Martin Stanulla

Martin Stanulla

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Martin Stanulla

Martin Stanulla

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Impact of NUDT15 genetics on severe thiopurine-related hematotoxicity in patients with European ancestry.

Genet Med 2019 Feb 7. Epub 2019 Feb 7.

Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.

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http://dx.doi.org/10.1038/s41436-019-0448-7DOI Listing
February 2019

A mathematical model of white blood cell dynamics during maintenance therapy of childhood acute lymphoblastic leukemia.

Math Med Biol 2018 Oct 24. Epub 2018 Oct 24.

Institute of Mathematical Optimization, Faculty of Mathematics, Otto-von-Guericke University Magdeburg, Germany.

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https://academic.oup.com/imammb/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/imammb/dqy017DOI Listing
October 2018

IKZF1 Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia.

J Clin Oncol 2018 Apr 2;36(12):1240-1249. Epub 2018 Mar 2.

Martin Stanulla, Elif Dagdan, Stefanie V. Junk, Laura Hinze, Norman Klein, Christian P. Kratz, Petra Dörge, Doris Steinemann, and Martin Zimmermann, Hannover Medical School; Petra Dörge, German Center for Infection Research, Hannover; Anja Möricke, Kirsten Bleckmann, Denis Schewe, Gunnar Cario, and Martin Schrappe, University Hospital Schleswig-Holstein; Britt-Sabina Petersen and Andre Franke, Kiel University, Kiel; Cornelia Eckert and Stefanie Groeneveld-Krentz, Charité University Hospital; Wolf-Dieter Ludwig, HELIOS-Clinic Berlin-Buch, Berlin; Rolf Koehler, Claus R. Bartram, Andreas Kulozik, and Martina U. Muckenthaler, University of Heidelberg, Heidelberg; Arndt Borkhardt, Heinrich-Heine University, Düsseldorf, Germany; Marketa Zaliova, Charles University and University Hospital Motol, Prague, Czech Republic; Chiara Palmi, Giovanni Cazzaniga, and Andrea Biondi, Azienda Ospedaliera San Gerardo; Maria Grazia Valsecchi, University of Milano-Bicocca, Monza; Geertruy te Kronnie and Giuseppe Basso, University of Padova, Padua, Italy; Jean-Pierre Bourquin and Beat Bornhauser, University Children's Hospital Zurich, Zurich, Switzerland; Shai Izraeli, Sheba Medical Center Tel-Hashomer and Tel Aviv University, Tel Aviv, Israel; Oskar A. Haas and Renate Panzer-Grümayer, St Anna Kinderkrebsforschung and Medical University Vienna, Vienna, Austria; Hélène Cavé, Robert Debré Hospital and Paris-Diderot University, Paris, France; and Richard S. Houlston, The Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2017.74.3617DOI Listing
April 2018

A study on the predictability of acute lymphoblastic leukaemia response to treatment using a hybrid oncosimulator.

Interface Focus 2018 Feb 15;8(1):20160163. Epub 2017 Dec 15.

In Silico Oncology and In Silico Medicine Group, Institute of Communication and Computer Systems, National Technical University of Athens, Athens, Greece.

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http://dx.doi.org/10.1098/rsfs.2016.0163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740218PMC
February 2018

Five percent of healthy newborns have an fusion as revealed by DNA-based GIPFEL screening.

Blood 2018 02 8;131(7):821-826. Epub 2018 Jan 8.

Department of Pediatric Oncology, Hematology, and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.

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http://dx.doi.org/10.1182/blood-2017-09-808402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909885PMC
February 2018

NGS-based methylation profiling differentiates TCF3-HLF and TCF3-PBX1 positive B-cell acute lymphoblastic leukemia.

Epigenomics 2018 02 15;10(2):133-147. Epub 2018 Jan 15.

Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel 24105, Germany.

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http://dx.doi.org/10.2217/epi-2017-0080DOI Listing
February 2018

Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology.

Am J Med Genet A 2017 Apr 7;173(4):1017-1037. Epub 2017 Feb 7.

Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1002/ajmg.a.38142DOI Listing
April 2017

T-cell acute lymphoblastic leukemia in infants has distinct genetic and epigenetic features compared to childhood cases.

Genes Chromosomes Cancer 2017 02 26;56(2):159-167. Epub 2016 Oct 26.

Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine-University, Medical Faculty, Düsseldorf, Germany.

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http://dx.doi.org/10.1002/gcc.22423DOI Listing
February 2017

Genetic predisposition to acute lymphoblastic leukemia: Overview on behalf of the I-BFM ALL Host Genetic Variation Working Group.

Eur J Med Genet 2016 Mar 15;59(3):111-5. Epub 2015 Dec 15.

Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Robert Debré, Département de Génétique, Paris, France; INSERM UMR 1131, Institut Universitaire d'Hématologie, Université Paris Diderot, Paris-Sorbonne-Cité, Paris, France.

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http://dx.doi.org/10.1016/j.ejmg.2015.10.003DOI Listing
March 2016

Evaluation of a pediatric liquid formulation to improve 6-mercaptopurine therapy in children.

Eur J Pharm Sci 2016 Feb 2;83:1-7. Epub 2015 Dec 2.

