Mark Wade

Mark Wade

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Mark Wade

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Telomere Length and Psychopathology: Specificity and Direction of Effects Within the Bucharest Early Intervention Project.

J Am Acad Child Adolesc Psychiatry 2020 Jan 4;59(1):140-148.e3. Epub 2019 Mar 4.

Tulane University School of Medicine, New Orleans, LA.

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http://dx.doi.org/10.1016/j.jaac.2019.02.013DOI Listing
January 2020

Adverse Childhood Experiences: Implications for Offspring Telomere Length and Psychopathology.

Am J Psychiatry 2020 Jan 6;177(1):47-57. Epub 2019 Sep 6.

The Department of Psychiatry and Behavioral Sciences, Tulane University School of Medicine, New Orleans (Esteves, Drury); the Department of Neuroscience, Tulane Brain Institute, Tulane University, New Orleans (Jones, Drury); the Department of Applied Psychology and Human Development, University of Toronto (Wade); the Department of Cell and Molecular Biology, Tulane University, New Orleans (Callerame); the Department of Obstetrics and Gynecology, Emory University, Atlanta (Smith); and the Department of Global Community Health and Behavioral Sciences, Tulane University School of Public Health and Tropical Medicine, Tulane University, New Orleans (Theall).

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http://dx.doi.org/10.1176/appi.ajp.2019.18030335DOI Listing
January 2020

Cognitive sensitivity and child receptive vocabulary: A between- and within-family study of mothers and sibling pairs.

Dev Psychol 2019 Oct 8;55(10):2123-2134. Epub 2019 Jul 8.

Department of Applied Psychology and Human Development, University of Toronto.

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http://dx.doi.org/10.1037/dev0000775DOI Listing
October 2019

The link between maternal and child verbal abilities: An indirect effect through maternal responsiveness.

Dev Sci 2019 Sep 30:e12907. Epub 2019 Sep 30.

Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1111/desc.12907DOI Listing
September 2019

The Histone Demethylase Enzymes KDM3A and KDM4B Co-Operatively Regulate Chromatin Transactions of the Estrogen Receptor in Breast Cancer.

Cancers (Basel) 2019 Aug 6;11(8). Epub 2019 Aug 6.

Biomedical Sciences, Faculty of Health Sciences, University of Hull, Hull HU6 7RX, UK.

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http://dx.doi.org/10.3390/cancers11081122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721541PMC
August 2019

Global deficits in executive functioning are transdiagnostic mediators between severe childhood neglect and psychopathology in adolescence.

Psychol Med 2019 Aug 8:1-8. Epub 2019 Aug 8.

Harvard Graduate School of Education,Cambridge, MA,USA.

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http://dx.doi.org/10.1017/S0033291719001764DOI Listing
August 2019

Neck lump clinic: a new initiative at North Shore Hospital.

ANZ J Surg 2019 07 15;89(7-8):853-857. Epub 2019 Apr 15.

Otorhinolaryngology, Waitemata District Health Board, Auckland, New Zealand.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ans.15120
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http://dx.doi.org/10.1111/ans.15120DOI Listing
July 2019

Omitted Acknowledgment of Local Contributors to Study.

Authors:
Mark Wade

JAMA Psychiatry 2019 04;76(4):447

Division of Developmental Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamapsychiatry.2018.4596DOI Listing
April 2019

Long-term effects of institutional rearing, foster care, and brain activity on memory and executive functioning.

Proc Natl Acad Sci U S A 2019 01 14;116(5):1808-1813. Epub 2019 Jan 14.

Laboratories of Cognitive Neuroscience, Boston Children's Hospital and Harvard Medical School, Boston, MA 02215.

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http://www.pnas.org/lookup/doi/10.1073/pnas.1809145116
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http://dx.doi.org/10.1073/pnas.1809145116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358707PMC
January 2019

On the relation between theory of mind and executive functioning: A developmental cognitive neuroscience perspective.

Psychon Bull Rev 2018 Dec;25(6):2119-2140

Dr Eric Jackman Institute of Child Study, University of Toronto, Toronto, Ontario, Canada.

