Li-Xuan Qin

Li-Xuan Qin

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Li-Xuan Qin

Li-Xuan Qin

Publications by authors named "Li-Xuan Qin"

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81Publications

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Yield of Colonoscopy in Identification of Newly Diagnosed Desmoid-Type Fibromatosis with Underlying Familial Adenomatous Polyposis.

Ann Surg Oncol 2019 Mar 4;26(3):765-771. Epub 2019 Jan 4.

Sarcoma Biology Laboratory and Sarcoma Disease Management Team, Sarcoma Disease Management Program, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1245/s10434-018-07138-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380484PMC
March 2019

PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence.

Oncogene 2018 09 23;37(37):5066-5078. Epub 2018 May 23.

Departments of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.

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http://dx.doi.org/10.1038/s41388-018-0332-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137027PMC
September 2018

Empirical evaluation of data normalization methods for molecular classification.

PeerJ 2018 11;6:e4584. Epub 2018 Apr 11.

Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.7717/peerj.4584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899419PMC
April 2018

Cautionary Note on Using Cross-Validation for Molecular Classification.

J Clin Oncol 2016 11;34(32):3931-3938

All authors: Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2016.68.1031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477984PMC
November 2016

Integrin-α10 Dependency Identifies RAC and RICTOR as Therapeutic Targets in High-Grade Myxofibrosarcoma.

Cancer Discov 2016 10 30;6(10):1148-1165. Epub 2016 Aug 30.

Sarcoma Biology Laboratory, Sarcoma Disease Management Program, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York. Department of Surgery, Weill Cornell Medical College, New York, New York.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050162PMC
http://dx.doi.org/10.1158/2159-8290.CD-15-1481DOI Listing
October 2016

Study design and data analysis considerations for the discovery of prognostic molecular biomarkers: a case study of progression free survival in advanced serous ovarian cancer.

BMC Med Genomics 2016 06 10;9(1):27. Epub 2016 Jun 10.

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.

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http://dx.doi.org/10.1186/s12920-016-0187-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901402PMC
June 2016

Empirical insights into the stochasticity of small RNA sequencing.

Sci Rep 2016 Apr 7;6:24061. Epub 2016 Apr 7.

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, USA.

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http://dx.doi.org/10.1038/srep24061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823707PMC
April 2016

Histology-based Classification Predicts Pattern of Recurrence and Improves Risk Stratification in Primary Retroperitoneal Sarcoma.

Ann Surg 2016 Mar;263(3):593-600

*Department of Surgery, Memorial Sloan Kettering Cancer Center, New York City, NY †Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York City, NY ‡Department of Pathology, Memorial Sloan Kettering Cancer Center, New York City, NY.

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http://dx.doi.org/10.1097/SLA.0000000000001149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619189PMC
March 2016

Optimal Percent Myxoid Component to Predict Outcome in High-Grade Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma.

Ann Surg Oncol 2016 Mar 12;23(3):818-25. Epub 2016 Jan 12.

Sarcoma Biology Laboratory, Sarcoma Disease Management Program, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1245/s10434-015-5063-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964786PMC
March 2016

Targeted exome sequencing profiles genetic alterations in leiomyosarcoma.

Genes Chromosomes Cancer 2016 Feb 6;55(2):124-30. Epub 2015 Nov 6.

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1002/gcc.22318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715662PMC
February 2016

Differential Expression Analysis for RNA-Seq: An Overview of Statistical Methods and Computational Software.

Cancer Inform 2015 13;14(Suppl 1):57-67. Epub 2015 Dec 13.

Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.4137/CIN.S21631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678998PMC
December 2015

Preprocessing Steps for Agilent MicroRNA Arrays: Does the Order Matter?

Cancer Inform 2014 3;13(Suppl 4):105-9. Epub 2015 Sep 3.

Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.4137/CIN.S21630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560483PMC
September 2015

Comparison of Perioperative Radiation Therapy and Surgery Versus Surgery Alone in 204 Patients With Primary Retroperitoneal Sarcoma: A Retrospective 2-Institution Study.

Ann Surg 2015 Jul;262(1):156-62

*Department of Surgery, Sarcoma Disease Management Program, Memorial Sloan Kettering Cancer Center, New York, NY †Department of Surgery, Massachusetts General Hospital, Boston, MA ‡Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY §Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA.

