Lore Becker

Lore Becker

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Lore Becker

Lore Becker

Publications by authors named "Lore Becker"

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In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria.

Biochim Biophys Acta Mol Basis Dis 2020 Mar 23;1866(3):165622. Epub 2019 Nov 23.

Division of Metabolism and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland; radiz - Rare Disease Initiative Zurich, Clinical Research Priority Program for Rare Diseases, University of Zurich, Zurich, Switzerland; Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2019.165622DOI Listing
March 2020

CRN2 binds to TIMP4 and MMP14 and promotes perivascular invasion of glioblastoma cells.

Eur J Cell Biol 2019 Dec 11;98(5-8):151046. Epub 2019 Oct 11.

Centre for Biochemistry, Institute of Biochemistry I, Medical Faculty, University of Cologne, 50931, Cologne, Germany; Institute of Neuropathology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, 91054, Erlangen, Germany; Center for Physiology and Pathophysiology, Institute of Vegetative Physiology, Medical Faculty, University of Cologne, 50931, Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejcb.2019.151046DOI Listing
December 2019

Genes Whose Gain or Loss-of-Function Increases Endurance Performance in Mice: A Systematic Literature Review.

Front Physiol 2019 22;10:262. Epub 2019 Mar 22.

Exercise Biology Group, Department of Sport and Health Sciences, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.3389/fphys.2019.00262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439621PMC
March 2019

Measuring and Interpreting Oxygen Consumption Rates in Whole Fly Head Segments.

J Vis Exp 2019 01 7(143). Epub 2019 Jan 7.

Laboratory for Metabolism and Epigenetics in Aging, Leibniz Institute for Farm Animal Biology (FBN); Laboratory for Metabolism and Epigenetics in Brain Aging, Institute of Neuroregeneration & Neurorehabilitation of Qingdao University; Molecular Biology Division, Biomedical Center, Faculty of Medicine, Ludwig-Maximilians University of Munich;

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http://dx.doi.org/10.3791/58601DOI Listing
January 2019

Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.

Behav Brain Res 2018 10 29;352:187-196. Epub 2017 Sep 29.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter-Landstr. 1, 85764 Neuherberg, Germany; German Center for Diabetes Research (DZD), Ingolstädter-Landstr. 1, 85764 Neuherberg, Germany; Chair of Experimental Genetics, School of Life Science Weihenstephan, Technische Universität München, Alte Akademie 8, 85354 Freising, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2017.09.048DOI Listing
October 2018

Genes Whose Gain or Loss-Of-Function Increases Skeletal Muscle Mass in Mice: A Systematic Literature Review.

Front Physiol 2018 22;9:553. Epub 2018 May 22.

Exercise Biology Group, Faculty of Sport and Health Sciences, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.3389/fphys.2018.00553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992403PMC
May 2018

Analysis of locomotor behavior in the German Mouse Clinic.

J Neurosci Methods 2018 04 5;300:77-91. Epub 2017 May 5.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, Ingolstaedter Landstr. 1, 85764 Neuherberg, Germany; Institute of Developmental Genetics, Helmholtz Zentrum München, Ingolstaedter Landstr.1, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1016/j.jneumeth.2017.05.005DOI Listing
April 2018

Rapid and transient oxygen consumption increase following acute HDAC/KDAC inhibition in Drosophila tissue.

Sci Rep 2018 03 8;8(1):4199. Epub 2018 Mar 8.

Munich Center of Integrated Protein Science and Biomedical Center, Ludwig-Maximilians University of Munich, Planegg-Martinsried, 80336, Germany.

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http://dx.doi.org/10.1038/s41598-018-22674-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843646PMC
March 2018

Interplay between H1 and HMGN epigenetically regulates OLIG1&2 expression and oligodendrocyte differentiation.

