Martin Yaffe

Martin Yaffe

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Martin Yaffe

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Investigating the feasibility of stratified breast cancer screening using a masking risk predictor.

Breast Cancer Res 2019 08 9;21(1):91. Epub 2019 Aug 9.

Physical Sciences, Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, Ontario, M4N 3M5, Canada.

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http://dx.doi.org/10.1186/s13058-019-1179-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688203PMC
August 2019

A Case-Control Study to Add Volumetric or Clinical Mammographic Density into the Tyrer-Cuzick Breast Cancer Risk Model.

J Breast Imaging 2019 Jun 11;1(2):99-106. Epub 2019 May 11.

University of Virginia, Department of Radiology and Medical Imaging, University of Virginia Health Sciences Center, Charlottesville, VA.

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http://dx.doi.org/10.1093/jbi/wbz006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690422PMC
June 2019

Prediction of Cancer Masking in Screening Mammography Using Density and Textural Features.

Acad Radiol 2019 May 10;26(5):608-619. Epub 2018 Aug 10.

Physical Sciences, Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.acra.2018.06.011DOI Listing
May 2019

RE: A Methodological Issue in Prediction of Cancer Masking in Screening Mammography Using Density and Textural Features - Authors' Response.

Acad Radiol 2019 May 31;26(5):e78. Epub 2019 Jan 31.

Physical Sciences, Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.acra.2018.11.022DOI Listing
May 2019

Emergence of "Big Data" and Its Potential and Current Limitations in Medical Imaging.

Authors:
Martin J Yaffe

Semin Nucl Med 2019 03 6;49(2):94-104. Epub 2018 Dec 6.

Physical Sciences Program, Sunnybrook Health Sciences Centre and The University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1053/j.semnuclmed.2018.11.010DOI Listing
March 2019

The effect of mammography screening regimen on incidence-based breast cancer mortality.

J Med Screen 2018 12 26;25(4):197-204. Epub 2018 Jul 26.

10 Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, USA.

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http://dx.doi.org/10.1177/0969141318780152DOI Listing
December 2018

[18F]-Fluorodeoxyglucose PET/CT imaging as a marker of carotid plaque inflammation: Comparison to immunohistology and relationship to acuity of events.

Int J Cardiol 2018 Nov 2;271:378-386. Epub 2018 Jun 2.

Molecular Function and Imaging Program and the National Cardiac PET Centre, Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Department of Radiology, University of Ottawa and The Ottawa Hospital, Ottawa, Ontario, Canada; Division of Nuclear Medicine, Department of Medicine, University of Ottawa and The Ottawa Hospital, Ottawa, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2018.05.057DOI Listing
November 2018

Towards improving accuracy, effectiveness, and efficiency in breast cancer screening.

Authors:
Martin J Yaffe

Lancet Oncol 2018 11 12;19(11):1426-1427. Epub 2018 Oct 12.

Physical Sciences Platform, Sunnybrook Research Institute, Department of Medical Biophysics, and Department of Medical Imaging, University of Toronto, Toronto, ON, Canada; Imaging Research Program, Ontario Institute for Cancer Research, Toronto M4N 3M5, ON, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183058
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http://dx.doi.org/10.1016/S1470-2045(18)30589-8DOI Listing
November 2018

Serum osteoprotegerin levels and mammographic density among high-risk women.

Cancer Causes Control 2018 06 20;29(6):507-517. Epub 2018 Apr 20.

Women's College Research Institute, Women's College Hospital, 76 Grenville St., 6th Floor, Toronto, ON, M5S 1B2, Canada.

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http://dx.doi.org/10.1007/s10552-018-1035-yDOI Listing
June 2018

The origins of breast cancer associated with mammographic density: a testable biological hypothesis.

Breast Cancer Res 2018 03 7;20(1):17. Epub 2018 Mar 7.

Genetics and Genome Biology, Hospital for Sick Children Research Institute, Toronto, ON, Canada.

