Mario Cazzola

Mario Cazzola

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Mario Cazzola

Mario Cazzola

Publications by authors named "Mario Cazzola"

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Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes.

Nat Med 2020 Aug 3. Epub 2020 Aug 3.

Computational Oncology Service, Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/s41591-020-1008-zDOI Listing
August 2020

Severe respiratory SARS-CoV2 infection: Does ACE2 receptor matter?

Respir Med 2020 07 25;168:105996. Epub 2020 Apr 25.

Department of Translational Medical Sciences, University of Campania "Luigi Vanvitelli"/Hosp. Monaldi, Naples, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2020.105996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194970PMC
July 2020

The role of triple therapy in the management of COPD.

Expert Rev Clin Pharmacol 2020 Jul 13:1-10. Epub 2020 Jul 13.

Unit of Respiratory Medicine, Unit of Pharmacology, Department Experimental Medicine, Experimental Medicine, University of Rome "Tor Vergata" , Rome, Italy.

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http://dx.doi.org/10.1080/17512433.2020.1787830DOI Listing
July 2020

Introduction to a Review Series on Inherited Anemias.

Authors:
Mario Cazzola

Blood 2020 Jul 23. Epub 2020 Jul 23.

University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1182/blood.2019004083DOI Listing
July 2020

Severe Asthma and Biological Therapy: When, Which, and for Whom.

Pulm Ther 2020 Jun 26;6(1):47-66. Epub 2019 Dec 26.

Respiratory Unit, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1007/s41030-019-00109-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229123PMC
June 2020

Evaluation of fluticasone propionate/salmeterol for the treatment of COPD: a systematic review.

Expert Rev Respir Med 2020 Jun 4;14(6):621-635. Epub 2020 Apr 4.

Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1080/17476348.2020.1743180DOI Listing
June 2020

Emerging muscarinic receptor antagonists for the treatment of asthma.

Expert Opin Emerg Drugs 2020 Jun 17;25(2):123-130. Epub 2020 Jun 17.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata" , Rome, Italy.

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http://dx.doi.org/10.1080/14728214.2020.1758059DOI Listing
June 2020

Introduction to a How I Treat Series on Anemia.

Authors:
Mario Cazzola

Blood 2020 Jun 18. Epub 2020 Jun 18.

University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1182/blood.2020007025DOI Listing
June 2020

The latest on the role of LAMAs in asthma.

J Allergy Clin Immunol 2020 Jun 27. Epub 2020 Jun 27.

Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli," Naples, Italy.

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http://dx.doi.org/10.1016/j.jaci.2020.06.014DOI Listing
June 2020

Pharmacological treatment and current controversies in COPD.

F1000Res 2019 29;8. Epub 2019 Aug 29.

Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.12688/f1000research.19811.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719668PMC
May 2020

Advances in pulmonary drug delivery devices for the treatment of chronic obstructive pulmonary disease.

Expert Opin Drug Deliv 2020 May 16;17(5):635-646. Epub 2020 Mar 16.

Department of Experimental Medicine, Unit of Respiratory Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1080/17425247.2020.1739021DOI Listing
May 2020

Investigational treatments in phase I and II clinical trials: a systematic review in chronic obstructive pulmonary disease (COPD).

Expert Opin Investig Drugs 2020 May 27:1-16. Epub 2020 May 27.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata" , Rome, Italy.

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http://dx.doi.org/10.1080/13543784.2020.1769064DOI Listing
May 2020

SMART and as-needed therapies in mild to severe asthma: a network meta-analysis.

Eur Respir J 2020 May 19. Epub 2020 May 19.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1183/13993003.00625-2020DOI Listing
May 2020

Effect of Erdosteine on COPD Exacerbations in COPD Patients with Moderate Airflow Limitation.

Int J Chron Obstruct Pulmon Dis 2019 2;14:2733-2744. Epub 2019 Dec 2.

Respiratory Division, National Heart And Lung Institute, Imperial College London, London, UK.

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http://dx.doi.org/10.2147/COPD.S221852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896911PMC
April 2020

TSLP Inhibitors for Asthma: Current Status and Future Prospects.

Drugs 2020 Apr;80(5):449-458

Chair of Respiratory Medicine, Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1007/s40265-020-01273-4DOI Listing
April 2020

The effect of doxofylline in asthma and COPD.

Respir Med 2020 04 19;164:105904. Epub 2020 Feb 19.

Chair of Pharmacology, Department of Experimental Medicine, University of Campania, Naples, Italy.