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http://link.springer.com/10.3758/s13423-018-1459-0
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http://dx.doi.org/10.3758/s13423-018-1459-0DOI Listing
December 2018

Child and contextual effects in the emergence of differential maternal sensitivity across siblings.

Dev Psychol 2018 Jul 16;54(7):1265-1276. Epub 2018 Apr 16.

Department of Applied Psychology and Human Development, University of Toronto.

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http://dx.doi.org/10.1037/dev0000506DOI Listing
July 2018

Cumulative psychosocial risk, parental socialization, and child cognitive functioning: A longitudinal cascade model.

Dev Psychol 2018 06 21;54(6):1038-1050. Epub 2017 Dec 21.

Department of Applied Psychology and Human Development, University of Toronto.

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http://dx.doi.org/10.1037/dev0000493DOI Listing
June 2018

Latent Profiles of Externalizing Psychopathology and Their Relation to Children's Aggression and Social Behavior.

J Dev Behav Pediatr 2016 Jul-Aug;37(6):442-50

*Centre for Addiction and Mental Health, Toronto, ON, Canada; †Department of Psychiatry, University of Toronto, Toronto, ON, Canada; ‡Department of Applied Psychology and Human Development, Ontario Institute for Studies in Education, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/DBP.0000000000000304DOI Listing
December 2017

Visualization of Protein Interactions in Living Cells Using Bimolecular Luminescence Complementation (BiLC).

Curr Protoc Protein Sci 2017 11 1;90:30.5.1-30.5.14. Epub 2017 Nov 1.

Center for Genomic Science of IIT@SEMM, Fondazione Istituto Italiano di Tecnologia, Milan, Italy.

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http://dx.doi.org/10.1002/cpps.42DOI Listing
November 2017

Maternal Adverse Childhood Experience and Infant Health: Biomedical and Psychosocial Risks as Intermediary Mechanisms.

J Pediatr 2017 08 23;187:282-289.e1. Epub 2017 May 23.

Department of Applied Psychology and Human Development, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2017.04.052DOI Listing
August 2017

Trajectories of maternal depressive symptoms in the early childhood period and family-wide clustering of risk.

J Affect Disord 2017 06 7;215:49-55. Epub 2017 Mar 7.

Department of Applied Psychology and Human Development, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2017.03.016DOI Listing
June 2017

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.

Mol Cell 2017 Apr 23;66(1):22-37.e9. Epub 2017 Mar 23.

Department of Biology and Biotechnology Charles Darwin and IBPM, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, Italy; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy; Institut Pasteur Italy, Fondazione Cenci-Bolognetti, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.02.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387670PMC
April 2017

Oxytocin and vasopressin hormone genes in children's externalizing problems: A cognitive endophenotype approach.

Horm Behav 2016 06 4;82:78-86. Epub 2016 May 4.

Department of Applied Psychology and Human Development, University of Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.yhbeh.2016.05.002DOI Listing
June 2016

Neighborhood Collective Efficacy Moderates the Association between Maternal Adverse Childhood Experiences and Marital Conflict.

Am J Community Psychol 2016 06 2;57(3-4):437-47. Epub 2016 Jun 2.

Applied Psychology and Human Development, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1002/ajcp.12053DOI Listing
June 2016

Does radiation-induced c-MYC amplification initiate breast oncogenesis?

Mol Cell Oncol 2016 Jan-Feb;3(1):e1010950. Epub 2015 Feb 3.

Northern Institute for Cancer Research; Newcastle University ; Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1080/23723556.2015.1010950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845163PMC
June 2016

Using Sibling Designs to Understand Neurodevelopmental Disorders: From Genes and Environments to Prevention Programming.

Biomed Res Int 2015 15;2015:672784. Epub 2015 Jul 15.

Department of Psychology, University of Calgary, 2500 University Drive NW, Calgary, AB, Canada T2N 1N4.

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http://dx.doi.org/10.1155/2015/672784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518166PMC
May 2016

Cumulative risk and developmental health: an argument for the importance of a family-wide science.

