Matthias Schwab

Matthias Schwab

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Matthias Schwab

Publications by authors named "Matthias Schwab"

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Development of the PGx-Passport: A Panel of Actionable Germline Genetic Variants for Pre-Emptive Pharmacogenetic Testing.

Clin Pharmacol Ther 2019 Oct 12;106(4):866-873. Epub 2019 Jun 12.

Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/cpt.1489DOI Listing
October 2019

Variability and heritability of thiamine pharmacokinetics with focus on OCT1 effects on membrane transport and pharmacokinetics in humans.

Clin Pharmacol Ther 2019 Oct 8. Epub 2019 Oct 8.

Department of Clinical Pharmacology, University Medical Center, Georg August University, D-37075, Goettingen, Germany.

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http://dx.doi.org/10.1002/cpt.1666DOI Listing
October 2019

Impact of NUDT15 genetics on severe thiopurine-related hematotoxicity in patients with European ancestry.

Genet Med 2019 Sep 7;21(9):2145-2150. Epub 2019 Feb 7.

Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.

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http://dx.doi.org/10.1038/s41436-019-0448-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752748PMC
September 2019

Tamoxifen Pharmacogenetics and Metabolism: The Same Is Not the Same.

J Clin Oncol 2019 Aug 18;37(22):1981-1982. Epub 2019 Jun 18.

Hiltrud Brauch, PhD, Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany, University of Tübingen, Tübingen, Germany, and German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany; Werner Schroth, PhD and Thomas Mürdter, PhD, Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany, and University of Tübingen, Tübingen, Germany; and Matthias Schwab, MD, Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany, University of Tübingen, Tübingen, Germany, and German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1200/JCO.19.00507DOI Listing
August 2019

Identification of novel agonists by high-throughput screening and molecular modelling of human constitutive androstane receptor isoform 3.

Arch Toxicol 2019 Aug 16;93(8):2247-2264. Epub 2019 Jul 16.

Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Auerbachstrasse 112, 70376, Stuttgart, Germany.

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http://dx.doi.org/10.1007/s00204-019-02495-6DOI Listing
August 2019

Metabolic and Lipidomic Reprogramming in Renal Cell Carcinoma Subtypes Reflects Regions of Tumor Origin.

Eur Urol Focus 2019 Jul 13;5(4):608-618. Epub 2018 Feb 13.

Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tuebingen, Tuebingen, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Clinical Pharmacology, University Hospital Tuebingen, Tuebingen, Germany; Department of Pharmacy and Biochemistry, University of Tuebingen, Tuebingen, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S24054569183001
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http://dx.doi.org/10.1016/j.euf.2018.01.016DOI Listing
July 2019

Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1.

Clin Pharmacol Ther 2019 Jul 27. Epub 2019 Jul 27.

Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.

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http://dx.doi.org/10.1002/cpt.1588DOI Listing
July 2019

Late-life brain perfusion after prenatal famine exposure.

Neurobiol Aging 2019 Jul 8;82:1-9. Epub 2019 Jul 8.

Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam UMC, the Netherlands; Department of Obstetrics and Gynaecology, Amsterdam UMC, the Netherlands.

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.06.012DOI Listing
July 2019

A Clinical Drug-Drug Interaction Study Assessing a Novel Drug Transporter Phenotyping Cocktail With Adefovir, Sitagliptin, Metformin, Pitavastatin, and Digoxin.

Clin Pharmacol Ther 2019 Jun 27. Epub 2019 Jun 27.

University of Cologne, Faculty of Medicine and University Hospital Cologne, Center for Pharmacology, Department I of Pharmacology, Cologne, Germany.

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http://dx.doi.org/10.1002/cpt.1564DOI Listing
June 2019

Pharmacogene Variation Consortium Gene Introduction: NUDT15.

Clin Pharmacol Ther 2019 May 4;105(5):1091-1094. Epub 2018 Dec 4.