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http://dx.doi.org/10.1016/j.rmed.2020.105904DOI Listing
April 2020

Adding a Second Bronchodilator in COPD: A Meta-Analysis on the Risk of Specific Cardiovascular Serious Adverse Events of Tiotropium/Olodaterol Fixed-Dose Combination.

COPD 2020 Apr 6;17(2):215-223. Epub 2020 Apr 6.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1080/15412555.2020.1749252DOI Listing
April 2020

New perspectives on the role of muscarinic antagonists in asthma therapy.

Expert Rev Respir Med 2020 Apr 26:1-8. Epub 2020 Apr 26.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1080/17476348.2020.1758069DOI Listing
April 2020

Beclomethasone dipropionate, formoterol fumarate and glycopyrronium bromide: Synergy of triple combination therapy on human airway smooth muscle ex vivo.

Br J Pharmacol 2020 Mar 29;177(5):1150-1163. Epub 2020 Jan 29.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1111/bph.14909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042115PMC
March 2020

α-Antitrypsin deficiency and chronic respiratory disorders.

Eur Respir Rev 2020 Mar 12;29(155). Epub 2020 Feb 12.

Unit of Pharmacology, Dept Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.1183/16000617.0073-2019DOI Listing
March 2020

Essential Thrombocythemia.

N Engl J Med 2020 03;382(12):e21

Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

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http://dx.doi.org/10.1056/NEJMc1917586DOI Listing
March 2020

Distinct and convergent consequences of splice factor mutations in myelodysplastic syndromes.

Am J Hematol 2020 02 18;95(2):133-143. Epub 2019 Nov 18.

Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1002/ajh.25673DOI Listing
February 2020

A long-term clinical trial on the efficacy and safety profile of doxofylline in Asthma: The LESDA study.

Pulm Pharmacol Ther 2020 02 26;60:101883. Epub 2019 Dec 26.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1016/j.pupt.2019.101883DOI Listing
February 2020

A review of the pharmacokinetics of M muscarinic receptor antagonists used for the treatment of asthma.

Expert Opin Drug Metab Toxicol 2020 Feb 30;16(2):143-148. Epub 2020 Jan 30.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1080/17425255.2020.1716730DOI Listing
February 2020

Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes.

N Engl J Med 2020 01;382(2):140-151

From Service d'Hématologie Séniors, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris and Université Paris 7, Paris (P.F., L.A.), Service des Maladies du Sang, Hôpital Huriez, Centre Hospitalier Universitaire (CHU) de Lille, Lille (B.Q.), the Department of Internal Medicine, CHU Toulouse, Institut Universitaire du Cancer de Toulouse, Toulouse (O.B.-R.), and Université Cote d'Azur, Département d'Hématologie Clinique, CHU Nice, Nice (T.C.) - all in France; Medical Clinic and Policlinic 1, Hematology and Cellular Therapy, Leipzig University Hospital, Leipzig (U.P.), Klinik für Hämatologie, Onkologie, and Klinische Immunologie, Universitätsklinik Düsseldorf, Düsseldorf (U.G.), and Klinik und Poliklinik für Innere Medizin III, Technische Universität München, Munich (K.S.G.) - all in Germany; the Department of Haemato-Oncology, King's College London, London (G.J.M.), Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford (P.V.), and the Department of Haematology, Leeds Teaching Hospitals NHS Trust, Leeds (D.B.) - all in the United Kingdom; the Department of Leukemia, University of Texas M.D. Anderson Cancer Center, Houston (G.G.-M.); Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto (R.B.); MDS Unit, Azienda Ospedaliero Universitaria Careggi, University of Florence, Florence (V.S.), the Department of Oncology and Hematology, S. Orsola-Malpighi University Hospital, Bologna (C.F.), the University of Pavia, Fondazione IRCCS Policlinico S. Matteo, Pavia (M.C.), the Hematology Unit, Santi Antonio e Biagio e Cesare Arrigo Hospital, Alessandria (F.S., V.G.), and Dipartimento Biomedicina e Prevenzione, University of Rome Tor Vergata, Rome (M.-T.V.) - all in Italy; the Hematology Department, University Hospital of Salamanca, Institute of Biomedical Research of Salamanca, Salamanca (M.D.-C.), Unidad de Hematología, Hospital Universitario Virgen del Rocío, Seville (J.F.F.), and the Department of Hematology, Hospital Universitario Cruces, Vizcaya (B.A.) - all in Spain; the Department of Hematology Science, School of Medicine, Ankara University, Ankara, Turkey (O.I.); the Department of Hematology and Medical Oncology, Cleveland Clinic, Cleveland (M.A.S.); the Department of Hematology, Algemeen Ziekenhuis Sint-Jan, Bruges (D.S.), and Universitair Ziekenhuis Gent, Ghent (D.M.) - both in Belgium; the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore (A.E.D.); the Division of Hematology-Oncology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center (J.G.J.), and Albert Einstein College of Medicine (A.V.) - both in New York; the Department of Hematology, University Medical Center of Groningen, University of Groningen, Groningen, the Netherlands (E.V.); Stanford University Cancer Center, Stanford, CA (P.L.G.); the Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, Stockholm (E.H.-L.); the Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, CT (A.M.Z.); Vanderbilt University School of Medicine, Vanderbilt-Ingram Cancer Center, Nashville (M.R.S.); Celgene, Summit, NJ (A.L., J.Z., A.R., D.R.D.); Celgene International, Boudry, Switzerland (A.B.); Acceleron Pharma, Cambridge, MA (P.G.L., M.L.S.); and Moffitt Cancer Center, Tampa, FL (R.S.K., A.F.L.).

