Linda T Vahdat

Linda T Vahdat

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Linda T Vahdat

Linda T Vahdat

Publications by authors named "Linda T Vahdat"

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59Publications

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Sacituzumab Govitecan-hziy in Refractory Metastatic Triple-Negative Breast Cancer.

N Engl J Med 2019 02;380(8):741-751

From the Massachusetts General Hospital Cancer Center (A.B., S.J.I.) and Dana-Farber Cancer Institute (S.M.T.), Harvard Medical School, Boston; Vanderbilt-Ingram Cancer Center, Nashville (I.A.M., V.G.A.); Weill Cornell Medical College (L.T.V.) and New York-Presbyterian-Columbia University Irving Medical Center (K.K.), New York; University of Colorado Cancer Center, Aurora (J.R.D.); Texas Oncology, Baylor University Medical Center, US Oncology, Dallas (J.O.); Orlando Health University of Florida Health Cancer Center, Orlando (R.L.M., N.C.S.); Yale University School of Medicine, New Haven, CT (A.D.S.); University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco (H.S.R.); Immunomedics, Morris Plains, NJ (D.M.G., R.I., S.W., R.M.S., W.A.W.); and AIS Consulting, Ann Arbor, MI (A.M.S.).

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http://www.nejm.org/doi/10.1056/NEJMoa1814213
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http://dx.doi.org/10.1056/NEJMoa1814213DOI Listing
February 2019

Sacituzumab govitecan: an antibody-drug conjugate.

Expert Opin Biol Ther 2017 08 22;17(8):1027-1031. Epub 2017 May 22.

a Department of Medicine , Weill Cornell Medicine , New York , NY , USA.

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http://dx.doi.org/10.1080/14712598.2017.1331214DOI Listing
August 2017

An Integrated Systems Biology Approach Identifies TRIM25 as a Key Determinant of Breast Cancer Metastasis.

Cell Rep 2017 08;20(7):1623-1640

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Cellular and Developmental Biology, Weill Cornell Medical College, New York, NY, USA; Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.07.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985663PMC
August 2017

Efficacy and Safety of Anti-Trop-2 Antibody Drug Conjugate Sacituzumab Govitecan (IMMU-132) in Heavily Pretreated Patients With Metastatic Triple-Negative Breast Cancer.

J Clin Oncol 2017 Jul 14;35(19):2141-2148. Epub 2017 Mar 14.

Aditya Bardia, Steven J. Isakoff, and Dejan Juric, Massachusetts General Hospital Cancer Center; Aditya Bardia, Steven J. Isakoff, Dejan Juric, and Sara M. Tolaney, Harvard Medical School; Sara M. Tolaney, Dana-Farber Cancer Institute, Boston, MA; Ingrid A. Mayer, Vandana Abramson, and Jordan Berlin, Vanderbilt-Ingram Cancer Center, Nashville, TN; Jennifer R. Diamond and Wells A. Messersmith, University of Colorado Cancer Center, Aurora, CO; Rebecca L. Moroose and Nikita C. Shah, University of Florida Health Cancer Center, Orlando, FL; Alexander N. Starodub, Indiana University Health Center for Cancer Care, Goshen, IN; Joyce O'Shaughnessy, Texas Oncology-Baylor Charles A. Sammons Cancer Center; Joyce O'Shaughnessy, US Oncology, Dallas, TX; Kevin Kalinsky, Columbia University Herbert Irving Comprehensive Cancer Center; Allyson J. Ocean and Linda T. Vahdat, Weill Cornell Medicine, New York, NY; Michael Guarino, Helen F. Graham Cancer Center, Newark, DE; William A. Wegener, Pius Maliakal, Robert M. Sharkey, Serengulam V. Govindan, and David M. Goldenberg, Immunomedics, Morris Plains, NJ.

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http://dx.doi.org/10.1200/JCO.2016.70.8297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559902PMC
July 2017

Glutamine for the treatment of vincristine-induced neuropathy in children and adolescents with cancer.

Support Care Cancer 2017 03 9;25(3):701-708. Epub 2016 Nov 9.

Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Columbia University Medical Center, 161 Fort Washington Avenue, New York, NY, 10032, USA.

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http://dx.doi.org/10.1007/s00520-016-3441-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598352PMC
March 2017

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance.

Nature 2015 Nov 11;527(7579):472-6. Epub 2015 Nov 11.

Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/nature15748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662610PMC
November 2015

EMERGE: A Randomized Phase II Study of the Antibody-Drug Conjugate Glembatumumab Vedotin in Advanced Glycoprotein NMB-Expressing Breast Cancer.