Wiley Interdiscip Rev Cogn Sci 2015 Jul-Aug;6(4):397-407. Epub 2015 Apr 8.

Applied Psychology and Human Development, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/wcs.1349DOI Listing
May 2016

Pregnancy hypertension and the risk for neuropsychological difficulties across early development: A brief report.

Child Neuropsychol 2016 16;22(2):247-54. Epub 2014 Oct 16.

a Department of Applied Psychology and Human Development , University of Toronto , Toronto , ON , Canada.

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http://dx.doi.org/10.1080/09297049.2014.958070DOI Listing
March 2016

Cumulative risk disparities in children's neurocognitive functioning: a developmental cascade model.

Dev Sci 2016 Mar 6;19(2):179-94. Epub 2015 Apr 6.

Department of Applied Psychology and Human Development, University of Toronto, Canada.

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http://dx.doi.org/10.1111/desc.12302DOI Listing
March 2016

Inhibition of MARCH5 ubiquitin ligase abrogates MCL1-dependent resistance to BH3 mimetics via NOXA.

Oncotarget 2016 Mar;7(13):15986-6002

Center for Genomic Science of IIT@SEMM, Fondazione Istituto Italiano di Tecnologia, Milano, Italy.

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http://dx.doi.org/10.18632/oncotarget.7558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941292PMC
March 2016

Genome and network visualization facilitates the analyses of the effects of drugs and mutations on protein-protein and drug-protein networks.

BMC Bioinformatics 2016 Mar 2;17 Suppl 4:54. Epub 2016 Mar 2.

Center for Genomic Science of IIT@SEMM, Fondazione Istituto Italiano di Tecnologia (IIT), Via Adamello 16, Milan, I-20139, Italy.

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http://dx.doi.org/10.1186/s12859-016-0908-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896239PMC
March 2016

Multiplex detection of protein-protein interactions using a next generation luciferase reporter.

Biochim Biophys Acta 2016 Feb 28;1863(2):284-92. Epub 2015 Nov 28.

Center for Genomic Science of IIT@SEMM, Fondazione Istituto Italiano di Tecnologia, Via Adamello 16, 20139 Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2015.11.031DOI Listing
February 2016

Gene-environment interaction between the oxytocin receptor (OXTR) gene and parenting behaviour on children's theory of mind.

Soc Cogn Affect Neurosci 2015 Dec 14;10(12):1749-57. Epub 2015 May 14.

Department of Applied Psychology and Human Development, University of Toronto, 252 Bloor Street West, Toronto, Ontario, Canada M5S 1V6 and

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http://dx.doi.org/10.1093/scan/nsv064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666114PMC
December 2015

A pilot study of JI-101, an inhibitor of VEGFR-2, PDGFR-β, and EphB4 receptors, in combination with everolimus and as a single agent in an ovarian cancer expansion cohort.

Invest New Drugs 2015 Dec 14;33(6):1217-24. Epub 2015 Sep 14.

Department of Medicine, Oncology Division, University of Utah, Huntsman Cancer Institute, Salt Lake City, UT, USA.

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http://dx.doi.org/10.1007/s10637-015-0288-5DOI Listing
December 2015

Improving eye safety in citrus harvest crews through the acceptance of personal protective equipment, community-based participatory research, social marketing, and community health workers.

J Agromedicine 2014 ;19(2):107-16

a J. Antonio Tovar-Aguilar, Carol A. Bryant, and Robert J. McDermott are affiliated with the Florida Prevention Research Center , University of South Florida College of Public Health , Tampa , Florida , USA .

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http://dx.doi.org/10.1080/1059924X.2014.884397DOI Listing
November 2015

Maternal abuse history, postpartum depression, and parenting: links with preschoolers' internalizing problems.

Infant Ment Health J 2015 Mar-Apr;36(2):146-55. Epub 2015 Jan 12.

University of Toronto and Hospital for Sick Children.

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http://dx.doi.org/10.1002/imhj.21496DOI Listing
November 2015

Birth Weight Variability and Language Development: Risk, Resilience, and Responsive Parenting.

J Pediatr Psychol 2015 Oct 24;40(9):869-77. Epub 2015 Jun 24.