Department of Pediatric Pharmacology and Pharmacogenetics and Clinical Investigations Center CIC1426 INSERM, Robert Debre Hospital, Assistance Publique Hopitaux de Paris, Paris, France; University Paris VII Diderot, Paris, France.

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http://adc.bmj.com/content/101/1/e1.60.full.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S092809871530076
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http://dx.doi.org/10.1016/j.ejps.2015.12.002DOI Listing
February 2016

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.

Nat Genet 2015 Sep 27;47(9):1020-1029. Epub 2015 Jul 27.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany.

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http://dx.doi.org/10.1038/ng.3362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603357PMC
September 2015

Vy-PER: eliminating false positive detection of virus integration events in next generation sequencing data.

Sci Rep 2015 Jul 13;5:11534. Epub 2015 Jul 13.

Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Schleswig-Holstein, D-24105 Kiel, Germany.

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http://dx.doi.org/10.1038/srep11534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499804PMC
July 2015

Childhood cancer incidence patterns by race, sex and age for 2000-2006: a report from the South African National Cancer Registry.

Int J Cancer 2015 Jun 21;136(11):2628-39. Epub 2014 Nov 21.

Section of Environment and Radiation, International Agency for Research on Cancer (IARC), 150 Cours Albert Thomas, 69372, Lyon, France.

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http://dx.doi.org/10.1002/ijc.29308DOI Listing
June 2015

Central nervous system acute lymphoblastic leukemia: role of natural killer cells.

Blood 2015 May 20;125(22):3420-31. Epub 2015 Apr 20.

Childhood Leukemia Research Section, Department of Pediatric Oncology and the Cancer Research Center, Edmond and Lily Safra Children Hospital and Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel; Department of Human Molecular Genetics and Biochemistry, Tel Aviv University, Tel Aviv, Israel;

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http://dx.doi.org/10.1182/blood-2014-08-595108DOI Listing
May 2015

IKZF1 status as a prognostic feature in BCR-ABL1-positive childhood ALL.

Blood 2014 Mar 23;123(11):1691-8. Epub 2013 Dec 23.

Department of Pediatric Oncology, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands;

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http://dx.doi.org/10.1182/blood-2013-06-509794DOI Listing
March 2014

Germline genetic variations in methotrexate candidate genes are associated with pharmacokinetics, toxicity, and outcome in childhood acute lymphoblastic leukemia.

Blood 2013 Jun 7;121(26):5145-53. Epub 2013 May 7.

Department for Pediatric Oncology and Immunology, Late Effects Surveillance System Center, University Hospital for Children and Adolescents, Erlangen, Germany.

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http://dx.doi.org/10.1182/blood-2013-01-480335DOI Listing
June 2013

Ikaros (IKZF1) alterations and minimal residual disease at day 15 assessed by flow cytometry predict prognosis of childhood BCR/ABL-negative acute lymphoblastic leukemia.

Pediatr Blood Cancer 2013 Mar 19;60(3):420-7. Epub 2012 Sep 19.

2nd Faculty of Medicine, Department of Pediatric Hematology and Oncology, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/pbc.24299DOI Listing
March 2013

[Treatment of acute lymphoblastic leukemia in childhood: state of things and outlook for the future].

Pharm Unserer Zeit 2012 May;41(3):203-13

Kinderklinik am Universitätsklinikum, Schleswig-Holstein, Campus Kiel, Kiel.

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May 2012

NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway.

Nat Med 2009 Feb 1;15(2):151-8. Epub 2009 Feb 1.

Department of Molecular Hematopoiesis, Hannover Medical School, Carl-Neuberg Strasse 1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1038/nm.1913DOI Listing
February 2009

Treatment of childhood acute lymphoblastic leukemia.

Semin Hematol 2009 Jan;46(1):52-63

Department of Pediatrics, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1053/j.seminhematol.2008.09.007DOI Listing
January 2009

Anemia and survival in childhood acute lymphoblastic leukemia.

Haematologica 2008 Nov 24;93(11):1652-7. Epub 2008 Sep 24.

University Children's Hospital Zurich, Steinwiesstrasse 75 Zurich, 8032 Switzerland.

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http://dx.doi.org/10.3324/haematol.13156DOI Listing
November 2008

Initial leukemic gene expression profiles of patients with poor in vivo prednisone response are similar to those of blasts persisting under prednisone treatment in childhood acute lymphoblastic leukemia.

Ann Hematol 2008 Sep 3;87(9):709-16. Epub 2008 Jun 3.

Department of Pediatrics, University Hospital Schleswig-Holstein, Campus Kiel, Schwanenweg 20, 24105 Kiel, Germany.

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http://dx.doi.org/10.1007/s00277-008-0504-xDOI Listing
September 2008

Misconceptions, challenges, uncertainty, and progress in guideline recommendations.

Semin Hematol 2008 Jul;45(3):167-75

Basel Institute of Clinical Epidemiology, University Hospital Basel, Basel, Switzerland.

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http://dx.doi.org/10.1053/j.seminhematol.2008.04.005DOI Listing
July 2008

Integrating molecular information into treatment of childhood acute lymphoblastic leukemia--a perspective from the BFM Study Group.

Blood Cells Mol Dis 2007 Sep-Oct;39(2):160-3. Epub 2007 May 25.

Department of Pediatric Hematology and Oncology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1016/j.bcmd.2007.04.005DOI Listing
September 2007