J Clin Oncol 2015 May 6;33(14):1609-19. Epub 2015 Apr 6.

Denise A. Yardley, Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN; Robert Weaver, Florida Cancer Specialists, Tampa, FL; Michelle E. Melisko, University of California, San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco; Scott Cruickshank, Scott Cruickshank & Associates, Santa Barbara; Agustin A. Garcia, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, CA; Mansoor N. Saleh, Georgia Cancer Specialists, Sandy Springs, GA; Francis P. Arena, New York University Langons Arena Oncology, Lake Success; Tessa Cigler and Linda T. Vahdat, Weill Cornell Medical College, New York, NY; Andres Forero, University of Alabama, Birmingham, AL; Alison Stopeck, University of Arizona Cancer Center, Tucson, AZ; Dennis Citrin, Cancer Treatment Centers of America/Midwestern Regional Medical Center, Zion; Ira Oliff, Orchard Healthcare Research, Skokie, IL; Rebecca Bechhold, Oncology Hematology Care, Cincinnati, OH; Randa Loutfi, Henry Ford Health System, Detroit, MI; and Elizabeth Crowley, Jennifer Green, Thomas Hawthorne, Michael J. Yellin, and Thomas A. Davis, Celldex Therapeutics, Hampton, NJ.

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http://dx.doi.org/10.1200/JCO.2014.56.2959DOI Listing
May 2015

Remodeling of the methylation landscape in breast cancer metastasis.

PLoS One 2014 1;9(8):e103896. Epub 2014 Aug 1.

Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America; Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0103896PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118917PMC
April 2015

Novel data in metastatic breast cancer.

Authors:
Linda T Vahdat

Clin Adv Hematol Oncol 2013 ;11(10 Suppl 16):13-5

Weill Cornell Medical College, New York, New York.

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November 2014

New developments in metastatic breast cancer: general discussion.

Clin Adv Hematol Oncol 2013 ;11(10 Suppl 16):16-7

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November 2014

New developments in metastatic breast cancer: integrating recent data into clinical practice.

Clin Adv Hematol Oncol 2013 ;11(10 Suppl 16):1-18; quiz 19

University of California San Francisco, San Francisco, California.

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November 2014

Eribulin monotherapy in patients aged 70 years and older with metastatic breast cancer.

Oncologist 2014 Apr 28;19(4):318-27. Epub 2014 Mar 28.

University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, USA; Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology, Barcelona, Spain; Weill Cornell Medical College, New York, New York, USA; Jules Bordet Institute, Brussels, Belgium; University of Leeds and St James's Institute of Oncology, Leeds, UK; Formerly of Eisai Ltd, Hatfield, UK; Eisai Inc., Woodcliff Lake, New Jersey, USA; NJS Associates Company, Somerset, New Jersey USA; Baylor-Charles A. Sammons Cancer Center, Texas Oncology, and US Oncology, Dallas, Texas, USA.

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http://theoncologist.alphamedpress.org/cgi/doi/10.1634/theon
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http://dx.doi.org/10.1634/theoncologist.2013-0282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983814PMC
April 2014

BreastPRS is a gene expression assay that stratifies intermediate-risk Oncotype DX patients into high- or low-risk for disease recurrence.

Breast Cancer Res Treat 2013 Jun 18;139(3):705-15. Epub 2013 Jun 18.

Department of Pathology and Laboratory Medicine, New York-Presbyterian Hospital, Weill Cornell Medical College, 525 East 68th Street, Starr 1031E, New York, NY 10065, USA.

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http://dx.doi.org/10.1007/s10549-013-2604-0DOI Listing
June 2013

Suppression of miRNA-708 by polycomb group promotes metastases by calcium-induced cell migration.

Cancer Cell 2013 Jan;23(1):63-76

Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.ccr.2012.11.019DOI Listing
January 2013

Microenvironmental regulation of epithelial-mesenchymal transitions in cancer.

Cancer Res 2012 Oct 20;72(19):4883-9. Epub 2012 Sep 20.

Department of Cardiothoracic Surgery, Neuberger Berman Lung Cancer Research Center, Weill Cornell Medical College of Cornell University, New York, New York10065, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649848PMC
October 2012

Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition.

Cancer Res 2012 Mar 26;72(6):1384-94. Epub 2012 Jan 26.

Department of Cardiothoracic Surgery and Neuberger Berman Lung Cancer Center, Weill Cornell Medical College of Cornell University, New York, New York, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-2905DOI Listing
March 2012

The use of an antibody drug conjugate, glembatumumab vedotin (CDX-011), for the treatment of breast cancer.