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http://dx.doi.org/10.1186/s13058-018-0941-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842598PMC
March 2018

Cost-effectiveness of mammography from a publicly funded health care system perspective.

CMAJ Open 2018 Feb;6(1):E77-E86

Affiliations: Sunnybrook Research Institute (Mittmann), Sunnybrook Health Sciences Centre; Department of Pharmacology and Toxicology (Mittmann), University of Toronto, Toronto, Ont.; Department of Population Medicine (Stout), Harvard Medical School and Harvard Pilgrim Health Care, Boston, Mass.; Dartmouth Institute for Health Policy and Clinical Practice (Tosteson), Geisel School of Medicine, Dartmouth College, Hanover, NH; Department of Population Health Sciences and Carbone Cancer Center (Trentham-Dietz, Alagoz); Department of Industrial and Systems Engineering (Alagoz), University of Wisconsin-Madison, Madison, Wisc.; Physical Sciences Program (Yaffe), Sunnybrook Research Institute, Sunnybrook Health Sciences Centre; Departments of Medical Biophysics and Medical Imaging (Yaffe), University of Toronto, Toronto, Ont.

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http://dx.doi.org/10.9778/cmajo.20170106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878949PMC
February 2018

A Randomized Double-Blind Placebo-Controlled Trial of the Effect of Vitamin D Supplementation on Breast Density in Premenopausal Women.

Cancer Epidemiol Biomarkers Prev 2017 08 17;26(8):1233-1241. Epub 2017 May 17.

Centre de Recherche du CHU de Québec-Université Laval, Québec, Canada.

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http://dx.doi.org/10.1158/1055-9965.EPI-17-0249DOI Listing
August 2017

What Do Women Know About Breast Density? Results From a Population Survey of Virginia Women.

J Am Coll Radiol 2017 Jan 24;14(1):34-44. Epub 2016 Sep 24.

Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia. Electronic address:

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http://dx.doi.org/10.1016/j.jacr.2016.07.003DOI Listing
January 2017

Reducing radiation doses for breast tomosynthesis?

Authors:
Martin J Yaffe

Lancet Oncol 2016 08 23;17(8):1027-1029. Epub 2016 Jun 23.

Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, 2075 Bayview Ave, Toronto, ON M4N 3M5, Canada. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(16)30155-3DOI Listing
August 2016

Technical Note: Robust measurement of the slice-sensitivity profile in breast tomosynthesis.

Med Phys 2016 Aug;43(8):4803

Departments of Medical Imaging and Medical Biophysics, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada and Physical Sciences Platform, Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada.

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http://dx.doi.org/10.1118/1.4959539DOI Listing
August 2016

Ki-67 Membranous Staining: Biologically Relevant or an Artifact of Multiplexed Immunofluorescent Staining.

Appl Immunohistochem Mol Morphol 2016 07;24(6):447-52

*Physical Sciences, Sunnybrook Research Institute §Department of Anatomic Pathology, Sunnybrook Health Sciences Centre Departments of ‡Laboratory Medicine and Pathobiology ∥Departments of Medical Biophysics and Medical Imaging, Faculty of Medicine, University of Toronto, Toronto, ON, Canada †Diagnostics and Biomedical Technologies, Global Research Center, General Electric Company, Niskayuna, NY.

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http://dx.doi.org/10.1097/PAI.0000000000000202DOI Listing
July 2016

Whole-mount pathology of breast lumpectomy specimens improves detection of tumour margins and focality.

Histopathology 2016 Jul 19;69(1):35-44. Epub 2016 Jan 19.

Physical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/his.12912DOI Listing
July 2016

Response to: "[Miller's] Response to: 'Beyond the mammography debate: a moderate perspective'".

Authors:
Martin J Yaffe

Curr Oncol 2016 Jun 9;23(3):e324-6. Epub 2016 Jun 9.

Imaging Research, Sunnybrook Research Institute, Departments of Medical Biophysics and Medical Imaging, University of Toronto, Smarter Imaging Program, Ontario Institute for Cancer Research, Toronto, Ontario.

