Liang Tong

Liang Tong

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Biophysical characterizations of the recognition of the AAUAAA polyadenylation signal.

RNA 2019 Aug 28. Epub 2019 Aug 28.

Columbia University

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http://dx.doi.org/10.1261/rna.070870.119DOI Listing
August 2019

MiR-373 exacerbates renal injury and fibrosis via NF-κB/MatrixMetalloproteinase-9 signaling by targeting Sirtuin1.

Genomics 2019 07 1;111(4):786-792. Epub 2018 May 1.

Department of Nephrology, The Third Xiangya Hospital of Central South University, Changsha 410013, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08887543183026
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http://dx.doi.org/10.1016/j.ygeno.2018.04.017DOI Listing
July 2019

Identification of Three Sequence Motifs in the Transcription Termination Factor Sen1 that Mediate Direct Interactions with Nrd1.

Structure 2019 Jul 16;27(7):1156-1161.e4. Epub 2019 May 16.

Department of Biological Sciences, Columbia University, New York, NY 10027, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2019.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610696PMC
July 2019

Structural and mechanistic basis of mammalian Nudt12 RNA deNADding.

Nat Chem Biol 2019 06 17;15(6):575-582. Epub 2019 May 17.

Department Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ, USA.

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http://www.nature.com/articles/s41589-019-0293-7
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http://dx.doi.org/10.1038/s41589-019-0293-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527130PMC
June 2019

Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription.

Cell Chem Biol 2019 May 14;26(5):711-723.e14. Epub 2019 Mar 14.

David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; MIT Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2019.02.009DOI Listing
May 2019

Elastic Higher-Order Topological Insulator with Topologically Protected Corner States.

Phys Rev Lett 2019 May;122(20):204301

State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body, Hunan University, Changsha, Hunan 410082, People's Republic of China.

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http://dx.doi.org/10.1103/PhysRevLett.122.204301DOI Listing
May 2019

Good Performance and Flexible PEDOT:PSS/CuSe Nanowire Thermoelectric Composite Films.

ACS Appl Mater Interfaces 2019 Apr 22;11(13):12819-12829. Epub 2019 Mar 22.

State Key Laboratory of High Performance Ceramics and Superfine Microstructure , Shanghai Institute of Ceramics, Chinese Academy of Science , Shanghai 200050 , China.

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http://dx.doi.org/10.1021/acsami.9b01718DOI Listing
April 2019

An allosteric mechanism for potent inhibition of human ATP-citrate lyase.

Nature 2019 Apr 3;568(7753):566-570. Epub 2019 Apr 3.

Department of Biological Sciences, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.1038/s41586-019-1094-6DOI Listing
April 2019

Signal transduction mediated by the plant UV-B photoreceptor UVR8.

New Phytol 2019 02 13;221(3):1247-1252. Epub 2018 Oct 13.

National Key Laboratory of Plant Molecular Genetics (NKLPMG), CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology (SIPPE), Chinese Academy of Sciences, Shanghai, 200032, China.

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http://dx.doi.org/10.1111/nph.15469DOI Listing
February 2019

High-resolution structures of inhibitor complexes of human indoleamine 2,3-dioxygenase 1 in a new crystal form.

Acta Crystallogr F Struct Biol Commun 2018 Nov 17;74(Pt 11):717-724. Epub 2018 Oct 17.

Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

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http://scripts.iucr.org/cgi-bin/paper?S2053230X18012955
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http://dx.doi.org/10.1107/S2053230X18012955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213978PMC
November 2018

Quercetin‑3‑methyl ether suppresses human breast cancer stem cell formation by inhibiting the Notch1 and PI3K/Akt signaling pathways.

Int J Mol Med 2018 Sep 25;42(3):1625-1636. Epub 2018 Jun 25.

Dongguan Key Laboratory of Medical Bioactive Molecular Developmental and Translational Research, Guangdong Medical University, Dongguan, Guangdong 523808, P.R. China.

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http://dx.doi.org/10.3892/ijmm.2018.3741DOI Listing
September 2018

Molecular mechanism for the inhibition of DXO by adenosine 3',5'-bisphosphate.

Biochem Biophys Res Commun 2018 09 1;504(1):89-95. Epub 2018 Sep 1.