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http://pdfs.journals.lww.com/annalsofsurgery/2015/07000/Comp
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/SLA.0000000000001063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465112PMC
July 2015

Gene expression profiling of lobular carcinoma in situ reveals candidate precursor genes for invasion.

Mol Oncol 2015 Apr 24;9(4):772-82. Epub 2014 Dec 24.

Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 300 E. 66th St., New York, NY, 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2014.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387062PMC
April 2015

Array platform modeling and analysis (a).

Cancer Inform 2014 17;13(Suppl 4):91-3. Epub 2015 Feb 17.

Assistant Professor of Statistics, University of Missouri-Columbia, Columbia, MO, USA.

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http://dx.doi.org/10.4137/CIN.S22973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334035PMC
March 2015

Sequencing platform modeling and analysis.

Cancer Inform 2015 2;14(Suppl 1):55-6. Epub 2015 Mar 2.

Assistant Professor of Epidemiology and Biostatistics, Brown University, Providence, RI, USA.

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http://dx.doi.org/10.4137/CIN.S24698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348078PMC
March 2015

Molecular subtypes of uterine leiomyosarcoma and correlation with clinical outcome.

Neoplasia 2015 Feb;17(2):183-9

Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Weill Cornell Medical College, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2014.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351299PMC
February 2015

MicroRNA array normalization: an evaluation using a randomized dataset as the benchmark.

PLoS One 2014 6;9(6):e98879. Epub 2014 Jun 6.

Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098879PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048305PMC
January 2015

CORM: An R Package Implementing the Clustering of Regression Models Method for Gene Clustering.

Cancer Inform 2014 15;13(Suppl 4):11-3. Epub 2014 Oct 15.

Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://journals.sagepub.com/doi/10.4137/CIN.S13967
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http://dx.doi.org/10.4137/CIN.S13967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218679PMC
December 2014

PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors.

Nat Genet 2014 Nov 21;46(11):1227-32. Epub 2014 Sep 21.

1] Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA. [2] Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA. [3] Department of Medicine, Weill Cornell Medical College, New York, New York, USA.

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http://dx.doi.org/10.1038/ng.3095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249650PMC
November 2014

Finding gene clusters for a replicated time course study.

BMC Res Notes 2014 Jan 24;7:60. Epub 2014 Jan 24.

Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1186/1756-0500-7-60DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906880PMC
January 2014

Predictors of survival and recurrence in primary leiomyosarcoma.

Ann Surg Oncol 2013 Jun 25;20(6):1851-7. Epub 2013 Jan 25.

Sarcoma Disease Management Team, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1245/s10434-013-2876-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657306PMC
June 2013

An Empirical Evaluation of Normalization Methods for MicroRNA Arrays in a Liposarcoma Study.

Cancer Inform 2013 18;12:83-101. Epub 2013 Mar 18.

Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.4137/CIN.S11384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615992PMC
April 2013

Cadherin-catenin complex dissociation in lobular neoplasia of the breast.

Breast Cancer Res Treat 2012 Apr 13;132(2):641-52. Epub 2011 Nov 13.

Breast Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 300 E. 66th St., New York, NY 10065, USA.

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http://dx.doi.org/10.1007/s10549-011-1860-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349355PMC
April 2012

Copy number losses define subgroups of dedifferentiated liposarcoma with poor prognosis and genomic instability.

Clin Cancer Res 2012 Mar 12;18(5):1334-40. Epub 2012 Jan 12.

Sarcoma Disease Management Program, Department of Surgery, Bioinformatics Core, Computational Biology Center, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-2820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294014PMC
March 2012

CD133 and CD44 are universally overexpressed in GIST and do not represent cancer stem cell markers.

Genes Chromosomes Cancer 2012 Feb 10;51(2):186-95. Epub 2011 Nov 10.

Department of Pathology, Memorial Sloan-Kettering Cancer Center, NY, USA.

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http://dx.doi.org/10.1002/gcc.20942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366284PMC
February 2012

A microRNA survival signature (MiSS) for advanced ovarian cancer.

Gynecol Oncol 2011 Jun 26;121(3):444-50. Epub 2011 Feb 26.

Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.ygyno.2011.01.025DOI Listing
June 2011

Cyst fluid interleukin-1beta (IL1beta) levels predict the risk of carcinoma in intraductal papillary mucinous neoplasms of the pancreas.

Clin Cancer Res 2011 Mar 25;17(6):1502-8. Epub 2011 Jan 25.