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http://dx.doi.org/10.3747/co.23.3113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900854PMC
June 2016

Case-control study of mammographic density and breast cancer risk using processed digital mammograms.

Breast Cancer Res 2016 05 21;18(1):53. Epub 2016 May 21.

Department of Health Research and Policy, Division of Epidemiology, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1186/s13058-016-0715-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875652PMC
May 2016

Quantifying masking in clinical mammograms via local detectability of simulated lesions.

Med Phys 2016 Mar;43(3):1249-58

Physical Sciences, Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada and Department of Medical Biophysics, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada.

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http://dx.doi.org/10.1118/1.4941307DOI Listing
March 2016

Digital Compared with Screen-Film Mammography: Measures of Diagnostic Accuracy among Women Screened in the Ontario Breast Screening Program.

Radiology 2016 Feb 2;278(2):365-73. Epub 2015 Sep 2.

From the Department of Prevention and Cancer Control, Cancer Care Ontario, 505 University Ave, Toronto, ON, Canada M5G 1X3 (M.V.P., D.M., R.S., V.M., P.B., H.J., A.M.C.); Dalla Lana School of Public Health, University of Toronto, Toronto, Ont, Canada (P.B., A.M.C.); Campbell Family Institute for Breast Cancer Research, University Health Network, Toronto, Ont, Canada (S.J.D.); and Department of Physical Sciences, Sunnybrook Health Sciences Centre, Toronto, Ont, Canada (M.J.Y.).

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http://dx.doi.org/10.1148/radiol.2015150733DOI Listing
February 2016

Adjunctive ultrasonography in breast cancer screening.

Lancet 2016 Jan 5;387(10016):313-314. Epub 2015 Nov 5.

Department of Medical Imaging, Sunnybrook Health Sciences Centre and University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/S0140-6736(15)00787-4DOI Listing
January 2016

Modelling mammography screening for breast cancer in the Canadian context: Modification and testing of a microsimulation model.

Health Rep 2015 Dec;26(12):3-8

Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871249PMC
December 2015

Clinical outcomes of modelling mammography screening strategies.

Health Rep 2015 Dec;26(12):9-15

Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869692PMC
December 2015

Total cost-effectiveness of mammography screening strategies.

Health Rep 2015 Dec;26(12):16-25

Physical Sciences Program, Sunnybrook Research Institute; Departments of Medical Biophysics and Medical Imaging, University of Toronto.

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http://search.proquest.com/openview/685a87d3d1cea93e7ec9dd50
Web Search
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894487PMC
December 2015

Digital versus screen-film mammography: impact of mammographic density and hormone therapy on breast cancer detection.

Breast Cancer Res Treat 2015 Nov 30;154(2):377-87. Epub 2015 Oct 30.

Women's College Hospital, Sunnybrook Health Sciences Centre, Toronto, Canada.

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http://dx.doi.org/10.1007/s10549-015-3622-xDOI Listing
November 2015

Early detection of chemotherapy-refractory patients by monitoring textural alterations in diffuse optical spectroscopic images.

Med Phys 2015 Nov;42(11):6130-46

Physical Sciences, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario M4N 3M5, Canada; Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5, Canada; and Department of Radiation Oncology, University of Toronto, Toronto, Ontario M4N 3M5, Canada.

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http://dx.doi.org/10.1118/1.4931603DOI Listing
November 2015

Response to: "Counterpoint re: 'Mammography screening-sticking to the science'".

Authors:
Martin J Yaffe

Curr Oncol 2015 Oct;22(5):e400

Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room S657, Toronto, Ontario M4N 3M5,

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http://dx.doi.org/10.3747/co.22.2612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608418PMC
October 2015

Response to: "Beyond the mammography debate: a moderate perspective".