University of Toronto and.

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http://dx.doi.org/10.1093/jpepsy/jsv056DOI Listing
October 2015

Circadian clock: Time for novel anticancer strategies?

Pharmacol Res 2015 Oct 28;100:288-95. Epub 2015 Aug 28.

Department of Drug Discovery and Development, Fondazione Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10436618150017
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http://dx.doi.org/10.1016/j.phrs.2015.08.008DOI Listing
October 2015

FOXA1 regulates androgen receptor variant activity in models of castrate-resistant prostate cancer.

Oncotarget 2015 Oct;6(30):29782-94

Northern Institute for Cancer Research, Newcastle University, Newcastle Upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.18632/oncotarget.4927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745762PMC
October 2015

High-Throughput Silencing Using the CRISPR-Cas9 System: A Review of the Benefits and Challenges.

Authors:
Mark Wade

J Biomol Screen 2015 Sep 22;20(8):1027-39. Epub 2015 May 22.

Screening Unit, Center for Genomic Science of IIT@SEMM, Istituto Italiano di Tecnologia, Milan, Italy

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http://dx.doi.org/10.1177/1087057115587916DOI Listing
September 2015

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

Authors:
William H Goodson Leroy Lowe David O Carpenter Michael Gilbertson Abdul Manaf Ali Adela Lopez de Cerain Salsamendi Ahmed Lasfar Amancio Carnero Amaya Azqueta Amedeo Amedei Amelia K Charles Andrew R Collins Andrew Ward Anna C Salzberg Annamaria Colacci Ann-Karin Olsen Arthur Berg Barry J Barclay Binhua P Zhou Carmen Blanco-Aparicio Carolyn J Baglole Chenfang Dong Chiara Mondello Chia-Wen Hsu Christian C Naus Clement Yedjou Colleen S Curran Dale W Laird Daniel C Koch Danielle J Carlin Dean W Felsher Debasish Roy Dustin G Brown Edward Ratovitski Elizabeth P Ryan Emanuela Corsini Emilio Rojas Eun-Yi Moon Ezio Laconi Fabio Marongiu Fahd Al-Mulla Ferdinando Chiaradonna Firouz Darroudi Francis L Martin Frederik J Van Schooten Gary S Goldberg Gerard Wagemaker Gladys N Nangami Gloria M Calaf Graeme Williams Gregory T Wolf Gudrun Koppen Gunnar Brunborg H Kim Lyerly Harini Krishnan Hasiah Ab Hamid Hemad Yasaei Hideko Sone Hiroshi Kondoh Hosni K Salem Hsue-Yin Hsu Hyun Ho Park Igor Koturbash Isabelle R Miousse A Ivana Scovassi James E Klaunig Jan Vondráček Jayadev Raju Jesse Roman John Pierce Wise Jonathan R Whitfield Jordan Woodrick Joseph A Christopher Josiah Ochieng Juan Fernando Martinez-Leal Judith Weisz Julia Kravchenko Jun Sun Kalan R Prudhomme Kannan Badri Narayanan Karine A Cohen-Solal Kim Moorwood Laetitia Gonzalez Laura Soucek Le Jian Leandro S D'Abronzo Liang-Tzung Lin Lin Li Linda Gulliver Lisa J McCawley Lorenzo Memeo Louis Vermeulen Luc Leyns Luoping Zhang Mahara Valverde Mahin Khatami Maria Fiammetta Romano Marion Chapellier Marc A Williams Mark Wade Masoud H Manjili Matilde E Lleonart Menghang Xia Michael J Gonzalez Michalis V Karamouzis Micheline Kirsch-Volders Monica Vaccari Nancy B Kuemmerle Neetu Singh Nichola Cruickshanks Nicole Kleinstreuer Nik van Larebeke Nuzhat Ahmed Olugbemiga Ogunkua P K Krishnakumar Pankaj Vadgama Paola A Marignani Paramita M Ghosh Patricia Ostrosky-Wegman Patricia A Thompson Paul Dent Petr Heneberg Philippa Darbre Po Sing Leung Pratima Nangia-Makker Qiang Shawn Cheng R Brooks Robey Rabeah Al-Temaimi Rabindra Roy Rafaela Andrade-Vieira Ranjeet K Sinha Rekha Mehta Renza Vento Riccardo Di Fiore Richard Ponce-Cusi Rita Dornetshuber-Fleiss Rita Nahta Robert C Castellino Roberta Palorini Roslida Abd Hamid Sabine A S Langie Sakina E Eltom Samira A Brooks Sandra Ryeom Sandra S Wise Sarah N Bay Shelley A Harris Silvana Papagerakis Simona Romano Sofia Pavanello Staffan Eriksson Stefano Forte Stephanie C Casey Sudjit Luanpitpong Tae-Jin Lee Takemi Otsuki Tao Chen Thierry Massfelder Thomas Sanderson Tiziana Guarnieri Tove Hultman Valérian Dormoy Valerie Odero-Marah Venkata Sabbisetti Veronique Maguer-Satta W Kimryn Rathmell Wilhelm Engström William K Decker William H Bisson Yon Rojanasakul Yunus Luqmani Zhenbang Chen Zhiwei Hu