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http://dx.doi.org/10.1056/NEJMoa1908892DOI Listing
January 2020

Efficacy and cardiovascular safety profile of dual bronchodilation therapy in chronic obstructive pulmonary disease: A bidimensional comparative analysis across fixed-dose combinations.

Pulm Pharmacol Ther 2019 12 11;59:101841. Epub 2019 Sep 11.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1016/j.pupt.2019.101841DOI Listing
December 2019

Impact of ICS/LABA and LABA/LAMA FDCs on functional and clinical outcomes in COPD: A network meta-analysis.

Pulm Pharmacol Ther 2019 12 19;59:101855. Epub 2019 Oct 19.

Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata", Rome, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S10945539193016
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http://dx.doi.org/10.1016/j.pupt.2019.101855DOI Listing
December 2019

Optimizing the Development Strategy of Combination Therapy in Respiratory Medicine: From Isolated Airways to Patients.

Adv Ther 2019 12 25;36(12):3291-3298. Epub 2019 Oct 25.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1007/s12325-019-01119-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6860506PMC
December 2019

The future of bronchodilation: looking for new classes of bronchodilators.

Eur Respir Rev 2019 Dec 23;28(154). Epub 2019 Dec 23.

Dept of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.1183/16000617.0095-2019DOI Listing
December 2019

Triple Therapy Versus Dual Bronchodilation and Inhaled Corticosteroids/Long-Acting β-Agonists in COPD: Accumulating Evidence from Network Meta-Analyses.

Pulm Ther 2019 Dec 2;5(2):117-126. Epub 2019 Nov 2.

Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.1007/s41030-019-00102-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6967256PMC
December 2019

A potential role of triple therapy for asthma patients.

Expert Rev Respir Med 2019 11 1;13(11):1079-1085. Epub 2019 Sep 1.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata" , Rome , Italy.

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http://dx.doi.org/10.1080/17476348.2019.1657408DOI Listing
November 2019

Pharmacokinetics and pharmacodynamics of inhaled corticosteroids for asthma treatment.

Pulm Pharmacol Ther 2019 10 23;58:101828. Epub 2019 Jul 23.

University of Rome "Tor Vergata", Department of Experimental Medicine, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.pupt.2019.101828DOI Listing
October 2019

Evolving Concepts in Chronic Obstructive Pulmonary Disease Blood-Based Biomarkers.

Mol Diagn Ther 2019 10;23(5):603-614

Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1007/s40291-019-00413-1DOI Listing
October 2019

Ensifentrine (RPL554): an investigational PDE3/4 inhibitor for the treatment of COPD.

Expert Opin Investig Drugs 2019 Oct 1;28(10):827-833. Epub 2019 Sep 1.

Unit of Pharmacology, Dept. Experimental Medicine, University of Campania "Luigi Vanvitelli" , Naples , Italy.

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http://dx.doi.org/10.1080/13543784.2019.1661990DOI Listing
October 2019

Ultra-LABAs for the treatment of asthma.

Respir Med 2019 09 12;156:47-52. Epub 2019 Aug 12.

Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.1016/j.rmed.2019.08.005DOI Listing
September 2019

Chronic Obstructive Pulmonary Disease and Stroke.