Authors:
Martin J Yaffe

Curr Oncol 2015 Oct;22(5):e401-3

Physical Sciences/Imaging Research, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room S657, Toronto, Ontario M4N 3M5,

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http://dx.doi.org/10.3747/co.22.2578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608419PMC
October 2015

Mean glandular dose coefficients (D(g)N) for x-ray spectra used in contemporary breast imaging systems.

Phys Med Biol 2015 Sep 8;60(18):7179-90. Epub 2015 Sep 8.

Department of Radiology, Biomedical Engineering Graduate Group, University of California Davis, CA 95616, USA.

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http://dx.doi.org/10.1088/0031-9155/60/18/7179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639529PMC
September 2015

Reliability of automated breast density measurements.

Radiology 2015 May 25;275(2):366-76. Epub 2015 Feb 25.

From the Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada (O.A., G.E.M., M.J.Y.); and Department of Public Health Sciences (J.T.P.) and Department of Radiology and Medical Imaging (J.A.H.), University of Virginia, Box 800170, Charlottesville, VA 22908.

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http://dx.doi.org/10.1148/radiol.15141686DOI Listing
May 2015

Tumor shrinkage associated with whole-mount histopathologic techniques in oral tongue carcinoma.

Pathol Res Pract 2015 May 13;211(5):398-403. Epub 2015 Feb 13.

Department of Physical Sciences, Sunnybrook Research Institute, University of Toronto, 2075 Bayview Avenue, Toronto, ON, Canada M4N 3M5. Electronic address:

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http://dx.doi.org/10.1016/j.prp.2015.01.009DOI Listing
May 2015

Evidence that breast tissue stiffness is associated with risk of breast cancer.

PLoS One 2014 10;9(7):e100937. Epub 2014 Jul 10.

Campbell Family Institute for Breast Cancer Research, Ontario Cancer Institute, Toronto, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100937PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091939PMC
March 2015

Quantitative ultrasound spectroscopic imaging for characterization of disease extent in prostate cancer patients.

Transl Oncol 2015 Feb;8(1):25-34

Physical Sciences, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, Canada M4N 3M5; Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada M4N 3M5; Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, ON, Canada M4N 3M5; Department of Radiation Oncology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada M4N 3M5. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2014.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350638PMC
February 2015

Impact of computer-aided detection systems on radiologist accuracy with digital mammography.

AJR Am J Roentgenol 2014 Oct;203(4):909-16

1 Department of Radiology and Radiological Science, Medical University of South Carolina, 96 Jonathan Lucas St, Ste 210, MSC 323, Charleston, SC 29425.

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http://discovery.ucl.ac.uk/1046/1/1046.pdf
Web Search
http://www.ajronline.org/doi/abs/10.2214/AJR.12.10187
Publisher Site
http://dx.doi.org/10.2214/AJR.12.10187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286296PMC
October 2014

Segmenting pectoralis muscle on digital mammograms by a Markov random field-maximum a posteriori model.

J Med Imaging (Bellingham) 2014 Oct 25;1(3):034503. Epub 2014 Nov 25.

Sunnybrook Research Institute , Department of Physical Sciences, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada ; University of Toronto , Department of Medical Biophysics, Toronto, Ontario M5G 1L7, Canada.

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http://dx.doi.org/10.1117/1.JMI.1.3.034503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478980PMC
October 2014

Digital compared to screen-film mammography: breast cancer prognostic features in an organized screening program.

Breast Cancer Res Treat 2014 Sep 10;147(2):389-99. Epub 2014 Aug 10.

Prevention and Cancer Control, Cancer Care Ontario, 620 University Avenue, Toronto, ON, M5G 2L7, Canada,

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http://dx.doi.org/10.1007/s10549-014-3088-2DOI Listing
September 2014

Research in digital mammography and tomosynthesis at the University of Toronto.

Authors:
Martin J Yaffe

Radiol Phys Technol 2014 Jul 25;7(2):191-202. Epub 2014 Jun 25.