School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.

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http://dx.doi.org/10.1002/cpt.1268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465081PMC
May 2019

: a detailed medical description of sleep disordered breathing and its consequences by Georg Grau in 1688.

Eur Respir J 2019 May 9;53(5). Epub 2019 May 9.

Centre for Applied Disease Prevention, Dresden, Germany.

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http://dx.doi.org/10.1183/13993003.01799-2018DOI Listing
May 2019

Molecular signature of human bone marrow-derived mesenchymal stromal cell subsets.

Sci Rep 2019 Feb 11;9(1):1774. Epub 2019 Feb 11.

University Hospital for Children and Adolescents, Division for Stem Cell Transplantation and Immunology, Frankfurt am Main, Germany.

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http://www.nature.com/articles/s41598-019-38517-7
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http://dx.doi.org/10.1038/s41598-019-38517-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370815PMC
February 2019

Ten years of Genome Medicine.

Genome Med 2019 02 15;11(1). Epub 2019 Feb 15.

Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Auerbachstraße, 70376, Stuttgart, Germany.

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http://dx.doi.org/10.1186/s13073-019-0618-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376775PMC
February 2019

A Web-based survey among adults aged 40-54 years was time effective and yielded stable response patterns.

J Clin Epidemiol 2019 Jan 6;105:10-18. Epub 2018 Sep 6.

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany; German Cancer Consortium (DKTK), DKFZ, Heidelberg, Germany; Division of Preventive Oncology, DKFZ and National Center of Tumor Diseases (NCT), Heidelberg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S08954356183041
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http://dx.doi.org/10.1016/j.jclinepi.2018.08.021DOI Listing
January 2019

Very Low Frequency Heart Rate Variability Predicts the Development of Post-Stroke Infections.

Transl Stroke Res 2019 Jan 7. Epub 2019 Jan 7.

Hans Berger Department of Neurology, Jena University Hospital, Am Klinikum 1, 07747, Jena, Germany.

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http://link.springer.com/10.1007/s12975-018-0684-1
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http://dx.doi.org/10.1007/s12975-018-0684-1DOI Listing
January 2019

Systematic Review of Variations in Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Peritoneal Metastasis from Colorectal Cancer.

J Clin Med 2018 Dec 19;7(12). Epub 2018 Dec 19.

Department of General, Visceral and Transplant Surgery, University Hospital Tübingen, Hoppe-Seyler-Str. 3, D-72076 Tübingen, Germany.

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http://dx.doi.org/10.3390/jcm7120567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306814PMC
December 2018

Potential Role of CXCR4 Targeting in the Context of Radiotherapy and Immunotherapy of Cancer.

Front Immunol 2018 21;9:3018. Epub 2018 Dec 21.

Department of Radiation Oncology, University Hospital Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.3389/fimmu.2018.03018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308162PMC
December 2018

Rapid increases in nitrogen oxides are associated with acute myocardial infarction: A case-crossover study.

Eur J Prev Cardiol 2018 11 15;25(16):1707-1716. Epub 2018 Feb 15.

1 Hans Berger Department of Neurology, University Hospital Jena, Germany.

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http://dx.doi.org/10.1177/2047487318755804DOI Listing
November 2018

Apheresis therapies for NMOSD attacks: A retrospective study of 207 therapeutic interventions.

Neurol Neuroimmunol Neuroinflamm 2018 Nov 26;5(6):e504. Epub 2018 Sep 26.