Carcinogenesis 2015 Jun;36 Suppl 1:S254-96

Department of Surgery, The Ohio State University College of Medicine, The James Comprehensive Cancer Center, Columbus, OH 43210, USA.

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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://www.ilcambiamento.it/files/carcinogenesi.pdf
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http://www.carcin.oxfordjournals.org/lookup/doi/10.1093/carc
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http://dx.doi.org/10.1093/carcin/bgv039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480130PMC
June 2015

The development of a measure of maternal cognitive sensitivity appropriate for use in primary care health settings.

J Child Psychol Psychiatry 2015 Apr 3;56(4):488-95. Epub 2014 Sep 3.

Ontario Institute for Studies in Education, University of Toronto, Applied Psychology and Human Development, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/jcpp.12322DOI Listing
April 2015

Cumulative biomedical risk and social cognition in the second year of life: prediction and moderation by responsive parenting.

Front Psychol 2015 1;6:354. Epub 2015 Apr 1.

Department of Applied Psychology and Human Development, University of Toronto Toronto, ON, Canada.

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http://dx.doi.org/10.3389/fpsyg.2015.00354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381485PMC
April 2015

Open access to high-content clonogenic analysis.

J Biomol Screen 2015 Mar 7;20(3):391-401. Epub 2014 Nov 7.

Center for Genomic Science of IIT@SEMM, Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy.

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http://dx.doi.org/10.1177/1087057114557775DOI Listing
March 2015

Cumulative contextual risk, maternal responsivity, and social cognition at 18 months.

Dev Psychopathol 2015 Feb 14;27(1):189-203. Epub 2014 Jul 14.

University of Toronto.

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http://dx.doi.org/10.1017/S0954579414000674DOI Listing
February 2015

The histone demethylase enzyme KDM3A is a key estrogen receptor regulator in breast cancer.

Nucleic Acids Res 2015 Jan 8;43(1):196-207. Epub 2014 Dec 8.

Northen Institute for Cancer Research, Newcastle University, Newcastle upon Tyne NE2 4HH, UK

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http://academic.oup.com/nar/article/43/1/196/1007966/The-his
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http://dx.doi.org/10.1093/nar/gku1298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288188PMC
January 2015

Medical nonadherence in pediatric HIV: psychosocial risks and intersection with the child protection system for medical neglect.

Child Abuse Negl 2014 Nov 26;38(11):1766-77. Epub 2014 Sep 26.

The Hospital for Sick Children, Division of Infectious Diseases, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8; University of Toronto, Faculty of Medicine, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.chiabu.2014.08.013DOI Listing
November 2014

Association between the arginine vasopressin receptor 1A (AVPR1A) gene and preschoolers' executive functioning.

Brain Cogn 2014 Oct 11;90:116-23. Epub 2014 Jul 11.

Department of Applied Psychology and Human Development, University of Toronto, 252 Bloor Street West, Toronto, Ontario M5S 1V6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bandc.2014.06.002DOI Listing
October 2014

Association between abuse history and adolescent pregnancy: a meta-analysis.

