Publications by authors named "Mark T Quinn"

100Publications

Alarmins and c-Jun N-Terminal Kinase (JNK) Signaling in Neuroinflammation.

Cells 2020 10 24;9(11). Epub 2020 Oct 24.

Kizhner Research Center, Tomsk Polytechnic University, 634050 Tomsk, Russia.

View Article and Find Full Text PDF
October 2020

Essential Oils from : Chemical Composition and Activation of Transient Receptor Potential A1 (TRPA1) Channels.

Molecules 2020 Oct 22;25(21). Epub 2020 Oct 22.

Department of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, USA.

View Article and Find Full Text PDF
October 2020

Novel Sulfonamide Analogs of Sivelestat as Potent Human Neutrophil Elastase Inhibitors.

Front Chem 2020 1;8:795. Epub 2020 Sep 1.

Department of Microbiology and Immunology, Montana State University, Bozeman, MT, United States.

View Article and Find Full Text PDF
September 2020

Therapeutic Effects of Tryptanthrin and Tryptanthrin-6-Oxime in Models of Rheumatoid Arthritis.

Front Pharmacol 2020 24;11:1145. Epub 2020 Jul 24.

Department of Microbiology and Immunology, Montana State University, Bozeman, MT, United States.

View Article and Find Full Text PDF
July 2020

Chemical Composition and Immunomodulatory Activity of Essential Oils.

Biomolecules 2020 06 17;10(6). Epub 2020 Jun 17.

Department of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, USA.

View Article and Find Full Text PDF
June 2020

Aurantiamide-related dipeptide derivatives are formyl peptide receptor 1 antagonists.

Medchemcomm 2019 Dec 7;10(12):2078-2088. Epub 2019 Oct 7.

Dipartimento di Farmacia - Scienze del Farmaco , Università degli Studi di Bari Aldo Moro , via Orabona, 4 , 70125 Bari , Italy . Email: ; ; Tel: +39 080 5442750.

View Article and Find Full Text PDF
December 2019

Analysis of Neutrophil Transmigration Through Epithelial Cell Monolayers.

Methods Mol Biol 2020 ;2087:79-91

Department of Microbiology and Immunology, Montana State University, Bozeman, MT, USA.

View Article and Find Full Text PDF
January 2021

Isolation of Neutrophils from Nonhuman Species.

Methods Mol Biol 2020 ;2087:43-59

Department of Microbiology and Immunology, Montana State University, Bozeman, MT, USA.

View Article and Find Full Text PDF
January 2021

The Role of Neutrophils in the Immune System: An Overview.

Methods Mol Biol 2020 ;2087:3-10

Department of Microbiology and Immunology, Montana State University, Bozeman, MT, USA.

View Article and Find Full Text PDF
January 2021

Synthesis, anticancer activity, and molecular modeling of 1,4-naphthoquinones that inhibit MKK7 and Cdc25.

Eur J Med Chem 2019 Dec 18;183:111719. Epub 2019 Sep 18.

Department of Microbiology and Immunology, Montana State University, Bozeman, MT, 59717, USA. Electronic address:

View Article and Find Full Text PDF
December 2019

Neutrophil Immunomodulatory Activity of Natural Organosulfur Compounds.

Molecules 2019 May 10;24(9). Epub 2019 May 10.

Department of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, USA.

View Article and Find Full Text PDF
May 2019

A Novel Gastric Spheroid Co-culture Model Reveals Chemokine-Dependent Recruitment of Human Dendritic Cells to the Gastric Epithelium.

Cell Mol Gastroenterol Hepatol 2019 13;8(1):157-171.e3. Epub 2019 Mar 13.

Department of Microbiology and Immunology, Montana State University, Bozeman, Montana. Electronic address:

View Article and Find Full Text PDF
April 2020

1H-pyrrolo[2,3-b]pyridine: A new scaffold for human neutrophil elastase (HNE) inhibitors.

Bioorg Med Chem 2018 11 27;26(21):5583-5595. Epub 2018 Sep 27.

NEUROFARBA, Pharmaceutical and Nutraceutical Section, University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy.

