Luis A Lopez-Fernandez

Luis A Lopez-Fernandez

UNVERIFIED PROFILE

Are you Luis A Lopez-Fernandez?   Register this Author

Register author
Luis A Lopez-Fernandez

Luis A Lopez-Fernandez

Publications by authors named "Luis A Lopez-Fernandez"

Are you Luis A Lopez-Fernandez?   Register this Author

45Publications

557Reads

9Profile Views

Differential Expression of Genes and on Circulating CD4+ T Cells in Multiple Sclerosis and Crohn's Disease.

Int J Mol Sci 2020 Jan 20;21(2). Epub 2020 Jan 20.

Servicio de Farmacia, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms21020676DOI Listing
January 2020

Genetic predictors of long-term response and trough levels of infliximab in crohn's disease.

Pharmacol Res 2019 Nov 9;149:104478. Epub 2019 Oct 9.

Department of Pharmacy, Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain; Spanish Clinical Research Network (SCReN), Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2019.104478DOI Listing
November 2019

Comments on: "Clinical utility of ABCB1 genotyping for preventing toxicity in treatment with irinotecan".

Pharmacol Res 2019 07 26;145:104288. Epub 2019 May 26.

Hospital General Universitario Gregorio Marañoín, Instituto de Investigacioín Sanitaria Gregorio Marañoín (IiSGM), Madrid, Spain; Hospital General Universitario Gregorio Marañoín, Instituto de Investigacioín Sanitaria Gregorio Marañoín (IiSGM), Madrid, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2019.104288DOI Listing
July 2019

ATP-Binding Cassette Transporters in the Clinical Implementation of Pharmacogenetics.

J Pers Med 2018 Dec 5;8(4). Epub 2018 Dec 5.

Pharmacy Department, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio, 28007 Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/jpm8040040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313650PMC
December 2018

Clinical utility of ABCB1 genotyping for preventing toxicity in treatment with irinotecan.

Pharmacol Res 2018 10 11;136:133-139. Epub 2018 Sep 11.

Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain; Spanish Clinical Research Network (SCReN), Spain. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10436618183077
Publisher Site
http://dx.doi.org/10.1016/j.phrs.2018.08.026DOI Listing
October 2018

Using pharmacogenetics to prevent severe adverse reactions to capecitabine.

Pharmacogenomics 2017 08 26;18(13):1199-1213. Epub 2017 Jul 26.

Servicio de Farmacia, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pgs-2017-0102DOI Listing
August 2017

Identification of new SNPs associated with severe toxicity to capecitabine.

Pharmacol Res 2017 Jun 27;120:133-137. Epub 2017 Mar 27.

Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2017.03.021DOI Listing
June 2017

Cost-effectiveness of screening for DPYD polymorphisms to prevent neutropenia in cancer patients treated with fluoropyrimidines.

Pharmacogenomics 2016 06 1;17(9):979-84. Epub 2016 Jun 1.

Department of Pharmacy, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, Doctor Esquerdo 46, 28007 Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pgs-2016-0006DOI Listing
June 2016

Identification of genetic variants associated with capecitabine-induced hand-foot syndrome through integration of patient and cell line genomic analyses.

Pharmacogenet Genomics 2014 May;24(5):231-7

aSection of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, Illinois, USA bHuman Genotyping Unit-CeGen, Human Cancer Genetics Programme, Spanish National Cancer Research Center cSan Carlos University Hospital dInstitute for Health Research, University Hospital Gregorio Marañón, Madrid eUniversity Hospital Virgen de la Victoria, Malaga, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/FPC.0000000000000037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076106PMC
May 2014

Endocrine disruptors, gene deregulation and male germ cell tumors.

Int J Dev Biol 2013 ;57(2-4):225-39

Department of Cellular and Molecular Biology. Centro de Investigaciones Biológicas (CSIC), Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1387/ijdb.130042jdDOI Listing
January 2014

Differential toxicity biomarkers for irinotecan- and oxaliplatin-containing chemotherapy in colorectal cancer.

Cancer Chemother Pharmacol 2013 Jun 31;71(6):1463-72. Epub 2013 Mar 31.

Servicio de Farmacia, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, Doctor Esquerdo 46, 28007 Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00280-013-2145-6DOI Listing
June 2013

Ammonia induces aquaporin-4 rearrangement in the plasma membrane of cultured astrocytes.

Neurochem Int 2012 Dec 25;61(8):1314-24. Epub 2012 Sep 25.

Departamento de Biología Celular y Genética, Facultad de Biología, Universidad de Alcalá, 28871 Alcalá de Henares, Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuint.2012.09.008DOI Listing
December 2012

Pharmacogenetic markers of toxicity for chemotherapy in colorectal cancer patients.

Pharmacogenomics 2012 Jul;13(10):1173-91

Laboratory of Pharmacogenetics & Pharmacogenomics, Pharmacy Department, Hospital General Universitario Gregorio Marañón, Doctor Esquerdo 46, Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pgs.12.95DOI Listing
July 2012

The inhibition of Th17 immune response in vitro and in vivo by the carbosilane dendrimer 2G-NN16.

Biomaterials 2012 May 27;33(15):4002-9. Epub 2012 Feb 27.