Imaging Research Program, Sunnybrook Research Institute, University of Toronto, Toronto, Canada,

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http://dx.doi.org/10.1007/s12194-014-0277-yDOI Listing
July 2014

Early prediction of therapy responses and outcomes in breast cancer patients using quantitative ultrasound spectral texture.

Oncotarget 2014 Jun;5(11):3497-511

Imaging Research - Physical Sciences, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Department of Radiation Oncology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116498PMC
http://dx.doi.org/10.18632/oncotarget.1950DOI Listing
June 2014

Breast cancer screening: should tomosynthesis replace digital mammography?

JAMA 2014 Jun;311(24):2488-9

University of Toronto, Ontario Institute for Cancer Research, Toronto, Canada.

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http://dx.doi.org/10.1001/jama.2014.6421DOI Listing
June 2014

MRI volumetric analysis of breast fibroglandular tissue to assess risk of the spared nipple in BRCA1 and BRCA2 mutation carriers.

Ann Surg Oncol 2014 May 14;21(5):1583-8. Epub 2014 Feb 14.

Division of Plastic and Reconstructive Surgery, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1245/s10434-014-3532-xDOI Listing
May 2014

Digital tomosynthesis: technique.

Radiol Clin North Am 2014 May;52(3):489-97

Sunnybrook Research Insitute, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada.

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http://dx.doi.org/10.1016/j.rcl.2014.01.003DOI Listing
May 2014

Method of measuring NEQ as a quality control metric for digital mammography.

Med Phys 2014 Mar;41(3):031905

Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada and Department of Medical Biophysics, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada.

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http://dx.doi.org/10.1118/1.4865175DOI Listing
March 2014

Overdiagnosing overdiagnosis.

Oncologist 2014 Feb;19(2):103-6

Sunnybrook Research Institute and Sunnybrook Odette Cancer Centre, Toronto, Ontario, Canada; Department of Medical Biophysics and Medical Imaging, University of Toronto, Toronto, Ontario, Canada; Smarter Imaging Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1634/theoncologist.2014-0036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926799PMC
February 2014

Comparative performance of modern digital mammography systems in a large breast screening program.

Med Phys 2013 Dec;40(12):121915

Physical Sciences Division, Sunnybrook Research Institute, Departments of Medical Biophysics and Medical Imaging, University of Toronto, Ontario M4N 3M5, Canada.

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http://dx.doi.org/10.1118/1.4829516DOI Listing
December 2013

Longitudinal changes in IGF-I and IGFBP-3, and mammographic density among postmenopausal women.

Cancer Epidemiol Biomarkers Prev 2013 Nov 9;22(11):2116-20. Epub 2013 Sep 9.

Authors' Affiliations: Obstetrics & Gynaecology and Pediatrics, Dalhousie University, Halifax, Nova Scotia; Faculty of Physical Education and Recreation, University of Alberta; Cross Cancer Institute, Alberta Cancer Board, Edmonton; Alberta Health Services, Calgary, Alberta; Campbell Family Institute for Breast Cancer Research, Ontario Cancer Institute; Sunnybrook Research Institute, Toronto, Ontario; Department of Statistics, University of British Columbia, Vancouver; Southern Medical Program, University of British Columbia (Okanagan Campus), Kelowna, British Columbia, Canada; Fred Hutchison Cancer Research Center, Seattle, Washington; Keck School of Medicine, University of Southern California, Los Angeles, California; and Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico.

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http://dx.doi.org/10.1158/1055-9965.EPI-13-0401DOI Listing
November 2013

Characterization of a constrained paired-view technique in iterative reconstruction for breast tomosynthesis.

Med Phys 2013 Oct;40(10):101901

Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada and Sunnybrook Research Institute, S-657, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5 Canada.

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http://dx.doi.org/10.1118/1.4819943DOI Listing
October 2013

Digital compared with screen-film mammography: performance measures in concurrent cohorts within an organized breast screening program.

Radiology 2013 Sep 14;268(3):684-93. Epub 2013 May 14.

Department of Prevention and Cancer Control, Cancer Care Ontario, 620 University Ave, Toronto, ON, Canada.

