Manfred Alsheimer

Manfred Alsheimer

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Manfred Alsheimer

Manfred Alsheimer

Publications by authors named "Manfred Alsheimer"

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The testis specific LINC component SUN3 is essential for sperm head shaping during mouse spermiogenesis.

J Biol Chem 2020 Mar 10. Epub 2020 Mar 10.

School of Life Sciences, University of Science & Technology of China.

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http://dx.doi.org/10.1074/jbc.RA119.012375DOI Listing
March 2020

Analysis of Meiotic Telomere Behavior in the Mouse.

Methods Mol Biol 2016 ;1411:195-208

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.

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http://dx.doi.org/10.1007/978-1-4939-3530-7_12DOI Listing
December 2017

Evolutionary history of the mammalian synaptonemal complex.

Chromosoma 2016 06 12;125(3):355-60. Epub 2016 Mar 12.

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, 97074, Würzburg, Germany.

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http://dx.doi.org/10.1007/s00412-016-0583-8DOI Listing
June 2016

Structural and functional adaptations of the mammalian nuclear envelope to meet the meiotic requirements.

Nucleus 2015 12;6(2):93-101. Epub 2015 Feb 12.

a Department of Cell and Developmental Biology ; Biocenter University Würzburg ; Würzburg , Germany.

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http://www.tandfonline.com/doi/full/10.1080/19491034.2015.10
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http://dx.doi.org/10.1080/19491034.2015.1004941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615672PMC
January 2016

The LINC complex component Sun4 plays a crucial role in sperm head formation and fertility.

Biol Open 2015 Nov 30;4(12):1792-802. Epub 2015 Nov 30.

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, Würzburg D-97074, Germany

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http://bio.biologists.org/cgi/doi/10.1242/bio.015768
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http://dx.doi.org/10.1242/bio.015768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736043PMC
November 2015

Protein SYCP2 is an ancient component of the metazoan synaptonemal complex.

Cytogenet Genome Res 2014 28;144(4):299-305. Epub 2015 Mar 28.

Department of Cell and Developmental Biology, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1159/000381080DOI Listing
June 2015

CDK2 regulates nuclear envelope protein dynamics and telomere attachment in mouse meiotic prophase.

J Cell Sci 2015 Jan 6;128(1):88-99. Epub 2014 Nov 6.

Unidad de Biología Celular, Departamento de Biología, Facultad de Ciencias, Universidad Autónoma de Madrid, E-28049 Madrid, Spain

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http://dx.doi.org/10.1242/jcs.154922DOI Listing
January 2015

Mouse CCDC79 (TERB1) is a meiosis-specific telomere associated protein.

BMC Cell Biol 2014 May 22;15:17. Epub 2014 May 22.

Institute of Physiological Chemistry, Technische Universität Dresden, Fiedlerstr, 42, Dresden 01307, Germany.

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http://dx.doi.org/10.1186/1471-2121-15-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038382PMC
May 2014

Analysis of meiosis in SUN1 deficient mice reveals a distinct role of SUN2 in mammalian meiotic LINC complex formation and function.

PLoS Genet 2014 Feb 27;10(2):e1004099. Epub 2014 Feb 27.

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1371/journal.pgen.1004099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937131PMC
February 2014

Phylogenies of central element proteins reveal the dynamic evolutionary history of the mammalian synaptonemal complex: ancient and recent components.

Genetics 2013 Nov 11;195(3):781-93. Epub 2013 Sep 11.

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, 97074 Würzburg, Germany.

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http://dx.doi.org/10.1534/genetics.113.156679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813864PMC
November 2013

LINCing the nuclear envelope to gametogenesis.

Curr Top Dev Biol 2013 ;102:127-57

Department of Physiology, Wayne State University Medical School, Detroit, Michigan, USA.

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http://dx.doi.org/10.1016/B978-0-12-416024-8.00005-2DOI Listing
September 2013

The meiotic nuclear lamina regulates chromosome dynamics and promotes efficient homologous recombination in the mouse.

PLoS Genet 2013 31;9(1):e1003261. Epub 2013 Jan 31.

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1371/journal.pgen.1003261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561109PMC
May 2013

A truncated lamin A in the Lmna -/- mouse line: implications for the understanding of laminopathies.

Nucleus 2012 Sep-Oct;3(5):463-74. Epub 2012 Aug 16.

Department of Cell and Developmental Biology, Biocenter, University of Würzburg; Würzburg, Germany.

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http://dx.doi.org/10.4161/nucl.21676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474667PMC
February 2013

Hydra meiosis reveals unexpected conservation of structural synaptonemal complex proteins across metazoans.

Proc Natl Acad Sci U S A 2012 Oct 24;109(41):16588-93. Epub 2012 Sep 24.

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, D-97074 Würzburg, Germany.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1206875109
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http://dx.doi.org/10.1073/pnas.1206875109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478637PMC
October 2012

The mammalian synaptonemal complex: protein components, assembly and role in meiotic recombination.

Exp Cell Res 2012 Jul 28;318(12):1340-6. Epub 2012 Feb 28.