Laboratorio InmunoBiología Molecular, Hospital General Universitario Gregorio Marañón, Doctor Esquerdo 46, 28007-Madrid, Spain.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01429612120018
Publisher Site
http://dx.doi.org/10.1016/j.biomaterials.2012.02.018DOI Listing
May 2012

Carbosilane dendrimer 2G-NN16 represses Tc17 differentiation in primary T CD8+ lymphocytes.

Mol Pharm 2012 Jan 16;9(1):102-10. Epub 2011 Nov 16.

Hospital General Universitario Gregorio Marañón, Doctor Esquerdo 46, 28007-Madrid, Spain.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/mp200305u
Publisher Site
http://dx.doi.org/10.1021/mp200305uDOI Listing
January 2012

The effects of different endocrine disruptors defining compound-specific alterations of gene expression profiles in the developing testis.

Reprod Toxicol 2012 Jan 5;33(1):106-15. Epub 2012 Jan 5.

Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Ramiro de Maeztu 9, 28040 Madrid, Spain.

View Article

Download full-text PDF

Source
http://ac.els-cdn.com/S0890623811005338/1-s2.0-S089062381100
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S089062381100533
Publisher Site
http://dx.doi.org/10.1016/j.reprotox.2011.12.012DOI Listing
January 2012

Selective induction of host genes by MVA-B, a candidate vaccine against HIV/AIDS.

J Virol 2010 Aug 9;84(16):8141-52. Epub 2010 Jun 9.

Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología CSIC, Campus Universidad Autónoma, E-28049 Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.00749-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916545PMC
August 2010

Gene-expression profiling in pancreatic cancer.

Expert Rev Mol Diagn 2010 Jul;10(5):591-601

Spanish National Cancer Research Centre, GastroIntestinal Cancer Clinical Research Unit, Clinical Research Programme, Melchor Fernandez Almagro 3, Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/erm.10.43DOI Listing
July 2010

Changes in gene expression pattern of human primary macrophages induced by carbosilane dendrimer 2G-NN16.

Pharm Res 2009 Mar 25;26(3):577-86. Epub 2008 Nov 25.

Laboratory of Pharmacogenetics and Pharmacogenomics, Hospital General Universitario Gregorio Marañon, 28007, Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11095-008-9776-zDOI Listing
March 2009

Molecular characterization of spontaneous mesenchymal stem cell transformation.

PLoS One 2008 Jan 2;3(1):e1398. Epub 2008 Jan 2.

Department of Immunology and Oncology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Universidad Autónoma de Madrid, Madrid, Spain.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0001398PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151133PMC
January 2008

Genomic profiling of circulating plasma RNA for the analysis of cancer.

Clin Chem 2007 Oct 23;53(10):1860-3. Epub 2007 Aug 23.

Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1373/clinchem.2007.089201DOI Listing
October 2007

Cascade of transcriptional induction and repression during IL-2 deprivation-induced apoptosis.

Immunol Lett 2007 Sep 24;112(1):9-29. Epub 2007 Jul 24.

Immunologie Cellulaire et Tissulaire, INSERM U543, 83 Bd de l'Hôpital, 75013 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.imlet.2007.06.004DOI Listing
September 2007

Distinct gene expression profiling after infection of immature human monocyte-derived dendritic cells by the attenuated poxvirus vectors MVA and NYVAC.

J Virol 2007 Aug 30;81(16):8707-21. Epub 2007 May 30.

Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Campus Universidad Autónoma, E-28049 Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.00444-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1951336PMC
August 2007

Human gene profiling in response to the active protein kinase, interferon-induced serine/threonine protein kinase (PKR), in infected cells. Involvement of the transcription factor ATF-3 IN PKR-induced apoptosis.

J Biol Chem 2006 Jul 13;281(27):18734-45. Epub 2006 Apr 13.

Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Ciudad Universitaria de Cantoblanco, E-28049 Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M511983200DOI Listing
July 2006

Host response to the attenuated poxvirus vector NYVAC: upregulation of apoptotic genes and NF-kappaB-responsive genes in infected HeLa cells.

J Virol 2006 Jan;80(2):985-98

Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología/CSIC, Ciudad Universitaria Cantoblanco, 28049 Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.80.2.985-998.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1346868PMC
January 2006

[Professional practice and gender in primary care].

Gac Sanit 2004 May;18 Suppl 1:112-7

Técnica de Salud, Unidad Docente de Medicina de Familia y Comunitaria de Granada, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1157/13062259DOI Listing
May 2004

Cellular gene expression survey of vaccinia virus infection of human HeLa cells.

J Virol 2003 Jun;77(11):6493-506

Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Campus Universidad Autónoma, 28049 Madrid, Spain.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC154985PMC
http://dx.doi.org/10.1128/jvi.77.11.6493-6506.2003DOI Listing
June 2003

Developmental regulation of expression of Ran/M1 and Ran/M2 isoforms of Ran-GTPase in mouse testis.

Int J Dev Biol 2003 May;47(4):307-10

Department of Cell and Developmental Biology, Centro de Investigaciones Biológicas, Madrid, Spain.

View Article

Download full-text PDF

Source
May 2003

Ran GTPase expression during early development of the mouse embryo.

Mech Dev 2002 Apr;113(1):103-6

Department of Cell and Developmental Biology, Centro de Investigaciones Biológicas, Velázquez 144, 28006 Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0925-4773(02)00007-2DOI Listing
April 2002