COPD 2018 Jun-Aug;15(4):405-413. Epub 2018 May 10.

d University General Hospital , Department of Thoracic Medicine, Stavrakia , Heraklion , Greece.

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http://dx.doi.org/10.1080/15412555.2018.1464551DOI Listing
August 2019

Efficacy and safety profile of doxofylline compared to theophylline in asthma: a meta-analysis.

Multidiscip Respir Med 2019 3;14:25. Epub 2019 Aug 3.

3Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.1186/s40248-019-0189-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679461PMC
August 2019

Monoclonal antibodies for severe asthma: Pharmacokinetic profiles.

Respir Med 2019 07 13;153:3-13. Epub 2019 May 13.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2019.05.005DOI Listing
July 2019

Thiol-Based Drugs in Pulmonary Medicine: Much More than Mucolytics.

Trends Pharmacol Sci 2019 07 27;40(7):452-463. Epub 2019 May 27.

Unit of Pharmacology, Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy.

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http://dx.doi.org/10.1016/j.tips.2019.04.015DOI Listing
July 2019

Pharmacological characterization of the interaction between tiotropium bromide and olodaterol on human bronchi and small airways.

Pulm Pharmacol Ther 2019 06 12;56:39-50. Epub 2019 Mar 12.

Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.1016/j.pupt.2019.03.004DOI Listing
June 2019

Spectrum of mutations in primary myelofibrosis: prognostic impact of the p.G646Wfs*12 mutation.

Blood 2019 06 10;133(26):2802-2808. Epub 2019 May 10.

Centro di Ricerca e Innovazione per le Malattie Mieloproliferative (CRIMM), Dipartimento di Medicina Sperimentale e Clinica, Azienda Ospedaliera Universitaria Careggi, and.

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http://dx.doi.org/10.1182/blood.2018879536DOI Listing
June 2019

Cardiovascular Disease in Chronic Respiratory Disorders and Beyond.

J Am Coll Cardiol 2019 05;73(17):2178-2180

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata," Rome, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S07351097193392
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http://dx.doi.org/10.1016/j.jacc.2018.11.068DOI Listing
May 2019

Bronchodilators in subjects with asthma-related comorbidities.

Respir Med 2019 05 3;151:43-48. Epub 2019 Apr 3.

Chair of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.1016/j.rmed.2019.04.001DOI Listing
May 2019

Response.

Chest 2019 05;155(5):1079-1080

Department of Experimental Medicine, Unit of Respiratory Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.1016/j.chest.2019.01.028DOI Listing
May 2019

Efficacy and safety profile of mucolytic/antioxidant agents in chronic obstructive pulmonary disease: a comparative analysis across erdosteine, carbocysteine, and N-acetylcysteine.

Respir Res 2019 May 27;20(1):104. Epub 2019 May 27.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133, Rome, Italy.

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http://dx.doi.org/10.1186/s12931-019-1078-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537173PMC
May 2019

Adding a LAMA to ICS/LABA Therapy: A Meta-analysis of Triple Combination Therapy in COPD.

Chest 2019 04 17;155(4):758-770. Epub 2019 Jan 17.

Department of Experimental Medicine, Unit of Respiratory Medicine, University of Rome "Tor Vergata," Rome, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S00123692193001
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http://dx.doi.org/10.1016/j.chest.2018.12.016DOI Listing
April 2019

Inhaled therapies and cardiovascular risk in patients with chronic obstructive pulmonary disease.

Expert Opin Pharmacother 2019 04 1;20(6):737-750. Epub 2019 Feb 1.

b Division of Respiratory Medicine , University Hospital "Tor Vergata" , Rome , Italy.

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http://dx.doi.org/10.1080/14656566.2019.1570133DOI Listing
April 2019

Introduction to a review series on transfusion medicine.

Authors:
Mario Cazzola

Blood 2019 04 26;133(17):1793-1794. Epub 2019 Feb 26.

Associate Editor, Blood.

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http://dx.doi.org/10.1182/blood-2019-01-888248DOI Listing
April 2019

LABA/LAMA fixed-dose combinations in patients with COPD: a systematic review.

Int J Chron Obstruct Pulmon Dis 2018;13:3115-3130. Epub 2018 Oct 4.

Department of Health Sciences, Università degli Studi di Milano, Respiratory Unit, Papa Giovanni XXIII Hospital, Bergamo, Italy.

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http://dx.doi.org/10.2147/COPD.S170606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174911PMC
March 2019

Clonal monocytosis of clinical significance.

