Publications

Nintedanib inhibits macrophage activation and ameliorates vascular and fibrotic manifestations in the Fra2 mouse model of systemic sclerosis.
Ann Rheum Dis 2017 Nov 16;76(11):1941-1948. Epub 2017 Aug 16.
Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.

Nintedanib reduces radiation-induced microscopic lung fibrosis but this cannot be monitored by CT imaging: A preclinical study with a high precision image-guided irradiator.
Radiother Oncol 2017 Sep 31;124(3):482-487. Epub 2017 Jul 31.
Department of Radiation Oncology (Maastro), GROW - School for Oncology and Developmental Biology, Maastricht University Medical Center, The Netherlands. Electronic address:

Effects of nintedanib on the microvascular architecture in a lung fibrosis model.
Angiogenesis 2017 Aug 10;20(3):359-372. Epub 2017 Mar 10.
Institute of Functional and Clinical Anatomy, University Medical Center of the Johannes Gutenberg University Mainz, Johann-Joachim-Becher-Weg 13, 55128, Mainz, Germany.

Tyrosine kinase inhibitor BIBF1000 does not hamper right ventricular pressure adaptation in rats.
Am J Physiol Heart Circ Physiol 2016 Sep 24;311(3):H604-12. Epub 2016 Jun 24.
Department of Pulmonology, VU University Medical Center, Institute for Cardiovascular Research, Amsterdam, The Netherlands;

Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis.
Ann Rheum Dis 2016 May 9;75(5):883-90. Epub 2015 Apr 9.
Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.

Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis.
J Pharmacol Exp Ther 2014 May 20;349(2):209-20. Epub 2014 Feb 20.
Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany (L.W., A.H.); UMR7355, INEM, CNRS and University of Orleans, Orleans, France (I.M., V.Q., B.R.); and IIDMM, University of Cape Town, Cape Town, Republic of South Africa (B.R.).

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