View Article and Find Full Text PDF
November 2018

The natural sesquiterpene lactones arglabin, grosheimin, agracin, parthenolide, and estafiatin inhibit T cell receptor (TCR) activation.

Phytochemistry 2018 Feb 22;146:36-46. Epub 2017 Dec 22.

Department of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, United States. Electronic address:

View Article and Find Full Text PDF
February 2018

Synthesis and analytical characterization of new thiazol-2-(3H)-ones as human neutrophil elastase (HNE) inhibitors.

Chem Cent J 2017 Dec 6;11(1):127. Epub 2017 Dec 6.

Sezione di Farmaceutica e Nutraceutica, NEUROFARBA, Università degli Studi di Firenze, Via Ugo Schiff 6, 50019, Sesto Fiorentino, Firenze, Italy.

View Article and Find Full Text PDF
December 2017

4-Aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-ones as N-formyl peptide receptor 1 (FPR1) antagonists.

Biochem Pharmacol 2017 10 8;142:120-132. Epub 2017 Jul 8.

Department of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, United States. Electronic address:

View Article and Find Full Text PDF
October 2017

Synthesis and Pharmacological Evaluation of Indole Derivatives as Deaza Analogues of Potent Human Neutrophil Elastase Inhibitors.

Drug Dev Res 2016 09 30;77(6):285-99. Epub 2016 Jul 30.

NEUROFARBA, Sezione di Farmaceutica e Nutraceutica, Università degli Studi di Firenze, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy.

View Article and Find Full Text PDF
September 2016

NET Confusion.

Front Immunol 2016 28;7:259. Epub 2016 Jun 28.

Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Hamilton, MT , USA.

View Article and Find Full Text PDF
July 2016

Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed).

Phytother Res 2016 Aug 24;30(8):1287-97. Epub 2016 May 24.

Department of Microbiology and Immunology, Montana State University, Bozeman, MT, 59717, USA.

View Article and Find Full Text PDF
August 2016

Effects of the neutrophil elastase inhibitor EL-17 in rat adjuvant-induced arthritis.

Rheumatology (Oxford) 2016 07 30;55(7):1285-94. Epub 2016 Mar 30.

Department of Neuroscience, Psychology, Drug Research and Child Health, Neurofarba, Pharmacology and Toxicology Section.

View Article and Find Full Text PDF
July 2016

A novel dual NO-donating oxime and c-Jun N-terminal kinase inhibitor protects against cerebral ischemia-reperfusion injury in mice.

Neurosci Lett 2016 Apr 26;618:45-49. Epub 2016 Feb 26.

Cardiovascular Research Center, Cardiology Division, Massachusetts General Hospital, 149 East 13th Street, Charlestown, MA 02129, USA.

View Article and Find Full Text PDF
April 2016

Antagonism of human formyl peptide receptor 1 with natural compounds and their synthetic derivatives.

Int Immunopharmacol 2016 Aug 15;37:43-58. Epub 2015 Sep 15.

Department of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, United States. Electronic address:

View Article and Find Full Text PDF
August 2016

Cinnoline derivatives as human neutrophil elastase inhibitors.

J Enzyme Inhib Med Chem 2016 Aug 21;31(4):628-39. Epub 2015 Jul 21.

a NEUROFARBA, Sezione di Farmaceutica e Nutraceutica, Università degli Studi di Firenze , Sesto Fiorentino , Italy .

View Article and Find Full Text PDF
August 2016

Aging influences the response of T cells to stimulation by the ellagitannin, oenothein B.

Int Immunopharmacol 2015 Jun 15;26(2):367-77. Epub 2015 Apr 15.

Department of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, United States. Electronic address:

View Article and Find Full Text PDF
June 2015

Anti-Inflammatory Effects and Joint Protection in Collagen-Induced Arthritis after Treatment with IQ-1S, a Selective c-Jun N-Terminal Kinase Inhibitor.

J Pharmacol Exp Ther 2015 Jun 17;353(3):505-16. Epub 2015 Mar 17.