Department of Neurology (I.K., A.G., K.H.), St. Josef Hospital, Ruhr University Bochum; Marianne-Strauß-Klinik (I.K.), Behandlungszentrum Kempfenhausen für Multiple Sklerose Kranke, Berg; NeuroCure Clinical Research Center and Experimental and Clinical Research Center (N.B., F. Pache), Charité Universitätsmedizin Berlin, and Max Delbrueck Center for Molecular Medicine, Berlin; Department of Neurology (K.F., J.F.), Asklepios Fachklinikum Teupitz; CRO Sostana GmbH and Charité Universitätsmedizin Berlin (K.-D.W.); Department of Neurology and Clinical and Experimental Multiple Sclerosis Research Center (F.Pache, K.R.), Charité Universitätsmedizin Berlin; Institute of Clinical Neuroimmunology (J.H., T.K.), Ludwig Maximilians University, Munich; Department of Neurology (O.A., H.-P.H., M.R.), Medical Faculty, Heinrich Heine University Düsseldorf; Department of Neurology (C.G., M. Schwab), Jena University Hospital; Department of Neurology (C.K.), University Hospital Essen; Department of Neurology (A.B.), Klinikum rechts der Isar, Technische Universität München, Munich; Department of Neurology (B.H.), Klinikum rechts der Isar, Technische Universität München and Munich Cluster for Systems Neurology (SyNergy); Department of Neurology (K.A.), University Hospital Regensburg; Institute of Neuroimmunology and MS (INIMS) and Department of Neurology (J.-P.S.), University Medical Centre Hamburg-Eppendorf, HamburgKlinik und Poliklinik für Neurologie (S.S.), Universitätsklinikum Hamburg-Eppendorf; Clinical Neuroimmunology and Neurochemistry (M. Stangel), Department of Neurology, Hannover Medical School; Department of Neurology (F.L., H.T.), University of Ulm; Fachklinik für Neurologie Dietenbronn (H.T.), Akademisches Krankenhaus der Universität Ulm, Schwendi; Department of Neurology (C.M.), Goethe University Frankfurt; Department of Neurology & Stroke (M.K., L.Z., U. Ziemann), and Hertie-Institute for Clinical Brain Research, University of Tübingen; Department of Neurology (R.L.), Friedrich-Alexander University Erlangen-Nuremberg; Department of Neurology and Neurological Intensive Care (M.M.), Isar-Amper-Clinic, Munich-East, Haar; Department of Neurology (F.T.B.), University of Leipzig; Department of Neurology (U. Hofstadt-van Oy), Klinikum Westfalen, Dortmund; Department of Neurology (O.N.), SRH Krankenhaus Sigmaringen; Neuroimmunological Section (U. Zettl), Department of Neurology, University of Rostock; Molecular Neuroimmunology Group (B.W., S.J.), Department of Neurology, University of Heidelberg; NeuroCure Clinical Research Center (F. Paul), Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, and Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité-Universitätsmedizin Berlin; and Department of Neurology (C.T.), Hannover Medical School, Germany.

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http://dx.doi.org/10.1212/NXI.0000000000000504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192689PMC
November 2018

The fruit fly Drosophila melanogaster as an innovative preclinical ADME model for solute carrier membrane transporters, with consequences for pharmacology and drug therapy.

Drug Discov Today 2018 10 8;23(10):1746-1760. Epub 2018 Jun 8.

Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tübingen, Tübingen, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S13596446183008
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http://dx.doi.org/10.1016/j.drudis.2018.06.002DOI Listing
October 2018

Simultaneous Extraction of RNA and Metabolites from Single Kidney Tissue Specimens for Combined Transcriptomic and Metabolomic Profiling.

J Proteome Res 2018 09 23;17(9):3039-3049. Epub 2018 Aug 23.

Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology , Stuttgart , Germany and University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1021/acs.jproteome.8b00199DOI Listing
September 2018

Clinical and Functional Relevance of the Monocarboxylate Transporter Family in Disease Pathophysiology and Drug Therapy.

Clin Transl Sci 2018 07 16;11(4):352-364. Epub 2018 Apr 16.

Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.

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http://dx.doi.org/10.1111/cts.12551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039204PMC
July 2018

Study protocol of the RaPS study: novel risk adapted prevention strategies for people with a family history of colorectal cancer.