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http://dx.doi.org/10.1148/radiol.13122567DOI Listing
September 2013

Diffuse optical imaging for monitoring treatment response in breast cancer patients.

Conf Proc IEEE Eng Med Biol Soc 2012 ;2012:3155-8

Departments of Medical Biophysics and Radiation Oncology, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1109/EMBC.2012.6346634DOI Listing
August 2013

Towards a nanoscale mammographic contrast agent: development of a modular pre-clinical dual optical/x-ray agent.

Phys Med Biol 2013 Aug 12;58(15):5215-35. Epub 2013 Jul 12.

Physical Sciences, Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada.

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http://dx.doi.org/10.1088/0031-9155/58/15/5215DOI Listing
August 2013

Anatomical noise in contrast-enhanced digital mammography. Part II. Dual-energy imaging.

Med Phys 2013 Aug;40(8):081907

Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada.

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http://dx.doi.org/10.1118/1.4812681DOI Listing
August 2013

Density and breast cancer risk.

Radiology 2013 May;267(2):657-8

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http://dx.doi.org/10.1148/radiol.13122477DOI Listing
May 2013

Anatomical noise in contrast-enhanced digital mammography. Part I. Single-energy imaging.

Med Phys 2013 May;40(5):051910

Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada.

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http://dx.doi.org/10.1118/1.4801905DOI Listing
May 2013

Evaluation of neoadjuvant chemotherapy response in women with locally advanced breast cancer using ultrasound elastography.

Transl Oncol 2013 Feb 1;6(1):17-24. Epub 2013 Feb 1.

Department of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada ; Imaging Research - Physical Sciences, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada ; Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada ; Department of Radiation Oncology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573650PMC
http://dx.doi.org/10.1593/tlo.12412DOI Listing
February 2013

The relationship between anatomic noise and volumetric breast density for digital mammography.

Med Phys 2012 Aug;39(8):4660-8

Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada.

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http://dx.doi.org/10.1118/1.4736422DOI Listing
August 2012

Mammographic density and breast cancer risk: current understanding and future prospects.

Breast Cancer Res 2011 1;13(6):223. Epub 2011 Nov 1.

Campbell Family Institute for Breast Cancer Research, Room 10-415, 610 University Avenue, Toronto, ON M5G 2M9, Canada.

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http://breast-cancer-research.biomedcentral.com/articles/10.
Publisher Site
http://dx.doi.org/10.1186/bcr2942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326547PMC
June 2012

Measured and calculated K-fluorescence effects on the MTF of an amorphous-selenium based CCD x-ray detector.

Med Phys 2012 Feb;39(2):608-22

Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1118/1.3673957
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February 2012

Spectral analysis of mammographic images using a multitaper method.

Med Phys 2012 Feb;39(2):801-10

Department of Medical Biophysics, University of Toronto, Ontario, Canada.

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February 2012

Increasing specimen coverage using digital whole-mount breast pathology: implementation, clinical feasibility and application in research.

Comput Med Imaging Graph 2011 Oct-Dec;35(7-8):531-41. Epub 2011 Jun 11.

Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.compmedimag.2011.05.002DOI Listing
January 2012

Mammographic density, response to hormones, and breast cancer risk.

J Clin Oncol 2011 Aug 27;29(22):2985-92. Epub 2011 Jun 27.

DSc, Ontario Cancer Institute, 610 University Ave, Room 10-415, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1200/JCO.2010.33.7964DOI Listing
August 2011

Associations of overall and abdominal adiposity with area and volumetric mammographic measures among postmenopausal women.

Int J Cancer 2011 Jul 16;129(2):440-8. Epub 2010 Nov 16.

Perinatal Epidemiology Research Unit, Departments of Obstetrics & Gynaecology and Pediatrics, Dalhousie University, Nova Scotia, Canada.

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http://doi.wiley.com/10.1002/ijc.25676
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July 2011

Development and evaluation of a robust algorithm for computer-assisted detection of sentinel lymph node micrometastases.