Department of Biology Education, Kyungpook National University, Daegu 41566, South Korea; Department of Biological Sciences, Columbia University, New York, NY 10027, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.08.135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145842PMC
September 2018

How Does Polymerization Regulate Human Acetyl-CoA Carboxylase 1?

Authors:
Jia Wei Liang Tong

Biochemistry 2018 09 13;57(38):5495-5496. Epub 2018 Sep 13.

Department of Biological Sciences , Columbia University , New York , New York 10027 , United States.

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http://dx.doi.org/10.1021/acs.biochem.8b00881DOI Listing
September 2018

An efficient Bayesian kinetic lumping algorithm to identify metastable conformational states via Gibbs sampling.

J Chem Phys 2018 Aug;149(7):072337

HKUST-Shenzhen Research Institute, Hi-Tech Park, Nanshan, Shenzhen 518057, China.

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http://dx.doi.org/10.1063/1.5027001DOI Listing
August 2018

Insulin Hexamer-Caged Gadolinium Ion as MRI Contrast-o-phore.

Chemistry 2018 Jul 4;24(42):10646-10652. Epub 2018 Jul 4.

Departments of Medicine, Biomedical Engineering and Systems Biology, Columbia University, 630 W. 168th St., Box 84, New York, NY, 10032, USA.

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http://doi.wiley.com/10.1002/chem.201801388
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http://dx.doi.org/10.1002/chem.201801388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347121PMC
July 2018

Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia.

Cancer Cell 2018 07;34(1):136-147.e6

Institute for Cancer Genetics, Columbia University, New York, NY 10032, USA; Department of Systems Biology, Columbia University, New York, NY 10032, USA; Department of Pediatrics, Columbia University Medical Center, 1130 St. Nicholas Avenue, ICRC 402, New York, NY 10032, USA; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049837PMC
July 2018

Integrator subunit 4 is a 'Symplekin-like' scaffold that associates with INTS9/11 to form the Integrator cleavage module.

Nucleic Acids Res 2018 05;46(8):4241-4255

Department of Biochemistry and Molecular Biology, University of Texas Medical Branch at Galveston, Galveston, TX 77550, USA.

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http://dx.doi.org/10.1093/nar/gky100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934644PMC
May 2018

Structural biology of the separase-securin complex with crucial roles in chromosome segregation.

Curr Opin Struct Biol 2018 04 14;49:114-122. Epub 2018 Feb 14.

Department of Biological Sciences Columbia University New York, NY 10027, USA. Electronic address:

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http://dx.doi.org/10.1016/j.sbi.2018.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915870PMC
April 2018

Simultaneous estimation of QTL parameters for mapping multiple traits.

J Genet 2018 Mar;97(1):267-274

School of Mathematical Sciences, Heilongjiang University, Harbin 150080, People's Republic of China.

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March 2018

Molecular basis for the recognition of the human AAUAAA polyadenylation signal.

Proc Natl Acad Sci U S A 2018 02 5;115(7):E1419-E1428. Epub 2017 Dec 5.

Department of Biological Sciences, Columbia University, New York, NY 10027;

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http://dx.doi.org/10.1073/pnas.1718723115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816196PMC
February 2018

UVR8 interacts with WRKY36 to regulate HY5 transcription and hypocotyl elongation in Arabidopsis.

Nat Plants 2018 02 29;4(2):98-107. Epub 2018 Jan 29.

National Key Laboratory of Plant Molecular Genetics, Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China.

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http://www.nature.com/articles/s41477-017-0099-0
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http://dx.doi.org/10.1038/s41477-017-0099-0DOI Listing
February 2018

UVR8 Interacts with BES1 and BIM1 to Regulate Transcription and Photomorphogenesis in Arabidopsis.

Dev Cell 2018 02 1;44(4):512-523.e5. Epub 2018 Feb 1.

National Key Laboratory of Plant Molecular Genetics (NKLPMG), CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology (SIPPE), Chinese Academy of Sciences, 200031 Shanghai, P. R. China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15345807173107
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http://dx.doi.org/10.1016/j.devcel.2017.12.028DOI Listing
February 2018

NMR Signal Quenching from Bound Biradical Affinity Reagents in DNP Samples.

J Phys Chem B 2017 12 29;121(48):10770-10781. Epub 2017 Nov 29.

Department of Chemistry, Columbia University , New York, New York 10027, United States.