Department of Microbiology and Immunology, Montana State University, Bozeman, Montana (I.A.S., L.N.K., I.K., M.T.Q.); Division of Rheumatology, Allergy, and Immunology, University of California, San Diego School of Medicine, La Jolla, California (D.H., G.S.F.); Department of Chemistry, Altai State Technical University, Barnaul, Russia (A.I.K.); Department of Biotechnology and Organic Chemistry, Tomsk Polytechnic University, Tomsk, Russia (A.I.K.); and A.V. Bogatsky Physico-Chemical Institute, National Academy of Sciences of Ukraine, Odessa, Ukraine (S.A.L.)

View Article and Find Full Text PDF
June 2015

Novel 3-(1H-indol-3-yl)-2-[3-(4-methoxyphenyl)ureido]propanamides as selective agonists of human formyl-peptide receptor 2.

Bioorg Med Chem 2015 Jul 13;23(14):3913-24. Epub 2014 Dec 13.

Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari 'Aldo Moro', via Orabona, 4, 70125 Bari, Italy. Electronic address:

View Article and Find Full Text PDF
July 2015

Antagonism of human formyl peptide receptor 1 (FPR1) by chromones and related isoflavones.

Biochem Pharmacol 2014 Dec 17;92(4):627-41. Epub 2014 Oct 17.

Department of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, USA. Electronic address:

View Article and Find Full Text PDF
December 2014

Unique role of NADPH oxidase 5 in oxidative stress in human renal proximal tubule cells.

Redox Biol 2014 22;2:570-9. Epub 2014 Feb 22.

Division of Nephrology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA ; Department of Physiology, University of Maryland School of Medicine, Baltimore, MD, USA.

View Article and Find Full Text PDF
June 2015

Neutrophil isolation from nonhuman species.

Methods Mol Biol 2014 ;1124:19-37

Department of Immunology and Infectious Diseases, Montana State University, Bozeman, MT, USA.

View Article and Find Full Text PDF
October 2014

The role of neutrophils in the immune system: an overview.

Methods Mol Biol 2014 ;1124:3-10

Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

View Article and Find Full Text PDF
October 2014

Optimization of N-benzoylindazole derivatives as inhibitors of human neutrophil elastase.

J Med Chem 2013 Aug 25;56(15):6259-72. Epub 2013 Jul 25.

NEUROFARBA, Sezione di Farmaceutica e Nutraceutica, Università degli Studi di Firenze, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy.

View Article and Find Full Text PDF
August 2013

Immunomodulatory and hemagglutinating activities of acidic polysaccharides isolated from Combretum racemosum.

Int Immunopharmacol 2013 Mar 1;15(3):628-37. Epub 2013 Feb 1.

Department of Immunology and Infectious Diseases, Montana State University, Bozeman, MT 59717, USA.

View Article and Find Full Text PDF
March 2013

Immunomodulatory activity of polysaccharides isolated from Alchornea cordifolia.

J Ethnopharmacol 2013 Mar 2;146(1):232-42. Epub 2013 Jan 2.

Laboratoire d'Endocrinologie et Biologie de la Reproduction, Université de Cocody-Abidjan, Côte d'Ivoire.

View Article and Find Full Text PDF
March 2013

A NET Outcome.

Front Immunol 2012 5;3:365. Epub 2012 Dec 5.

Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health Hamilton, MT, USA.

View Article and Find Full Text PDF
December 2012

Oenothein B, a cyclic dimeric ellagitannin isolated from Epilobium angustifolium, enhances IFNγ production by lymphocytes.

PLoS One 2012 30;7(11):e50546. Epub 2012 Nov 30.

Department of Immunology and Infectious Diseases, Montana State University, Bozeman, Montana, United States of America.

View Article and Find Full Text PDF
May 2013

Sublytic concentrations of Staphylococcus aureus Panton-Valentine leukocidin alter human PMN gene expression and enhance bactericidal capacity.

J Leukoc Biol 2012 Aug 11;92(2):361-74. Epub 2012 May 11.

Laboratory of Bacterial Pathogenesis, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.