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1016/j.yexcr.2012.02.018DOI Listing
July 2012

Dynamic properties of meiosis-specific lamin C2 and its impact on nuclear envelope integrity.

Nucleus 2010 May-Jun;1(3):273-83. Epub 2010 Mar 15.

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, Germany.

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http://dx.doi.org/10.4161/nucl.1.3.11800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027034PMC
January 2012

Expression of individual mammalian Sun1 isoforms depends on the cell type.

Commun Integr Biol 2011 Jul 1;4(4):440-2. Epub 2011 Jul 1.

Department of Cell and Developmental Biology; Biocenter; University of Würzburg; Am Hubland, Würzburg Germany.

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http://dx.doi.org/10.4161/cib.4.4.15369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181515PMC
July 2011

Mammalian sperm head formation involves different polarization of two novel LINC complexes.

PLoS One 2010 Aug 10;5(8):e12072. Epub 2010 Aug 10.

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, Würzburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012072PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919408PMC
August 2010

Cohesin SMC1beta protects telomeres in meiocytes.

J Cell Biol 2009 Oct;187(2):185-99

Institute of Physiological Chemistry, Medical Faculty Carl Gustav Carus, Dresden University of Technology, 01307 Dresden, Germany.

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http://dx.doi.org/10.1083/jcb.200808016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768837PMC
October 2009

Protein SYCP2 provides a link between transverse filaments and lateral elements of mammalian synaptonemal complexes.

Chromosoma 2009 Apr 26;118(2):259-67. Epub 2008 Nov 26.

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, Am Hubland, Germany.

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http://link.springer.com/10.1007/s00412-008-0194-0
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http://dx.doi.org/10.1007/s00412-008-0194-0DOI Listing
April 2009

Transmembrane protein Sun2 is involved in tethering mammalian meiotic telomeres to the nuclear envelope.

Proc Natl Acad Sci U S A 2007 May 23;104(18):7426-31. Epub 2007 Apr 23.

Department of Cell and Developmental Biology, Biocenter of the University of Würzburg, D-97074 Würzburg, Germany.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0609198104
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http://dx.doi.org/10.1073/pnas.0609198104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1863442PMC
May 2007

Synaptonemal complex protein SYCP3: Conserved polymerization properties among vertebrates.

Biochim Biophys Acta 2007 May 24;1774(5):595-602. Epub 2007 Mar 24.

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.

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http://dx.doi.org/10.1016/j.bbapap.2007.03.008DOI Listing
May 2007

Nuclear envelope remodeling during mouse spermiogenesis: postmeiotic expression and redistribution of germline lamin B3.

Exp Cell Res 2005 Jul 26;307(2):285-91. Epub 2005 Apr 26.

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1016/j.yexcr.2005.03.023DOI Listing
July 2005

Dynamic properties of germ line-specific lamin B3: the role of the shortened rod domain.

Eur J Cell Biol 2005 Jul;84(7):649-62

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, Germany.

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http://dx.doi.org/10.1016/j.ejcb.2005.03.001DOI Listing
July 2005

The myristoylation site of meiotic lamin C2 promotes local nuclear membrane growth and the formation of intranuclear membranes in somatic cultured cells.

Eur J Cell Biol 2005 Jun;84(6):637-46

Division of Electron Microscopy, Biocenter of the University of Würzburg, Am Hubland, D-97074 Würzburg, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S017193350500019
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http://dx.doi.org/10.1016/j.ejcb.2004.12.027DOI Listing
June 2005

The mammalian gene pecanex 1 is differentially expressed during spermatogenesis.

Biochim Biophys Acta 2005 Apr;1728(1-2):34-43

Unidad Asociada Biología Molecular (IIBCE), Facultad de Ciencias, Montevideo, Uruguay; Departamento de Biología Molecular, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay.

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http://dx.doi.org/10.1016/j.bbaexp.2005.01.010DOI Listing
April 2005

The cancer/testis antigen CAGE-1 is a component of the acrosome of spermatids and spermatozoa.

Eur J Cell Biol 2005 Mar;84(2-3):445-52

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1016/j.ejcb.2004.11.003DOI Listing
March 2005

Mammalian protein SCP1 forms synaptonemal complex-like structures in the absence of meiotic chromosomes.

Mol Biol Cell 2005 Jan 20;16(1):212-7. Epub 2004 Oct 20.

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1091/mbc.e04-09-0771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC539165PMC
January 2005

Disruption of spermatogenesis in mice lacking A-type lamins.

J Cell Sci 2004 Mar;117(Pt 7):1173-8

Department of Cell and Developmental Biology, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.

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http://dx.doi.org/10.1242/jcs.00975DOI Listing
March 2004

Mammalian meiotic telomeres: composition and ultrastructure in telomerase-deficient mice.

Eur J Cell Biol 2002 Jun;81(6):335-40

Department of Immunology and Oncology, National Centre of Biotechnology, CSIC, Madrid, Spain.

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http://dx.doi.org/10.1078/0171-9335-00259DOI Listing
June 2002