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http://dx.doi.org/10.1021/acs.jpcb.7b08274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842680PMC
December 2017

Striking Diversity in Holoenzyme Architecture and Extensive Conformational Variability in Biotin-Dependent Carboxylases.

Authors:
Liang Tong

Adv Protein Chem Struct Biol 2017 23;109:161-194. Epub 2017 May 23.

Columbia University, New York, NY, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.apcsb.2017.04.006DOI Listing
November 2017

Atlas-Based Segmentation of Temporal Bone Anatomy.

Int J Comput Assist Radiol Surg 2017 Nov 29;12(11):1937-1944. Epub 2017 Aug 29.

Department of Otolaryngology, The Ohio State University and Nationwide Children's Hospital, Columbus, OH, USA.

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http://dx.doi.org/10.1007/s11548-017-1658-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676303PMC
November 2017

Structural and functional studies of pyruvate carboxylase regulation by cyclic di-AMP in lactic acid bacteria.

Proc Natl Acad Sci U S A 2017 08 14;114(35):E7226-E7235. Epub 2017 Aug 14.

Department of Biological Sciences, Columbia University, New York, NY 10027;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1704756114
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http://dx.doi.org/10.1073/pnas.1704756114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584425PMC
August 2017

Crystal Structure of the SPOC Domain of the Arabidopsis Flowering Regulator FPA.

PLoS One 2016 11;11(8):e0160694. Epub 2016 Aug 11.

Department of Biological Sciences, Columbia University, New York, NY, 10027, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160694PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981400PMC
July 2017

Crystal structure of a Pseudomonas malonate decarboxylase holoenzyme hetero-tetramer.

Nat Commun 2017 07 31;8(1):160. Epub 2017 Jul 31.

Department of Biological Sciences, Columbia University, New York, NY, 10027, USA.

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http://dx.doi.org/10.1038/s41467-017-00233-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5534430PMC
July 2017

WASH maintains NKp46 ILC3 cells by promoting AHR expression.

Nat Commun 2017 06 7;8:15685. Epub 2017 Jun 7.

Key Laboratory of Infection and Immunity of CAS, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

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http://dx.doi.org/10.1038/ncomms15685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467242PMC
June 2017

c-di-AMP modulates Listeria monocytogenes central metabolism to regulate growth, antibiotic resistance and osmoregulation.

Mol Microbiol 2017 04 8;104(2):212-233. Epub 2017 Mar 8.

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.

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http://dx.doi.org/10.1111/mmi.13622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391996PMC
April 2017

Molecular basis for the interaction between Integrator subunits IntS9 and IntS11 and its functional importance.

Proc Natl Acad Sci U S A 2017 04 10;114(17):4394-4399. Epub 2017 Apr 10.

Department of Biological Sciences, Columbia University, New York, NY 10027;

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http://dx.doi.org/10.1073/pnas.1616605114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410846PMC
April 2017

Structural basis of dual Ca/pH regulation of the endolysosomal TRPML1 channel.

Nat Struct Mol Biol 2017 03 23;24(3):205-213. Epub 2017 Jan 23.

Department of Biological Sciences, Columbia University, New York, New York, USA.

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http://dx.doi.org/10.1038/nsmb.3362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336481PMC
March 2017

Molecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation.

Sci Rep 2017 03 3;7:43906. Epub 2017 Mar 3.

Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

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http://dx.doi.org/10.1038/srep43906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335568PMC
March 2017

5' End Nicotinamide Adenine Dinucleotide Cap in Human Cells Promotes RNA Decay through DXO-Mediated deNADding.

Cell 2017 03;168(6):1015-1027.e10

Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.02.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371429PMC
March 2017

Malignant solitary fibrous tumor in retroperitoneum: A case report and literature review.

Medicine (Baltimore) 2017 Mar;96(11):e6373

Department of Urology, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.

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http://dx.doi.org/10.1097/MD.0000000000006373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369933PMC
March 2017

Heme Oxygenase 2 Binds Myristate to Regulate Retrovirus Assembly and TLR4 Signaling.

Cell Host Microbe 2017 Feb 26;21(2):220-230. Epub 2017 Jan 26.

Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, and Department of Microbiology and Immunology, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.chom.2017.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300893PMC
February 2017

Molecular mechanism for the regulation of yeast separase by securin.