View Article and Find Full Text PDF
August 2012

Effects of the antioxidant drug tempol on renal oxygenation in mice with reduced renal mass.

Am J Physiol Renal Physiol 2012 Jul 4;303(1):F64-74. Epub 2012 Apr 4.

Division of Nephrology and Hypertension, Center for Hypertension, Kidney and Vascular Research, Georgetown University, Washington, DC, USA.

View Article and Find Full Text PDF
July 2012

Identification and characterization of a novel class of c-Jun N-terminal kinase inhibitors.

Mol Pharmacol 2012 Jun 20;81(6):832-45. Epub 2012 Mar 20.

Department of Immunology and Infectious Diseases, Montana State University, Bozeman, MT 59717, USA.

View Article and Find Full Text PDF
June 2012

Design, synthesis and evaluation of N-benzoylindazole derivatives and analogues as inhibitors of human neutrophil elastase.

Bioorg Med Chem 2011 Aug 7;19(15):4460-72. Epub 2011 Jul 7.

Dipartimento di Scienze Farmaceutiche, Università degli Studi di Firenze, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy.

View Article and Find Full Text PDF
August 2011

Differential regulation of Nox1, Nox2 and Nox4 in vascular smooth muscle cells from WKY and SHR.

J Am Soc Hypertens 2011 May-Jun;5(3):137-53. Epub 2011 Mar 17.

Kidney Research Centre, Ottawa Health Research Institute, University of Ottawa, Ontario, Canada.

View Article and Find Full Text PDF
July 2011

Polysaccharides isolated from Açaí fruit induce innate immune responses.

PLoS One 2011 Feb 28;6(2):e17301. Epub 2011 Feb 28.

Department of Immunology and Infectious Diseases, Montana State University, Bozeman, Montana, United States of America.

View Article and Find Full Text PDF
February 2011

Dopamine D1 receptor-mediated inhibition of NADPH oxidase activity in human kidney cells occurs via protein kinase A-protein kinase C cross talk.

Free Radic Biol Med 2011 Apr 28;50(7):832-40. Epub 2010 Dec 28.

Center for Molecular Physiology Research, Children's National Medical Center, Department of Pediatrics, George Washington University School of Medicine, Washington, DC 20010, USA.

View Article and Find Full Text PDF
April 2011

Gastrin-releasing peptide/neuromedin B receptor antagonists PD176252, PD168368, and related analogs are potent agonists of human formyl-peptide receptors.

Mol Pharmacol 2011 Jan 13;79(1):77-90. Epub 2010 Oct 13.

Department of Veterinary Molecular Biology, Montana State University, Bozeman, MT 59717, USA.

View Article and Find Full Text PDF
January 2011

Computational structure-activity relationship analysis of small-molecule agonists for human formyl peptide receptors.

Eur J Med Chem 2010 Nov 15;45(11):5406-19. Epub 2010 Sep 15.

Department of Chemistry, Altai State Technical University, Barnaul 656038, Russia.

View Article and Find Full Text PDF
November 2010

Immunomodulatory activity of oenothein B isolated from Epilobium angustifolium.

J Immunol 2009 Nov 21;183(10):6754-66. Epub 2009 Oct 21.

Departments of Veterinary Molecular Biology, Montana State University, Bozeman, MT 59717, USA.

View Article and Find Full Text PDF
November 2009

Nicotinamide glycolates antagonize CXCR2 activity through an intracellular mechanism.

J Pharmacol Exp Ther 2010 Jan 24;332(1):145-52. Epub 2009 Sep 24.

Syntrix Biosystems, Inc., 215 Clay Street NW, Suite B-5, Auburn, WA 98001, USA.

View Article and Find Full Text PDF
January 2010

Localization of NADPH oxidase in sympathetic and sensory ganglion neurons and perivascular nerve fibers.

Auton Neurosci 2009 Dec 27;151(2):90-7. Epub 2009 Aug 27.

The Neuroscience Program, Michigan State University, East Lansing, MI 48824, USA.

View Article and Find Full Text PDF
December 2009

Inhibition of the human neutrophil NADPH oxidase by Coxiella burnetii.

