemia following Cisplatin Based Concurrent Therapy with Radiation for Squamous Cell Laryngeal Cancer.

Case Rep Hematol 2016 3;2016:8581421. Epub 2016 Apr 3.

Winship Cancer Institute of Emory University, Atlanta, GA 30322, USA; Department of Hematology and Medical Oncology, Emory University, Atlanta, GA 30322, USA.

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http://www.hindawi.com/journals/crihem/2016/8581421/
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http://dx.doi.org/10.1155/2016/8581421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834160PMC
April 2016

Targeting epidermal growth factor receptor for head and neck squamous cell carcinoma: still lost in translation?

Ann Transl Med 2016 Feb;4(4):80

1 Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA ; 2 Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.3978/j.issn.2305-5839.2016.01.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779778PMC
February 2016

Oral Cavity Cancer: Risk Factors, Pathology, and Management.

Oncology 2015 17;89(4):187-95. Epub 2015 Jun 17.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Ga., USA.

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http://dx.doi.org/10.1159/000398801DOI Listing
December 2015

Targeting HER (ERBB) signaling in head and neck cancer: An essential update.

Mol Aspects Med 2015 Nov 7;45:74-86. Epub 2015 Jul 7.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, 1365-C Clifton Road, NE, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2015.07.001DOI Listing
November 2015

Heregulin and HER3 are prognostic biomarkers in oropharyngeal squamous cell carcinoma.

Cancer 2015 Oct 20;121(20):3600-11. Epub 2015 Jul 20.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1002/cncr.29549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592409PMC
October 2015

Bevacizumab in Combination with Taxane versus Non-Taxane Containing Regimens for Advanced/Metastatic Nonsquamous Non-Small-Cell Lung Cancer: A Systematic Review.

J Thorac Oncol 2015 Aug;10(8):1142-7

*Department of Hematology and Medical Oncology, Emory University, Atlanta, Georgia; †Winship Cancer Institute of Emory University, Atlanta, Georgia; ‡Biostatistics and Bioinformatics Research Center, Cedars-Sinai Medical Center, Los Angeles, California; §Department of Biostatistics and Bioinformatics, Emory University, Atlanta, Georgia; and ‖Penn State Hershey Cancer Institute, Hershey, Pennsylvania.

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http://dx.doi.org/10.1097/JTO.0000000000000572DOI Listing
August 2015

Combination of erlotinib and EGCG induces apoptosis of head and neck cancers through posttranscriptional regulation of Bim and Bcl-2.

Apoptosis 2015 Jul;20(7):986-95

Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, 30322, USA.

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http://dx.doi.org/10.1007/s10495-015-1126-0DOI Listing
July 2015

Racial disparities in squamous cell carcinoma of the oral tongue among women: a SEER data analysis.

Oral Oncol 2015 Jun 10;51(6):586-92. Epub 2015 Apr 10.

Department of Hematology and Medical Oncology, The Winship Cancer Institute of Emory University, United States. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2015.03.010DOI Listing
June 2015