Nature 2017 02 1;542(7640):255-259. Epub 2017 Feb 1.

Department of Biological Sciences, Columbia University, New York, New York 10027, USA.

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http://dx.doi.org/10.1038/nature21061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302053PMC
February 2017

Constituents from Vitex negundo var. heterophylla and their inhibition of nitric oxide production.

J Nat Med 2017 Jan 17;71(1):292-298. Epub 2016 Aug 17.

Key Laboratory of Structure-Based Drug Design and Discovery, Department of Natural Products Chemistry, School of Traditional Chinese Materia Medica, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, China.

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http://dx.doi.org/10.1007/s11418-016-1032-yDOI Listing
January 2017

Determination of the ribosome structure to a resolution of 2.5 Å by single-particle cryo-EM.

Protein Sci 2017 01 26;26(1):82-92. Epub 2016 Oct 26.

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, 10032.

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http://dx.doi.org/10.1002/pro.3068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192974PMC
January 2017

Blue Light- and Low Temperature-Regulated COR27 and COR28 Play Roles in the Arabidopsis Circadian Clock.

Plant Cell 2016 11 11;28(11):2755-2769. Epub 2016 Nov 11.

National Key Laboratory of Plant Molecular Genetics, CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200032 Shanghai, P.R. China

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http://dx.doi.org/10.1105/tpc.16.00354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155342PMC
November 2016

Correlation of particle properties with cytotoxicity and cellular uptake of hydroxyapatite nanoparticles in human gastric cancer cells.

Mater Sci Eng C Mater Biol Appl 2016 Oct 7;67:453-460. Epub 2016 May 7.

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09284931163045
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http://dx.doi.org/10.1016/j.msec.2016.05.034DOI Listing
October 2016

Cyclic di-AMP targets the cystathionine beta-synthase domain of the osmolyte transporter OpuC.

Mol Microbiol 2016 10 26;102(2):233-243. Epub 2016 Jul 26.

Department of Microbiology, University of Washington, Seattle, WA, 98195, USA.

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http://dx.doi.org/10.1111/mmi.13456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118871PMC
October 2016

A distinct holoenzyme organization for two-subunit pyruvate carboxylase.

Nat Commun 2016 10 6;7:12713. Epub 2016 Oct 6.

Department of Biological Sciences, Columbia University, New York, New York 10027, USA.

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http://dx.doi.org/10.1038/ncomms12713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059739PMC
October 2016

Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit.

Proc Natl Acad Sci U S A 2016 10 10;113(43):12174-12179. Epub 2016 Oct 10.

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032; Department of Biological Sciences, Columbia University, New York, NY 10027; Howard Hughes Medical Institute, Columbia University, New York, NY 10027;

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http://dx.doi.org/10.1073/pnas.1614594113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087005PMC
October 2016

[EMD Time-Frequency Analysis of Raman Spectrum and NIR].

Guang Pu Xue Yu Guang Pu Fen Xi 2016 Feb;36(2):424-9

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February 2016

Structure and substrate selectivity of the 750-kDa α6β6 holoenzyme of geranyl-CoA carboxylase.

Nat Commun 2015 Nov 23;6:8986. Epub 2015 Nov 23.

Department of Biological Sciences, Columbia University, New York, New York 10027, USA.

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http://dx.doi.org/10.1038/ncomms9986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673880PMC
November 2015

Competing endogenous RNA: A novel posttranscriptional regulatory dimension associated with the progression of cancer.

Oncol Lett 2015 Nov 14;10(5):2683-2690. Epub 2015 Sep 14.

Key Laboratory for Medical Molecule Activity Research, Guangdong Medical College, Dongguan, Guangdong 523000, P.R. China.

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http://dx.doi.org/10.3892/ol.2015.3698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665929PMC
November 2015

Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates.

Chembiochem 2015 Oct 9;16(15):2205-2215. Epub 2015 Sep 9.

Department of Medicine/Division of Experimental Therapeutics, Columbia University Medical Center, 630 W. 168th Street, New York, NY 10032 (USA).

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http://doi.wiley.com/10.1002/cbic.201500348
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http://dx.doi.org/10.1002/cbic.201500348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664178PMC
October 2015

Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer.