J Adolesc Health 2014 Aug;55(2):151-9

Suspected Child Abuse and Neglect Program, The Hospital for Sick Children, Toronto, Ontario, Canada; Applied Psychology and Human Development, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jadohealth.2014.05.002DOI Listing
August 2014

KDM4B is a master regulator of the estrogen receptor signalling cascade.

Nucleic Acids Res 2013 Aug 30;41(14):6892-904. Epub 2013 May 30.

Solid Tumour Target Discovery Group, Northern Institute for Cancer Research, Newcastle University, Paul O'Gorman Building, Newcastle Upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.1093/nar/gkt469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737554PMC
August 2013

Depletion-mode carrier-plasma optical modulator in zero-change advanced CMOS.

Opt Lett 2013 Aug;38(15):2657-9

Department of Electrical, Computer and Energy Engineering, University of Colorado, Boulder, Colorado 80309, USA.

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http://plab.colorado.edu/pubs_pdfs/j26.pdf
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http://dx.doi.org/10.1364/OL.38.002657DOI Listing
August 2013

Depletion-mode polysilicon optical modulators in a bulk complementary metal-oxide semiconductor process.

Opt Lett 2013 Aug;38(15):2729-31

Department of Electrical, Computer and Energy Engineering, University of Colorado, Boulder, Colorado 80309, USA.

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http://dx.doi.org/10.1364/OL.38.002729DOI Listing
August 2013

Efficient wavelength multiplexers based on asymmetric response filters.

Opt Express 2013 May;21(9):10903-16

Department of Electrical, Computer, and Energy Engineering, University of Colorado, Boulder, Colorado 80309, USA.

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http://dx.doi.org/10.1364/OE.21.010903DOI Listing
May 2013

MDM2, MDMX and p53 in oncogenesis and cancer therapy.

Nat Rev Cancer 2013 Feb 10;13(2):83-96. Epub 2013 Jan 10.

Center for Genomic Science of IIT@SEMM, Fondazione Istituto Italiano di Tecnologia, Via Adamello 16, 20139 Milan, Italy.

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http://dx.doi.org/10.1038/nrc3430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161369PMC
February 2013

Modulation of neurotransmitter release in orexin/hypocretin-2 receptor knockout mice: a microdialysis study.

J Neurosci Res 2012 Mar 31;90(3):588-96. Epub 2011 Oct 31.

Eli Lilly and Co., Indianapolis, Indiana 46240-0510, USA.

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http://doi.wiley.com/10.1002/jnr.22781
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http://dx.doi.org/10.1002/jnr.22781DOI Listing
March 2012

Design, Synthesis and Biological Evaluation of a Series of Novel Axl Kinase Inhibitors.

ACS Med Chem Lett 2011 Dec;2(12):907-912

Center for Investigational Therapeutics, Huntsman Cancer Institute, 2000 Circle of Hope, Salt Lake City, UT 84112, United States.

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http://dx.doi.org/10.1021/ml200198xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254106PMC
December 2011

A stapled p53 helix overcomes HDMX-mediated suppression of p53.

Cancer Cell 2010 Nov;18(5):411-22

Department of Pediatric Oncology, Dana-Farber Cancer Institute and Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S153561081000426
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http://dx.doi.org/10.1016/j.ccr.2010.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050021PMC
November 2010

The p53 orchestra: Mdm2 and Mdmx set the tone.

Trends Cell Biol 2010 May 19;20(5):299-309. Epub 2010 Feb 19.

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S096289241000033
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http://dx.doi.org/10.1016/j.tcb.2010.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910097PMC
May 2010

Fiberoptic resonance Raman spectroscopy to measure carotenoid oxidative breakdown in live tissues.

Cancer Prev Res (Phila) 2010 Apr 30;3(4):529-38. Epub 2010 Mar 30.

Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Utah School of Medicine, 50 North Medical Drive, Salt Lake City, UT 84132, USA.

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April 2010

CB1 receptor knockout mice are hyporesponsive to the behavior-stimulating actions of d-amphetamine: role of mGlu5 receptors.