Microbes Infect 2009 May-Jun;11(6-7):671-9. Epub 2009 Apr 18.

Department of Veterinary Molecular Biology, Montana State University, Bozeman, MT 59717, USA.

View Article and Find Full Text PDF
August 2009

Role of NADPH oxidase in formation and function of multinucleated giant cells.

J Innate Immun 2009 7;1(6):509-26. Epub 2009 Jul 7.

Department of Veterinary Molecular Biology, Montana State University, Bozeman, Montana 59717, USA.

View Article and Find Full Text PDF
May 2010

Complement-fixing activity of fulvic acid from Shilajit and other natural sources.

Phytother Res 2009 Mar;23(3):373-84

Department of Veterinary Molecular Biology, Montana State University, Bozeman, MT 59717, USA.

View Article and Find Full Text PDF
March 2009

Computational structure-activity relationship analysis of non-peptide inducers of macrophage tumor necrosis factor-alpha production.

Bioorg Med Chem 2008 Oct 5;16(20):9302-12. Epub 2008 Sep 5.

Department of Chemistry, Altai State Technical University, Barnaul 656038, Russia.

View Article and Find Full Text PDF
October 2008

Macrophage immunomodulatory activity of polysaccharides isolated from Opuntia polyacantha.

Int Immunopharmacol 2008 Oct 1;8(10):1455-66. Epub 2008 Jul 1.

Department of Veterinary Molecular Biology, Montana State University, Bozeman, MT 59717, United States.

View Article and Find Full Text PDF
October 2008

Molecular analysis of the bovine anaphylatoxin C5a receptor.

J Leukoc Biol 2008 Aug 14;84(2):537-49. Epub 2008 May 14.

Department of Veterinary Molecular Biology, Montana State University, Bozeman, MT 59717, USA.

View Article and Find Full Text PDF
August 2008

Identification of novel formyl peptide receptor-like 1 agonists that induce macrophage tumor necrosis factor alpha production.

Mol Pharmacol 2008 Aug 5;74(2):392-402. Epub 2008 May 5.

Veterinary Molecular Biology, Montana State University, Bozeman, MT 59717, USA.

View Article and Find Full Text PDF
August 2008

Neutrophil isolation from nonhuman species.

Methods Mol Biol 2007 ;412:21-34

Department of Veterinary Molecular Biology, Montana State University, Bozeman, MT, USA.

View Article and Find Full Text PDF
June 2008

Neutrophil methods and protocols. Preface.

Methods Mol Biol 2007 ;412:vii-viii

Department of Veterinary Molecular Biology, Montana State University, Bozeman, USA.

View Article and Find Full Text PDF
June 2008

Fractionation and characterization of biologically-active polysaccharides from Artemisia tripartita.

Phytochemistry 2008 Apr 5;69(6):1359-71. Epub 2008 Mar 5.

Department of Veterinary Molecular Biology, Montana State University, Bozeman, MT 59717, USA.

View Article and Find Full Text PDF
April 2008

Structure-activity relationship analysis of N-benzoylpyrazoles for elastase inhibitory activity: a simplified approach using atom pair descriptors.

Bioorg Med Chem 2008 Mar 15;16(6):2791-802. Epub 2008 Jan 15.

Department of Chemistry, Altai State Technical University, Barnaul 656038, Russia.

View Article and Find Full Text PDF
March 2008

Regulation of proliferation of skeletal muscle precursor cells by NADPH oxidase.

Antioxid Redox Signal 2008 Mar;10(3):559-74

Critical Care Division, Department of Medicine, McGill University Health Centre, Montréal, Québec, Canada.

View Article and Find Full Text PDF
March 2008

Immunomodulatory activity of acidic polysaccharides isolated from Tanacetum vulgare L.

Int Immunopharmacol 2007 Dec 5;7(13):1639-50. Epub 2007 Sep 5.

Department of Veterinary Molecular Biology, Montana State University, Bozeman, MT 59717, USA.

View Article and Find Full Text PDF
December 2007