Authors:
Jia Wei Liang Tong

Nature 2015 Oct 12;526(7575):723-7. Epub 2015 Oct 12.

Department of Biological Sciences, Columbia University, New York, New York 10027, USA.

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http://dx.doi.org/10.1038/nature15375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838907PMC
October 2015

The RAS-Binding Domain of Human BRAF Protein Serine/Threonine Kinase Exhibits Allosteric Conformational Changes upon Binding HRAS.

Structure 2015 Aug 9;23(8):1382-1393. Epub 2015 Jul 9.

Center for Advanced Biotechnology and Medicine, Department of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA; Northeast Structural Genomics Consortium, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA; Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09692126150022
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http://dx.doi.org/10.1016/j.str.2015.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963008PMC
August 2015

Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations.

Nature 2015 Jul 18;523(7558):111-4. Epub 2015 May 18.

Department of Cell and Tissue Biology, University of California, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1038/nature14405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510984PMC
July 2015

Structural and biochemical studies of the distinct activity profiles of Rai1 enzymes.

Nucleic Acids Res 2015 Jul 22;43(13):6596-606. Epub 2015 Jun 22.

Department of Biological Sciences, Columbia University, New York, NY 10027, USA

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http://dx.doi.org/10.1093/nar/gkv620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513879PMC
July 2015

Molecular basis for the recognition of cyclic-di-AMP by PstA, a PII-like signal transduction protein.

Microbiologyopen 2015 Jun 18;4(3):361-74. Epub 2015 Feb 18.

Department of Biological Sciences, Columbia University, New York City, New York, 10027.

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http://dx.doi.org/10.1002/mbo3.243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475381PMC
June 2015

[Adaptive "3R" De-Noising Algorithm Based on Near Infrared Bi-Spectrum].

Guang Pu Xue Yu Guang Pu Fen Xi 2015 Apr;35(4):1146-50

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April 2015

Simultaneous estimation of QTL effects and positions when using genotype data with errors.

J Genet 2015 Mar;94(1):27-34

School of Mathematical Sciences, Heilongjiang University, Harbin 150080, People's Republic of China.

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March 2015

Structure and function of a single-chain, multi-domain long-chain acyl-CoA carboxylase.

Nature 2015 Feb 10;518(7537):120-4. Epub 2014 Nov 10.

Department of Biological Sciences, Columbia University, New York, New York 10027, USA.

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http://www.nature.com/articles/nature13912
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http://dx.doi.org/10.1038/nature13912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319993PMC
February 2015

An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence.

Proc Natl Acad Sci U S A 2015 Feb 12;112(7):E747-56. Epub 2015 Jan 12.

Department of Microbiology, University of Washington, Seattle, WA 98195;

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http://dx.doi.org/10.1073/pnas.1416485112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343097PMC
February 2015

Emergency contrast-enhanced ultrasonography for pancreatic injuries in blunt abdominal trauma.

Radiol Med 2014 Dec 28;119(12):920-927. Epub 2014 May 28.

Department of Emergency, Chinese People's Liberation Army General Hospital, Beijing, China.

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http://dx.doi.org/10.1007/s11547-014-0410-3DOI Listing
December 2014

Multistage regulator based on tandem promoters and CRISPR/Cas.

ACS Synth Biol 2014 Dec;3(12):1007-10

College of Life Sciences, Wuhan University , Wuhan, Hubei 430072, China.

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http://pubs.acs.org/doi/10.1021/sb500029n
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http://dx.doi.org/10.1021/sb500029nDOI Listing
December 2014

Effectiveness of contrast-enhanced ultrasound in the classification and emergency management of abdominal trauma.

Eur Radiol 2014 Oct 9;24(10):2640-8. Epub 2014 Aug 9.

Department of Ultrasound, Chinese People's Liberation Army General Hospital, 28 Fuxing Road, Beijing, 100853, China,

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http://dx.doi.org/10.1007/s00330-014-3232-8DOI Listing
October 2014

Molecular basis for the recognition of methylated adenines in RNA by the eukaryotic YTH domain.

Proc Natl Acad Sci U S A 2014 Sep 8;111(38):13834-9. Epub 2014 Sep 8.