Expert Opin Biol Ther 2012 Feb 9;12(2):259-63. Epub 2012 Jan 9.

Weill Cornell Medical College, Division of Hematology and Oncology, Department of Medicine, 425 East 61st Street, 8th floor, NY 10065, USA.

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http://dx.doi.org/10.1517/14712598.2012.642357DOI Listing
February 2012

Eribulin mesylate.

Clin Cancer Res 2011 Nov 22;17(21):6615-22. Epub 2011 Aug 22.

Department of Medicine, Division of Hematology and Oncology, Weill Cornell Medical College, New York, New York 10065, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-1807DOI Listing
November 2011

Novel treatment options in the management of metastatic breast cancer.

Clin Adv Hematol Oncol 2011 May;9(5 Suppl 10):1-16

Clinical Cancer Research Groups, Leeds Institute of Molecular Medicine and St James's Institute of Oncology, Leeds, England.

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May 2011

Phase II study evaluating the efficacy and safety of sagopilone (ZK-EPO) in patients with metastatic breast cancer that has progressed following chemotherapy.

Breast Cancer Res Treat 2010 Oct 10;123(3):837-42. Epub 2010 Aug 10.

Department of Breast Medical Oncology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe, Box 1354, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s10549-010-1102-xDOI Listing
October 2010

Eribulin mesylate for the treatment of breast cancer.

Expert Opin Pharmacother 2010 Jun;11(9):1587-93

Division of Hematology and Medical Oncology, Weill Medical College of Cornell University, 425 East 61st Street - 8th Floor, New York, NY 10021, USA.

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http://dx.doi.org/10.1517/14656566.2010.486790DOI Listing
June 2010

The effect of a contemplative self-healing program on quality of life in women with breast and gynecologic cancers.

Altern Ther Health Med 2010 May-Jun;16(3):30-7

Center for Complementary and Integrative Medicine, Weill Cornell Medical College, New York, New York, USA.

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June 2010

Phase III trials of eribulin mesylate (E7389) in extensively pretreated patients with locally recurrent or metastatic breast cancer.

Clin Breast Cancer 2010 Apr;10(2):160-3

Leeds Institute of Molecular Medicine, St. James University Hospital, Leeds, United Kingdom.

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http://dx.doi.org/10.3816/CBC.2010.n.023DOI Listing
April 2010

Novel combinations for the treatment of metastatic breast cancer.

Authors:
Linda T Vahdat

Cancers (Basel) 2010 Jan 14;2(1):1-19. Epub 2010 Jan 14.

Weill Cornell Medical College, 425 East 61st Street, 8th Floor, New York, NY 10065, USA.

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http://dx.doi.org/10.3390/cancers2010001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827587PMC
January 2010

Clinical studies with epothilones for the treatment of metastatic breast cancer.

Authors:
Linda T Vahdat

Semin Oncol 2008 Apr;35(2 Suppl 2):S22-30; quiz S40

Division of Hematology/Oncology, Weill Medical College of Cornell University, New York, NY 20021.

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http://dx.doi.org/10.1053/j.seminoncol.2008.02.003DOI Listing
April 2008

Epothilones: clinical update and future directions.

Oncology (Williston Park) 2008 Apr;22(4):408-16; discussion 416, 421, 424 passim

Weill Cornell Breast Center, Cornell University/ New York-Presbyterian Hospital, New York, NY 10021, USA.

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April 2008

Circulating endothelial progenitor cells correlate to stage in patients with invasive breast cancer.

Breast Cancer Res Treat 2008 Jan 15;107(1):133-8. Epub 2007 Feb 15.

Department of Medicine, Division of Hematology/Oncology, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY 10021, USA.

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http://link.springer.com/content/pdf/10.1007/s10549-007-9519
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http://link.springer.com/10.1007/s10549-007-9519-6
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http://dx.doi.org/10.1007/s10549-007-9519-6DOI Listing
January 2008

Chemotherapy-induced peripheral neuropathy: pathogenesis and emerging therapies.

Support Care Cancer 2004 Sep;12(9):619-25

Division of Hematology/Medical Oncology, Weill Medical College of Cornell University, New York, NY, USA.

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http://dx.doi.org/10.1007/s00520-004-0657-7DOI Listing
September 2004

Chemotherapy-induced palmar-plantar erythrodysesthesia syndrome: etiology and emerging therapies.

Support Cancer Ther 2004 Jul;1(4):213-8

Division of Hematology/Medical Oncology, Weill Medical College of Cornell University, New York.

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http://dx.doi.org/10.3816/SCT.2004.n.013DOI Listing
July 2004