BMC Cancer 2018 Jul 6;18(1):720. Epub 2018 Jul 6.

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1186/s12885-018-4646-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034214PMC
July 2018

Influence of Variants on ova Treatment Outcome in Crohn's Disease.

Front Pharmacol 2018 16;9:764. Epub 2018 Jul 16.

Department of Internal Medicine I, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.3389/fphar.2018.00764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054957PMC
July 2018

Premature brain aging in humans exposed to maternal nutrient restriction during early gestation.

Neuroimage 2018 06 23;173:460-471. Epub 2017 Oct 23.

Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.neuroimage.2017.10.047DOI Listing
June 2018

Sex-dimorphic acceleration of pericardial, subcutaneous, and plasma lipid increase in offspring of poorly nourished baboons.

Int J Obes (Lond) 2018 06 30;42(5):1092-1096. Epub 2018 Jan 30.

Department of Radiology and Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

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http://dx.doi.org/10.1038/s41366-018-0008-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019612PMC
June 2018

Reply to the letter 'Is a rapid increase in nitrogen oxides really associated with an acute myocardial infarction?'

Eur J Prev Cardiol 2018 06 29;25(9):997-998. Epub 2018 Mar 29.

Hans Berger Department of Neurology, University Hospital Jena, Germany.

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http://dx.doi.org/10.1177/2047487318768324DOI Listing
June 2018

Variants of PEAR1 Are Associated With Outcome in Patients With ACS and Stable CAD Undergoing PCI.

Front Pharmacol 2018 15;9:490. Epub 2018 May 15.

Department of Cardiology and Cardiovascular Medicine, University Hospital of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.3389/fphar.2018.00490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962768PMC
May 2018

Systemic regulation of bilirubin homeostasis: Potential benefits of hyperbilirubinemia.

Hepatology 2018 04 2;67(4):1609-1619. Epub 2018 Mar 2.

Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.

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http://dx.doi.org/10.1002/hep.29599DOI Listing
April 2018

Identification of approved drugs as potent inhibitors of pregnane X receptor activation with differential receptor interaction profiles.

Arch Toxicol 2018 Apr 22;92(4):1435-1451. Epub 2018 Jan 22.

Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Schnackenburgallee 114, 22525, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00204-018-2165-4DOI Listing
April 2018

Adverse Drug Reactions (ADR) and Emergencies.

Dtsch Arztebl Int 2018 04;115(15):251-258

Research Department, Federal Institute for Drugs and Medical Devices, Bonn; Central Emergency Department, Hospital Fürth; Internal Medicine Emergency Department, Ulm University Medical Center; Interdisciplinary Emergency Department (INZ), University Hospital of Bonn; Dr. Margarete Fischer Bosch Institute of Clinical Pharmacology (IKP), Stuttgart; Institute for Clinical Pharmacology and Institute for Pharmacy and Biochemistry, University Hospital Tübingen; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ) Heidelberg; Center for Translational Medicine, Medical Faculty, University Bonn.

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http://dx.doi.org/10.3238/arztebl.2018.0251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949373PMC
April 2018

The formation of estrogen-like tamoxifen metabolites and their influence on enzyme activity and gene expression of ADME genes.

Arch Toxicol 2018 Mar 28;92(3):1099-1112. Epub 2017 Dec 28.

Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology and University of Tübingen, Auerbachstr. 112, 70376, Stuttgart, Germany.

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http://dx.doi.org/10.1007/s00204-017-2147-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866846PMC
March 2018

Long-Term Effects of Inhaled Budesonide for Bronchopulmonary Dysplasia.