Department of Surgery, Division of Surgical Oncology, University of Illinois at Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-1561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065716PMC
March 2011

Dermatofibrosarcoma protuberans (DFSP): predictors of recurrence and the use of systemic therapy.

Ann Surg Oncol 2011 Feb 16;18(2):328-36. Epub 2010 Sep 16.

Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1245/s10434-010-1316-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310211PMC
February 2011

Differential impact of high-dose cyclophosphamide, topotecan, and vincristine in clinical subsets of patients with chemoresistant neuroblastoma.

Cancer 2010 Jun;116(12):3054-60

Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1002/cncr.25232DOI Listing
June 2010

An integrative analysis of microRNA and mRNA expression--a case study.

Authors:
Li-Xuan Qin

Cancer Inform 2008 17;6:369-79. Epub 2008 Jun 17.

Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2623315PMC
May 2010

Do radiation-associated soft tissue sarcomas have the same prognosis as sporadic soft tissue sarcomas?

J Clin Oncol 2010 Apr 22;28(12):2064-9. Epub 2010 Mar 22.

Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, Howard 1209, New York, NY 10065, USA.

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http://dx.doi.org/10.1200/JCO.2009.25.1728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651600PMC
April 2010

Predicting outcome by growth rate of locally recurrent retroperitoneal liposarcoma: the one centimeter per month rule.

Ann Surg 2009 Dec;250(6):977-82

Soft Tissue Sarcoma Program, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248745PMC
http://dx.doi.org/10.1097/sla.0b013e3181b2468bDOI Listing
December 2009

Budding yeast SSD1-V regulates transcript levels of many longevity genes and extends chronological life span in purified quiescent cells.

Mol Biol Cell 2009 Sep 1;20(17):3851-64. Epub 2009 Jul 1.

Fred Hutchinson Cancer Research Center, Basic Sciences Division, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1091/mbc.e09-04-0347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735484PMC
September 2009

Perineural invasion after preoperative chemotherapy predicts poor survival in patients with locally advanced gastric cancer: gene expression analysis with pathologic validation.

Am J Clin Oncol 2009 Aug;32(4):356-62

Department of Medicine, Gastrointestinal Oncology Service, Memorial Sloan-Kettering Cancer Center and Weill School of Medicine, Cornell University of New York, NY 10021, USA.

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http://dx.doi.org/10.1097/COC.0b013e31818c08e8DOI Listing
August 2009

gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity.

Cancer Res 2009 Jan;69(2):573-82

Department of Medicine, Division of Solid Tumor Oncology, Laboratory of New Drug Development, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242515PMC
January 2009

Why do patients with low-grade soft tissue sarcoma die?

Ann Surg Oncol 2008 Dec 1;15(12):3550-60. Epub 2008 Oct 1.

Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://www.springerlink.com/index/10.1245/s10434-008-0163-0
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http://dx.doi.org/10.1245/s10434-008-0163-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605207PMC
December 2008

The cyclin-dependent kinase inhibitor flavopiridol potentiates the effects of topoisomerase I poisons by suppressing Rad51 expression in a p53-dependent manner.

Cancer Res 2008 Apr;68(7):2312-20

Laboratory of New Drug Development, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-2395DOI Listing
April 2008

Perioperative chemotherapy in patients undergoing pulmonary resection for metastatic soft-tissue sarcoma of the extremity : a retrospective analysis.

Cancer 2007 Nov;110(9):2050-60

Division of Surgical Oncology, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1002/cncr.23023DOI Listing
November 2007

The clustering of regression models method with applications in gene expression data.

Biometrics 2006 Jun;62(2):526-33

Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://doi.wiley.com/10.1111/j.1541-0420.2005.00498.x
Publisher Site
http://dx.doi.org/10.1111/j.1541-0420.2005.00498.xDOI Listing
June 2006

Evaluation of methods for oligonucleotide array data via quantitative real-time PCR.

BMC Bioinformatics 2006 Jan 17;7:23. Epub 2006 Jan 17.

Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1186/1471-2105-7-23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360686PMC
January 2006

Empirical evaluation of data transformations and ranking statistics for microarray analysis.

Nucleic Acids Res 2004 12;32(18):5471-9. Epub 2004 Oct 12.

Department of Biostatistics, University of Washington, F-600 Health Sciences Building 1705 NE Pacific Street, Box 357232, Seattle, WA 98195, USA.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkh866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC524279PMC
October 2004