Nucleic Acids Res 2017 04;45(6):3031-3045

Protein Section, Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/nar/gkw1222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389484PMC
April 2017

Life span extension by targeting a link between metabolism and histone acetylation in Drosophila.

EMBO Rep 2016 Mar 18;17(3):455-69. Epub 2016 Jan 18.

Department of Physiological Chemistry, Biomedical Center and Center for Integrated Protein Science Munich, Ludwig-Maximilians University, Planegg-Martinsried, Germany Munich Cluster for Systems Neurology (SyNergy), Munich, Germany

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http://dx.doi.org/10.15252/embr.201541132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772992PMC
March 2016

Overexpression of the mitochondrial methyltransferase TFB1M in the mouse does not impact mitoribosomal methylation status or hearing.

Hum Mol Genet 2015 Dec 12;24(25):7286-94. Epub 2015 Oct 12.

Department of Laboratory Medicine, Karolinska Institutet, Retzius väg 8, 171 77 Stockholm, Sweden, Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Strasse 9b, 50931 Cologne, Germany

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http://dx.doi.org/10.1093/hmg/ddv427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664167PMC
December 2015

MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy.

PLoS One 2014 15;9(12):e114918. Epub 2014 Dec 15.

Department of Neurology, Friedrich-Baur-Institute, Ludwig-Maximilians-University, Munich, Germany; German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environment and Health, Neuherberg, Germany; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany; German Center for Vertigo and Balance Disorders, Munich, Germany; German Network for Mitochondrial Disorders (mitoNET), Munich, Germany.

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http://pubman.mpdl.mpg.de/pubman/item/escidoc:2147508:2/comp
Web Search
http://dx.plos.org/10.1371/journal.pone.0114918
Publisher Site
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0114918PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266617PMC
November 2015

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.

Authors:
Martin Hrabě de Angelis George Nicholson Mohammed Selloum Jacqui White Hugh Morgan Ramiro Ramirez-Solis Tania Sorg Sara Wells Helmut Fuchs Martin Fray David J Adams Niels C Adams Thure Adler Antonio Aguilar-Pimentel Dalila Ali-Hadji Gregory Amann Philippe André Sarah Atkins Aurelie Auburtin Abdel Ayadi Julien Becker Lore Becker Elodie Bedu Raffi Bekeredjian Marie-Christine Birling Andrew Blake Joanna Bottomley Mike Bowl Véronique Brault Dirk H Busch James N Bussell Julia Calzada-Wack Heather Cater Marie-France Champy Philippe Charles Claire Chevalier Francesco Chiani Gemma F Codner Roy Combe Roger Cox Emilie Dalloneau André Dierich Armida Di Fenza Brendan Doe Arnaud Duchon Oliver Eickelberg Chris T Esapa Lahcen El Fertak Tanja Feigel Irina Emelyanova Jeanne Estabel Jack Favor Ann Flenniken Alessia Gambadoro Lilian Garrett Hilary Gates Anna-Karin Gerdin George Gkoutos Simon Greenaway Lisa Glasl Patrice Goetz Isabelle Goncalves Da Cruz Alexander Götz Jochen Graw Alain Guimond Wolfgang Hans Geoff Hicks Sabine M Hölter Heinz Höfler John M Hancock Robert Hoehndorf Tertius Hough Richard Houghton Anja Hurt Boris Ivandic Hughes Jacobs Sylvie Jacquot Nora Jones Natasha A Karp Hugo A Katus Sharon Kitchen Tanja Klein-Rodewald Martin Klingenspor Thomas Klopstock Valerie Lalanne Sophie Leblanc Christoph Lengger Elise le Marchand Tonia Ludwig Aline Lux Colin McKerlie Holger Maier Jean-Louis Mandel Susan Marschall Manuel Mark David G Melvin Hamid Meziane Kateryna Micklich Christophe Mittelhauser Laurent Monassier David Moulaert Stéphanie Muller Beatrix Naton Frauke Neff Patrick M Nolan Lauryl Mj Nutter Markus Ollert Guillaume Pavlovic Natalia S Pellegata Emilie Peter Benoit Petit-Demoulière Amanda Pickard Christine Podrini Paul Potter Laurent Pouilly Oliver Puk David Richardson Stephane Rousseau Leticia Quintanilla-Fend Mohamed M Quwailid Ildiko Racz Birgit Rathkolb Fabrice Riet Janet Rossant Michel Roux Jan Rozman Ed Ryder Jennifer Salisbury Luis Santos Karl-Heinz Schäble Evelyn Schiller Anja Schrewe Holger Schulz Ralf Steinkamp Michelle Simon Michelle Stewart Claudia Stöger Tobias Stöger Minxuan Sun David Sunter Lydia Teboul Isabelle Tilly Glauco P Tocchini-Valentini Monica Tost Irina Treise Laurent Vasseur Emilie Velot Daniela Vogt-Weisenhorn Christelle Wagner Alison Walling Bruno Weber Olivia Wendling Henrik Westerberg Monja Willershäuser Eckhard Wolf Anne Wolter Joe Wood Wolfgang Wurst Ali Önder Yildirim Ramona Zeh Andreas Zimmer Annemarie Zimprich Chris Holmes Karen P Steel Yann Herault Valérie Gailus-Durner Ann-Marie Mallon Steve Dm Brown