N Engl J Med 2018 01;378(2):148-157

From the Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich (D.B.), and the Division of Pediatric Pharmacology and Pharmacometrics, University of Basel Children's Hospital, Basel (J.N.A.) - both in Switzerland; Ziv Medical Center, Faculty of Medicine in the Galilee, Bar-Ilan University, Ramat Gan, Israel (E.S.S.); the Department of Children and Adolescents, Oulu University Hospital, and PEDEGO Research Unit, Medical Research Center Oulu, University of Oulu, Oulu, Finland (M.H.); Assistance Publique-Hôpitaux de Paris, Département Hospitalo-Universitaire Risques et Grossesse, Université Paris Descartes, Hôpital Cochin, Service de Médecine et Réanimation Néonatales de Port-Royal, Paris (P.-H.J.); Charles University, General Faculty Hospital and 1st Faculty of Medicine in Prague, Prague, Czech Republic (R.P.); Polytechnical University of Marche, Salesi Children's Hospital, Ancona, Italy (V.C.); Institute for Clinical Epidemiology and Applied Biometry (C.M.), University Children's Hospital Tübingen, Center for Pediatric Clinical Studies (C.E.), Department of Neonatology, University Children's Hospital (A.K., K.K., C.F.P.), and Department of Clinical Pharmacology and Department of Pharmacy and Biochemistry, University Hospital and University of Tübingen (M.S.), Tübingen, and Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart (M.S.) - all in Germany; Intensive Care and Department of Pediatric Surgery, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands (J.N.A.); the Division of Clinical Pharmacology, Children's National Health System, Washington, DC (J.N.A.); and the Department of Child Health at Queen's University Belfast, Institute of Clinical Science, Belfast, United Kingdom (H.L.H.).

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http://dx.doi.org/10.1056/NEJMoa1708831DOI Listing
January 2018

Neuroprotective, Neurogenic, and Amyloid Beta Reducing Effect of a Novel Alpha 2-Adrenoblocker, Mesedin, on Astroglia and Neuronal Progenitors upon Hypoxia and Glutamate Exposure.

Int J Mol Sci 2017 Dec 21;19(1). Epub 2017 Dec 21.

Department of Clinical Pharmacology, Institute of Clinical and Experimental Pharmacology and Toxicology, University Hospital of Tübingen, Auf der Morgenstelle 8, D-72076 Tübingen, Germany.

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http://www.mdpi.com/1422-0067/19/1/9
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http://dx.doi.org/10.3390/ijms19010009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795961PMC
December 2017

Genetic variation in human drug-related genes.

Genome Med 2017 12 22;9(1):117. Epub 2017 Dec 22.

Department of Systems Biology, Harvard Medical School, Boston, 02115, Massachusetts, USA.

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http://dx.doi.org/10.1186/s13073-017-0502-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740940PMC
December 2017

Information processing deficits as a driving force for memory impairment in MS: A cross--sectional study of memory functions and MRI in early and late stage MS.

Mult Scler Relat Disord 2017 Nov 25;18:119-127. Epub 2017 Sep 25.

Heinrich Heine University, Medical Faculty, Cognitive Psychology and Methodology, Moorenstraße 5, 40225 Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2017.09.026DOI Listing
November 2017

Fetal Sheep Mesenteric Resistance Arteries: Functional and Structural Maturation.

J Vasc Res 2017 16;54(5):259-271. Epub 2017 Aug 16.

Hans Berger Department of Neurology, Jena University Hospital, Jena, Germany.

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http://dx.doi.org/10.1159/000477629DOI Listing
October 2017

Evidence for a pharmacokinetic interaction between eslicarbazepine and rosuvastatin: Potential effects on xenobiotic transporters.

Epilepsy Res 2017 09 18;135:64-70. Epub 2017 May 18.

Translational Medicine and Early Development, Sunovion Pharmaceuticals, Inc., 84 Waterford Drive, Marlborough, MA 01752, USA. Electronic address:

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http://dx.doi.org/10.1016/j.eplepsyres.2017.05.005DOI Listing
September 2017

Pharmacokinetics and pharmacodynamics of thiopurines in an in vitro model of human hepatocytes: Insights from an innovative mass spectrometry assay.

