Publications by authors named "Liangsu Wang"

32Publications

ablation prevents Western diet-induced weight gain and hepatic steatosis because of impaired fat absorption.

Am J Physiol Endocrinol Metab 2017 08 4;313(2):E121-E133. Epub 2017 Apr 4.

Department of Pathology and Cell Biology, Columbia University, New York, New York;

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August 2017

Increased Bile Acid Synthesis and Impaired Bile Acid Transport in Human Obesity.

J Clin Endocrinol Metab 2016 05 18;101(5):1935-44. Epub 2015 Dec 18.

Department of Pathology and Cell Biology (R.A.H.), Columbia University, New York, New York 10032; Department of Clinical and Experimental Medicine (S.C., M.N., B.A., E.F.), University of Pisa School of Medicine, 56100 Pisa, Italy; Merck Research Laboratories (J.C.-P., D.X., L.W., M.C.), Cardiometabolic Disease, Kenilworth, New Jersey 07033; and CNR Institute of Clinical Physiology (E.F.), 56100 Pisa, Italy.

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May 2016

Gene expression in WAT from healthy humans and monkeys correlates with FGF21-induced browning of WAT in mice.

Obesity (Silver Spring) 2015 Sep;23(9):1818-29

Department of Genetics and Pharmacogenomics, Early Development and Discovery Sciences, Merck Research Laboratories, Merck Sharp & Dohme Corp., Kenilworth, New Jersey, USA.

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September 2015

Improved Stability of Proline-Derived Direct Thrombin Inhibitors through Hydroxyl to Heterocycle Replacement.

ACS Med Chem Lett 2015 May 13;6(5):553-7. Epub 2015 Mar 13.

Departments of Medicinal Chemistry, Process Chemistry, Drug Metabolism and Pharmacokinetics, Preclinical Development, Pharmacology, and Thrombosis, Merck Research Laboratories , Kenilworth, New Jersey 07033, United States.

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May 2015

Potentiation of insulin-mediated glucose lowering without elevated hypoglycemia risk by a small molecule insulin receptor modulator.

PLoS One 2015 23;10(3):e0122012. Epub 2015 Mar 23.

Early Development and Discovery Sciences, Merck Research Laboratories, Merck Sharp & Dohme Corp., Whitehouse Station, NJ 08889, United States of America.

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February 2016

Racing to define pharmaceutical R&D external innovation models.

Drug Discov Today 2015 Mar 30;20(3):361-70. Epub 2014 Oct 30.

The Boston Consulting Group, Exchange Place, Boston, MA 02109, USA.

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March 2015

Identification of four novel genes contributing to familial elevated plasma HDL cholesterol in humans.

J Lipid Res 2014 Aug 2;55(8):1693-701. Epub 2014 Jun 2.

A*STAR Institute and Yong Loo Lin School of Medicine, National University of Singapore, Singapore Centre for Molecular Medicine and Therapeutics, and Child and Family Research Institute, University of British Columbia, Vancouver, BC, Canada.

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August 2014

Development of an integrated semi-automated system for in vitro pharmacodynamic modelling.

J Antimicrob Chemother 2008 Nov 21;62(5):1070-7. Epub 2008 Jul 21.

Department of Infectious Disease Research, Merck Research Laboratories, 126 E. Lincoln Avenue, Rahway, NJ 07065, USA.

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November 2008

Control and prevention of MRSA infections.

Methods Mol Biol 2007 ;391:209-25

Infectious Disease Research, Merck & Co Inc, Rahway, NJ, USA.

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January 2008

Pharmacoeconomics of treatment with the newer anti-Gram-positive agents.

Expert Opin Pharmacother 2006 May;7(7):885-97

Department of Infectious Diseases, Merck Research Laboratories, Rahway, NJ 07065, USA.

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May 2006

Genome-wide operon prediction in Staphylococcus aureus.

Nucleic Acids Res 2004 13;32(12):3689-702. Epub 2004 Jul 13.

Elitra Pharmaceuticals Inc., 10410 Science Center Drive, San Diego, CA 92121, USA.

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July 2004