Histopathology 2011 Jul;59(1):116-28

Imaging Research, Sunnybrook Health Sciences Centre, Department of Surgical Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/j.1365-2559.2011.03896.xDOI Listing
July 2011

Tumor characteristics associated with mammographic detection of breast cancer in the Ontario breast screening program.

J Natl Cancer Inst 2011 Jun 3;103(12):942-50. Epub 2011 May 3.

Prevention and Cancer Control, Cancer Care Ontario, 620 University Ave, Toronto, ON M5G 2L7, Canada.

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http://dx.doi.org/10.1093/jnci/djr138DOI Listing
June 2011

Dependence of image quality on geometric factors in breast tomosynthesis.

Med Phys 2011 Jun;38(6):3090-103

Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada.

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http://dx.doi.org/10.1118/1.3591990DOI Listing
June 2011

Improvement in DCIS detection rates by MRI over time in a high-risk breast screening study.

Breast J 2011 Jan-Feb;17(1):9-17

Division of Medical Oncology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/j.1524-4741.2010.01018.xDOI Listing
May 2011

The characterization of breast anatomical metrics using dedicated breast CT.

Med Phys 2011 Apr;38(4):2180-91

Department of Biomedical Engineering, University of California-Davis, One Shields Avenue, Davis, California 95616, USA.

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http://doi.wiley.com/10.1118/1.3567147
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http://dx.doi.org/10.1118/1.3567147DOI Listing
April 2011

Risk of radiation-induced breast cancer from mammographic screening.

Radiology 2011 Jan 16;258(1):98-105. Epub 2010 Nov 16.

Imaging Research Program, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Ave, Room S6-57, Toronto, ON, Canada M4N 3M5.

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http://dx.doi.org/10.1148/radiol.10100655DOI Listing
January 2011

In vitro assessment of poly-iodinated triglyceride reconstituted low-density lipoprotein: initial steps toward CT molecular imaging.

Acad Radiol 2010 Nov 17;17(11):1359-65. Epub 2010 Aug 17.

Imaging Research, Sunnybrook Health Sciences Centre, Room S6-57, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S107663321000311
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http://dx.doi.org/10.1016/j.acra.2010.06.006DOI Listing
November 2010

Cascaded analysis of signal and noise propagation through a heterogeneous breast model.

Med Phys 2010 Oct;37(10):5243-50

Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada.

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http://dx.doi.org/10.1118/1.3483095DOI Listing
October 2010

Breast tissue composition and susceptibility to breast cancer.

J Natl Cancer Inst 2010 Aug 8;102(16):1224-37. Epub 2010 Jul 8.

Campbell Family Institute for Breast Cancer Research, Ontario Cancer Institute, Room 10-415 610 University Ave, Toronto, ON, Canada M5G2M9.

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https://academic.oup.com/jnci/article-lookup/doi/10.1093/jnc
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http://dx.doi.org/10.1093/jnci/djq239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923218PMC
August 2010

Is mammographic breast density a breast cancer risk factor in women with BRCA mutations?

J Clin Oncol 2010 Aug 12;28(23):3779-83. Epub 2010 Jul 12.

Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1200/JCO.2009.27.5933DOI Listing
August 2010

Functional imaging using diffuse optical spectroscopy of neoadjuvant chemotherapy response in women with locally advanced breast cancer.

Clin Cancer Res 2010 May 20;16(9):2605-14. Epub 2010 Apr 20.

Department of Radiation Oncology, Sunnybrook Health Sciences Centre and Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-09-1510DOI Listing
May 2010

Family history, mammographic density, and risk of breast cancer.

Cancer Epidemiol Biomarkers Prev 2010 Feb;19(2):456-63

Campbell Family Institute for Breast Cancer Research, Ontario Cancer Institute, Toronto, Ontario, Canada.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-0
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http://dx.doi.org/10.1158/1055-9965.EPI-09-0881DOI Listing
February 2010