Chem Biol Interact 2017 Sep 12;275:189-195. Epub 2017 Aug 12.

Department of Medical, Surgical and Health Sciences, University of Trieste, I-34127 Trieste, Italy; Institute for Maternal and Child Health I.R.C.C.S. Burlo Garofolo, I-34137 Trieste, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S00092797173025
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http://dx.doi.org/10.1016/j.cbi.2017.08.009DOI Listing
September 2017

Ligand-dependent and -independent regulation of human hepatic sphingomyelin phosphodiesterase acid-like 3A expression by pregnane X receptor and crosstalk with liver X receptor.

Biochem Pharmacol 2017 07 13;136:122-135. Epub 2017 Apr 13.

Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology Stuttgart, Germany and University of Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2017.04.013DOI Listing
July 2017

Maternal nutrient restriction during pregnancy and lactation leads to impaired right ventricular function in young adult baboons.

J Physiol 2017 07 18;595(13):4245-4260. Epub 2017 May 18.

Department of Radiology and Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

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http://dx.doi.org/10.1113/JP273928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491873PMC
July 2017

Weather as a risk factor for epileptic seizures: A case-crossover study.

Epilepsia 2017 07 8;58(7):1287-1295. Epub 2017 May 8.

Hans Berger Department of Neurology, Jena University Hospital, Jena, Germany.

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http://dx.doi.org/10.1111/epi.13776DOI Listing
July 2017

Human pregnane X receptor is activated by dibenzazepine carbamate-based inhibitors of constitutive androstane receptor.

Arch Toxicol 2017 Jun 13;91(6):2375-2390. Epub 2017 Mar 13.

Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology Stuttgart and University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1007/s00204-017-1948-3DOI Listing
June 2017

Comment on "Epigenetic activation of the drug transporter OCT2 sensitizes renal cell carcinoma to oxaliplatin".

Sci Transl Med 2017 05;9(391)

Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology and University of Tuebingen, Auerbachstr.112, 70376 Stuttgart, Germany.

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http://dx.doi.org/10.1126/scitranslmed.aal2439DOI Listing
May 2017

The importance of drug transporter characterization to precision medicine.

Expert Opin Drug Metab Toxicol 2017 04 9;13(4):361-365. Epub 2017 Feb 9.

a Dr. Margarete Fischer-Bosch - Institute of Clinical Pharmacology , Stuttgart , Germany.

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http://dx.doi.org/10.1080/17425255.2017.1290083DOI Listing
April 2017

Premature Brain Aging in Baboons Resulting from Moderate Fetal Undernutrition.

Front Aging Neurosci 2017 11;9:92. Epub 2017 Apr 11.

Texas Pregnancy and Life Course Health Research Center, Southwest National Primate Research Center, Texas Biomedical Research InstituteSan Antonio, TX, USA.

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http://dx.doi.org/10.3389/fnagi.2017.00092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386978PMC
April 2017

Transfer of maternal psychosocial stress to the fetus.

Neurosci Biobehav Rev 2017 Feb 22. Epub 2017 Feb 22.

Hans Berger Department of Neurology, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neubiorev.2017.02.019DOI Listing
February 2017

Open letter on access to the BIA 10-2474 clinical trial data.

Lancet 2017 01 10;389(10065):156. Epub 2016 Dec 10.

Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; Department of Clinical Pharmacology, University Hospital, Tuebingen, Germany.

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http://dx.doi.org/10.1016/S0140-6736(16)32515-6DOI Listing
January 2017

Effects of the Selective α5-GABAAR Antagonist S44819 on Excitability in the Human Brain: A TMS-EMG and TMS-EEG Phase I Study.

J Neurosci 2016 12;36(49):12312-12320

Department of Neurology and Stroke, and Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany,

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http://dx.doi.org/10.1523/JNEUROSCI.1689-16.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601976PMC
December 2016