Department of Biological Sciences, Columbia University, New York, NY 10027

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http://www.pnas.org/cgi/doi/10.1073/pnas.1412742111
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http://dx.doi.org/10.1073/pnas.1412742111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183320PMC
September 2014

The ROQ domain of Roquin recognizes mRNA constitutive-decay element and double-stranded RNA.

Nat Struct Mol Biol 2014 Aug 13;21(8):679-85. Epub 2014 Jul 13.

Department of Biological Sciences, Columbia University, New York, New York, USA.

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http://dx.doi.org/10.1038/nsmb.2857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125485PMC
August 2014

The cytoplasmic domain of rat synaptotagmin I enhances synaptic transmission.

Cell Mol Neurobiol 2014 Jul 28;34(5):659-67. Epub 2014 Mar 28.

Department of Biology, York College and Graduate Center, The City University of New York, 94-20 Guy R. Brewer Boulevard, Jamaica, NY, 11451, USA,

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http://dx.doi.org/10.1007/s10571-014-0040-2DOI Listing
July 2014

Molecular mechanisms for the regulation of histone mRNA stem-loop-binding protein by phosphorylation.

Proc Natl Acad Sci U S A 2014 Jul 7;111(29):E2937-46. Epub 2014 Jul 7.

Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709;

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http://dx.doi.org/10.1073/pnas.1406381111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115514PMC
July 2014

Self-assembled conjugated polymer spheres as fluorescent microresonators.

Sci Rep 2014 Jul 31;4:5902. Epub 2014 Jul 31.

Division of Materials Science and Tsukuba Research Center for Interdisciplinary Materials Science (TIMS), Faculty of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573, Japan.

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http://dx.doi.org/10.1038/srep05902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379992PMC
July 2014

MGARP regulates mouse neocortical development via mitochondrial positioning.

Mol Neurobiol 2014 Jun 10;49(3):1293-308. Epub 2013 Dec 10.

State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.

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http://link.springer.com/10.1007/s12035-013-8602-8
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June 2014

Delineating the structural blueprint of the pre-mRNA 3'-end processing machinery.

Mol Cell Biol 2014 Jun 3;34(11):1894-910. Epub 2014 Mar 3.

Department of Biological Sciences, Columbia University, New York, New York, USA.

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http://dx.doi.org/10.1128/MCB.00084-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019069PMC
June 2014

Functional conformations for pyruvate carboxylase during catalysis explored by cryoelectron microscopy.

Structure 2014 Jun 29;22(6):911-22. Epub 2014 May 29.

Structural Biology Unit, Center for Cooperative Research in Biosciences, CIC bioGUNE, 48160 Derio, Spain; Department of Biochemistry and Molecular Biology, University of the Basque Country, P.O. Box 644, 48080 Bilbao, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.str.2014.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090597PMC
June 2014

[Adaptive EEMD residue related baseline correction algorithm].

Guang Pu Xue Yu Guang Pu Fen Xi 2014 Jun;34(6):1624-8

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June 2014

Structure of the Arabidopsis thaliana TOP2 oligopeptidase.

Acta Crystallogr F Struct Biol Commun 2014 May 15;70(Pt 5):555-9. Epub 2014 Apr 15.

Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

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http://dx.doi.org/10.1107/S2053230X14006128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014318PMC
May 2014

Structure and function of pre-mRNA 5'-end capping quality control and 3'-end processing.

Biochemistry 2014 Apr 20;53(12):1882-98. Epub 2014 Mar 20.

Department of Biological Sciences, Columbia University , New York, New York 10027, United States.

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http://dx.doi.org/10.1021/bi401715vDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977584PMC
April 2014

Molecular mechanism for self-protection against the type VI secretion system in Vibrio cholerae.

Acta Crystallogr D Biol Crystallogr 2014 Apr 20;70(Pt 4):1094-103. Epub 2014 Mar 20.

Chinese Academy of Sciences Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, People's Republic of China.

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http://dx.doi.org/10.1107/S1399004714001242DOI Listing
April 2014

Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design.

J Mol Biol 2014 Jan 23;426(1):256-71. Epub 2013 Oct 23.

Department of Biochemistry, University of Washington, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2013.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104579PMC
January 2014

Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair.

Nucleic Acids Res 2013 Dec 3;41(22):10573-83. Epub 2013 Sep 3.

State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China, Graduate School of Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China and Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

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http://dx.doi.org/10.1093/nar/gkt788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905867PMC
December 2013