Eur Neuropsychopharmacol 2009 Mar 29;19(3):196-204. Epub 2008 Dec 29.

Eli Lilly & Company, Lilly Corporate Center, Neuroscience Discovery Research, Indianapolis, IN 46285-0510, USA.

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http://dx.doi.org/10.1016/j.euroneuro.2008.11.003DOI Listing
March 2009

Targeting Mdm2 and Mdmx in cancer therapy: better living through medicinal chemistry?

Mol Cancer Res 2009 Jan;7(1):1-11

Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://mcr.aacrjournals.org/lookup/doi/10.1158/1541-7786.MCR
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http://dx.doi.org/10.1158/1541-7786.MCR-08-0423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629357PMC
January 2009

Role of metabotropic glutamate receptor 5 in the procholinergic effects of neuropsychotherapeutic compounds.

Synapse 2008 Dec;62(12):940-3

Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, USA.

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http://dx.doi.org/10.1002/syn.20560DOI Listing
December 2008

Acetylcholine release by human colon cancer cells mediates autocrine stimulation of cell proliferation.

Am J Physiol Gastrointest Liver Physiol 2008 Sep 24;295(3):G591-7. Epub 2008 Jul 24.

Division of Gastroenterology and Hepatology, Veterans Affairs Maryland Healthcare System, University of Maryland School of Medicine, Department of Pathology, 22 S. Greene St., N3W62, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1152/ajpgi.00055.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2536781PMC
September 2008

BH3 activation blocks Hdmx suppression of apoptosis and cooperates with Nutlin to induce cell death.

Cell Cycle 2008 Jul;7(13):1973-82

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA.

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http://dx.doi.org/10.4161/cc.7.13.6072DOI Listing
July 2008

The vesicular glutamate transporter VGLUT3 synergizes striatal acetylcholine tone.

Nat Neurosci 2008 Mar 17;11(3):292-300. Epub 2008 Feb 17.

Institut National de la Santé et de la Recherche Médicale, U513, Université Pierre et Marie Curie, 9 quai Saint Bernard, 75005 Paris, France.

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http://dx.doi.org/10.1038/nn2052DOI Listing
March 2008

Ecological restoration of farmland: progress and prospects.

Philos Trans R Soc Lond B Biol Sci 2008 Feb;363(1492):831-47

National Centre for Advanced Bio-Protection Technologies, PO Box 84, Lincoln University, Canterbury, New Zealand.

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http://dx.doi.org/10.1098/rstb.2007.2186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2610112PMC
February 2008

Behavioral and biochemical responses to d-amphetamine in MCH1 receptor knockout mice.

Synapse 2008 Feb;62(2):128-36

Eli Lilly and Company, Neuroscience Discovery Research, Indianapolis, Indiana 46285, USA.

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http://dx.doi.org/10.1002/syn.20473DOI Listing
February 2008

Quantitative analyses reveal the importance of regulated Hdmx degradation for p53 activation.

Proc Natl Acad Sci U S A 2007 Jul 17;104(30):12365-70. Epub 2007 Jul 17.

Gene Expression Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1941475PMC
July 2007

Epstein-barr virus-induced resistance to drugs that activate the mitotic spindle assembly checkpoint in Burkitt's lymphoma cells.

J Virol 2007 Jan 11;81(1):248-60. Epub 2006 Oct 11.

Department of Virology, Faculty of Medicine, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom.

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http://dx.doi.org/10.1128/JVI.01096-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797259PMC
January 2007

Cannabinoid CB1 receptor antagonism modulates plasma corticosterone in rodents.

Eur J Pharmacol 2006 Dec 12;551(1-3):162-7. Epub 2006 Sep 12.

Eli Lilly and Company, Lilly Research Laboratories, Neuroscience Discovery Research, Indianapolis, IN 46285-0510, USA.

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December 2006

Hdmx modulates the outcome of p53 activation in human tumor cells.

J Biol Chem 2006 Nov 13;281(44):33036-44. Epub 2006 Aug 13.

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA.

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November 2006