Nat Genet 2015 Sep 27;47(9):969-978. Epub 2015 Jul 27.

MRC Harwell, Medical Research Council, Harwell, UK.

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http://dx.doi.org/10.1038/ng.3360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564951PMC
September 2015

MiR-34a deficiency accelerates medulloblastoma formation in vivo.

Int J Cancer 2015 May 25;136(10):2293-303. Epub 2014 Nov 25.

Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Hufelandstr. 55 45147, Essen, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany; German Cancer Research Center (DKFZ), D-69120, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.29294DOI Listing
May 2015

Genetic evidence for the adhesion protein IgSF9/Dasm1 to regulate inhibitory synapse development independent of its intracellular domain.

J Neurosci 2014 Mar;34(12):4187-99

Department of Molecules-Signaling-Development and Synaptic Receptor Trafficking Group, Max Planck Institute of Neurobiology, D-82152 Martinsried, Germany, German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environment and Health, D-85764 Neuherberg, Germany, Department of Neurology, Friedrich-Baur-Institute, Ludwig-Maximilians-University, D-80336 Munich, Germany, Munich Cluster for Systems Neurology (SyNergy), D-80336 Munich, Germany, and Department of Physiology II, University of Bonn, D-53115 Bonn, Germany.

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http://dx.doi.org/10.1523/JNEUROSCI.3671-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608096PMC
March 2014

Innovations in phenotyping of mouse models in the German Mouse Clinic.

Mamm Genome 2012 Oct 29;23(9-10):611-22. Epub 2012 Aug 29.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstrasse 1, 85764 Neuherberg/Munich, Germany.

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http://dx.doi.org/10.1007/s00335-012-9415-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463795PMC
October 2012

"Sighted C3H" mice--a tool for analysing the influence of vision on mouse behaviour?

Front Biosci 2008 May 1;13:5810-23. Epub 2008 May 1.

Institute of Developmental Genetics, Helmholtz Center Munich-German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany.

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http://dx.doi.org/10.2741/3118DOI Listing
May 2008

The mouse Trm1-like gene is expressed in neural tissues and plays a role in motor coordination and exploratory behaviour.

Gene 2007 Mar 17;389(2):174-85. Epub 2006 Nov 17.

Department of Cell and Molecular Biology, Institute of Biochemistry and Biotechnology, Technical University of Braunschweig, Spielmannstrasse 7, 38106 Braunschweig, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S037811190600705
Publisher Site
http://dx.doi.org/10.1016/j.gene.2006.11.004DOI Listing
March 2007