Authors:
Mario Cazzola

Blood 2019 03;133(12):1271-1272

University of Pavia.

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http://dx.doi.org/10.1182/blood-2019-01-896084DOI Listing
March 2019

Introduction to a review series on iron metabolism and its disorders.

Blood 2019 01 14;133(1):1-2. Epub 2018 Nov 14.

Associate Editor, Blood.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood-2018-10
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http://dx.doi.org/10.1182/blood-2018-10-876466DOI Listing
January 2019

Triple therapy single and dual long-acting bronchodilator therapy in COPD: a systematic review and meta-analysis.

Eur Respir J 2018 12 13;52(6). Epub 2018 Dec 13.

Unit of Pharmacology, Dept of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.01586
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http://dx.doi.org/10.1183/13993003.01586-2018DOI Listing
December 2018

Current pharmacotherapeutic options for pediatric lower respiratory tract infections with a focus on antimicrobial agents.

Expert Opin Pharmacother 2018 Dec 25;19(18):2043-2053. Epub 2018 Oct 25.

b Department of Experimental Medicine and Surgery , University of Rome Tor Vergata , Rome , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14656566.2018.1
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http://dx.doi.org/10.1080/14656566.2018.1534957DOI Listing
December 2018

Varenicline for long term smoking cessation in patients with COPD.

Pulm Pharmacol Ther 2018 12 3;53:116-120. Epub 2018 Nov 3.

Department of Experimental Medicine and Surgery, Chair of Respiratory Medicine, University of Rome 'Tor Vergata', Via Montpellier, 100133, Rome, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S10945539183004
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http://dx.doi.org/10.1016/j.pupt.2018.11.001DOI Listing
December 2018

An inhaled "bifunctional" dual PDE3/4 inhibitor provides additional short-term improvements in lung function compared to existing classes of bronchodilator: implications for future treatment of COPD.

Eur Respir J 2018 11 1;52(5). Epub 2018 Nov 1.

Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, UK.

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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.01675
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http://dx.doi.org/10.1183/13993003.01675-2018DOI Listing
November 2018

Ensifentrine (RPL554): an inhaled 'bifunctional' dual PDE3/4 inhibitor for the treatment of asthma and chronic obstructive pulmonary disease.

Pharm Pat Anal 2018 Nov 18;7(6):249-257. Epub 2019 Jan 18.

Unit of Pharmacology, Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy.

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http://dx.doi.org/10.4155/ppa-2018-0030DOI Listing
November 2018

Indacaterol/Glycopyrronium in Clinical Practice: The Italian Experience.

Authors:
Mario Cazzola

Respiration 2018;95 Suppl 1:1-2. Epub 2018 Apr 27.

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http://dx.doi.org/10.1159/000486881DOI Listing
October 2018

Tiotropium could provide benefits in the early stage of COPD, but further studies are needed.

BMJ Evid Based Med 2018 10 27;23(5):183-184. Epub 2018 Jun 27.

Department of Experimental Medicine and Surgery, Universita degli Studi di Roma Tor Vergata, Rome, Italy.

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http://ebm.bmj.com/lookup/doi/10.1136/bmjebm-2018-110940
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http://dx.doi.org/10.1136/bmjebm-2018-110940DOI Listing
October 2018

Pharmacokinetic considerations concerning the use of bronchodilators in the treatment of chronic obstructive pulmonary disease.

Expert Opin Drug Metab Toxicol 2018 Oct 9;14(10):1101-1111. Epub 2018 Oct 9.

c Department of Experimental Medicine and Surgery , University of Rome Tor Vergata , Rome , Italy.

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http://dx.doi.org/10.1080/17425255.2018.1530215DOI Listing
October 2018

POINT: Should LAMA/LABA Combination Therapy Be Used as Initial Maintenance Treatment for COPD? Yes.

Chest 2018 10;154(4):746-748

Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S00123692183097
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http://dx.doi.org/10.1016/j.chest.2018.06.022DOI Listing
October 2018

Rebuttal From Drs Cazzola and Matera.

Chest 2018 10;154(4):751-752

Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.1016/j.chest.2018.06.023DOI Listing
October 2018

Pregnancy outcome and management of 25 pregnancies in women with polycythemia vera.

Am J Hematol 2018 09 31;93(9):E234-E235. Epub 2018 Aug 31.

First Medical Clinic, Department of Medicine-DIMED, University of Padova, Padova, Italy.

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http://dx.doi.org/10.1002/ajh.25210DOI Listing
September 2018

Emerging antibacterial and antiviral drugs for treating respiratory tract infections.

Expert Opin Emerg Drugs 2018 09 30;23(3):185-199. Epub 2018 Jul 30.

a Department of Pathophysiology and Transplantation , Università degli Studi di Milano, Internal Medicine Department, Respiratory Unit and Regional Adult Cystic Fibrosis Center,IRCCS Fondazione Cà Granda Ospedale Maggiore Policlinico , Milan , Italy.

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http://dx.doi.org/10.1080/14728214.2018.1504020DOI Listing
September 2018

Impact of doxofylline in COPD: A pairwise meta-analysis.

Pulm Pharmacol Ther 2018 08 26;51:1-9. Epub 2018 Apr 26.

Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S10945539183009
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http://dx.doi.org/10.1016/j.pupt.2018.04.010DOI Listing
August 2018

Multifaceted activity of N-acetyl-l-cysteine in chronic obstructive pulmonary disease.

Expert Rev Respir Med 2018 08 17;12(8):693-708. Epub 2018 Jul 17.

a Department of Experimental Medicine and Surgery , University of Rome Tor Vergata , Rome , Italy.

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https://www.tandfonline.com/doi/full/10.1080/17476348.2018.1
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http://dx.doi.org/10.1080/17476348.2018.1495562DOI Listing
August 2018

Benefits and risks of JAK inhibition.

Blood 2018 08;132(7):675-676

University of Pavia.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood-2018-07
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http://dx.doi.org/10.1182/blood-2018-07-858720DOI Listing
August 2018

N-Acetylcysteine protects human bronchi by modulating the release of neurokinin A in an ex vivo model of COPD exacerbation.

Biomed Pharmacother 2018 Jul 24;103:1-8. Epub 2018 Apr 24.

Department of Experimental Medicine, Unit of Pharmacology, Second University of Naples, Naples, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2018.04.011DOI Listing
July 2018

Senolytic drugs in respiratory medicine: is it an appropriate therapeutic approach?

Expert Opin Investig Drugs 2018 07 4;27(7):573-581. Epub 2018 Jul 4.

a Chair of Respiratory Medicine, Department of Experimental Medicine and Surgery , University of Rome "Tor Vergata" , Rome , Italy.

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http://dx.doi.org/10.1080/13543784.2018.1492548DOI Listing
July 2018

Pharmacological mechanisms leading to synergy in fixed-dose dual bronchodilator therapy.

Curr Opin Pharmacol 2018 06 4;40:95-103. Epub 2018 Apr 4.

Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata", Rome, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S14714892183001
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http://dx.doi.org/10.1016/j.coph.2018.03.011DOI Listing
June 2018

The safety of dual bronchodilation on cardiovascular serious adverse events in COPD.

Expert Opin Drug Saf 2018 06 14;17(6):589-596. Epub 2018 May 14.

a Department of Experimental Medicine and Surgery , University of Rome Tor Vergata , Rome , Italy.

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http://dx.doi.org/10.1080/14740338.2018.1472232DOI Listing
June 2018

Efficacy and safety profile of xanthines in COPD: a network meta-analysis.

Eur Respir Rev 2018 Jun 2;27(148). Epub 2018 May 2.

Dept of Experimental Medicine, Unit of Pharmacology, University of Campania Luigi Vanvitelli, Naples, Italy.

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http://dx.doi.org/10.1183/16000617.0010-2018DOI Listing
June 2018

Editorial overview: Respiratory: Pulmonary pharmacology - It is time for a breath of fresh air.

Curr Opin Pharmacol 2018 06 30;40:iv-viii. Epub 2018 May 30.

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http://dx.doi.org/10.1016/j.coph.2018.05.011DOI Listing
June 2018

Combining Dual Bronchodilation and β-Blockade in Patients With an Overlap Between COPD and Cardiovascular Diseases.

Chest 2018 06;153(6):1289-1291

Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli, Naples, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S00123692183022
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http://dx.doi.org/10.1016/j.chest.2018.01.032DOI Listing
June 2018

Beclomethasone dipropionate and formoterol fumarate synergistically interact in hyperresponsive medium bronchi and small airways.

Respir Res 2018 04 12;19(1):65. Epub 2018 Apr 12.

Unit of Respiratory Medicine, Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata", Via Montpellier 1, 00133, Rome, Italy.

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http://dx.doi.org/10.1186/s12931-018-0770-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897944PMC
April 2018